| microRNA-92b-3p augments colon cancer development through inhibiting KLF3. | microRNA-92b-3p augments colon cancer development through inhibiting KLF3.
Liu X, Zhang L. | 12/20/2023 |
| Molecular Expression and Prognostic Implications of Kruppel-Like Factor 3 (KLF3) in Clear Cell Renal Cell Carcinoma. | Molecular Expression and Prognostic Implications of Krüppel-Like Factor 3 (KLF3) in Clear Cell Renal Cell Carcinoma.
Wan B, Zhang W, Deng X, Lu Y, Zhang Z, Yang Y. | 12/20/2023 |
| Decreased KLF3 Expression via miR-660-5p Targeting Suppresses Gastric Cancer Cell Progression. | Decreased KLF3 Expression via miR-660-5p Targeting Suppresses Gastric Cancer Cell Progression.
Yu W, Shen J, Wang X, Qin H, Xing C. | 11/15/2023 |
| Pan-cancer analysis of Kruppel-like factor 3 and its carcinogenesis in pancreatic cancer. | Pan-cancer analysis of Krüppel-like factor 3 and its carcinogenesis in pancreatic cancer.
Zhu J, Teng H, Zhu X, Yuan J, Zhang Q, Zou Y., Free PMC Article | 08/22/2023 |
| KLF3 Transcription Activates WNT1 and Promotes the Growth and Metastasis of Gastric Cancer via Activation of the WNT/beta-Catenin Signaling Pathway. | KLF3 Transcription Activates WNT1 and Promotes the Growth and Metastasis of Gastric Cancer via Activation of the WNT/β-Catenin Signaling Pathway.
Li Y, Wang Y, Zou Q, Li S, Zhang F. | 06/29/2023 |
| microRNA-21-5p from M2 macrophage-derived extracellular vesicles promotes the differentiation and activity of pancreatic cancer stem cells by mediating KLF3. | microRNA-21-5p from M2 macrophage-derived extracellular vesicles promotes the differentiation and activity of pancreatic cancer stem cells by mediating KLF3.
Chang J, Li H, Zhu Z, Mei P, Hu W, Xiong X, Tao J., Free PMC Article | 08/6/2022 |
| Hepatic Meteorin-like and Kruppel-like Factor 3 are Associated with Weight Loss and Liver Injury. | Hepatic Meteorin-like and Krüppel-like Factor 3 are Associated with Weight Loss and Liver Injury.
Grander C, Grabherr F, Enrich B, Meyer M, Mayr L, Schwärzler J, Pedrini A, Effenberger M, Adolph TE, Tilg H. | 06/25/2022 |
| Bone mesenchymal stem cells (BMSCs)-derived exosomal microRNA-21-5p regulates Kruppel-like factor 3 (KLF3) to promote osteoblast proliferation in vitro. | Bone mesenchymal stem cells (BMSCs)-derived exosomal microRNA-21-5p regulates Kruppel-like factor 3 (KLF3) to promote osteoblast proliferation in vitro.
You M, Ai Z, Zeng J, Fu Y, Zhang L, Wu X., Free PMC Article | 06/11/2022 |
| Exosome miR-23a-3p from Osteoblast Alleviates Spinal Cord Ischemia/Reperfusion Injury by Down-Regulating KLF3-Activated CCNL2 Transcription. | Exosome miR-23a-3p from Osteoblast Alleviates Spinal Cord Ischemia/Reperfusion Injury by Down-Regulating KLF3-Activated CCNL2 Transcription.
Wu C, Zhu Q, Yao Y, Shi Z, Jin C, Chen L. | 05/21/2022 |
| Fat mass and obesity associated (FTO)-mediated N6-methyladenosine modification of Kruppel-like factor 3 (KLF3) promotes osteosarcoma progression. | Fat mass and obesity associated (FTO)-mediated N6-methyladenosine modification of Krüppel-like factor 3 (KLF3) promotes osteosarcoma progression.
Shan HJ, Gu WX, Duan G, Chen HL., Free PMC Article | 05/7/2022 |
| Unravelling Structure, Localization, and Genetic Crosstalk of KLF3 in Human Breast Cancer. | Unravelling Structure, Localization, and Genetic Crosstalk of KLF3 in Human Breast Cancer.
Khan K, Safi S, Abbas A, Badshah Y, Dilshad E, Rafiq M, Zahra K, Shabbir M., Free PMC Article | 05/22/2021 |
| Expression of human Kruppel-like factor 3 in peripheral blood as a promising biomarker for acute leukemia. | Expression of human Krüppel-like factor 3 in peripheral blood as a promising biomarker for acute leukemia.
Yan M, Liu H, Xu J, Cen X, Wang Q, Xu W, Wang W, Qiu Z, Ou J, Dong Y, Zhu P, Ren H, He F, Wang M., Free PMC Article | 05/15/2021 |
| LncRNA NEAT1/miR-1224/KLF3 contributes to cell proliferation, apoptosis and invasion in lung cancer. | LncRNA NEAT1/miR-1224/KLF3 contributes to cell proliferation, apoptosis and invasion in lung cancer.
Yu PF, Wang Y, Lv W, Kou D, Hu HL, Guo SS, Zhao YJ. | 12/19/2020 |
| bioinformatics analysis and in vitro experiments indicated that the role of KLF3 in lung cancer metastasis is dependent on the STAT3 signaling pathway. Overall, our data indicated the crucial function of KLF3 in lung cancer metastasis and suggested opportunities to improve the therapy of patients with lung cancer. | KLF3 is a crucial regulator of metastasis by controlling STAT3 expression in lung cancer.
Sun W, Hu S, Zu Y, Deng Y., Free PMC Article | 01/25/2020 |
| These data demonstrate that miR-326/Sp1/KLF3 regulatory axis is involved in the development of lung cancer. miR-326 could bind to 3'UTR of Sp1 but not KLF3 and decreased the accumulation of Sp1, which further indirectly reduced KLF3 expression and inactivated JAK2/STAT3 and PI3K/AKT signaling pathways in vitro and in vivo. | MiR-326/Sp1/KLF3: A novel regulatory axis in lung cancer progression.
Wang R, Xu J, Xu J, Zhu W, Qiu T, Li J, Zhang M, Wang Q, Xu T, Guo R, Lu K, Yin Y, Gu Y, Zhu L, Huang P, Liu P, Liu L, De W, Shu Y., Free PMC Article | 04/20/2019 |
| Low KLF3 expression is associated with colorectal cancer. | RNA sequencing analysis reveals protective role of kruppel-like factor 3 in colorectal cancer.
Wang X, Jiang Z, Zhang Y, Wang X, Liu L, Fan Z., Free PMC Article | 10/14/2017 |
| Among the mechanosensitive genes, the two transcription factors, HoxA5 and Klf3, contain cAMP-response-elements methylation of which could serve as a mechanosensitive master switch in gene expression in atherosclerosis. (Review) | The role of epigenetics in the endothelial cell shear stress response and atherosclerosis.
Dunn J, Simmons R, Thabet S, Jo H., Free PMC Article | 06/11/2016 |
| Klf-3 expression is downregulated in human metastatic sarcomas, and Klf-3 levels negatively correlate with miR-182 expression. | Epigenetic silencing of Kruppel like factor-3 increases expression of pro-metastatic miR-182.
Sachdeva M, Dodd RD, Huang Z, Grenier C, Ma Y, Lev DC, Cardona DM, Murphy SK, Kirsch DG., Free PMC Article | 02/6/2016 |
| A feedback loop consisting of microRNA 23a/27a and the beta-like globin suppressors KLF3 and SP1 regulates globin gene expression. | A feedback loop consisting of microRNA 23a/27a and the β-like globin suppressors KLF3 and SP1 regulates globin gene expression.
Ma Y, Wang B, Jiang F, Wang D, Liu H, Yan Y, Dong H, Wang F, Gong B, Zhu Y, Dong L, Yin H, Zhang Z, Zhao H, Wu Z, Zhang J, Zhou J, Yu J., Free PMC Article | 11/30/2013 |
| B cell differentiation is significantly impaired in the bone marrow, spleen, and peritoneal cavity of Klf3 null mice; the defects are cell autonomous. | Impaired B cell development in the absence of Krüppel-like factor 3.
Vu TT, Gatto D, Turner V, Funnell AP, Mak KS, Norton LJ, Kaplan W, Cowley MJ, Agenès F, Kirberg J, Brink R, Pearson RC, Crossley M. | 01/14/2012 |
| Low KLF3 is associated with acute myeloid leukemia. | Deregulated expression of Kruppel-like factors in acute myeloid leukemia.
Humbert M, Halter V, Shan D, Laedrach J, Leibundgut EO, Baerlocher GM, Tobler A, Fey MF, Tschan MP. | 08/20/2011 |
| KLF3 is an important regulator of several biological processes, including adipogenesis, erythropoiesis, and B cell development. (Review) | The mammalian zinc finger transcription factor Krüppel-like factor 3 (KLF3/BKLF).
Pearson RC, Funnell AP, Crossley M. | 06/25/2011 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators., Free PMC Article | 09/15/2010 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesGene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium. Single nucleotide polymorphisms in the gene encoding Krüppel-like factor 7 are associated with type 2 diabetes.
Kanazawa A, Kawamura Y, Sekine A, Iida A, Tsunoda T, Kashiwagi A, Tanaka Y, Babazono T, Matsuda M, Kawai K, Iiizumi T, Fujioka T, Imanishi M, Kaku K, Iwamoto Y, Kawamori R, Kikkawa R, Nakamura Y, Maeda S. | 03/13/2008 |