| Serum osteoglycin is stable during various glycemic challenges in healthy men. | Serum osteoglycin is stable during various glycemic challenges in healthy men.
Starup-Linde J, Westberg-Rasmussen S, Viggers R, Al-Mashhadi ZK, Handberg A, Vestergaard P, Gregersen S., Free PMC Article | 08/12/2024 |
| Osteoglycin (OGN) promotes tumorigenesis of pancreatic cancer cell via targeting ID4. | Osteoglycin (OGN) promotes tumorigenesis of pancreatic cancer cell via targeting ID4.
Qin W, Zhang J, Rong R, Zhang L, Gao H, Liu C, Ren Q, Zheng G, Wang J, Meng L, Qiao S, Qian R, Zhou C, Wang H, Zhang Y. | 10/1/2022 |
| Increased proteolytic cleavage of osteoglycin is associated with a stable plaque phenotype and lower risk of cardiovascular events. | Increased proteolytic cleavage of osteoglycin is associated with a stable plaque phenotype and lower risk of cardiovascular events.
Al-Sharify D, Nielsen SH, Matthes F, Tengryd C, Sun J, Genovese F, Karsdal MA, Nilsson J, Goncalves I, Edsfeldt A. | 09/17/2022 |
| Chrysophanol inhibits the osteoglycin/mTOR and activats NF2 signaling pathways to reduce viability and proliferation of malignant meningioma cells. | Chrysophanol inhibits the osteoglycin/mTOR and activats NF2 signaling pathways to reduce viability and proliferation of malignant meningioma cells.
Wang J, Lv P., Free PMC Article | 11/22/2021 |
| Differential expression of Lumican, Mimecan, Annexin A5 and Serotransferrin in ectopic and matched eutopic endometrium in ovarian endometriosis: a case-control study. | Differential expression of Lumican, Mimecan, Annexin A5 and Serotransferrin in ectopic and matched eutopic endometrium in ovarian endometriosis: a case-control study.
Sahar T, Nigam A, Anjum S, Waziri F, Jain SK, Wajid S. | 10/23/2021 |
| The proteoglycan mimecan is associated with carotid plaque vulnerability and increased risk of future cardiovascular death. | The proteoglycan mimecan is associated with carotid plaque vulnerability and increased risk of future cardiovascular death.
Tengryd C, Nielsen SH, Cavalera M, Bengtsson E, Genovese F, Karsdal M, Dunér P, Orho-Melander M, Nilsson J, Edsfeldt A, Gonçalves I. | 08/14/2021 |
| Osteoglycin knockdown promotes vascular smooth muscle cell proliferation and migration in aortic dissection via the VEGF/VEGFR2 axis. | Osteoglycin knockdown promotes vascular smooth muscle cell proliferation and migration in aortic dissection via the VEGF/VEGFR2 axis.
Wang Z, Zhuang X, Chen B, Wei M. | 04/17/2021 |
| Overexpressed microRNA-140 inhibits pulmonary fibrosis in interstitial lung disease via the Wnt signaling pathway by downregulating osteoglycin. | Overexpressed microRNA-140 inhibits pulmonary fibrosis in interstitial lung disease via the Wnt signaling pathway by downregulating osteoglycin.
Shi S, Li H. | 12/19/2020 |
| Circular RNA hsa_circ_0076906 competes with OGN for miR-1305 biding site to alleviate the progression of osteoporosis. | Circular RNA hsa_circ_0076906 competes with OGN for miR-1305 biding site to alleviate the progression of osteoporosis.
Wen J, Guan Z, Yu B, Guo J, Shi Y, Hu L. | 12/5/2020 |
| serum concentration not associated with carotid atherosclerosis plaque in essential hypertensive patients | Association of SLRPs with carotid artery atherosclerosis in essential hypertensive patients.
Yang Y, Wu QH, Li Y, Gao PJ. | 10/26/2019 |
| There is a positive association between OGN level and prolonged survival in CRC. OGN plays a restrictive role in colorectal cancer progression by reduced activation of EGFR/AKT/Zeb-1. | Osteoglycin (OGN) reverses epithelial to mesenchymal transition and invasiveness in colorectal cancer via EGFR/Akt pathway.
Hu X, Li YQ, Li QG, Ma YL, Peng JJ, Cai SJ., Free PMC Article | 05/11/2019 |
| High Plasma Osteoglycin expression is associated with Coronary Lesions. | Low Levels of Plasma Osteoglycin in Patients with Complex Coronary Lesions.
Seki T, Saita E, Kishimoto Y, Ibe S, Miyazaki Y, Miura K, Ohmori R, Ikegami Y, Kondo K, Momiyama Y., Free PMC Article | 02/16/2019 |
| OGN expression is positively associated with CD8+ cell density in colorectal cancer tissue, suggesting a possible influence of OGN expression on tumor reactive T cells in the tumor niche. | Osteoglycin-induced VEGF Inhibition Enhances T Lymphocytes Infiltrating in Colorectal Cancer.
Hu X, Li YQ, Li QG, Ma YL, Peng JJ, Cai SJ., Free PMC Article | 12/22/2018 |
| Results provide evidence that osteoglycin expression is increased in the heart in response to pressure overload and its absence results in increased cardiac inflammation and fibrosis resulting in increased diastolic dysfunction. | Osteoglycin prevents the development of age-related diastolic dysfunction during pressure overload by reducing cardiac fibrosis and inflammation.
Deckx S, Heggermont W, Carai P, Rienks M, Dresselaers T, Himmelreich U, van Leeuwen R, Lommen W, van der Velden J, Gonzalez A, Diez J, Papageorgiou AP, Heymans S. | 12/22/2018 |
| OGN identified as a novel oncogene in meningioma proliferation. | The emerging roles of phosphatases in Hedgehog pathway.
Zhao L, Wang L, Chi C, Lan W, Su Y., Free PMC Article | 05/26/2018 |
| serum osteoglycin is a potential predictor of adverse outcomes in patients with chronic kidney disease. | Higher Serum Levels of Osteoglycin Are Associated with All-Cause Mortality and Cardiovascular and Cerebrovascular Events in Patients with Advanced Chronic Kidney Disease.
Baek SH, Cha RH, Kang SW, Park CW, Cha DR, Kim SG, Yoon SA, Kim S, Han SY, Park JH, Chang JH, Lim CS, Kim YS, Na KY. | 05/19/2018 |
| NK cells promote fetal development through the secretion of growth-promoting factors, pleiotrophin and osteoglycin. | Natural Killer Cells Promote Fetal Development through the Secretion of Growth-Promoting Factors.
Fu B, Zhou Y, Ni X, Tong X, Xu X, Dong Z, Sun R, Tian Z, Wei H. | 12/30/2017 |
| Increased serum mimecan is associated with poor angiographic coronary collateralization in patients with chronic total occlusion | Association of serum mimecan with angiographic coronary collateralization in patients with stable coronary artery disease and chronic total occlusion.
Shen Y, Ding FH, Zhang RY, Zhang Q, Lu L, Shen WF. | 12/23/2017 |
| the association of serum OGN and FAM5C levels and muscle mass with bone mineral density (BMD), bone turnover markers, and the presence of vertebral fractures (VFs) in 156 postmenopausal women with type 2 diabetes mellitus, is reported. | Association of osteoglycin and FAM5C with bone turnover markers, bone mineral density, and vertebral fractures in postmenopausal women with type 2 diabetes mellitus.
Tanaka KI, Kanazawa I, Kaji H, Sugimoto T. | 12/23/2017 |
| OGN plays a critical role in negatively regulating ischaemia-induced angiogenesis by inhibiting VEGF-VEGFR2 signalling and thereby attenuating endothelial cells tube formation, proliferation, and migration. | Loss of osteoglycin promotes angiogenesis in limb ischaemia mouse models via modulation of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 signalling pathway.
Wu QH, Ma Y, Ruan CC, Yang Y, Liu XH, Ge Q, Kong LR, Zhang JW, Yan C, Gao PJ. | 10/7/2017 |
| The current study discovered a novel 72-kDa chondroitin sulfate-OGN that is specific for innate immune cells. This variant is able to bind and activate TLR4. | A novel 72-kDa leukocyte-derived osteoglycin enhances the activation of toll-like receptor 4 and exacerbates cardiac inflammation during viral myocarditis.
Rienks M, Papageorgiou A, Wouters K, Verhesen W, Leeuwen RV, Carai P, Summer G, Westermann D, Heymans S., Free PMC Article | 08/19/2017 |
| mimecan is a satiety hormone in adipose tissue, and that mimecan inhibits food intake independently of leptin signaling by inducing IL-1beta and IL-6 expression in the hypothalamus. | Mimecan, a Hormone Abundantly Expressed in Adipose Tissue, Reduced Food Intake Independently of Leptin Signaling.
Cao HM, Ye XP, Ma JH, Jiang H, Li SX, Li RY, Li XS, Guo CC, Wang ZQ, Zhan M, Zuo CL, Pan CM, Zhao SX, Zheng CX, Song HD., Free PMC Article | 11/5/2016 |
| Increased plasma mimecan levels are independently associated with increased arterial stiffness in hypertensive patients. | Serum Mimecan Is Associated With Arterial Stiffness in Hypertensive Patients.
Gu X, Zhao L, Zhu J, Gu H, Li H, Wang L, Xu W, Chen J., Free PMC Article | 04/23/2016 |
| OIF may be an indicator of the earlier-stage diabetic nephropathy in subjects with type 2 diabetes mellitus | Osteoinductive factor is a novel biomarker for the diagnosis of early diabetic nephropathy.
Wang S, Wang Y, Zheng R, Zhao Z, Ma Y., Free PMC Article | 04/2/2016 |
| OGN might play a role in the development of Ovarian Cancer, and may be a therapeutic target in OC. | Screening the molecular targets of ovarian cancer based on bioinformatics analysis.
Du L, Qian X, Dai C, Wang L, Huang D, Wang S, Shen X. | 10/24/2015 |