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    ABCB1 ATP binding cassette subfamily B member 1 [ Homo sapiens (human) ]

    Gene ID: 5243, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The Frequencies distribution of CYP3A5 rs776746 and ABCB1 rs1045642 polymorphisms in the west Algerian population and relationships with pharmacogenetics.

    The Frequencies distribution of CYP3A5 rs776746 and ABCB1 rs1045642 polymorphisms in the west Algerian population and relationships with pharmacogenetics.
    Ammour A, Aberkane M, Boudjema A, Boughrara W, Benchekor SM., Free PMC Article

    10/1/2024
    Characterization of Chemoresistance in Pancreatic Cancer: A Look at MDR-1 Polymorphisms and Expression in Cancer Cells and Patients.

    Characterization of Chemoresistance in Pancreatic Cancer: A Look at MDR-1 Polymorphisms and Expression in Cancer Cells and Patients.
    Girolimetti G, Balena B, Cordella P, Verri T, Eusebi LH, Bozzetti MP, Bucci C, Guerra F., Free PMC Article

    09/18/2024
    Influence of (C1236T and C3435T) Polymorphisms of ABCB1 Gene on Chemotherapy Treatment Outcome and Toxicity in Breast Cancer Patients.

    Influence of (C1236T and C3435T) Polymorphisms of ABCB1 Gene on Chemotherapy Treatment Outcome and Toxicity in Breast Cancer Patients.
    Gudur RA, Bhosale SJ, Gudur AK, Kale SR, More AL, Datkhile KD., Free PMC Article

    09/18/2024
    Membrane P-glycoprotein expression in lymphocytes from adult patients with refractory glomerulonephritis.

    Membrane P-glycoprotein expression in lymphocytes from adult patients with refractory glomerulonephritis.
    Jin S, Zou X, Xue X, Chen S, Wang X, Xu W.

    08/28/2024
    Relation between ABCB1 overexpression and COX2 and ALOX5 genes in human erythroleukemia cell lines.

    Relation between ABCB1 overexpression and COX2 and ALOX5 genes in human erythroleukemia cell lines.
    Salgado MTSF, Lopes AC, Fernandes E Silva E, Cardoso JQ, Vidal RS, Cavalcante-Silva LHA, Carvalho DCM, Machado KDS, Rodrigues-Mascarenhas S, Rumjanek VM, Votto APS.

    08/26/2024
    Influence of GPRC5A-Regulated ABCB1 Expression on Lung Adenocarcinoma Proliferation.

    Influence of GPRC5A-Regulated ABCB1 Expression on Lung Adenocarcinoma Proliferation.
    Li Y, Cui WW, Yang ZF, Liu WH, Bian MW, Deng J, Wang T.

    05/7/2024
    Common P-glycoprotein (ABCB1) polymorphisms do not seem to be associated with the risk of rivaroxaban-related bleeding events: Preliminary data.

    Common P-glycoprotein (ABCB1) polymorphisms do not seem to be associated with the risk of rivaroxaban-related bleeding events: Preliminary data.
    Slišković AM, Palić J, Božina T, Ganoci L, Vrkić Kirhmajer M, Trkulja V, Bulum J, Šimičević L., Free PMC Article

    04/30/2024
    NAT10-mediated mRNA N4-acetylcytidine modification of MDR1 and BCRP promotes breast cancer progression.

    NAT10-mediated mRNA N4-acetylcytidine modification of MDR1 and BCRP promotes breast cancer progression.
    Zhao CC, Sun X, Chen J, Geng BD., Free PMC Article

    04/11/2024
    Association of variants in the ABCB1, CYP2C19 and CYP2C9 genes for Juvenile Myoclonic Epilepsy.

    Association of variants in the ABCB1, CYP2C19 and CYP2C9 genes for Juvenile Myoclonic Epilepsy.
    Jara-Prado A, Guerrero-Camacho JL, Ángeles-López QD, Ochoa-Morales A, Dávila-Ortiz de Montellano DJ, Ramírez-García MÁ, Breda-Yepes M, Durón RM, Delgado-Escueta AV, Barrios-González DA, Martínez-Juárez IE.

    03/18/2024
    The Effect of Platelet Activity, ABCB1 Genetic Polymorphism, and Renal Function on the Development of Ticagrelor-Related Dyspnea in Patients with Acute Coronary Syndrome.

    The Effect of Platelet Activity, ABCB1 Genetic Polymorphism, and Renal Function on the Development of Ticagrelor-Related Dyspnea in Patients with Acute Coronary Syndrome.
    Tamakauskas V, Žaliūnas R, Lesauskaitė V, Kupstytė-Krištaponė N, Čiapienė I, Šakalytė G, Plisienė J, Skipskis V, Tatarūnas V., Free PMC Article

    03/1/2024
    The association of ABCB1 gene polymorphism with clinical response to carbamazepine monotherapy in patients with epilepsy.

    The association of ABCB1 gene polymorphism with clinical response to carbamazepine monotherapy in patients with epilepsy.
    Rashid HU, Ullah S, Carr DF, Khattak MIK, Asad MI, Rehman MU, Tipu MK.

    02/27/2024
    Exploring the dynamics of the ABCB1 membrane transporter P-glycoprotein in the presence of ATP and active/non-active compounds through molecular dynamics simulations.

    Exploring the dynamics of the ABCB1 membrane transporter P-glycoprotein in the presence of ATP and active/non-active compounds through molecular dynamics simulations.
    Mora Lagares L, Pérez-Castillo Y, Novič M.

    02/21/2024
    Intestinal P-gp activity is reduced in postmenopausal women under breast cancer therapy.

    Intestinal P-gp activity is reduced in postmenopausal women under breast cancer therapy.
    Ximenez JPB, de Andrade JM, Rocha A, Barbosa Coelho E, Suarez-Kurtz G, Lanchote VL., Free PMC Article

    02/5/2024
    Population pharmacokinetics of lenalidomide in Chinese patients with influence of genetic polymorphisms of ABCB1.

    Population pharmacokinetics of lenalidomide in Chinese patients with influence of genetic polymorphisms of ABCB1.
    Liang X, Shi H, Bi K, Feng S, Chen S, Zhao W, Huang X., Free PMC Article

    02/2/2024
    The Impact of ABCB1 SNPs on Tacrolimus Pharmacokinetics in Liver or Kidney Transplant Recipients: A Meta-analysis.

    The Impact of ABCB1 SNPs on Tacrolimus Pharmacokinetics in Liver or Kidney Transplant Recipients: A Meta-analysis.
    Li Z, Wang X, Li D, Cheng S, Dong Y, Yang H, Li X.

    12/14/2023
    Development and Functional Evaluation of MDR1-expressing Microvascular Endothelial-like Cells Derived from Human iPS Cells as an In vitro Blood-brain Barrier Model.

    Development and Functional Evaluation of MDR1-expressing Microvascular Endothelial-like Cells Derived from Human iPS Cells as an In vitro Blood-brain Barrier Model.
    Yamaguchi T, Sako D, Kurosawa T, Nishijima M, Miyano A, Kubo Y, Ohtsuki S, Kawabata K, Deguchi Y.

    11/22/2023
    circ_0002060 Enhances Doxorubicin Resistance in Osteosarcoma by Regulating the miR-198/ABCB1 Axis.

    circ_0002060 Enhances Doxorubicin Resistance in Osteosarcoma by Regulating the miR-198/ABCB1 Axis.
    Ji Y, Liu J, Zhu W, Ji J.

    11/15/2023
    High and Low Levels of ABCB1 Expression Are Associated with Two Distinct Gene Signatures in Lung Tissue of Pulmonary TB Patients with High Inflammation Activity.

    High and Low Levels of ABCB1 Expression Are Associated with Two Distinct Gene Signatures in Lung Tissue of Pulmonary TB Patients with High Inflammation Activity.
    Pavlova EN, Lepekha LN, Rybalkina EY, Tarasov RV, Sychevskaya KA, Voronezhskaya EE, Masyutin AG, Ergeshov AE, Erokhina MV., Free PMC Article

    11/7/2023
    Phosphorylation of rpS3 by Lyn increases translation of Multi-Drug Resistance (MDR1) gene.

    Phosphorylation of rpS3 by Lyn increases translation of Multi-Drug Resistance (MDR1) gene.
    Ahn WS, Kim HD, Kim TS, Ahn MJ, Park YJ, Kim J., Free PMC Article

    10/28/2023
    Association between alpha-defensin 5 and the expression and function of P-glycoprotein in differentiated intestinal Caco-2 cells.

    Association between α-defensin 5 and the expression and function of P-glycoprotein in differentiated intestinal Caco-2 cells.
    Yasuda G, Kubota A, Okamoto K, Narumi K, Furugen A, Kato I, Mori A, Saito Y, Satoh T, Takahashi-Suzuki N, Iseki K, Kobayashi M.

    10/5/2023
    Molecular aspects of ABCB1 and ABCG2 in Gallbladder cancer and its clinical relevance.

    Molecular aspects of ABCB1 and ABCG2 in Gallbladder cancer and its clinical relevance.
    Nimisha, Saluja SS, Sharma AK, Nekarakanti PK, Apurva, Kumar A, Sattar RSA, Anjum H, Batra VV, Husain SA.

    09/27/2023
    ABCB1 and ABCG2 Regulation at the Blood-Brain Barrier: Potential New Targets to Improve Brain Drug Delivery.

    ABCB1 and ABCG2 Regulation at the Blood-Brain Barrier: Potential New Targets to Improve Brain Drug Delivery.
    Schulz JA, Hartz AMS, Bauer B., Free PMC Article

    08/17/2023
    The Influence of MDR1 Expression Regulated by miR-138 through TRPS1 Signaling Pathway on Multidrug Resistance of Osteosarcoma and Formation of Bacterial Infection Biofilm.

    The Influence of MDR1 Expression Regulated by miR-138 through TRPS1 Signaling Pathway on Multidrug Resistance of Osteosarcoma and Formation of Bacterial Infection Biofilm.
    Fang X, Zhu L, Wu Q, Zhong X, Chen Y, Zhu W.

    08/14/2023
    The impact of ABCB1, CYP3A4/5 and ABCG2 gene polymorphisms on rivaroxaban trough concentrations and bleeding events in patients with non-valvular atrial fibrillation.

    The impact of ABCB1, CYP3A4/5 and ABCG2 gene polymorphisms on rivaroxaban trough concentrations and bleeding events in patients with non-valvular atrial fibrillation.
    Wu T, Wu S, Li L, Xiang J, Wang N, Chen W, Zhang J., Free PMC Article

    07/12/2023
    The Distribution of the Genotypes of ABCB1 and CES1 Polymorphisms in Kazakhstani Patients with Atrial Fibrillation Treated with DOAC.

    The Distribution of the Genotypes of ABCB1 and CES1 Polymorphisms in Kazakhstani Patients with Atrial Fibrillation Treated with DOAC.
    Abdrakhmanov A, Akilzhanova A, Shaimerdinova A, Zhalbinova M, Tuyakova G, Abildinova S, Albayev R, Ainabekova B, Chinybayeva A, Suleimen Z, Bekbossynova M., Free PMC Article

    06/30/2023
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