| MINK1 deficiency stimulates nucleus pulposus cell pyroptosis and exacerbates intervertebral disc degeneration. | MINK1 deficiency stimulates nucleus pulposus cell pyroptosis and exacerbates intervertebral disc degeneration.
Zhan K, Zhu K, Gu B, Yao S, Fu F, Zeng H, Tian K, Ji W, Jin H, Tong P, Wu C, Yue M, Ruan H. | 06/10/2024 |
| The serine/threonine kinase MINK1 directly regulates the function of promigratory proteins. | The serine/threonine kinase MINK1 directly regulates the function of promigratory proteins.
Daulat AM, Wagner MS, Audebert S, Kowalczewska M, Ariey-Bonnet J, Finetti P, Bertucci F, Camoin L, Borg JP. | 10/1/2022 |
| Multi-Omic Investigations of a 17-19 Translocation Links MINK1 Disruption to Autism, Epilepsy and Osteoporosis. | Multi-Omic Investigations of a 17-19 Translocation Links MINK1 Disruption to Autism, Epilepsy and Osteoporosis.
Eisfeldt J, Schuy J, Stattin EL, Kvarnung M, Falk A, Feuk L, Lindstrand A., Free PMC Article | 09/3/2022 |
| LncRNA SNHG14 contributes to proinflammatory cytokine production in rheumatoid arthritis via the regulation of the miR-17-5p/MINK1-JNK pathway. | LncRNA SNHG14 contributes to proinflammatory cytokine production in rheumatoid arthritis via the regulation of the miR-17-5p/MINK1-JNK pathway.
Zhang J, Lei H, Li X. | 11/22/2021 |
| Results find MINK1 interacting with full-length and truncated APC. Its is negatively regulated by APC independently of b-catenin. MINK1 localizes to cell-cell junctions and enhances cell adhesion and proliferation. | Identification of Endogenous Adenomatous Polyposis Coli Interaction Partners and β-Catenin-Independent Targets by Proteomics.
Popow O, Paulo JA, Tatham MH, Volk MS, Rojas-Fernandez A, Loyer N, Newton IP, Januschke J, Haigis KM, Näthke I., Free PMC Article | 06/20/2020 |
| MINK plays a functional role in the IRES-mediated translation of EV71 viral RNA and may provide a potential target for the development of specific antiviral strategies against EV71 infection | The role of Misshapen NCK-related kinase (MINK), a novel Ste20 family kinase, in the IRES-mediated protein translation of human enterovirus 71.
Leong SY, Ong BK, Chu JJ., Free PMC Article | 01/30/2016 |
| Misshapen-like kinase 1 (MINK1) is a novel component of striatin-interacting phosphatase and kinase (STRIPAK) and is required for the completion of cytokinesis. | Misshapen-like kinase 1 (MINK1) is a novel component of striatin-interacting phosphatase and kinase (STRIPAK) and is required for the completion of cytokinesis.
Hyodo T, Ito S, Hasegawa H, Asano E, Maeda M, Urano T, Takahashi M, Hamaguchi M, Senga T., Free PMC Article | 10/20/2012 |
| MINK1 interacts with and phosphorylates PRICKLE1 and PRICKLE2. | Mink1 regulates β-catenin-independent Wnt signaling via Prickle phosphorylation.
Daulat AM, Luu O, Sing A, Zhang L, Wrana JL, McNeill H, Winklbauer R, Angers S., Free PMC Article | 02/18/2012 |
| MINK interaction with Rap2 plays a critical role in maintaining the morphological integrity of dendrites and synaptic transmission. | MINK and TNIK differentially act on Rap2-mediated signal transduction to regulate neuronal structure and AMPA receptor function.
Hussain NK, Hsin H, Huganir RL, Sheng M., Free PMC Article | 12/11/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesMolecular genetic analysis of long QT syndrome in Norway indicating a high prevalence of heterozygous mutation carriers.
Berge KE, Haugaa KH, Früh A, Anfinsen OG, Gjesdal K, Siem G, Oyen N, Greve G, Carlsson A, Rognum TO, Hallerud M, Kongsgård E, Amlie JP, Leren TP. MinK gene polymorphism in the pathogenesis of lone atrial fibrillation.
Prystupa A, Dzida G, Myśliński W, Małaj G, Lorenc T. Analysis of minK and eNOS genes as candidate loci for predisposition to non-valvular atrial fibrillation.
Fatini C, Sticchi E, Genuardi M, Sofi F, Gensini F, Gori AM, Lenti M, Michelucci A, Abbate R, Gensini GF. | 03/13/2008 |
| Analysis of the coding region of the NIK gene in progressive supranuclear palsy (PSP) patients through single strand conformation polymorphism and direct sequencing does not support a pathogenic role of the NIK gene in PSP. | Mutational study of the nuclear factor kappa B inducing kinase gene in patients with progressive supranuclear palsy.
Campdelacreu J, Ezquerra M, Muñoz E, Oliva R, Tolosa E. | 01/21/2010 |
| results suggest that human Misshapen/NIKs-related kinase beta (hMINK beta) plays an important role in cytoskeleton reorganization, cell adhesion, and cell motility(hMINKbeta) | Identification and functional characterization of a novel human misshapen/Nck interacting kinase-related kinase, hMINK beta.
Hu Y, Leo C, Yu S, Huang BC, Wang H, Shen M, Luo Y, Daniel-Issakani S, Payan DG, Xu X. | 01/21/2010 |