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    PHF11 PHD finger protein 11 [ Homo sapiens (human) ]

    Gene ID: 51131, updated on 10-Oct-2024

    GeneRIFs: Gene References Into Functions

    Submit: New GeneRIFCorrection

    GeneRIFPubMed TitleDate
    data suggest that BCAP exists as two isoforms with subtly different roles in inhibition of ciliogenesis. Both are required to prevent ciliogenesis and one additionally controls cilium length after ciliogenesis has completed.

    BCAP is a centriolar satellite protein and inhibitor of ciliogenesis.
    de Saram P, Iqbal A, Murdoch JN, Wilkinson CJ.

    		05/26/2018
    contributes to T-cell activation and viability

    A role for the atopy-associated gene PHF11 in T-cell activation and viability.
    Rahman N, Stewart G, Jones G.

    		06/18/2011
    the single nucleotide polymorphism rs1046295 of PHF11 modulates allele-specific binding by the octamer-binding transcription factor 1

    Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1).
    Holt RJ, Zhang Y, Binia A, Dixon AL, Vandiedonck C, Cookson WO, Knight JC, Moffatt MF., Free PMC Article

    		06/4/2011
    PHF11 (PHD finger protein 11) is not a major candidate gene for asthma or eczema in Chinese children

    PHF11 is not a major candidate gene for asthma or eczema in Chinese children.
    Sy HY, Chan IH, Hon EK, Kong AP, Tang NL, Li CY, Wong GW, Waye MM, Lam CW, Chan JC, Leung TF, Sy HY, Chan IH, Hon EK, Kong AP, Tang NL, Li CY, Wong GW, Waye MM, Lam CW, Chan JC, Leung TF.

    		01/1/2011
    We were unable to confirm associations of single nucleotide polymorphisms of the positional candidates DPP10 and PHF11 with wheeze. Significant associations with reported and examined eczema were only observed for DPP10.

    A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2.
    Genuneit J, Cantelmo JL, Weinmayr G, Wong GW, Cooper PJ, Riikjärv MA, Gotua M, Kabesch M, von Mutius E, Forastiere F, Crane J, Nystad W, El-Sharif N, Batlles-Garrido J, García-Marcos L, García-Hernández G, Morales-Suarez-Varela M, Nilsson L, Bråbäck L, Saraçlar Y, Weiland SK, Cookson WO, Strachan D, Moffatt MF, ISAAC Phase 2 Study Group, Genuneit J, Cantelmo JL, Weinmayr G, Wong GW, Cooper PJ, Riikjärv MA, Gotua M, Kabesch M, von Mutius E, Forastiere F, Crane J, Nystad W, El-Sharif N, Batlles-Garrido J, García-Marcos L, García-Hernández G, Morales-Suarez-Varela M, Nilsson L, Bråbäck L, Saraçlar Y, Weiland SK, Cookson WO, Strachan D, Moffatt MF, ISAAC Phase 2 Study Group.

    		04/19/2010
    rs1046295 and rs16659 associated with asthma susceptibility in a Han Chinese population

    Polymorphisms of PHF11 and DPP10 are associated with asthma and related traits in a Chinese population.
    Gao J, Li W, Willis-Owen SA, Jiang L, Ma Y, Tian X, Moffatt M, Cookson W, Lin Y, Zhang Y, Gao J, Li W, Willis-Owen SA, Jiang L, Ma Y, Tian X, Moffatt M, Cookson W, Lin Y, Zhang Y.

    		02/8/2010
    Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)

    Postural changes in blood pressure associated with interactions between candidate genes for chronic respiratory diseases and exposure to particulate matter.
    Wilker E, Mittleman MA, Litonjua AA, Poon A, Baccarelli A, Suh H, Wright RO, Sparrow D, Vokonas P, Schwartz J., Free PMC Article

    		08/12/2009
    PHF11 is unlikely to contain polymorphic loci that have a major impact on asthma susceptibility in two independent populations.

    The PHF11 gene is not associated with asthma or asthma phenotypes in two independent populations.
    McClenaghan J, Warrington NM, Jamrozik EF, Hui J, Beilby JP, Hansen J, de Klerk NH, James AL, Musk AW, Palmer LJ, McClenaghan J, Warrington NM, Jamrozik EF, Hui J, Beilby JP, Hansen J, de Klerk NH, James AL, Musk AW, Palmer LJ.

    		01/21/2010
    Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)See all PubMed (2) articles

    Early life environment, neurodevelopment and the interrelation with atopy.
    Sunyer J, Basagaña X, González JR, Júlvez J, Guerra S, Bustamante M, de Cid R, Antó JM, Torrent M.

    Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.
    Siezen CL, Bont L, Hodemaekers HM, Ermers MJ, Doornbos G, Van't Slot R, Wijmenga C, Houwelingen HC, Kimpen JL, Kimman TG, Hoebee B, Janssen R.

    		03/25/2009
    PHF11 is a regulator of T(H)1-type cytokine gene expression

    Functional characterization of the atopy-associated gene PHF11.
    Clarke E, Rahman N, Page N, Rolph MS, Stewart GJ, Jones GJ.

    		01/21/2010
    Observational study of gene-disease association. (HuGE Navigator)See all PubMed (14) articles

    PHF11 is not a major candidate gene for asthma or eczema in Chinese children.
    Sy HY, Chan IH, Hon EK, Kong AP, Tang NL, Li CY, Wong GW, Waye MM, Lam CW, Chan JC, Leung TF, Sy HY, Chan IH, Hon EK, Kong AP, Tang NL, Li CY, Wong GW, Waye MM, Lam CW, Chan JC, Leung TF.

    Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia.
    Chang JS, Wiemels JL, Chokkalingam AP, Metayer C, Barcellos LF, Hansen HM, Aldrich MC, Guha N, Urayama KY, Scélo G, Green J, May SL, Kiley VA, Wiencke JK, Buffler PA.

    Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.
    Schuurhof A, Bont L, Siezen CL, Hodemaekers H, van Houwelingen HC, Kimman TG, Hoebee B, Kimpen JL, Janssen R.

    A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2.
    Genuneit J, Cantelmo JL, Weinmayr G, Wong GW, Cooper PJ, Riikjärv MA, Gotua M, Kabesch M, von Mutius E, Forastiere F, Crane J, Nystad W, El-Sharif N, Batlles-Garrido J, García-Marcos L, García-Hernández G, Morales-Suarez-Varela M, Nilsson L, Bråbäck L, Saraçlar Y, Weiland SK, Cookson WO, Strachan D, Moffatt MF, ISAAC Phase 2 Study Group, Genuneit J, Cantelmo JL, Weinmayr G, Wong GW, Cooper PJ, Riikjärv MA, Gotua M, Kabesch M, von Mutius E, Forastiere F, Crane J, Nystad W, El-Sharif N, Batlles-Garrido J, García-Marcos L, García-Hernández G, Morales-Suarez-Varela M, Nilsson L, Bråbäck L, Saraçlar Y, Weiland SK, Cookson WO, Strachan D, Moffatt MF, ISAAC Phase 2 Study Group.

    Positionally cloned genes and age-specific effects in asthma and atopy: an international population-based cohort study (ECRHS).
    Castro-Giner F, de Cid R, Gonzalez JR, Jarvis D, Heinrich J, Janson C, Omenaas ER, Matheson MC, Pin I, Antó JM, Wjst M, Estivill X, Kogevinas M.

    Analyses of associations between three positionally cloned asthma candidate genes and asthma or asthma-related phenotypes in a Chinese population.
    Zhou H, Hong X, Jiang S, Dong H, Xu X, Xu X.

    Polymorphisms of PHF11 and DPP10 are associated with asthma and related traits in a Chinese population.
    Gao J, Li W, Willis-Owen SA, Jiang L, Ma Y, Tian X, Moffatt M, Cookson W, Lin Y, Zhang Y, Gao J, Li W, Willis-Owen SA, Jiang L, Ma Y, Tian X, Moffatt M, Cookson W, Lin Y, Zhang Y.

    The PHF11 gene is not associated with asthma or asthma phenotypes in two independent populations.
    McClenaghan J, Warrington NM, Jamrozik EF, Hui J, Beilby JP, Hansen J, de Klerk NH, James AL, Musk AW, Palmer LJ, McClenaghan J, Warrington NM, Jamrozik EF, Hui J, Beilby JP, Hansen J, de Klerk NH, James AL, Musk AW, Palmer LJ.

    Assessing the reproducibility of asthma candidate gene associations, using genome-wide data.
    Rogers AJ, Raby BA, Lasky-Su JA, Murphy A, Lazarus R, Klanderman BJ, Sylvia JS, Ziniti JP, Lange C, Celedón JC, Silverman EK, Weiss ST.

    Analyses of associations with asthma in four asthma population samples from Canada and Australia.
    Daley D, Lemire M, Akhabir L, Chan-Yeung M, He JQ, McDonald T, Sandford A, Stefanowicz D, Tripp B, Zamar D, Bosse Y, Ferretti V, Montpetit A, Tessier MC, Becker A, Kozyrskyj AL, Beilby J, McCaskie PA, Musk B, Warrington N, James A, Laprise C, Palmer LJ, Paré PD, Hudson TJ.

    Positionally cloned asthma susceptibility gene polymorphisms and disease risk in the British 1958 Birth Cohort.
    Blakey JD, Sayers I, Ring SM, Strachan DP, Hall IP.

    Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.
    Janssen R, Bont L, Siezen CL, Hodemaekers HM, Ermers MJ, Doornbos G, van 't Slot R, Wijmenga C, Goeman JJ, Kimpen JL, van Houwelingen HC, Kimman TG, Hoebee B.

    Comprehensive testing of positionally cloned asthma genes in two populations.
    Hersh CP, Raby BA, Soto-Quirós ME, Murphy AJ, Avila L, Lasky-Su J, Sylvia JS, Klanderman BJ, Lange C, Weiss ST, Celedón JC, Hersh CP, Raby BA, Soto-Quirós ME, Murphy AJ, Avila L, Lasky-Su J, Sylvia JS, Klanderman BJ, Lange C, Weiss ST, Celedón JC.

    Polymorphisms within the PHF11 gene at chromosome 13q14 are associated with childhood atopic dermatitis.
    Jang N, Stewart G, Jones G.

    		03/13/2008
    Results provide some further support for the role of genetic variation in PHF11 in asthma susceptibility.

    Comprehensive testing of positionally cloned asthma genes in two populations.
    Hersh CP, Raby BA, Soto-Quirós ME, Murphy AJ, Avila L, Lasky-Su J, Sylvia JS, Klanderman BJ, Lange C, Weiss ST, Celedón JC, Hersh CP, Raby BA, Soto-Quirós ME, Murphy AJ, Avila L, Lasky-Su J, Sylvia JS, Klanderman BJ, Lange C, Weiss ST, Celedón JC., Free PMC Articles: PMC2048676, PMC2048676

    		01/21/2010
    Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma.

    Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma.
    Zhang Y, Leaves NI, Anderson GG, Ponting CP, Broxholme J, Holt R, Edser P, Bhattacharyya S, Dunham A, Adcock IM, Pulleyn L, Barnes PJ, Harper JI, Abecasis G, Cardon L, White M, Burton J, Matthews L, Mott R, Ross M, Cox R, Moffatt MF, Cookson WO.

    		01/21/2010
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