| KLF13 restrains Dll4-muscular Notch2 axis to improve the muscle atrophy. | KLF13 restrains Dll4-muscular Notch2 axis to improve the muscle atrophy.
Yang S, Xiong L, Yang G, Xiang J, Li L, Kang L, Liang Z., Free PMC Article | 10/9/2024 |
| Kruppel-like factor 13 acts as a tumor suppressor in thyroid carcinoma by downregulating IFIT1. | Kruppel-like factor 13 acts as a tumor suppressor in thyroid carcinoma by downregulating IFIT1.
Liu Y, Song Y, He Y, Kong Z, Li H, Zhu Y, Liu S., Free PMC Article | 11/2/2023 |
| Kruppel-like Factors 3 Regulates Migration and Invasion of Gastric Cancer Cells Through NF-kappaB Pathway. | Kruppel-like Factors 3 Regulates Migration and Invasion of Gastric Cancer Cells Through NF-κB Pathway.
Liang X, Feng Z, Yan R, Liu F, Yin L, Shen H, Lu H, Zhang L. | 02/15/2023 |
| UC-BSCs Exosomes Regulate Th17/Treg Balance in Patients with Systemic Lupus Erythematosus via miR-19b/KLF13. | UC-BSCs Exosomes Regulate Th17/Treg Balance in Patients with Systemic Lupus Erythematosus via miR-19b/KLF13.
Tu J, Zheng N, Mao C, Liu S, Zhang H, Sun L., Free PMC Article | 01/11/2023 |
| KLF13 Loss-of-Function Mutations Underlying Familial Dilated Cardiomyopathy. | KLF13 Loss-of-Function Mutations Underlying Familial Dilated Cardiomyopathy.
Guo YH, Wang J, Guo XJ, Gao RF, Yang CX, Li L, Sun YM, Qiu XB, Xu YJ, Yang YQ., Free PMC Article | 11/19/2022 |
| The inhibitory effect of LINC00261 upregulation on the pancreatic cancer EMT process is mediated by KLF13 via the mTOR signaling pathway. | The inhibitory effect of LINC00261 upregulation on the pancreatic cancer EMT process is mediated by KLF13 via the mTOR signaling pathway.
Li B, Pang S, Dou J, Zhou C, Shen B, Zhou Y. | 05/21/2022 |
| KLF13 loss-of-function variation contributes to familial congenital heart defects. | KLF13 loss-of-function variation contributes to familial congenital heart defects.
Wang SS, Wang TM, Qiao XH, Huang RT, Xue S, Dong BB, Xu YJ, Liu XY, Yang YQ. | 07/3/2021 |
| Molecular Mechanisms for Kruppel-Like Factor 13 Actions in Hippocampal Neurons. | Molecular Mechanisms for Krüppel-Like Factor 13 Actions in Hippocampal Neurons.
Ávila-Mendoza J, Subramani A, Sifuentes CJ, Denver RJ. | 06/5/2021 |
| Our results show that the S156N and P163S variants may affect the transcriptional function of KLF13 and physical interaction with TBX5. These results identified KLF13 as a potential genetic risk factor for congenital heart disease. | Identification and analysis of KLF13 variants in patients with congenital heart disease.
Li W, Li B, Li T, Zhang E, Wang Q, Chen S, Sun K., Free PMC Article | 07/18/2020 |
| Results show that cg07814318 methylation in blood was significantly associated with obesity and correlated with several obesity-related physical and biochemical traits. The exome sequencing of KLF13 gene in blood identified nine SNPs within its gene body, and two SNPs as cis-meQTL of cg07814318. The sequencing variations within KLF13 genes could drive dynamic modifications of obesity-related CpG methylation. | Obesity-related CpG Methylation (cg07814318) of Kruppel-like Factor-13 (KLF13) Gene with Childhood Obesity and its cis-Methylation Quantitative Loci.
Koh IU, Lee HJ, Hwang JY, Choi NH, Lee S., Free PMC Article | 12/1/2018 |
| KLF13 functions as a tumor suppressor protein in PCa, and the pharmacological activation of KLF13 might represent a potential approach for the treatment of prostate cancer. | Transcription factor KLF13 inhibits AKT activation and suppresses the growth of prostate carcinoma cells.
Wang Q, Peng R, Wang B, Wang J, Yu W, Liu Y, Shi G., Free PMC Article | 10/20/2018 |
| Our results suggest the cg07814318 site could be involved in orexigenic processes, and also implicate KLF13 in obesity. Our findings are the first to associate methylation levels in blood with brain activity in obesity-related regions, and further support previous findings between ghrelin, brain activity and genetic differences. | A DNA methylation site within the KLF13 gene is associated with orexigenic processes based on neural responses and ghrelin levels.
Wiemerslage L, Islam R, van der Kamp C, Cao H, Olivo G, Ence-Eriksson F, Castillo S, Larsen AL, Bandstein M, Dahlberg LS, Perland E, Gustavsson V, Nilsson J, Vogel H, Schürmann A, Larsson EM, Rask-Andersen M, Benedict C, Schiöth HB. | 05/5/2018 |
| SLC44A1 and KLF13 may be involved in tumorigenesis and the metastasis of colon cancer by miRNA regulation | Integrated analysis of gene expression signatures associated with colon cancer from three datasets.
Gao P, He M, Zhang C, Geng C. | 04/14/2018 |
| KLF13 is critical for the activation of the HPV productive life cycle and is likely involved in initiation and progression of cervical cancer. | KLF13 regulates the differentiation-dependent human papillomavirus life cycle in keratinocytes through STAT5 and IL-8.
Zhang W, Hong S, Maniar KP, Cheng S, Jie C, Rademaker AW, Krensky AM, Clayberger C. | 09/9/2017 |
| Knockdown of either FBW7gamma or GSK3beta by small interfering RNA increases KLF13 expression in resting human T lymphocytes. | Fbw7γ-mediated degradation of KLF13 prevents RANTES expression in resting human but not murine T lymphocytes.
Kim DS, Zhang W, Millman SE, Hwang BJ, Kwon SJ, Clayberger C, Pagano M, Krensky AM., Free PMC Article | 11/3/2012 |
| No associations were found between maternal genetic polymorphisms in RANTES (-403G/A) and mother-to-child HIV-1 transmission; plasma, cervical and breastmilk viral loads; or breastmilk chemokine concentrations. | CCR5, RANTES and SDF-1 polymorphisms and mother-to-child HIV-1 transmission.
Katz DA, John-Stewart GC, Richardson BA, Majiwa M, Mabuka JM, Lohman-Payne B, Farquhar C., Free PMC Article | 11/27/2010 |
| KLF13 contributes to malignancy in oral cancer cells and may be a useful biomarker fo early detection and da possible target for therapy. | Overexpression of KLF13 and FGFR3 in oral cancer cells.
Henson BJ, Gollin SM., Free PMC Article | 07/12/2010 |
| Data support cross-regulation among BMP2, KLF9, and KLF13 to maintain progesterone sensitivity in stromal cells undergoing differentiation and suggest that loss of this network compromises establishment of uterine receptivity and implantation success. | Functional differentiation of uterine stromal cells involves cross-regulation between bone morphogenetic protein 2 and Kruppel-like factor (KLF) family members KLF9 and KLF13.
Pabona JM, Zeng Z, Simmen FA, Simmen RC., Free PMC Article | 07/12/2010 |
| Transient transfection of Kruppel-like factor 4 suppressed LDLR, steroidogenic acute regulatory protein, and CYP11A | Regulation of Kruppel-like factor 4, 9, and 13 genes and the steroidogenic genes LDLR, StAR, and CYP11A in ovarian granulosa cells.
Natesampillai S, Kerkvliet J, Leung PC, Veldhuis JD., Free PMC Article | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | Single nucleotide polymorphisms in the gene encoding Krüppel-like factor 7 are associated with type 2 diabetes.
Kanazawa A, Kawamura Y, Sekine A, Iida A, Tsunoda T, Kashiwagi A, Tanaka Y, Babazono T, Matsuda M, Kawai K, Iiizumi T, Fujioka T, Imanishi M, Kaku K, Iwamoto Y, Kawamori R, Kikkawa R, Nakamura Y, Maeda S. | 03/13/2008 |
| functional domains and DNA-binding sequences | Functional domains and DNA-binding sequences of RFLAT-1/KLF13, a Krüppel-like transcription factor of activated T lymphocytes.
Song A, Patel A, Thamatrakoln K, Liu C, Feng D, Clayberger C, Krensky AM. | 01/21/2010 |
| Coexpression of PRP4 and KLF13 increases nuclear localization of KLF13 and CCL5 transcription. | Interaction of PRP4 with Kruppel-like factor 13 regulates CCL5 transcription.
Huang B, Ahn YT, McPherson L, Clayberger C, Krensky AM., Free PMC Article | 01/21/2010 |
| protein analysis of BTEB3 and BTEB4 and their binding to CYP1A1 | Functional analysis of basic transcription element (BTE)-binding protein (BTEB) 3 and BTEB4, a novel Sp1-like protein, reveals a subfamily of transcriptional repressors for the BTE site of the cytochrome P4501A1 gene promoter.
Kaczynski JA, Conley AA, Fernandez Zapico M, Delgado SM, Zhang JS, Urrutia R., Free PMC Article | 01/21/2010 |
| KLF13 is a key regulator of late RANTES expression in T lymphocytes | Dynamic interplay of transcriptional machinery and chromatin regulates "late" expression of the chemokine RANTES in T lymphocytes.
Ahn YT, Huang B, McPherson L, Clayberger C, Krensky AM., Free PMC Article | 01/21/2010 |
| A translational rheostat for RFLAT-1 regulates RANTES expression in T lymphocytes. | A translational rheostat for RFLAT-1 regulates RANTES expression in T lymphocytes.
Nikolcheva T, Pyronnet S, Chou SY, Sonenberg N, Song A, Clayberger C, Krensky AM., Free PMC Article | 01/21/2010 |