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    PDGFB platelet derived growth factor subunit B [ Homo sapiens (human) ]

    Gene ID: 5155, updated on 18-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Role of endothelial PDGFB in arterio-venous malformations pathogenesis.

    Role of endothelial PDGFB in arterio-venous malformations pathogenesis.
    Lin Y, Gahn J, Banerjee K, Dobreva G, Singhal M, Dubrac A, Ola R., Free PMC Article

    05/6/2024
    Small vessel disease in primary familial brain calcification with novel truncating PDGFB variants.

    Small vessel disease in primary familial brain calcification with novel truncating PDGFB variants.
    Yektay Farahmand M, Wasselius J, Englund E, Braverman I, Puschmann A, Ilinca A.

    03/6/2024
    Platelet-derived growth factor subunit-B mediating the effect of dickkopf-1 on acute myocardial infarction risk: a two-step Mendelian randomization study.

    Platelet-derived growth factor subunit-B mediating the effect of dickkopf-1 on acute myocardial infarction risk: a two-step Mendelian randomization study.
    Li JS, Zheng PF, Rong JJ, Zheng ZF, Liu ZY, Wang CL., Free PMC Article

    01/29/2024
    Cancer-Associated Fibroblasts Promote Lymphatic Metastasis in Cholangiocarcinoma via the PDGF-BB/PDGFR-beta Mediated Paracrine Signaling Network.

    Cancer-Associated Fibroblasts Promote Lymphatic Metastasis in Cholangiocarcinoma via the PDGF-BB/PDGFR-β Mediated Paracrine Signaling Network.
    Yan J, Xiao G, Yang C, Liu Q, Lv C, Yu X, Zhou Z, Lin S, Bai Z, Lin H, Zhang R, Liu C., Free PMC Article

    01/26/2024
    JAM-A Overexpression in Human Umbilical Cord-Derived Mesenchymal Stem Cells Accelerated the Angiogenesis of Diabetic Wound By Enhancing Both Paracrine Function and Survival of Mesenchymal Stem Cells.

    JAM-A Overexpression in Human Umbilical Cord-Derived Mesenchymal Stem Cells Accelerated the Angiogenesis of Diabetic Wound By Enhancing Both Paracrine Function and Survival of Mesenchymal Stem Cells.
    Shu F, Lu J, Zhang W, Huang H, Lin J, Jiang L, Liu W, Liu T, Xiao S, Zheng Y, Xia Z.

    11/22/2023
    Preosteoclast plays a pathogenic role in syndesmophyte formation of ankylosing spondylitis through the secreted PDGFB - GRB2/ERK/RUNX2 pathway.

    Preosteoclast plays a pathogenic role in syndesmophyte formation of ankylosing spondylitis through the secreted PDGFB - GRB2/ERK/RUNX2 pathway.
    Tang Y, Yang K, Liu Q, Ma Y, Zhu H, Tang K, Geng C, Xie J, Zhuo D, Wu W, Jin L, Xiao W, Wang J, Zhu Q, Liu J., Free PMC Article

    10/12/2023
    Platelet-Derived Growth Factor B Is a Key Element in the Pathological Bone Formation of Ankylosing Spondylitis.

    Platelet-Derived Growth Factor B Is a Key Element in the Pathological Bone Formation of Ankylosing Spondylitis.
    Jo S, Lee SH, Park J, Nam B, Kim H, Youn J, Lee S, Kim TJ, Sung IH, Choi SH, Park YS, Inman RD, Kim TH.

    02/13/2023
    The Role of Platelet-Derived Growth Factor in Focal Segmental Glomerulosclerosis.

    The Role of Platelet-Derived Growth Factor in Focal Segmental Glomerulosclerosis.
    Jia T, Xu T, Smeets B, Buhl EM, Moeller MJ, Floege J, Klinkhammer BM, Boor P., Free PMC Article

    02/11/2023
    Primary familial brain calcification with mild phenotype due to a new PDGFB mutation.

    Primary familial brain calcification with mild phenotype due to a new PDGFB mutation.
    Locci S, Bianchi S, De Stefano N, Mignarri A.

    10/29/2022
    Living with primary brain calcification with PDGFB variants: A qualitative study.

    Living with primary brain calcification with PDGFB variants: A qualitative study.
    Takeuchi T, Aoyagi H, Kuwako Y, Hozumi I., Free PMC Article

    10/15/2022
    Role of TGF-beta1 and PDGF-B in Crimean-Congo hemorrhagic fever in Eastern Anatolia Region in Turkey.

    Role of TGF-β1 and PDGF-B in Crimean-Congo hemorrhagic fever in Eastern Anatolia Region in Turkey.
    Cinislioglu N, Özkan HI, Aşkın S, Yılmaz S, Kızıltunç A, Özden K.

    10/1/2022
    Platelet-derived growth factor BB is reduced in endometrial endothelial cells of women with abnormal uterine bleeding-endometrial disorder.

    Platelet-derived growth factor BB is reduced in endometrial endothelial cells of women with abnormal uterine bleeding-endometrial disorder.
    Biswas Shivhare S, Lu Q, Sun D, Hou H, Bulmer JN, Innes BA, Hapangama DK, Lash GE.

    09/17/2022
    Intratumoral PDGFB gene predominantly expressed in endothelial cells is associated with angiogenesis and lymphangiogenesis, but not with metastasis in breast cancer.

    Intratumoral PDGFB gene predominantly expressed in endothelial cells is associated with angiogenesis and lymphangiogenesis, but not with metastasis in breast cancer.
    Wu R, Gandhi S, Tokumaru Y, Asaoka M, Oshi M, Yan L, Ishikawa T, Takabe K.

    08/13/2022
    Diverse roles of tumor-stromal PDGFB-to-PDGFRbeta signaling in breast cancer growth and metastasis.

    Diverse roles of tumor-stromal PDGFB-to-PDGFRβ signaling in breast cancer growth and metastasis.
    Shah S, Sizemore GM.

    05/14/2022
    Circulating exosomal miR-363-5p inhibits lymph node metastasis by downregulating PDGFB and serves as a potential noninvasive biomarker for breast cancer.

    Circulating exosomal miR-363-5p inhibits lymph node metastasis by downregulating PDGFB and serves as a potential noninvasive biomarker for breast cancer.
    Wang X, Qian T, Bao S, Zhao H, Chen H, Xing Z, Li Y, Zhang M, Meng X, Wang C, Wang J, Gao H, Liu J, Zhou M, Wang X., Free PMC Article

    04/2/2022
    MiR-18a Inhibits PI3K/AKT Signaling Pathway to Regulate PDGF BB-Induced Airway Smooth Muscle Cell Proliferation and Phenotypic Transformation.

    MiR-18a Inhibits PI3K/AKT Signaling Pathway to Regulate PDGF BB-Induced Airway Smooth Muscle Cell Proliferation and Phenotypic Transformation.
    Yang W, Chen Y, Huang C, Wang W, Huang C, Li Y., Free PMC Article

    03/5/2022
    High tumor cell platelet-derived growth factor receptor beta expression is associated with shorter survival in malignant pleural epithelioid mesothelioma.

    High tumor cell platelet-derived growth factor receptor beta expression is associated with shorter survival in malignant pleural epithelioid mesothelioma.
    Ollila H, Paajanen J, Wolff H, Ilonen I, Sutinen E, Välimäki K, Östman A, Anttila S, Kettunen E, Räsänen J, Kallioniemi O, Myllärniemi M, Mäyränpää MI, Pellinen T., Free PMC Article

    02/19/2022
    Lyophilised Platelet-Rich Fibrin: Physical and Biological Characterisation.

    Lyophilised Platelet-Rich Fibrin: Physical and Biological Characterisation.
    Ngah NA, Dias GJ, Tong DC, Mohd Noor SNF, Ratnayake J, Cooper PR, Hussaini HM., Free PMC Article

    02/12/2022
    Anoikis resistant gastric cancer cells promote angiogenesis and peritoneal metastasis through C/EBPbeta-mediated PDGFB autocrine and paracrine signaling.

    Anoikis resistant gastric cancer cells promote angiogenesis and peritoneal metastasis through C/EBPβ-mediated PDGFB autocrine and paracrine signaling.
    Du S, Yang Z, Lu X, Yousuf S, Zhao M, Li W, Miao J, Wang X, Yu H, Zhu X, Chen H, Shi L, Xu E, Xia X, Guan W.

    01/1/2022
    Endothelial cell-derived pro-fibrotic factors increase TGF-beta1 expression by smooth muscle cells in response to cycles of hypoxia-hyperoxia.

    Endothelial cell-derived pro-fibrotic factors increase TGF-β1 expression by smooth muscle cells in response to cycles of hypoxia-hyperoxia.
    Ismaeel A, Miserlis D, Papoutsi E, Haynatzki G, Bohannon WT, Smith RS, Eidson JL, Casale GP, Pipinos II, Koutakis P., Free PMC Article

    01/1/2022
    Determination of COL1A1-PDGFB breakpoints by next-generation sequencing in the molecular diagnosis of dermatofibrosarcoma protuberans.

    Determination of COL1A1-PDGFB breakpoints by next-generation sequencing in the molecular diagnosis of dermatofibrosarcoma protuberans.
    Zhu R, Yan J, Li B, Tan F, Yan W, Shen J, Fan L, Ding L, Chen Y, Tang Y, Liu Y, Bai Y.

    12/25/2021
    Measurement of 45 cytokine, chemokine and growth factors in established cell culture supernatants and autologous serum from advanced melanoma patients.

    Measurement of 45 cytokine, chemokine and growth factors in established cell culture supernatants and autologous serum from advanced melanoma patients.
    Montoyo-Pujol YG, Wang X, Bermúdez-Sánchez S, Martin A, Almazan F, López-Nevot MÁ.

    10/2/2021
    Why PRP works only on certain patients with tennis elbow? Is PDGFB gene a key for PRP therapy effectiveness? A prospective cohort study.

    Why PRP works only on certain patients with tennis elbow? Is PDGFB gene a key for PRP therapy effectiveness? A prospective cohort study.
    Niemiec P, Szyluk K, Balcerzyk A, Kalita M, Jarosz A, Iwanicka J, Iwanicki T, Nowak T, Negru M, Francuz T, Garczorz W, Grzeszczak W, Górczyńska-Kosiorz S, Kania W, Żak I., Free PMC Article

    09/25/2021
    Plateletderived growth factorBB mediates pancreatic cancer malignancy via regulation of the Hippo/Yesassociated protein signaling pathway.

    Platelet‑derived growth factor‑BB mediates pancreatic cancer malignancy via regulation of the Hippo/Yes‑associated protein signaling pathway.
    Li T, Guo T, Liu H, Jiang H, Wang Y., Free PMC Article

    09/25/2021
    MicroRNA-432-5p regulates sprouting and intussusceptive angiogenesis in osteosarcoma microenvironment by targeting PDGFB.

    MicroRNA-432-5p regulates sprouting and intussusceptive angiogenesis in osteosarcoma microenvironment by targeting PDGFB.
    Vimalraj S, Subramanian R, Saravanan S, Arumugam B, Anuradha D.

    09/4/2021
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