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    PRDX1 peroxiredoxin 1 [ Homo sapiens (human) ]

    Gene ID: 5052, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The interaction of PRDX1 with Cofilin promotes oral squamous cell carcinoma metastasis.

    The interaction of PRDX1 with Cofilin promotes oral squamous cell carcinoma metastasis.
    Shen Y, You Z, Li L, Tang X, Shan X.

    09/11/2024
    LncFASA promotes cancer ferroptosis via modulating PRDX1 phase separation.

    LncFASA promotes cancer ferroptosis via modulating PRDX1 phase separation.
    Fan X, Liu F, Wang X, Wang Y, Chen Y, Shi C, Su X, Tan M, Yan Q, Peng J, Shao J, Xiong Y, Lin A.

    03/5/2024
    The PRX-1/TLR4 axis promotes hypoxia-induced radiotherapy resistance in non-small cell lung cancer by targeting the NF-kappaB/p65 pathway.

    The PRX-1/TLR4 axis promotes hypoxia-induced radiotherapy resistance in non-small cell lung cancer by targeting the NF-κB/p65 pathway.
    Hao J, Song Z, Su J, Li L, Zou L, Zou K.

    09/6/2023
    Peroxiredoxin 1 aggravates acute kidney injury by promoting inflammation through Mincle/Syk/NF-kappaB signaling.

    Peroxiredoxin 1 aggravates acute kidney injury by promoting inflammation through Mincle/Syk/NF-κB signaling.
    Li S, Zhang Y, Lu R, Lv X, Lei Q, Tang D, Dai Q, Deng Z, Liao X, Tu S, Yang H, Xie Y, Meng J, Yuan Q, Qin J, Pu J, Peng Z, Tao L.

    07/25/2023
    A metabolic map of the DNA damage response identifies PRDX1 in the control of nuclear ROS scavenging and aspartate availability.

    A metabolic map of the DNA damage response identifies PRDX1 in the control of nuclear ROS scavenging and aspartate availability.
    Moretton A, Kourtis S, Gañez Zapater A, Calabrò C, Espinar Calvo ML, Fontaine F, Darai E, Abad Cortel E, Block S, Pascual-Reguant L, Pardo-Lorente N, Ghose R, Vander Heiden MG, Janic A, Müller AC, Loizou JI, Sdelci S., Free PMC Article

    07/13/2023
    PRDX1 stimulates non-small-cell lung carcinoma to proliferate via the Wnt/beta-Catenin signaling.

    PRDX1 stimulates non-small-cell lung carcinoma to proliferate via the Wnt/β-Catenin signaling.
    Song C, Xiong G, Yang S, Wei X, Ye X, Huang W, Zhang R.

    03/16/2023
    Upregulation of exofacial peroxiredoxin-thioredoxin system of lymphocytes and monocytes in preeclampsia.

    Upregulation of exofacial peroxiredoxin-thioredoxin system of lymphocytes and monocytes in preeclampsia.
    Alasztics B, Kovács ÁF, Pállinger É, Szabó-Taylor KÉ, Szabó G, Molvarec A, Koller A, Rigó J Jr.

    02/28/2023
    The role of human umbilical cord mesenchymal stem cells-derived exosomal microRNA-431-5p in survival and prognosis of colorectal cancer patients.

    The role of human umbilical cord mesenchymal stem cells-derived exosomal microRNA-431-5p in survival and prognosis of colorectal cancer patients.
    Qu M, Li J, Hong Z, Jia F, He Y, Yuan L., Free PMC Article

    11/19/2022
    Membrane Bound Peroxiredoxin-1 Serves as a Biomarker for In Vivo Detection of Sessile Serrated Adenomas.

    Membrane Bound Peroxiredoxin-1 Serves as a Biomarker for In Vivo Detection of Sessile Serrated Adenomas.
    Jaiswal S, Joshi B, Chen J, Wang F, Dame MK, Spence JR, Newsome GM, Katz EL, Shah YM, Ramakrishnan SK, Li G, Lee M, Appelman HD, Kuick R, Wang TD., Free PMC Article

    04/9/2022
    PRDX1 gene-related epi-cblC disease is a common type of inborn error of cobalamin metabolism with mono- or bi-allelic MMACHC epimutations.

    PRDX1 gene-related epi-cblC disease is a common type of inborn error of cobalamin metabolism with mono- or bi-allelic MMACHC epimutations.
    Cavicchi C, Oussalah A, Falliano S, Ferri L, Gozzini A, Gasperini S, Motta S, Rigoldi M, Parenti G, Tummolo A, Meli C, Menni F, Furlan F, Daniotti M, Malvagia S, la Marca G, Chery C, Morange PE, Tregouet D, Donati MA, Guerrini R, Guéant JL, Morrone A., Free PMC Article

    02/5/2022
    Guanine Nucleotide-Binding Protein G(i) Subunit Alpha 2 Exacerbates NASH Progression by Regulating Peroxiredoxin 1-Related Inflammation and Lipophagy.

    Guanine Nucleotide-Binding Protein G(i) Subunit Alpha 2 Exacerbates NASH Progression by Regulating Peroxiredoxin 1-Related Inflammation and Lipophagy.
    Zhang Z, Ji Z, He J, Lu Y, Tian W, Zheng C, Chen H, Zhang Q, Yang F, Zhang M, Yin Y, Jiang R, Chu WM, Zhang W, Sun B.

    01/15/2022
    Clinicopathological Significance of FOXO4 Expression and Correlation with Prx1 in Head and Neck Squamous Cell Carcinoma.

    Clinicopathological Significance of FOXO4 Expression and Correlation with Prx1 in Head and Neck Squamous Cell Carcinoma.
    Lu Y, Shen Y, Li L, Zhang M, Wang M, Ge L, Yang J, Tang X., Free PMC Article

    12/18/2021
    Association of Peroxiredoxin 1 and brain-derived neurotrophic factor serum levels with depression and anxiety symptoms in patients with irritable bowel syndrome.

    Association of Peroxiredoxin 1 and brain-derived neurotrophic factor serum levels with depression and anxiety symptoms in patients with irritable bowel syndrome.
    Zhang Y, Bi YX, Chen J, Li S, Wu XX, Zhang L, Lin ZJ, Han S, Ding SZ.

    12/18/2021
    Peroxiredoxin-1 Tyr194 phosphorylation regulates LOX-dependent extracellular matrix remodelling in breast cancer.

    Peroxiredoxin-1 Tyr194 phosphorylation regulates LOX-dependent extracellular matrix remodelling in breast cancer.
    Attaran S, Skoko JJ, Hopkins BL, Wright MK, Wood LE, Asan A, Woo HA, Feinberg A, Neumann CA., Free PMC Article

    12/18/2021
    Prognostic Value of Peroxiredoxin-1 Expression in Patients with Solid Tumors: a Meta-Analysis of Cohort Study.

    Prognostic Value of Peroxiredoxin-1 Expression in Patients with Solid Tumors: a Meta-Analysis of Cohort Study.
    Jiao L, Wei J, Ye J, Zhang C., Free PMC Article

    10/30/2021
    Peroxiredoxin 1 Interacts with TBK1/IKKepsilon and Negatively Regulates Pseudorabies Virus Propagation by Promoting Innate Immunity.

    Peroxiredoxin 1 Interacts with TBK1/IKKε and Negatively Regulates Pseudorabies Virus Propagation by Promoting Innate Immunity.
    Lv L, Bai J, Gao Y, Jin L, Wang X, Cao M, Liu X, Jiang P., Free PMC Article

    10/16/2021
    Cullin-5 neddylation-mediated NOXA degradation is enhanced by PRDX1 oligomers in colorectal cancer.

    Cullin-5 neddylation-mediated NOXA degradation is enhanced by PRDX1 oligomers in colorectal cancer.
    Xu S, Ma Y, Tong Q, Yang J, Liu J, Wang Y, Li G, Zeng J, Fang S, Li F, Xie X, Zhang J., Free PMC Article

    09/18/2021
    Decoy receptor 2 mediation of the senescent phenotype of tubular cells by interacting with peroxiredoxin 1 presents a novel mechanism of renal fibrosis in diabetic nephropathy.

    Decoy receptor 2 mediation of the senescent phenotype of tubular cells by interacting with peroxiredoxin 1 presents a novel mechanism of renal fibrosis in diabetic nephropathy.
    Jia C, Ke-Hong C, Fei X, Huan-Zi D, Jie Y, Li-Ming W, Xiao-Yue W, Jian-Guo Z, Ya-Ni H.

    08/14/2021
    A curious case of cysteines in human peroxiredoxin I.

    A curious case of cysteines in human peroxiredoxin I.
    Mohammad A, Saini RV, Kumar R, Sharma D, Saini NK, Gupta A, Thakur P, Winterbourn CC, Saini AK., Free PMC Article

    07/3/2021
    PRDX1 Counteracts Catastrophic Telomeric Cleavage Events That Are Triggered by DNA Repair Activities Post Oxidative Damage.

    PRDX1 Counteracts Catastrophic Telomeric Cleavage Events That Are Triggered by DNA Repair Activities Post Oxidative Damage.
    Ahmed W, Lingner J.

    05/8/2021
    Peroxiredoxin-1 regulates lipid peroxidation in corneal endothelial cells.

    Peroxiredoxin-1 regulates lipid peroxidation in corneal endothelial cells.
    Lovatt M, Adnan K, Kocaba V, Dirisamer M, Peh GSL, Mehta JS., Free PMC Article

    04/17/2021
    Peroxiredoxin I deficiency increases keratinocyte apoptosis in a skin tumor model via the ROS-p38 MAPK pathway.

    Peroxiredoxin I deficiency increases keratinocyte apoptosis in a skin tumor model via the ROS-p38 MAPK pathway.
    Han YH, Zhang YQ, Jin MH, Jin YH, Qiu MY, Li WL, He C, Yu LY, Hyun JW, Lee J, Yoon DY, Sun HN, Kwon T.

    02/27/2021
    Peroxiredoxin 1 as an inflammatory marker in diarrhea-predominant and postinfectious irritable bowel syndrome.

    Peroxiredoxin 1 as an inflammatory marker in diarrhea-predominant and postinfectious irritable bowel syndrome.
    Zhang Y, Wu XX, Li S, Wu JF, Han S, Lin ZJ, Ding SZ, Gong WJ.

    02/13/2021
    Prdx1 promotes the loss of primary cilia in esophageal squamous cell carcinoma.

    Prdx1 promotes the loss of primary cilia in esophageal squamous cell carcinoma.
    Chen Q, Li J, Yang X, Ma J, Gong F, Liu Y., Free PMC Article

    01/23/2021
    Deciphering the in vivo redox behavior of human peroxiredoxins I and II by expressing in budding yeast.

    Deciphering the in vivo redox behavior of human peroxiredoxins I and II by expressing in budding yeast.
    Kumar R, Mohammad A, Saini RV, Chahal A, Wong CM, Sharma D, Kaur S, Kumar V, Winterbourn CC, Saini AK.

    09/5/2020
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