| Role of NADPH Oxidase 4 on Dry Eye Syndrome in Mice. | Role of NADPH Oxidase 4 on Dry Eye Syndrome in Mice.
Guo M, Liu T, Miao Y, Pan X, Liu B. | 09/25/2024 |
| GDF11 OVEREXPRESSION ALLEVIATES SEPSIS-INDUCED LUNG MICROVASCULAR ENDOTHELIAL BARRIER DAMAGE BY ACTIVATING SIRT1/NOX4 SIGNALING TO INHIBIT FERROPTOSIS. | GDF11 OVEREXPRESSION ALLEVIATES SEPSIS-INDUCED LUNG MICROVASCULAR ENDOTHELIAL BARRIER DAMAGE BY ACTIVATING SIRT1/NOX4 SIGNALING TO INHIBIT FERROPTOSIS.
Wu Z, Xi Q, Zhao Q, Zhu S. | 08/15/2024 |
| NOX4 and its association with myeloperoxidase and osteopontin in regulating endochondral ossification. | NOX4 and its association with myeloperoxidase and osteopontin in regulating endochondral ossification.
Ko K, Choi S, Jo M, Kim C, Boonpraman N, Youm J, Yi SS., Free PMC Article | 08/14/2024 |
| Effects of Nox4 upregulation on PECAM-1 expression in a mouse model of diabetic retinopathy. | Effects of Nox4 upregulation on PECAM-1 expression in a mouse model of diabetic retinopathy.
Wang J, Lai DA, Wang JJ, Zhang SX., Free PMC Article | 07/31/2024 |
| NADPH oxidase 4-derived hydrogen peroxide counterbalances testosterone-induced endothelial dysfunction and migration. | NADPH oxidase 4-derived hydrogen peroxide counterbalances testosterone-induced endothelial dysfunction and migration.
Alves JV, da Costa RM, Awata WMC, Bruder-Nascimento A, Singh S, Tostes RC, Bruder-Nascimento T., | 06/30/2024 |
| Hederagenin improves renal fibrosis in diabetic nephropathy by regulating Smad3/NOX4/SLC7A11 signaling-mediated tubular cell ferroptosis. | Hederagenin improves renal fibrosis in diabetic nephropathy by regulating Smad3/NOX4/SLC7A11 signaling-mediated tubular cell ferroptosis.
Jia J, Tan R, Xu L, Wang H, Li J, Su H, Zhong X, Liu P, Wang L. | 06/17/2024 |
| C/EBPalpha aggravates renal fibrosis in CKD through the NOX4-ROS-apoptosis pathway in tubular epithelial cells. | C/EBPα aggravates renal fibrosis in CKD through the NOX4-ROS-apoptosis pathway in tubular epithelial cells.
Xia Z, Wei Z, Li X, Liu Y, Gu X, Huang S, Zhang X, Wang W. | 02/21/2024 |
| Mitochondria- and NOX4-dependent antioxidant defense mitigates progression to nonalcoholic steatohepatitis in obesity. | Mitochondria- and NOX4-dependent antioxidant defense mitigates progression to nonalcoholic steatohepatitis in obesity.
Greatorex S, Kaur S, Xirouchaki CE, Goh PK, Wiede F, Genders AJ, Tran M, Jia Y, Raajendiran A, Brown WA, McLean CA, Sadoshima J, Watt MJ, Tiganis T., Free PMC Article | 02/9/2024 |
| NADPH oxidase 4 in mouse beta cells participates in inflammation on chronic nutrient overload. | NADPH oxidase 4 in mouse β cells participates in inflammation on chronic nutrient overload.
Holendová B, Benáková Š, Křivonosková M, Pavluch V, Tauber J, Gabrielová E, Ježek P, Plecitá-Hlavatá L. | 02/5/2024 |
| Aging-related NOX4-Nrf2 redox imbalance increases susceptibility to cisplatin-induced acute kidney injury by regulating mitophagy. | Aging-related NOX4-Nrf2 redox imbalance increases susceptibility to cisplatin-induced acute kidney injury by regulating mitophagy.
Hu J, Hou W, Ma N, Zhang Y, Liu X, Wang Y, Ci X. | 01/3/2024 |
| Cardiomyocyte NOX4 regulates resident macrophage-mediated inflammation and diastolic dysfunction in stress cardiomyopathy. | Cardiomyocyte NOX4 regulates resident macrophage-mediated inflammation and diastolic dysfunction in stress cardiomyopathy.
Vendrov AE, Xiao H, Lozhkin A, Hayami T, Hu G, Brody MJ, Sadoshima J, Zhang YY, Runge MS, Madamanchi NR., Free PMC Article | 10/30/2023 |
| miR-100a-5p-enriched exosomes derived from mesenchymal stem cells enhance the anti-oxidant effect in a Parkinson's disease model via regulation of Nox4/ROS/Nrf2 signaling. | miR-100a-5p-enriched exosomes derived from mesenchymal stem cells enhance the anti-oxidant effect in a Parkinson's disease model via regulation of Nox4/ROS/Nrf2 signaling.
He S, Wang Q, Chen L, He YJ, Wang X, Qu S., Free PMC Article | 10/28/2023 |
| The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression. | The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression.
Peñuelas-Haro I, Espinosa-Sotelo R, Crosas-Molist E, Herranz-Itúrbide M, Caballero-Díaz D, Alay A, Solé X, Ramos E, Serrano T, Martínez-Chantar ML, Knaus UG, Cuezva JM, Zorzano A, Bertran E, Fabregat I., Free PMC Article | 10/20/2023 |
| Downregulation of NOX4 improves airway remodeling and inflammation by the TGF-beta1-Smad2/3 pathway in asthma. | Downregulation of NOX4 improves airway remodeling and inflammation by the TGF-β1-Smad2/3 pathway in asthma.
Xuan A, Yang M, Xia Q, Sun Q. | 10/10/2023 |
| Adipocyte-Derived Exosomal NOX4-Mediated Oxidative Damage Induces Premature Placental Senescence in Obese Pregnancy. | Adipocyte-Derived Exosomal NOX4-Mediated Oxidative Damage Induces Premature Placental Senescence in Obese Pregnancy.
Tao Y, Chen W, Xu H, Xu J, Yang H, Luo X, Chen M, He J, Bai Y, Qi H., Free PMC Article | 08/30/2023 |
| Role of Nox4 in Mitigating Inflammation and Fibrosis in Dextran Sulfate Sodium-Induced Colitis. | Role of Nox4 in Mitigating Inflammation and Fibrosis in Dextran Sulfate Sodium-Induced Colitis.
Lee Y, Kim SH, Jeong H, Kim KH, Jeon D, Cho Y, Lee D, Nam KT., Free PMC Article | 08/23/2023 |
| Interruption of TRPC6-NFATC1 signaling inhibits NADPH oxidase 4 and VSMCs phenotypic switch in intracranial aneurysm. | Interruption of TRPC6-NFATC1 signaling inhibits NADPH oxidase 4 and VSMCs phenotypic switch in intracranial aneurysm.
Sun ZH, Liu F, Kong LL, Ji PM, Huang L, Zhou HM, Sun R, Luo J, Li WZ. | 08/10/2023 |
| Vasoprotective effects of NOX4 are mediated via polymerase and transient receptor potential melastatin 2 cation channels in endothelial cells. | Vasoprotective effects of NOX4 are mediated via polymerase and transient receptor potential melastatin 2 cation channels in endothelial cells.
Alves-Lopes R, Lacchini S, Neves KB, Harvey A, Montezano AC, Touyz RM., Free PMC Article | 08/9/2023 |
| NOX4-TIM23 interaction regulates NOX4 mitochondrial import and metabolic reprogramming. | NOX4-TIM23 interaction regulates NOX4 mitochondrial import and metabolic reprogramming.
Pandey J, Larson-Casey JL, Patil MH, Joshi R, Jiang CS, Zhou Y, He C, Carter AB., Free PMC Article | 06/13/2023 |
| Blockade of Activin Receptor IIB Protects Arthritis Pathogenesis by Non-Amplification of Activin A-ACVR2B-NOX4 Axis Pathway. | Blockade of Activin Receptor IIB Protects Arthritis Pathogenesis by Non-Amplification of Activin A-ACVR2B-NOX4 Axis Pathway.
Jeon J, Lee H, Jeon MS, Kim SJ, Choi C, Kim KW, Yang DJ, Lee S, Bae YS, Choi WI, Jung J, Eyun SI, Yang S., Free PMC Article | 05/20/2023 |
| NOX4 as a critical effector mediating neuroinflammatory cytokines, myeloperoxidase and osteopontin, specifically in astrocytes in the hippocampus in Parkinson's disease. | NOX4 as a critical effector mediating neuroinflammatory cytokines, myeloperoxidase and osteopontin, specifically in astrocytes in the hippocampus in Parkinson's disease.
Boonpraman N, Yoon S, Kim CY, Moon JS, Yi SS., Free PMC Article | 05/17/2023 |
| NADPH oxidase 4 contributes to oxidative stress in a mouse model of myocardial infarction. | NADPH oxidase 4 contributes to oxidative stress in a mouse model of myocardial infarction.
Huang Q, Chen Y., Free PMC Article | 05/15/2023 |
| NADPH oxidase 4 regulate the glycolytic metabolic reprogramming of microglial cells to promote M1 polarization. | NADPH oxidase 4 regulate the glycolytic metabolic reprogramming of microglial cells to promote M1 polarization.
Zhai L, Ruan S, Wang J, Guan Q, Zha L. | 05/15/2023 |
| Osteoporotic bone loss from excess iron accumulation is driven by NOX4-triggered ferroptosis in osteoblasts. | Osteoporotic bone loss from excess iron accumulation is driven by NOX4-triggered ferroptosis in osteoblasts.
Zhang H, Wang A, Li G, Zhai Q, Huang Z, Wang X, Cao Z, Liu L, Liu G, Chen B, Zhu K, Xu Y, Xu Y. | 02/28/2023 |
| NADPH oxidase 4 is dispensable for skin myofibroblast differentiation and wound healing. | NADPH oxidase 4 is dispensable for skin myofibroblast differentiation and wound healing.
Siedlar AM, Seredenina T, Faivre A, Cambet Y, Stasia MJ, André-Lévigne D, Bochaton-Piallat ML, Pittet-Cuénod B, de Seigneux S, Krause KH, Modarressi A, Jaquet V., Free PMC Article | 02/24/2023 |