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    PLAG1 PLAG1 zinc finger [ Homo sapiens (human) ]

    Gene ID: 5324, updated on 27-Aug-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    PLAG1 interacts with GPX4 to conquer vulnerability to sorafenib induced ferroptosis through a PVT1/miR-195-5p axis-dependent manner in hepatocellular carcinoma.

    PLAG1 interacts with GPX4 to conquer vulnerability to sorafenib induced ferroptosis through a PVT1/miR-195-5p axis-dependent manner in hepatocellular carcinoma.
    Li J, Li Y, Wang D, Liao R, Wu Z., Free PMC Article

    07/17/2024
    SOX10-Internal Tandem Duplications and PLAG1 or HMGA2 Fusions Segregate Eccrine-Type and Apocrine-Type Cutaneous Mixed Tumors.

    SOX10-Internal Tandem Duplications and PLAG1 or HMGA2 Fusions Segregate Eccrine-Type and Apocrine-Type Cutaneous Mixed Tumors.
    Macagno N, Kervarrec T, Thanguturi S, Sohier P, Pissaloux D, Mescam L, Jullie ML, Frouin E, Osio A, Faisant M, Le Loarer F, Cribier B, Calonje E, Luna EVE, Massi D, Goto K, Nishida H, Paindavoine S, Houlier A, Tantot J, Benzerdjeb N, Tirode F, De la Fouchardière A, Battistella M.

    03/26/2024
    Pleomorphic adenoma with extensive squamous and mucinous metaplasia and a novel MALAT1::PLAG1 fusion gene.

    Pleomorphic adenoma with extensive squamous and mucinous metaplasia and a novel MALAT1::PLAG1 fusion gene.
    Gonzalez MF.

    02/13/2024
    PLAG1 dampens protein synthesis to promote human hematopoietic stem cell self-renewal.

    PLAG1 dampens protein synthesis to promote human hematopoietic stem cell self-renewal.
    Keyvani Chahi A, Belew MS, Xu J, Chen HTT, Rentas S, Voisin V, Krivdova G, Lechman E, Marhon SA, De Carvalho DD, Dick JE, Bader GD, Hope KJ., Free PMC Article

    09/17/2022
    Pleomorphic adenoma: detection of PLAG1 rearrangement-positive tumor components using whole-slide fluorescence in situ hybridization.

    Pleomorphic adenoma: detection of PLAG1 rearrangement-positive tumor components using whole-slide fluorescence in situ hybridization.
    Murase T, Ishibashi K, Okumura Y, Ueda K, Nakano S, Fujii K, Masaki A, Nagao T, Inagaki H.

    05/14/2022
    Some pleomorphic adenomas of the breast share PLAG1 rearrangements with the analogous tumour of the salivary glands.

    Some pleomorphic adenomas of the breast share PLAG1 rearrangements with the analogous tumour of the salivary glands.
    Ma S, Zhao D, Liu Y, Rohr J, Zhang F, Ma Y, Gong L, Shi H, Wang Y, Fan L, Qin J, Wang Z, Guo S.

    03/5/2022
    Malignant transformation of salivary gland pleomorphic adenoma: proof of principle.

    Malignant transformation of salivary gland pleomorphic adenoma: proof of principle.
    Valstar MH, Mast H, Ten Hove I, Moonen LR, Balm AJ, Smeele LE, Koljenović S, Dinjens WN, van Velthuysen MF., Free PMC Article

    02/19/2022
    Pediatric fibromyxoid soft tissue tumor with PLAG1 fusion: A novel entity?

    Pediatric fibromyxoid soft tissue tumor with PLAG1 fusion: A novel entity?
    Chung CT, Antonescu CR, Dickson BC, Chami R, Marrano P, Fan R, Shago M, Hameed M, Thorner PS., Free PMC Article

    02/19/2022
    Recent advances in smooth muscle tumors with PGR and PLAG1 gene fusions and myofibroblastic uterine neoplasms.

    Recent advances in smooth muscle tumors with PGR and PLAG1 gene fusions and myofibroblastic uterine neoplasms.
    Chiang S.

    02/12/2022
    The histological and molecular spectrum of lipoblastoma: A case series with identification of three novel gene fusions by targeted RNA-sequencing.

    The histological and molecular spectrum of lipoblastoma: A case series with identification of three novel gene fusions by targeted RNA-sequencing.
    Gerhard-Hartmann E, Vokuhl C, Roth S, Steinmüller T, Rosenfeldt M, Zamò A, Rosenwald A, Appenzeller S, Ernestus K, Maurus K.

    01/29/2022
    Further heterogeneity in Silver-Russell syndrome: PLAG1 deletion in association with a complex chromosomal rearrangement.

    Further heterogeneity in Silver-Russell syndrome: PLAG1 deletion in association with a complex chromosomal rearrangement.
    Brereton RE, Nickerson SL, Woodward KJ, Edwards T, Sivamoorthy S, Ramos Vasques Walters F, Chabros V, Marchin V, Grumball T, Kennedy D, Uzaraga J, Peverall J, Arscott G, Beilby J, Choong CS, Townshend S, Azmanov DN.

    01/22/2022
    FTO and PLAG1 Genes Expression and FTO Methylation Predict Changes in Circulating Levels of Adipokines and Gastrointestinal Peptides in Children.

    FTO and PLAG1 Genes Expression and FTO Methylation Predict Changes in Circulating Levels of Adipokines and Gastrointestinal Peptides in Children.
    Czogała W, Strojny W, Schab M, Grabowska A, Miklusiak K, Kowalczyk W, Łazarczyk A, Tomasik P, Skoczeń S., Free PMC Article

    11/22/2021
    Lipoblastomas presenting in older children and adults: analysis of 22 cases with identification of novel PLAG1 fusion partners.

    Lipoblastomas presenting in older children and adults: analysis of 22 cases with identification of novel PLAG1 fusion partners.
    Fritchie K, Wang L, Yin Z, Nakitandwe J, Hedges D, Horvai A, Mora JT, Folpe AL, Bahrami A.

    11/6/2021
    Methylation and Expression of FTO and PLAG1 Genes in Childhood Obesity: Insight into Anthropometric Parameters and Glucose-Lipid Metabolism.

    Methylation and Expression of FTO and PLAG1 Genes in Childhood Obesity: Insight into Anthropometric Parameters and Glucose-Lipid Metabolism.
    Czogała W, Czogała M, Strojny W, Wątor G, Wołkow P, Wójcik M, Bik Multanowski M, Tomasik P, Wędrychowicz A, Kowalczyk W, Miklusiak K, Łazarczyk A, Hałubiec P, Skoczeń S., Free PMC Article

    08/7/2021
    Novel Variant in PLAG1 in a Familial Case with Silver-Russell Syndrome Suspicion.

    Novel Variant in PLAG1 in a Familial Case with Silver-Russell Syndrome Suspicion.
    Vado Y, Pereda A, Llano-Rivas I, Gorria-Redondo N, Díez I, Perez de Nanclares G., Free PMC Article

    07/24/2021
    MicroRNA-21-5p promotes the inflammatory response after spinal cord injury by targeting PLAG1.

    MicroRNA-21-5p promotes the inflammatory response after spinal cord injury by targeting PLAG1.
    Han K, Wang FR, Yu MQ.

    04/24/2021
    Molecular Profiling of Clear Cell Myoepithelial Carcinoma of Salivary Glands With EWSR1 Rearrangement Identifies Frequent PLAG1 Gene Fusions But No EWSR1 Fusion Transcripts.

    Molecular Profiling of Clear Cell Myoepithelial Carcinoma of Salivary Glands With EWSR1 Rearrangement Identifies Frequent PLAG1 Gene Fusions But No EWSR1 Fusion Transcripts.
    Skálová A, Agaimy A, Vanecek T, Baněčková M, Laco J, Ptáková N, Šteiner P, Majewska H, Biernat W, Corcione L, Eis V, Koshyk O, Vondrák J Jr, Michal M, Leivo I.

    02/2/2021
    Bayesian Modeling Identifies PLAG1 as a Key Regulator of Proliferation and Survival in Rhabdomyosarcoma Cells.

    Bayesian Modeling Identifies PLAG1 as a Key Regulator of Proliferation and Survival in Rhabdomyosarcoma Cells.
    Zheng Y, Xu L, Hassan M, Zhou X, Zhou Q, Rakheja D, Skapek SX., Free PMC Article

    01/23/2021
    Differential Expression of PLAG1 in Apocrine and Eccrine Cutaneous Mixed Tumors: Evidence for Distinct Molecular Pathogenesis.

    Differential Expression of PLAG1 in Apocrine and Eccrine Cutaneous Mixed Tumors: Evidence for Distinct Molecular Pathogenesis.
    Russell-Goldman E, Dubuc A, Hanna J.

    01/16/2021
    PLAG1 silencing promotes cell chemosensitivity in ovarian cancer via the IGF2 signaling pathway.

    PLAG1 silencing promotes cell chemosensitivity in ovarian cancer via the IGF2 signaling pathway.
    Huang W, Li BR, Feng H., Free PMC Article

    12/5/2020
    Undifferentiated myxoid lipoblastoma with PLAG1 gene rearrangement in infant.

    Undifferentiated myxoid lipoblastoma with PLAG1 gene rearrangement in infant.
    Zhou J, Li X, Cai Y, Wang L, Yang SD.

    11/28/2020
    Metastasizing pleomorphic adenomas with recurrent PLAG1/HMGA2 gene rearrangements and a novel HMGA2-TMTC2 fusion.

    Metastasizing Pleomorphic Adenoma: Recurrent PLAG1/HMGA2 Rearrangements and Identification of a Novel HMGA2-TMTC2 Fusion.
    Wasserman JK, Dickson BC, Smith A, Swanson D, Purgina BM, Weinreb I.

    03/28/2020
    Transcriptomic analysis showed that Plag1 increases the expression of a set of neuronal genes in NPCs.

    Plag1 regulates neuronal gene expression and neuronal differentiation of neocortical neural progenitor cells.
    Sakai H, Fujii Y, Kuwayama N, Kawaji K, Gotoh Y, Kishi Y.

    02/1/2020
    PLAG1 rearrangements resulting in PLAG1 expression underpin ~25% of uterine myxoid leiomyosarcomas and may serve as a useful diagnostic biomarker

    Novel PLAG1 Gene Rearrangement Distinguishes a Subset of Uterine Myxoid Leiomyosarcoma From Other Uterine Myxoid Mesenchymal Tumors.
    Arias-Stella JA 3rd, Benayed R, Oliva E, Young RH, Hoang LN, Lee CH, Jungbluth AA, Frosina D, Soslow RA, Antonescu CR, Ladanyi M, Chiang S., Free PMC Article

    01/11/2020
    The mechanisms of PLAG1 transcriptional upregulation in lipoblastoma pathogenesis.

    Three Novel Aberrations Involving PLAG1 Leading to Lipoblastoma in Three Different Patients: High Amplification, Partial Deletion, and a Unique Complex Rearrangement.
    Wang G, Guzman MA, Batanian JR.

    01/11/2020
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