The tumor suppressor Parkin exerts anticancer effects through regulating mitochondrial GAPDH activity.
Sun X, Ye G, Li J, Yuan L, Bai G, Xu YJ, Zhang J.

Cooperative Substructure and Energetics of Allosteric Regulation of the Catalytic Core of the E3 Ubiquitin Ligase Parkin by Phosphorylated Ubiquitin.
Ye X, Kotaru S, Lopes R, Cravens S, Lasagna M, Wand AJ., Free PMC Article

Activation of parkin by a molecular glue.
Sauvé V, Stefan E, Croteau N, Goiran T, Fakih R, Bansal N, Hadzipasic A, Fang J, Murugan P, Chen S, Fon EA, Hirst WD, Silvian LF, Trempe JF, Gehring K., Free PMC Article

Naturally occurring hyperactive variants of human parkin.
Huq TS, Luo J, Fakih R, Sauvé V, Gehring K., Free PMC Article

Additional feedforward mechanism of Parkin activation via binding of phospho-UBL and RING0 in trans.
Lenka DR, Dahe SV, Antico O, Sahoo P, Prescott AR, Muqit MMK, Kumar A., Free PMC Article

Deciphering the neuroprotective mechanisms of RACK1 in cerebral ischemia-reperfusion injury: Pioneering insights into mitochondrial autophagy and the PINK1/Parkin axis.
Zhao L, Chen Y, Li H, Ding X, Li J., Free PMC Article

PINK1/Park2-Mediated Mitophagy Relieve Non-Alcoholic Fatty Liver Disease.
He H, Tang Y, Zhuang L, Zheng Y, Huang X., Free PMC Article

Interplay between α-synuclein and parkin genes: Insights of Parkinson's disease.
Sharma K, Chib S, Gupta A, Singh R, Chalotra R.

Parkin mRNA Expression Levels in Peripheral Blood Mononuclear Cells in Parkin-Related Parkinson's Disease.
Papagiannakis N, Liu H, Koros C, Simitsi AM, Stamelou M, Maniati M, Buena-Atienza E, Kartanou C, Karadima G, Makrythanasis P, Vatsellas G, Valente EM, Gasser T, Stefanis L.

MiR-181c-5p Regulates Lung Adenocarcinoma Progression via Targeting PRKN.
Wang J, Li M, Wang M, Yang J, Li D, Hao Y.

Association between copy number variations in parkin (PRKN) and schizophrenia and autism spectrum disorder: A case-control study.
Lo T, Kushima I, Kimura H, Aleksic B, Okada T, Kato H, Inada T, Nawa Y, Torii Y, Yamamoto M, Kimura R, Funabiki Y, Kosaka H, Numata S, Kasai K, Sasaki T, Yokoyama S, Munesue T, Hashimoto R, Yasuda Y, Fujimoto M, Usami M, Itokawa M, Arai M, Ohi K, Someya T, Watanabe Y, Egawa J, Takahashi T, Suzuki M, Yamasue H, Iwata N, Ikeda M, Ozaki N., Free PMC Article

Parkin inhibits proliferation and migration of bladder cancer via ubiquitinating Catalase.
Zhang R, Jiang W, Wang G, Zhang Y, Liu W, Li M, Yu J, Yan X, Zhou F, Du W, Qian K, Xiao Y, Liu T, Ju L, Wang X., Free PMC Article

Pregnancy, fertile life factors, and associated clinical course in PRKN early-onset Parkinson's disease.
Bovenzi R, Conti M, Degoli GR, Cerroni R, Artusi CA, Pierantozzi M, Stefani A, Mercuri NB, Schirinzi T., Free PMC Article

Long-Read Sequencing Resolves a Complex Structural Variant in PRKN Parkinson's Disease.
Daida K, Funayama M, Billingsley KJ, Malik L, Miano-Burkhardt A, Leonard HL, Makarious MB, Iwaki H, Ding J, Gibbs JR, Ishiguro M, Yoshino H, Ogaki K, Oyama G, Nishioka K, Nonaka R, Akamatsu W, Blauwendraat C, Hattori N.,

Parkinson's disease-linked parkin mutation disrupts recycling of synaptic vesicles in human dopaminergic neurons.
Song P, Peng W, Sauve V, Fakih R, Xie Z, Ysselstein D, Krainc T, Wong YC, Mencacci NE, Savas JN, Surmeier DJ, Gehring K, Krainc D.

History of Parkinson's Disease-Associated Gene, Parkin: Research over a Quarter Century in Quest of Finding the Physiological Substrate.
Kitada T, Ardah MT, Haque ME., Free PMC Article

Prohibitin2/PHB2, Transcriptionally Regulated by GABPA, Inhibits Cell Growth via PRKN/Parkin-dependent Mitophagy in Endometriosis.
Deng Y, Lou T, Kong L, Liu C.

Parkin-Mediated Mitophagy by TGF-β Is Connected with Hepatic Stellate Cell Activation.
Lee JH, Kim KM, Jung EH, Lee HR, Yang JH, Cho SS, Ki SH., Free PMC Article

Parkin Deficiency Suppresses Antigen Presentation to Promote Tumor Immune Evasion and Immunotherapy Resistance.
Perales-Linares R, Leli NM, Mohei H, Beghi S, Rivera OD, Kostopoulos N, Giglio A, George SS, Uribe-Herranz M, Costabile F, Pierini S, Pustylnikov S, Skoufos G, Barash Y, Hatzigeorgiou AG, Koumenis C, Maity A, Lotze MT, Facciabene A., Free PMC Article

Tumor suppressor Parkin induces p53-mediated cell cycle arrest in human lung and colorectal cancer cells.
Jung BC, Kim SH, Cho Y, Kim YS., Free PMC Article

Mitochondria-Endoplasmic Reticulum Contact Sites Dynamics and Calcium Homeostasis Are Differentially Disrupted in PINK1-PD or PRKN-PD Neurons.
Grossmann D, Malburg N, Glaß H, Weeren V, Sondermann V, Pfeiffer JF, Petters J, Lukas J, Seibler P, Klein C, Grünewald A, Hermann A.

Parkin regulates IGF2BP3 through ubiquitination in the tumourigenesis of cervical cancer.
Sun X, Ye G, Li J, Shou H, Bai G, Zhang J., Free PMC Article

Alpha-synuclein-associated changes in PINK1-PRKN-mediated mitophagy are disease context dependent.
Hou X, Chen TH, Koga S, Bredenberg JM, Faroqi AH, Delenclos M, Bu G, Wszolek ZK, Carr JA, Ross OA, McLean PJ, Murray ME, Dickson DW, Fiesel FC, Springer W., Free PMC Article

In search for mitochondrial biomarkers of Parkinson's disease: Findings in parkin-mutant human fibroblasts.
Kamienieva I, Charzyńska A, Duszyński J, Malińska D, Szczepanowska J.

The effect of Parkin gene S/N 167 polymorphism on resting spontaneous brain functional activity in Parkinson's Disease.
Zheng J, Chen L, Cai G, Wang Y, Huang J, Lin X, Li Y, Yu Q, Chen X, Shi Y, Ye Q.