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    HP1BP3 heterochromatin protein 1 binding protein 3 [ Homo sapiens (human) ]

    Gene ID: 50809, updated on 6-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.

    EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.
    Yu T, Zhou F, Tian W, Xu R, Wang B, Zeng A, Zhou Z, Li M, Wang Y, Zhang J.

    02/14/2023
    A fail-safe system to prevent oncogenesis by senescence is targeted by SV40 small T antigen.

    A fail-safe system to prevent oncogenesis by senescence is targeted by SV40 small T antigen.
    Oshikawa K, Matsumoto M, Kodama M, Shimizu H, Nakayama KI.

    11/28/2020
    HP1BP3 protein maintains heterochromatin integrity during G1-S progression and regulates the duration of G1 phase to critically influence cell proliferative capacity.

    Profiling of the Chromatin-associated Proteome Identifies HP1BP3 as a Novel Regulator of Cell Cycle Progression.
    Dutta B, Ren Y, Hao P, Sim KH, Cheow E, Adav S, Tam JP, Sze SK., Free PMC Article

    01/13/2018
    HP1BP3 promotes co-transcriptional miRNA processing via chromatin retention of nascent pri-miRNA transcripts.

    HP1BP3, a Chromatin Retention Factor for Co-transcriptional MicroRNA Processing.
    Liu H, Liang C, Kollipara RK, Matsui M, Ke X, Jeong BC, Wang Z, Yoo KS, Yadav GP, Kinch LN, Grishin NV, Nam Y, Corey DR, Kittler R, Liu Q., Free PMC Article

    09/2/2017
    DNA methylation at early antenatal time points associated with changes in estradiol and allopregnanolone and postpartum depression

    Replication of Epigenetic Postpartum Depression Biomarkers and Variation with Hormone Levels.
    Osborne L, Clive M, Kimmel M, Gispen F, Guintivano J, Brown T, Cox O, Judy J, Meilman S, Braier A, Beckmann MW, Kornhuber J, Fasching PA, Goes F, Payne JL, Binder EB, Kaminsky Z., Free PMC Article

    01/14/2017
    HP1BP3 is a component of heterochromatin, and its recruitment is dependent on a functional interaction with HP1 proteins.

    HP1BP3 is a novel histone H1 related protein with essential roles in viability and growth.
    Garfinkel BP, Melamed-Book N, Anuka E, Bustin M, Orly J., Free PMC Article

    03/11/2016
    HP1BP3 regulates hepatic expression of IGF1 and its binding proteins in mice, thus modulating the endocrine IGF1 pathway.

    Proportionate Dwarfism in Mice Lacking Heterochromatin Protein 1 Binding Protein 3 (HP1BP3) Is Associated With Alterations in the Endocrine IGF-1 Pathway.
    Garfinkel BP, Arad S, Le PT, Bustin M, Rosen CJ, Gabet Y, Orly J., Free PMC Article

    03/11/2016
    Quantitative profiling of chromatome dynamics reveals an important role for HP1BP3 in hypoxia-induced oncogenesis.

    Quantitative profiling of chromatome dynamics reveals a novel role for HP1BP3 in hypoxia-induced oncogenesis.
    Dutta B, Yan R, Lim SK, Tam JP, Sze SK., Free PMC Article

    07/25/2015
    found two biomarker loci at HP1BP3 and TTC9B, which predicted postpartum depression

    Seeing the future: epigenetic biomarkers of postpartum depression.
    Kaminsky Z, Payne J., Free PMC Article

    11/29/2014
    Observational study of gene-disease association. (HuGE Navigator)

    Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.
    Flachsbart F, Franke A, Kleindorp R, Caliebe A, Blanché H, Schreiber S, Nebel A.

    12/5/2010
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
    HP1-BP74 directly binds to HP1, and its middle region associates with linker DNA at the entry/exit site of nucleosomal DNA in vitro

    The middle region of an HP1-binding protein, HP1-BP74, associates with linker DNA at the entry/exit site of nucleosomal DNA.
    Hayashihara K, Uchiyama S, Shimamoto S, Kobayashi S, Tomschik M, Wakamatsu H, No D, Sugahara H, Hori N, Noda M, Ohkubo T, Zlatanova J, Matsunaga S, Fukui K., Free PMC Article

    03/29/2010
    Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia.

    Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.
    Martins-de-Souza D, Gattaz WF, Schmitt A, Rewerts C, Maccarrone G, Dias-Neto E, Turck CW.

    01/28/2009
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