| Up-regulation of lncRNA WT1-AS ameliorates Abeta-stimulated neuronal injury through modulation of miR-186-5p/CCND2 axis in Alzheimer's disease. | Up-regulation of lncRNA WT1-AS ameliorates Aβ-stimulated neuronal injury through modulation of miR-186-5p/CCND2 axis in Alzheimer's disease.
Tang Y, Zhang X, Wang S, Liu L, Wang Q, Liu Y, Yu Y, Zhai Q. | 03/21/2024 |
| Overexpression of long non-coding RNA WT1-AS or silencing of PIK3AP1 are inhibitory to cervical cancer progression. | Overexpression of long non-coding RNA WT1-AS or silencing of PIK3AP1 are inhibitory to cervical cancer progression.
Tong W, Zhang H., Free PMC Article | 04/23/2022 |
| WT1-AS/IGF2BP2 Axis Is a Potential Diagnostic and Prognostic Biomarker for Lung Adenocarcinoma According to ceRNA Network Comprehensive Analysis Combined with Experiments. | WT1-AS/IGF2BP2 Axis Is a Potential Diagnostic and Prognostic Biomarker for Lung Adenocarcinoma According to ceRNA Network Comprehensive Analysis Combined with Experiments.
Jia M, Shi Y, Xie Y, Li W, Deng J, Fu D, Bai J, Ma Y, Zuberi Z, Li J, Li Z., Free PMC Article | 02/26/2022 |
| Unravelling the Role of LncRNA WT1-AS/miR-206/NAMPT Axis as Prognostic Biomarkers in Lung Adenocarcinoma. | Unravelling the Role of LncRNA WT1-AS/miR-206/NAMPT Axis as Prognostic Biomarkers in Lung Adenocarcinoma.
Li W, Liu Y, Li ZJ, Shi Y, Deng J, Bai J, Ma L, Zeng XX, Feng SS, Ren JL, Luo FJ, Rong DY, Chen XQ, Yin HQ, Chen Z, Da F., Free PMC Article | 07/24/2021 |
| LncRNA WT1-AS downregulates lncRNA UCA1 to suppress non-small cell lung cancer and predicts poor survival. | LncRNA WT1-AS downregulates lncRNA UCA1 to suppress non-small cell lung cancer and predicts poor survival.
Wan Y, Yao D, Fang F, Wang Y, Wu G, Qian Y., Free PMC Article | 05/15/2021 |
| LncRNA WT1-AS over-expression inhibits non-small cell lung cancer cell stemness by down-regulating TGF-beta1. | LncRNA WT1-AS over-expression inhibits non-small cell lung cancer cell stemness by down-regulating TGF-β1.
Jiang X, Wang J, Fang L., Free PMC Article | 02/2/2021 |
| Long Noncoding RNA WT1-AS Inhibit Cell Malignancy via miR-494-3p in Glioma. | Long Noncoding RNA WT1-AS Inhibit Cell Malignancy via miR-494-3p in Glioma.
Qiu G, Tong W, Jiang C, Xie Q, Zou J, Luo C, Zhao J, Zhang L, Zhao J., Free PMC Article | 11/21/2020 |
| Long non-coding RNA WT1-AS inhibits cell aggressiveness via miR-203a-5p/FOXN2 axis and is associated with prognosis in cervical cancer. | Long non-coding RNA WT1-AS inhibits cell aggressiveness via miR-203a-5p/FOXN2 axis and is associated with prognosis in cervical cancer.
Dai SG, Guo LL, Xia X, Pan Y. | 08/15/2020 |
| WT1-AS overexpression caused inhibited migration and invasion of TNBC cells. TGF-beta1 overexpression showed opposite functions and reduced the effects of WT1-AS overexpression. WT1-AS may downregulate TGF-beta to inhibit the migration and invasion of TNBC cells. | LncRNA WT1-AS Inhibits Triple-Negative Breast Cancer Cell Migration and Invasion by Downregulating Transforming Growth Factor β1.
Wang J, Xi C, Yang X, Lu X, Yu K, Zhang Y, Gao R. | 04/11/2020 |
| Tumor protein p53 (P53) was down-regulated in cervical squamous cell carcinoma (CSCC) tissues and positively correlated with LncRNA WT1-AS. WT1-AS. | LncRNA WT1-AS up-regulates p53 to inhibit the proliferation of cervical squamous carcinoma cells.
Zhang Y, Na R, Wang X., Free PMC Article | 04/4/2020 |
| WT1-AS expression was significantly down-regulated in tumor tissues compared to matched adjacent non-tumor tissues. The WT1-AS expression level was also associated with tumor size and the clinicopathological stage. Cell proliferation, migration, and invasion were inhibited, and the proportion of G0/G1 cells increased when WT1-AS was ectopically-expressed in gastric cancer cells. | Decreased expression of long non-coding RNA WT1-AS promotes cell proliferation and invasion in gastric cancer.
Du T, Zhang B, Zhang S, Jiang X, Zheng P, Li J, Yan M, Zhu Z, Liu B. | 01/26/2019 |
| WT1-AS downregulates WT1 expression in hepatocellular carcinoma tumors and promotes apoptosis by binding to the promoter region of WT1. WT1-AS may function as a tumor suppressor in hepatocellular carcinoma by reversing the oncogenic effects of WT1. | WT1-AS promotes cell apoptosis in hepatocellular carcinoma through down-regulating of WT1.
Lv L, Chen G, Zhou J, Li J, Gong J., Free PMC Article | 07/2/2016 |
| Data suggest that WT1-as, MEG3 and ANRIL could potentially be used as new primary myelofibrosis (PMF) diagnostic biomarkers with prognostic implications. | Abnormal expression patterns of WT1-as, MEG3 and ANRIL long non-coding RNAs in CD34+ cells from patients with primary myelofibrosis and their clinical correlations.
Pennucci V, Zini R, Norfo R, Guglielmelli P, Bianchi E, Salati S, Sacchi G, Prudente Z, Tenedini E, Ruberti S, Paoli C, Fanelli T, Mannarelli C, Tagliafico E, Ferrari S, Vannucchi AM, Manfredini R, Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative (AGIMM) Investigators. | 04/9/2016 |
| WT1 and WT1AS (WT1 antisense RNA) genes are imprinted in human kidney, with preferential expression from the paternal allele, and imprinting defects at chromosome 11p13 may contribute to Wilms' tumourigenesis. | A CTCF-binding silencer regulates the imprinted genes AWT1 and WT1-AS and exhibits sequential epigenetic defects during Wilms' tumourigenesis.
Hancock AL, Brown KW, Moorwood K, Moon H, Holmgren C, Mardikar SH, Dallosso AR, Klenova E, Loukinov D, Ohlsson R, Lobanenkov VV, Malik K. | 10/29/2010 |
| Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | Variants in the Wilms' tumor gene are associated with focal segmental glomerulosclerosis in the African American population.
Orloff MS, Iyengar SK, Winkler CA, Goddard KA, Dart RA, Ahuja TS, Mokrzycki M, Briggs WA, Korbet SM, Kimmel PL, Simon EE, Trachtman H, Vlahov D, Michel DM, Berns JS, Smith MC, Schelling JR, Sedor JR, Kopp JB. | 03/13/2008 |