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    PECAM1 platelet and endothelial cell adhesion molecule 1 [ Homo sapiens (human) ]

    Gene ID: 5175, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Increased shedding of PECAM-1 associated with elevated serum MMP-14 levels as new blood indicators of dengue disease manifestation.

    Increased shedding of PECAM-1 associated with elevated serum MMP-14 levels as new blood indicators of dengue disease manifestation.
    Mariappan V, Shanmugam L, Ranganathan Green S, Easow JM, Mutheneni SR, Thirugnanasambandhar Sivasubramanian A, Balakrishna Pillai A.

    10/25/2024
    Expression of CD31, CD34, and smooth muscle actin (SMA) in endothelial cells of dental pulp vessels.

    Expression of CD31, CD34, and smooth muscle actin (SMA) in endothelial cells of dental pulp vessels.
    Tenyi A, Milutinović A, Nemeth L., Free PMC Article

    09/9/2024
    Effects of Nox4 upregulation on PECAM-1 expression in a mouse model of diabetic retinopathy.

    Effects of Nox4 upregulation on PECAM-1 expression in a mouse model of diabetic retinopathy.
    Wang J, Lai DA, Wang JJ, Zhang SX., Free PMC Article

    07/31/2024
    CD31 defines a subpopulation of human adipose-derived regenerative cells with potent angiogenic effects.

    CD31 defines a subpopulation of human adipose-derived regenerative cells with potent angiogenic effects.
    Dhumale P, Nielsen JV, Hansen ACS, Burton M, Beck HC, Jørgensen MG, Toyserkani NM, Haahr MK, Hansen ST, Lund L, Thomassen M, Sørensen JA, Andersen DC, Jensen CH, Sheikh SP., Free PMC Article

    09/11/2023
    PECAM-1 drives beta-catenin-mediated EndMT via internalization in colon cancer with diabetes mellitus.

    PECAM-1 drives β-catenin-mediated EndMT via internalization in colon cancer with diabetes mellitus.
    Wu Q, Du X, Cheng J, Qi X, Liu H, Lv X, Gong X, Shao C, Wang M, Yue L, Yang X, Li S, Zhang Y, Li X, Yang H., Free PMC Article

    08/17/2023
    CD31 as a probable responding and gate-keeping protein of the blood-brain barrier and the risk of Alzheimer's disease.

    CD31 as a probable responding and gate-keeping protein of the blood-brain barrier and the risk of Alzheimer's disease.
    Zhang Z, Gan Q, Han J, Tao Q, Qiu WQ, Madri JA., Free PMC Article

    06/30/2023
    Elevated shear rate-induced by exercise increases eNOS ser[1177] but not PECAM-1 Tyr[713] phosphorylation in human conduit artery endothelial cells.

    Elevated shear rate-induced by exercise increases eNOS ser(1177) but not PECAM-1 Tyr(713) phosphorylation in human conduit artery endothelial cells.
    Tryfonos A, Rasoul D, Sadler D, Shelley J, Mills J, Green DJ, Dawson EA, Cocks M.

    04/12/2023
    Colon tumor CD31 expression is associated with higher disease-free survival in patients with metabolic syndrome.

    Colon tumor CD31 expression is associated with higher disease-free survival in patients with metabolic syndrome.
    Silva A, Pereira SS, Brandão JR, Brochado P, Monteiro MP, Araújo A, Faria G.

    12/10/2022
    Immunohistochemical analysis of CD31 expression in myocardial tissues from autopsies of patients with ischemic heart disease.

    Immunohistochemical analysis of CD31 expression in myocardial tissues from autopsies of patients with ischemic heart disease.
    Kondo T, Takahashi M, Yamasaki G, Sugimoto M, Kuse A, Morichika M, Nakagawa K, Sakurada M, Asano M, Ueno Y.

    10/29/2022
    The expression pattern of CD10 and CD31 identifies fine fibrovascular stroma of grade 1-endometrial endometrioid carcinomas in cytology.

    The expression pattern of CD10 and CD31 identifies fine fibrovascular stroma of grade 1-endometrial endometrioid carcinomas in cytology.
    Norimatsu Y, Nishikawa T, Suzuki H, Hosokawa S, Yano H, Maeda Y, Kurokawa T, Shinagawa A, Kobayashi TK, Fulciniti F.

    04/23/2022
    Atomic Level Dissection of the Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) Homophilic Binding Interface: Implications for Endothelial Cell Barrier Function.

    Atomic Level Dissection of the Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) Homophilic Binding Interface: Implications for Endothelial Cell Barrier Function.
    Liao D, Sundlov J, Zhu J, Mei H, Hu Y, Newman DK, Newman PJ., Free PMC Article

    02/19/2022
    Characterization of CD31 expression in CD4+ and CD8+T cell subpopulations in chronic untreated HIV infection.

    Characterization of CD31 expression in CD4+ and CD8+T cell subpopulations in chronic untreated HIV infection.
    Briceño O, Peralta-Prado A, Garrido-Rodríguez D, Romero-Mora K, Chávez-Torres M, de la Barrera CA, Reyes-Terán G, Ávila-Ríos S.

    02/5/2022
    Rare PECAM1 variants in three families with lymphedema.

    Rare PECAM1 variants in three families with lymphedema.
    Michelini S, Amato B, Kenanoglu S, Veselenyiova D, Dautaj A, Kurti D, Baglivo M, Dundar M, Krajcovic J, Miggiano GA, Aquilanti B, Matera G, Velluti V, Gagliardi L, Basha SH, Bertelli M.

    12/25/2021
    Heparan sulfate proteoglycan glypican-1 and PECAM-1 cooperate in shear-induced endothelial nitric oxide production.

    Heparan sulfate proteoglycan glypican-1 and PECAM-1 cooperate in shear-induced endothelial nitric oxide production.
    Bartosch AMW, Mathews R, Mahmoud MM, Cancel LM, Haq ZS, Tarbell JM., Free PMC Article

    11/13/2021
    Serum CXCL13 and PECAM-1 can be used as diagnostic and prognostic markers in elderly patients with gastric cancer.

    Serum CXCL13 and PECAM-1 can be used as diagnostic and prognostic markers in elderly patients with gastric cancer.
    Li Y, Guo XB, Wei YH, Kang XL.

    08/28/2021
    Key microRNAs and hub genes associated with poor prognosis in lung adenocarcinoma.

    Key microRNAs and hub genes associated with poor prognosis in lung adenocarcinoma.
    Ye GC, Liu YF, Huang L, Zhang CY, Sheng YL, Wu B, Han L, Wu CL, Dong B, Qi Y., Free PMC Article

    08/21/2021
    Soluble platelet endothelial cell adhesion molecule 1 (sPECAM-1) improves diagnostic accuracy of D-Dimer in patients with suspected deep vein thrombosis (DVT).

    Soluble platelet endothelial cell adhesion molecule 1 (sPECAM-1) improves diagnostic accuracy of D-Dimer in patients with suspected deep vein thrombosis (DVT).
    Kellermair J, Fellner A, Bittinger A, Schneider S, Akbari K, Kammler J, Lambert T, Steinwender C., Free PMC Article

    06/12/2021
    CD31/PECAM-1 impacts engraftment, growth and spread of mantle cell lymphoma cells and positively correlates with extramedullary involvement.

    CD31/PECAM-1 impacts engraftment, growth and spread of mantle cell lymphoma cells and positively correlates with extramedullary involvement.
    Vockova P, Molinsky J, Klanova M, Karban J, Spacek M, Havranek O, Kupcova K, Kazantsev D, Trneny M, Klener P.

    05/8/2021
    CD31 (PECAM-1) Serves as the Endothelial Cell-Specific Receptor of Clostridium perfringens beta-Toxin.

    CD31 (PECAM-1) Serves as the Endothelial Cell-Specific Receptor of Clostridium perfringens β-Toxin.
    Bruggisser J, Tarek B, Wyder M, Müller P, von Ballmoos C, Witz G, Enzmann G, Deutsch U, Engelhardt B, Posthaus H.

    03/27/2021
    The exosome of platelet endothelial cell adhesion molecule-1 (PECAM1) protein: A potential risking star in high blood pressure patients (HBPP).

    The exosome of platelet endothelial cell adhesion molecule-1 (PECAM1) protein: A potential risking star in high blood pressure patients (HBPP).
    Zhu Z, Shen Y, Chen Y, Shi H, Shi Y., Free PMC Article

    02/13/2021
    Low shear stress induces endothelial cell apoptosis and monocyte adhesion by upregulating PECAM1 expression.

    Low shear stress induces endothelial cell apoptosis and monocyte adhesion by upregulating PECAM‑1 expression.
    Xie X, Wang F, Zhu L, Yang H, Pan D, Liu Y, Qu X, Gu Y, Li X, Chen S., Free PMC Article

    02/13/2021
    Increased circulating CD31+/CD42b-EMPs in Perthes disease and inhibit HUVECs angiogenesis via endothelial dysfunction.

    Increased circulating CD31+/CD42b-EMPs in Perthes disease and inhibit HUVECs angiogenesis via endothelial dysfunction.
    Li B, Huang Q, Lin C, Lu R, Wang T, Chen X, Liu Z, Liu Y, Wu J, Wu Y, Liao S, Ding X.

    02/6/2021
    Desmin and CD31 immunolabeling for detecting venous invasion of the pancreatobiliary tract cancers.

    Desmin and CD31 immunolabeling for detecting venous invasion of the pancreatobiliary tract cancers.
    Shin J, Wood LD, Hruban RH, Hong SM., Free PMC Article

    01/9/2021
    APC/Cdh1 targets PECAM-1 for ubiquitination and degradation in endothelial cells.

    APC/Cdh1 targets PECAM-1 for ubiquitination and degradation in endothelial cells.
    Liu J, Yao Q, Xiao L, Li F, Ma W, Zhang Z, Xie X, Yang C, Cui Q, Tian Y, Zhang C, Lai B, Wang N.

    12/19/2020
    PECAM-1 protects against DIC by dampening inflammatory responses via inhibiting macrophage pyroptosis and restoring vascular barrier integrity.

    PECAM-1 protects against DIC by dampening inflammatory responses via inhibiting macrophage pyroptosis and restoring vascular barrier integrity.
    Luo L, Xu M, Liao D, Deng J, Mei H, Hu Y.

    09/26/2020
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