| The impact of wound-healing assay, phorbol myristate acetate (PMA) stimulation and siRNA-mediated FURIN gene silencing on endogenous retroviral ERVW-1 expression level in U87-MG astrocytoma cells. | The impact of wound-healing assay, phorbol myristate acetate (PMA) stimulation and siRNA-mediated FURIN gene silencing on endogenous retroviral ERVW-1 expression level in U87-MG astrocytoma cells.
Machnik G, Bułdak Ł, Zapletal-Pudełko K, Grabarek BO, Staszkiewicz R, Sobański D, Okopień B. | 05/23/2024 |
| Novel genetic association of the Furin gene polymorphism rs1981458 with COVID-19 severity among Indian populations. | Novel genetic association of the Furin gene polymorphism rs1981458 with COVID-19 severity among Indian populations.
Pandey RK, Srivastava A, Mishra RK, Singh PP, Chaubey G., Free PMC Article | 04/8/2024 |
| Pathological changes in oral epithelium and the expression of SARS-CoV-2 entry receptors, ACE2 and furin. | Pathological changes in oral epithelium and the expression of SARS-CoV-2 entry receptors, ACE2 and furin.
Grinstein-Koren O, Lusthaus M, Tabibian-Keissar H, Kaplan I, Buchner A, Ilatov R, Vered M, Zlotogorski-Hurvitz A., Free PMC Article | 03/20/2024 |
| The subtilisin-like protease furin regulates hemin-induced CD63 surface expression on platelets. | The subtilisin-like protease furin regulates hemin-induced CD63 surface expression on platelets.
Dicenta V, Pelzer A, Laspa Z, Castor T, Gawaz MP, Rohlfing AK. | 02/23/2024 |
| An Overview of the Role of Furin in Type 2 Diabetes. | An Overview of the Role of Furin in Type 2 Diabetes.
Marafie SK, Al-Mulla F., Free PMC Article | 11/28/2023 |
| Allele-Specific Epigenetic Regulation of FURIN Expression at a Coronary Artery Disease Susceptibility Locus. | Allele-Specific Epigenetic Regulation of FURIN Expression at a Coronary Artery Disease Susceptibility Locus.
Yang W, Cao J, McVey DG, Ye S., Free PMC Article | 09/11/2023 |
| Overexpression of the pro-protein convertase furin predicts prognosis and promotes papillary thyroid carcinoma progression and metastasis through RAF/MEK signaling. | Overexpression of the pro-protein convertase furin predicts prognosis and promotes papillary thyroid carcinoma progression and metastasis through RAF/MEK signaling.
Poyil PK, Siraj AK, Padmaja D, Parvathareddy SK, Diaz R, Thangavel S, Begum R, Haqawi W, Al-Mohanna FH, Al-Sobhi SS, Al-Dayel F, Al-Kuraya KS., Free PMC Article | 07/7/2023 |
| PCSK3 Overexpression in Sjogren's Syndrome Patients May Be Regulated by rs4932178 SNP in Its Promoter Region and Correlates with IFN-gamma Gene Expression. | PCSK3 Overexpression in Sjögren's Syndrome Patients May Be Regulated by rs4932178 SNP in Its Promoter Region and Correlates with IFN-γ Gene Expression.
Latini A, De Benedittis G, Colafrancesco S, Perricone C, Novelli G, Novelli L, Priori R, Ciccacci C, Borgiani P., Free PMC Article | 06/2/2023 |
| Proprotein Convertase Furin Regulates Melanogenesis via the Notch Signaling Pathway. | Proprotein Convertase Furin Regulates Melanogenesis via the Notch Signaling Pathway.
Luo L, Jia W, Zhang Y, Guo Y, Zhu J, Li C. | 05/8/2023 |
| FURIN suppresses the progression of atherosclerosis by promoting macrophage autophagy. | FURIN suppresses the progression of atherosclerosis by promoting macrophage autophagy.
Chen H, Zhang L, Mi S, Wang H, Wang C, Jia W, Gong L, Dong H, Xu B, Jing Y, Ge P, Pei Z, Zhong L, Yang J. | 04/26/2023 |
| Proteolytic activation of human-specific Olduvai domains by the furin protease. | Proteolytic activation of human-specific Olduvai domains by the furin protease.
Pacheco A, Issaian A, Davis J, Anderson N, Nemkov T, Paukovich N, Henen MA, Vögeli B, Sikela JM, Hansen K., Free PMC Article | 03/24/2023 |
| SERPINB8 and furin regulate ITGAX expression and affect the proliferation and invasion of melanoma cells. | SERPINB8 and furin regulate ITGAX expression and affect the proliferation and invasion of melanoma cells.
Ni L, Li P, Li M, Huang S, Dang N. | 01/14/2023 |
| Loss of hypothalamic Furin affects POMC to proACTH cleavage and feeding behavior in high-fat diet-fed mice. | Loss of hypothalamic Furin affects POMC to proACTH cleavage and feeding behavior in high-fat diet-fed mice.
Coppola I, Brouwers B, Walker L, Alar C, Meulemans S, White A, Ramos-Molina B, Creemers JWM., Free PMC Article | 01/14/2023 |
| Proprotein convertase furin is a driver and potential therapeutic target in proliferative diabetic retinopathy. | Proprotein convertase furin is a driver and potential therapeutic target in proliferative diabetic retinopathy.
Abu El-Asrar AM, Nawaz MI, Ahmad A, Siddiquei MM, Allegaert E, Gikandi PW, De Hertogh G, Opdenakker G. | 08/13/2022 |
| The positive feedback loop of furin and TGFbeta1 enhances the immune responses of Tregs to hepatocellular carcinoma cells and hepatitis B virus in vitro. | The positive feedback loop of furin and TGFβ1 enhances the immune responses of Tregs to hepatocellular carcinoma cells and hepatitis B virus in vitro.
Qiu H, Wang N, Lin D, Yuan Y, Li J, Mao D, Meng Y. | 08/6/2022 |
| FURIN correlated with immune infiltration serves as a potential biomarker in SARS-CoV-2 infection-related lung adenocarcinoma. | FURIN correlated with immune infiltration serves as a potential biomarker in SARS-CoV-2 infection-related lung adenocarcinoma.
Luo L, Li M, Su J, Yao X, Luo H., Free PMC Article | 08/6/2022 |
| FURIN gene variants (rs6224/rs4702) as potential markers of death and cardiovascular traits in severe COVID-19. | FURIN gene variants (rs6224/rs4702) as potential markers of death and cardiovascular traits in severe COVID-19.
Coto E, Albaiceta GM, Amado-Rodríguez L, García-Clemente M, Cuesta-Llavona E, Vázquez-Coto D, Alonso B, Iglesias S, Melón S, Alvarez-Argüelles ME, Boga JA, Rojo-Alba S, Pérez-Oliveira S, Alvarez V, Gómez J., Free PMC Article | 06/18/2022 |
| Systematic Investigation of SARS-CoV-2 Receptor Protein Distribution along Viral Entry Routes in Humans. | Systematic Investigation of SARS-CoV-2 Receptor Protein Distribution along Viral Entry Routes in Humans.
Bräutigam K, Reinhard S, Galván JA, Wartenberg M, Hewer E, Schürch CM., Free PMC Article | 06/11/2022 |
| FURIN Promoter Methylation Predicts the Risk of Incident Diabetes: A Prospective Analysis in the Gusu Cohort. | FURIN Promoter Methylation Predicts the Risk of Incident Diabetes: A Prospective Analysis in the Gusu Cohort.
He Y, Li Y, Zhang J, Chen L, Li J, Zhang M, Zhang Q, Lu Y, Jiang J, Zhang X, Hu J, Ding Y, Zhang M, Peng H., Free PMC Article | 04/23/2022 |
| Expression profile of SARS-CoV-2 cellular entry proteins in normal oral mucosa and oral squamous cell carcinoma. | Expression profile of SARS-CoV-2 cellular entry proteins in normal oral mucosa and oral squamous cell carcinoma.
Sapkota D, Sharma S, Søland TM, Braz-Silva PH, Teh MT., Free PMC Article | 04/2/2022 |
| Circ_FURIN knockdown assuages Testosterone-induced human ovarian granulosa-like tumor cell disorders by sponging miR-423-5p to reduce MTM1 expression in polycystic ovary syndrome. | Circ_FURIN knockdown assuages Testosterone-induced human ovarian granulosa-like tumor cell disorders by sponging miR-423-5p to reduce MTM1 expression in polycystic ovary syndrome.
Xu X, Guan R, Gong K, Xie H, Shi L., Free PMC Article | 03/26/2022 |
| Spread of Gamma (P.1) Sub-Lineages Carrying Spike Mutations Close to the Furin Cleavage Site and Deletions in the N-Terminal Domain Drives Ongoing Transmission of SARS-CoV-2 in Amazonas, Brazil. | Spread of Gamma (P.1) Sub-Lineages Carrying Spike Mutations Close to the Furin Cleavage Site and Deletions in the N-Terminal Domain Drives Ongoing Transmission of SARS-CoV-2 in Amazonas, Brazil.
Naveca FG, Nascimento V, Souza V, Corado AL, Nascimento F, Silva G, Mejía MC, Brandão MJ, Costa Á, Duarte D, Pessoa K, Jesus M, Gonçalves L, Fernandes C, Mattos T, Abdalla L, Santos JH, Martins A, Chui FM, Val FF, de Melo GC, Xavier MS, Sampaio VS, Mourão MP, Lacerda MV, Batista ÉLR, Magalhães ALÁ, Dábilla N, Pereira LCG, Vinhal F, Miyajima F, Dias FBS, Dos Santos ER, Coêlho D, Ferraz M, Lins R, Wallau GL, Delatorre E, Gräf T, Siqueira MM, Resende PC, Bello G, Fiocruz COVID-19 Genomic Surveillance Network., Free PMC Article | 03/5/2022 |
| Effect of FURIN SNP rs17514846 on coronary atherosclerosis in human cardiac specimens: An autopsy study of 106 cases. | Effect of FURIN SNP rs17514846 on coronary atherosclerosis in human cardiac specimens: An autopsy study of 106 cases.
Yamasaki G, Sakurada M, Kitagawa K, Kondo T, Takahashi M, Ueno Y. | 02/19/2022 |
| Knockdown of circ-FURIN suppresses the proliferation and induces apoptosis of granular cells in polycystic ovary syndrome via miR-195-5p/BCL2 axis. | Knockdown of circ-FURIN suppresses the proliferation and induces apoptosis of granular cells in polycystic ovary syndrome via miR-195-5p/BCL2 axis.
Chen Y, Miao J, Lou G., Free PMC Article | 02/19/2022 |
| A second functional furin site in the SARS-CoV-2 spike protein. | A second functional furin site in the SARS-CoV-2 spike protein.
Zhang Y, Zhang L, Wu J, Yu Y, Liu S, Li T, Li Q, Ding R, Wang H, Nie J, Cui Z, Wang Y, Huang W, Wang Y., Free PMC Article | 01/22/2022 |