| Novel compound heterozygous MYO15A splicing variants in autosomal recessive non-syndromic hearing loss. | Novel compound heterozygous MYO15A splicing variants in autosomal recessive non-syndromic hearing loss.
Zheng K, Lin S, Gao J, Chen S, Su J, Liu Z, Duan S., Free PMC Article | 01/5/2024 |
| Loss-of-function mutations in MYO15A and OTOF cause non-syndromic hearing loss in two Yemeni families. | Loss-of-function mutations in MYO15A and OTOF cause non-syndromic hearing loss in two Yemeni families.
Asaad M, Mahfood M, Al Mutery A, Tlili A., Free PMC Article | 05/17/2023 |
| Identification of novel compound heterozygous mutations of the MYO15A gene with autosomal recessive non-syndromic hearing loss. | Identification of novel compound heterozygous mutations of the MYO15A gene with autosomal recessive non-syndromic hearing loss.
Wang L, Zhang Y, Xue Q, Huang P, Liu X., Free PMC Article | 10/15/2022 |
| Exosomal microRNA-1 and MYO15A as a target for therapy and diagnosis in renal cell carcinoma. | Exosomal microRNA-1 and MYO15A as a target for therapy and diagnosis in renal cell carcinoma.
Yoshino H, Tatarano S, Tamai M, Tsuruda M, Iizasa S, Arima J, Kawakami I, Fukumoto W, Kawahara I, Li G, Sakaguchi T, Inoguchi S, Yamada Y, Enokida H. | 10/15/2022 |
| Hearing Features and Cochlear Implantation Outcomes in Patients With Pathogenic MYO15A Variants: a Multicenter Observational Study. | Hearing Features and Cochlear Implantation Outcomes in Patients With Pathogenic MYO15A Variants: a Multicenter Observational Study.
Chen PY, Tsai CY, Wu JL, Li YL, Wu CM, Chen KC, Hwang CF, Wu HP, Lin HC, Cheng YF, Lo MY, Liu TC, Yang TH, Chen PL, Hsu CJ, Wu CC. | 06/25/2022 |
| Analysis of the genotype-phenotype correlation of MYO15A variants in Chinese non-syndromic hearing loss patients. | Analysis of the genotype-phenotype correlation of MYO15A variants in Chinese non-syndromic hearing loss patients.
Fu Y, Huang S, Gao X, Han M, Wang G, Kang D, Yuan Y, Dai P., Free PMC Article | 04/16/2022 |
| Whole-Exome Sequencing Identifies a Recurrent Small In-Frame Deletion in MYO15A Causing Autosomal Recessive Nonsyndromic Hearing Loss in 3 Iranian Pedigrees. | Whole-Exome Sequencing Identifies a Recurrent Small In-Frame Deletion in MYO15A Causing Autosomal Recessive Nonsyndromic Hearing Loss in 3 Iranian Pedigrees.
Nasrniya S, Miar P, Narrei S, Sepehrnejad M, Nilforoush MH, Abtahi H, Tabatabaiefar MA. | 03/12/2022 |
| Heterogeneity of MYO15A variants significantly determine the feasibility of acoustic stimulation with hearing aid and cochlear implant. | Heterogeneity of MYO15A variants significantly determine the feasibility of acoustic stimulation with hearing aid and cochlear implant.
Na G, Choi HJ, Joo SY, Rim JH, Kim JA, Kim HY, Yu S, Jeong Y, Shin GC, Noh HE, Lee HY, Kim DH, Gee HY, Jung J, Choi JY. | 02/5/2022 |
| A synonymous variant in MYO15A enriched in the Ashkenazi Jewish population causes autosomal recessive hearing loss due to abnormal splicing. | A synonymous variant in MYO15A enriched in the Ashkenazi Jewish population causes autosomal recessive hearing loss due to abnormal splicing.
Hirsch Y, Tangshewinsirikul C, Booth KT, Azaiez H, Yefet D, Quint A, Weiden T, Brownstein Z, Macarov M, Davidov B, Pappas J, Rabin R, Kenna MA, Oza AM, Lafferty K, Amr SS, Rehm HL, Kolbe DL, Frees K, Nishimura C, Luo M, Farra C, Morton CC, Scher SY, Ekstein J, Avraham KB, Smith RJH, Shen J., Free PMC Article | 02/5/2022 |
| PNPT1, MYO15A, PTPRQ, and SLC12A2-associated genetic and phenotypic heterogeneity among hearing impaired assortative mating families in Southern India. | PNPT1, MYO15A, PTPRQ, and SLC12A2-associated genetic and phenotypic heterogeneity among hearing impaired assortative mating families in Southern India.
Vanniya S P, Chandru J, Jeffrey JM, Rabinowitz T, Brownstein Z, Krishnamoorthy M, Avraham KB, Cheng L, Shomron N, Srisailapathy CRS. | 01/29/2022 |
| Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex. | Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex.
Lin L, Shi Y, Wang M, Wang C, Lu Q, Zhu J, Zhang R. | 01/29/2022 |
| Identification of Novel Compound Heterozygous MYO15A Mutations in Two Chinese Families with Autosomal Recessive Nonsyndromic Hearing Loss. | Identification of Novel Compound Heterozygous MYO15A Mutations in Two Chinese Families with Autosomal Recessive Nonsyndromic Hearing Loss.
Wang XH, Xie L, Chen S, Xu K, Bai X, Jin Y, Qiu Y, Liu XZ, Sun Y, Kong WJ., Free PMC Article | 12/11/2021 |
| Whole exome sequencing reveals pathogenic variants in MYO3A, MYO15A and COL9A3 and differential frequencies in ancestral alleles in hearing impairment genes among individuals from Cameroon. | Whole exome sequencing reveals pathogenic variants in MYO3A, MYO15A and COL9A3 and differential frequencies in ancestral alleles in hearing impairment genes among individuals from Cameroon.
Wonkam A, Manyisa N, Bope CD, Dandara C, Chimusa ER., Free PMC Article | 10/2/2021 |
| The ATPase mechanism of myosin 15, the molecular motor mutated in DFNB3 human deafness. | The ATPase mechanism of myosin 15, the molecular motor mutated in DFNB3 human deafness.
Jiang F, Takagi Y, Shams A, Heissler SM, Friedman TB, Sellers JR, Bird JE., Free PMC Article | 08/28/2021 |
| Compound Heterozygous Mutations in TMC1 and MYO15A Are Associated with Autosomal Recessive Nonsyndromic Hearing Loss in Two Chinese Han Families. | Compound Heterozygous Mutations in TMC1 and MYO15A Are Associated with Autosomal Recessive Nonsyndromic Hearing Loss in Two Chinese Han Families.
Xu P, Xu J, Peng H, Yang T., Free PMC Article | 06/26/2021 |
| Investigation of MYO15A and MYO7A Mutations in Iranian Patients with Nonsyndromic Hearing Loss. | Investigation of MYO15A and MYO7A Mutations in Iranian Patients with Nonsyndromic Hearing Loss.
Farjami M, Fathi M, Ghasemi MM, Rajati M, Eslahi A, Alimardani M, Mojarrad M. | 05/8/2021 |
| Novel MYO15A variants are associated with hearing loss in the two Iranian pedigrees. | Novel MYO15A variants are associated with hearing loss in the two Iranian pedigrees.
Khatami S, Askari M, Bahreini F, Hashemzadeh-Chaleshtori M, Hematian S, Asgharzade S., Free PMC Article | 01/9/2021 |
| [Analysis of MYO15A variation in children with DFNB3]. | [Analysis of MYO15A variation in children with DFNB3].
Ren SM, Wu QH, Jiao ZH, Chen YB, Chen C, Kong XD, Qin ZB. | 12/5/2020 |
| Novel compound heterozygosity at the MYO15A including an duplication variant c.3866dupC, p.His1290Alafs*25 and a 3-bp deletion (c.10251_10253del, p.Phe3420del), resulting in protein length changes and premature protein truncation, respectively, was found in Chinese family with non-syndromic hearing loss. | Identification of novel variants in MYO15A, OTOF, and RDX with hearing loss by next-generation sequencing.
Bai X, Nian S, Feng L, Ruan Q, Luo X, Wu M, Yan Z., Free PMC Article | 07/4/2020 |
| The allele frequencies of mutations in deafness genes in the Taiwanese families are shown. The most prevalent pathogenic variants included GJB2 mutations (22.92%), SLC26A4 mutations (6.03%), OTOF mutations (4.62%), MYO15A mutations (2.98%), and the m.1555A>G mutation (1.95%). | Genetic Epidemiology and Clinical Features of Hereditary Hearing Impairment in the Taiwanese Population.
Wu CC, Tsai CY, Lin YH, Chen PY, Lin PH, Cheng YF, Wu CM, Lin YH, Lee CY, Erdenechuluun J, Liu TC, Chen PL, Hsu CJ., Free PMC Article | 03/21/2020 |
| A novel MITF mutation along with a previously described MYO15A mutation segregate with an autosomal recessive non-syndromic Hearing loss (HL) case with a post-lingual onset. The findings highlight the importance of carrying whole exome sequencing for a comprehensive assessment of HL genetic heterogeneity | Post-lingual non-syndromic hearing loss phenotype: a polygenic case with 2 biallelic mutations in MYO15A and MITF.
Khalil A, Karroum SB, Barake R, Dunya G, Abou-Rizk S, Kamar A, Nemer G, Bassim M., Free PMC Article | 03/7/2020 |
| A novel nonsense variant of MYO15A was discovered in a consanguineous Iranian family with sensorineural deafness. | Identification and Clinical Implications of a Novel MYO15A Variant in a Consanguineous Iranian Family by Targeted Exome Sequencing.
Zarepour N, Koohiyan M, Taghipour-Sheshdeh A, Nemati-Zargaran F, Saki N, Mohammadi-Asl J, Tabatabaiefar MA, Hashemzadeh-Chaleshtori M. | 02/22/2020 |
| Identified a novel homozygous mutation p.R3191C in MYO15A gene causing deafness in Kuzakh family. | Identification of a novel homozygous mutation in the MYO15A gene in a Kazakh family with non-syndromic hearing loss.
Zhou H, Kuermanhan A, Zhang Z, Wang W, Dong J, Zhou Z, Mu J, Zhao L, Wang J, Li B, Chen B. | 01/4/2020 |
| work extended the MYO15A variant spectrum, enriched our knowledge of auditory phenotypes, and tried to explore the genotype-phenotype correlation in different populations in order to investigate the cause of the complex MYO15A genotype-phenotype correlation | Genotype-phenotype correlation analysis of MYO15A variants in autosomal recessive non-syndromic hearing loss.
Zhang J, Guan J, Wang H, Yin L, Wang D, Zhao L, Zhou H, Wang Q., Free PMC Article | 10/5/2019 |
| The hearing loss in this case was caused by novel, compound heterozygous mutations in MYO15A. | A novel nonsense mutation in MYO15A is associated with non-syndromic hearing loss: a case report.
Ma D, Shen S, Gao H, Guo H, Lin Y, Hu Y, Zhang R, Wang S., Free PMC Article | 04/20/2019 |