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    ERAP1 endoplasmic reticulum aminopeptidase 1 [ Homo sapiens (human) ]

    Gene ID: 51752, updated on 10-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Association of Endoplasmic Reticulum Aminopeptidase 1 Gene Polymorphism with Susceptibility and Severity of Axial Spondyloarthritis in Egyptian Population: A Single-center Case-Control Study.

    Association of Endoplasmic Reticulum Aminopeptidase 1 Gene Polymorphism with Susceptibility and Severity of Axial Spondyloarthritis in Egyptian Population: A Single-center Case-Control Study.
    Saad MA, Abdul-Sattar AB, Abdelal IT, Barak A., Free PMC Article

    08/20/2024
    [Relationship between maternal and fetal ERAP-1 gene polymorphism and pre-eclampsia].

    [Relationship between maternal and fetal ERAP-1 gene polymorphism and pre-eclampsia].
    Ma C, Liu XW, Zheng YY, Zhang WY.

    07/22/2024
    Association of a single nucleotide polymorphism (rs27434) in the ERAP1 gene with plural tissue weight.

    Association of a single nucleotide polymorphism (rs27434) in the ERAP1 gene with plural tissue weight.
    Sasaki T, Razia S, Kimura-Kataoka K, Araki T, Kusaka A, Takeshita H, Fujihara J.

    07/8/2024
    Role of endoplasmic reticulum aminopeptidase-1 gene polymorphism (rs13167972) in occurrence susceptibility of ankylosing spondylitis in a sample of Iraqi male patients.

    Role of endoplasmic reticulum aminopeptidase-1 gene polymorphism (rs13167972) in occurrence susceptibility of ankylosing spondylitis in a sample of Iraqi male patients.
    Hassan SH, Auda IG, Ali EN, Alosami MH, Hussein RH.

    04/3/2024
    A genetic variant in the immune-related gene ERAP1 affects colorectal cancer prognosis.

    A genetic variant in the immune-related gene ERAP1 affects colorectal cancer prognosis.
    Zou D, Cai Y, Jin M, Zhang M, Liu Y, Chen S, Yang S, Zhang H, Zhu X, Huang C, Zhu Y, Miao X, Wei Y, Yang X, Tian J., Free PMC Article

    02/22/2024
    Evolutionary immuno-genetics of endoplasmic reticulum aminopeptidase II (ERAP2).

    Evolutionary immuno-genetics of endoplasmic reticulum aminopeptidase II (ERAP2).
    Raja A, Kuiper JJW., Free PMC Article

    01/12/2024
    Structure-guided discovery of aminopeptidase ERAP1 variants capable of processing antigens with novel PC anchor specificities.

    Structure-guided discovery of aminopeptidase ERAP1 variants capable of processing antigens with novel PC anchor specificities.
    Pande S, Guo HC.,

    12/6/2023
    ERAP1 and ERAP2 Haplotypes Influence Suboptimal HLA-B*27:05-Restricted Anti-Viral CD8+ T Cell Responses Cross-Reactive to Self-Epitopes.

    ERAP1 and ERAP2 Haplotypes Influence Suboptimal HLA-B*27:05-Restricted Anti-Viral CD8+ T Cell Responses Cross-Reactive to Self-Epitopes.
    Tedeschi V, Paldino G, Alba J, Molteni E, Paladini F, Scrivo R, Congia M, Cauli A, Caccavale R, Paroli M, Di Franco M, Tuosto L, Sorrentino R, D'Abramo M, Fiorillo MT., Free PMC Article

    09/18/2023
    Cell-Specific and Variant-Linked Alterations in Expression of ERAP1, ERAP2, and LNPEP Aminopeptidases in Psoriasis.

    Cell-Specific and Variant-Linked Alterations in Expression of ERAP1, ERAP2, and LNPEP Aminopeptidases in Psoriasis.
    Marusina AI, Ji-Xu A, Le ST, Toussi A, Tsoi LC, Li Q, Luxardi G, Nava J, Downing L, Leal AR, Kuzminykh NY, Kruglinskaya O, Brüggen MC, Adamopoulos IE, Merleev AA, Gudjonsson JE, Maverakis E.

    06/26/2023
    Down-regulation of ERAP1 mRNA expression in non-small cell lung cancer.

    Down-regulation of ERAP1 mRNA expression in non-small cell lung cancer.
    Wagner M, Sobczyński M, Jasek M, Pawełczyk K, Porębska I, Kuśnierczyk P, Wiśniewski A., Free PMC Article

    05/3/2023
    Shedding new light on the role of ERAP1 in Type 1 diabetes: A perspective on disease management.

    Shedding new light on the role of ERAP1 in Type 1 diabetes: A perspective on disease management.
    Paldino G, Fierabracci A.

    03/23/2023
    A Comparative Review of Pregnancy and Cancer and Their Association with Endoplasmic Reticulum Aminopeptidase 1 and 2.

    A Comparative Review of Pregnancy and Cancer and Their Association with Endoplasmic Reticulum Aminopeptidase 1 and 2.
    Hur B, Wong V, Lee ED., Free PMC Article

    03/2/2023
    Genetic polymorphisms of Endoplasmic reticulum amino peptidase 1 (ERAP1) and Interferon lambda 4 (IFN-lambda4) in Egyptian patients with type 1 diabetes mellitus.

    Genetic polymorphisms of Endoplasmic reticulum amino peptidase 1 (ERAP1) and Interferon lambda 4 (IFN-λ4) in Egyptian patients with type 1 diabetes mellitus.
    Abo El Nazar S, Ghazy AA, Amer I, Tawfik S, Nassar M, Osman EM.

    01/11/2023
    The ER Aminopeptidases, ERAP1 and ERAP2, synergize to self-modulate their respective activities.

    The ER Aminopeptidases, ERAP1 and ERAP2, synergize to self-modulate their respective activities.
    Martín-Esteban A, Rodriguez JC, Peske D, Lopez de Castro JA, Shastri N, Sadegh-Nasseri S., Free PMC Article

    12/31/2022
    Structural and biochemical insights into the association between ERAP1 polymorphism and autoimmune diseases.

    Structural and biochemical insights into the association between ERAP1 polymorphism and autoimmune diseases.
    Liu S, Lu J, Wu J, Feng D, Wang Y, Su X, Cao H.

    11/5/2022
    Behcet's disease risk-variant HLA-B51/ERAP1-Hap10 alters human CD8 T cell immunity.

    Behçet's disease risk-variant HLA-B51/ERAP1-Hap10 alters human CD8 T cell immunity.
    Cavers A, Kugler MC, Ozguler Y, Al-Obeidi AF, Hatemi G, Ueberheide BM, Ucar D, Manches O, Nowatzky J., Free PMC Article

    10/22/2022
    Functional ERAP1 Variants Distinctively Associate with Ankylosing Spondylitis Susceptibility under the Influence of HLA-B27 in Taiwanese.

    Functional ERAP1 Variants Distinctively Associate with Ankylosing Spondylitis Susceptibility under the Influence of HLA-B27 in Taiwanese.
    Wang CM, Liu MK, Jan Wu YJ, Lin JC, Zheng JW, Wu J, Chen JY., Free PMC Article

    08/27/2022
    Ankylosing Spondylitis Patients Display Aberrant ERAP1 Gene DNA Methylation and Expression.

    Ankylosing Spondylitis Patients Display Aberrant ERAP1 Gene DNA Methylation and Expression.
    Ma Y, Fan D, Xu S, Deng J, Gao X, Guan S, Zhang X, Pan F.

    08/27/2022
    Associations between ERAP1 polymorphisms and ankylosing spondylitis susceptibility in HLA-B27 positive population: a Meta-analysis and bioinformatics analysis.

    Associations between ERAP1 polymorphisms and ankylosing spondylitis susceptibility in HLA-B27 positive population: a Meta-analysis and bioinformatics analysis.
    Bai Y, Zhao N, Sun H, Yin L, Chen J, Hu N.

    07/2/2022
    ERAP1 as an emerging therapeutic target for medulloblastoma.

    ERAP1 as an emerging therapeutic target for medulloblastoma.
    Bufalieri F, Fruci D, Di Marcotullio L.

    04/9/2022
    A proposed HLA-B*27 screening method for ankylosing spondylitis detection based on tag-single nucleotide polymorphisms: a preliminary study.

    A proposed HLA-B*27 screening method for ankylosing spondylitis detection based on tag-single nucleotide polymorphisms: a preliminary study.
    Martínez-Nava GA, Zamudio-Cuevas Y, Terrazas-Ontiveros NA, Martínez-Flores K, Espinosa-Morales R, Mijares-Díaz F, Juárez-Barreto SM, Lozada-Pérez C, Valdés-Flores M, Sánchez-Sánchez R, Hidalgo-Bravo A, Fernández-Torres J.

    03/5/2022
    ERAP1 Controls the Interaction of the Inhibitory Receptor KIR3DL1 With HLA-B51:01 by Affecting Natural Killer Cell Function.

    ERAP1 Controls the Interaction of the Inhibitory Receptor KIR3DL1 With HLA-B51:01 by Affecting Natural Killer Cell Function.
    D'Amico S, D'Alicandro V, Compagnone M, Tempora P, Guida G, Romania P, Lucarini V, Melaiu O, Falco M, Algeri M, Pende D, Cifaldi L, Fruci D., Free PMC Article

    02/19/2022
    Genetic contribution of endoplasmic reticulum aminopeptidase 1 polymorphisms to liver fibrosis progression in patients with HCV infection.

    Genetic contribution of endoplasmic reticulum aminopeptidase 1 polymorphisms to liver fibrosis progression in patients with HCV infection.
    Vidal-Castiñeira JR, López-Vázquez A, Diaz-Bulnes P, Díaz-Coto S, Márquez-Kisinousky L, Martínez-Borra J, Navascues CA, Sanz-Cameno P, de la Vega J, Astudillo A, Rodríguez M, López-Larrea C.

    12/25/2021
    Allotypic variation in antigen processing controls antigenic peptide generation from SARS-CoV-2 S1 spike glycoprotein.

    Allotypic variation in antigen processing controls antigenic peptide generation from SARS-CoV-2 S1 spike glycoprotein.
    Stamatakis G, Samiotaki M, Temponeras I, Panayotou G, Stratikos E., Free PMC Article

    12/11/2021
    ERAP1, ERAP2, and Two Copies of HLA-Aw19 Alleles Increase the Risk for Birdshot Chorioretinopathy in HLA-A29 Carriers.

    ERAP1, ERAP2, and Two Copies of HLA-Aw19 Alleles Increase the Risk for Birdshot Chorioretinopathy in HLA-A29 Carriers.
    Gelfman S, Monnet D, Ligocki AJ, Tabary T, Moscati A, Bai X, Freudenberg J, Cooper B, Kosmicki JA, Wolf S, Ferreira MAR, Overton J, Weyne J, Stahl EA, Baras A, Romano C, Cohen JHM, Coppola G, Brézin A, Regeneron Genetics Center., Free PMC Article

    11/27/2021
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