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    MIR379 microRNA 379 [ Homo sapiens (human) ]

    Gene ID: 494328, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Regulation and tumor-suppressive function of the miR-379/miR-656 (C14MC) cluster in cervical cancer.

    Regulation and tumor-suppressive function of the miR-379/miR-656 (C14MC) cluster in cervical cancer.
    Srinath S, Jishnu PV, Varghese VK, Shukla V, Adiga D, Mallya S, Chakrabarty S, Sharan K, Pandey D, Chatterjee A, Kabekkodu SP., Free PMC Article

    06/18/2024
    miR-379-5P INHIBITION ENHANCES INTESTINAL EPITHELIAL PROLIFERATION AND BARRIER FUNCTION RECOVERY AFTER ISCHEMIA/REPERFUSION BY TARGETING EIF4G2.

    miR-379-5P INHIBITION ENHANCES INTESTINAL EPITHELIAL PROLIFERATION AND BARRIER FUNCTION RECOVERY AFTER ISCHEMIA/REPERFUSION BY TARGETING EIF4G2.
    Jia Z, Wang Y, Gao J, Zheng M, Wang P, Zu G., Free PMC Article

    11/1/2023
    Circ_0010235 confers cisplatin resistance in lung cancer by upregulating E2F7 through absorbing miR-379-5p.

    Circ_0010235 confers cisplatin resistance in lung cancer by upregulating E2F7 through absorbing miR-379-5p.
    Wang L, Wang D, Xu Z, Qiu Y, Chen G, Tan F., Free PMC Article

    09/6/2023
    Granulosa cell-derived miR-379-5p regulates macrophage polarization in polycystic ovarian syndrome.

    Granulosa cell-derived miR-379-5p regulates macrophage polarization in polycystic ovarian syndrome.
    Salehi R, Asare-Werehene M, Wyse BA, Abedini A, Pan B, Gutsol A, Jahangiri S, Szaraz P, Burns KD, Vanderhyden B, Li J, Burger D, Librach CL, Tsang BK., Free PMC Article

    08/10/2023
    Androgen-induced exosomal miR-379-5p release determines granulosa cell fate: cellular mechanism involved in polycystic ovaries.

    Androgen-induced exosomal miR-379-5p release determines granulosa cell fate: cellular mechanism involved in polycystic ovaries.
    Salehi R, Wyse BA, Asare-Werehene M, Esfandiarinezhad F, Abedini A, Pan B, Urata Y, Gutsol A, Vinas JL, Jahangiri S, Xue K, Xue Y, Burns KD, Vanderhyden B, Li J, Osuga Y, Burger D, Tan SL, Librach CL, Tsang BK., Free PMC Article

    08/10/2023
    GRB10 is a novel factor associated with gastric cancer proliferation and prognosis.

    GRB10 is a novel factor associated with gastric cancer proliferation and prognosis.
    Ren LL, Wang ZW, Sen R, Dai ZT, Liao XH, Shen LJ., Free PMC Article

    05/30/2023
    Hsa-miR-379 down-regulates Rac1/MLK3/JNK/AP-1/Collagen I cascade reaction by targeting connective tissue growth factor in human alveolar basal epithelial A549 cells.

    Hsa-miR-379 down-regulates Rac1/MLK3/JNK/AP-1/Collagen I cascade reaction by targeting connective tissue growth factor in human alveolar basal epithelial A549 cells.
    Shan J, Wu MY, Zhang YC, Lin YJ, Cheng B, Gao YR, Liu ZH, Xu HM.

    05/12/2023
    Characterization of Adrenal miRNA-Based Dysregulations in Cushing's Syndrome.

    Characterization of Adrenal miRNA-Based Dysregulations in Cushing's Syndrome.
    Vetrivel S, Zhang R, Engel M, Oßwald A, Watts D, Chen A, Wielockx B, Sbiera S, Reincke M, Riester A., Free PMC Article

    08/6/2022
    MiR-379-5p inhibits the proliferation, migration, and invasion of breast cancer by targeting KIF4A.

    MiR-379-5p inhibits the proliferation, migration, and invasion of breast cancer by targeting KIF4A.
    Yang K, Li D, Jia W, Song Y, Sun N, Wang J, Li H, Yin C., Free PMC Article

    07/9/2022
    AKR1C3 decreased CML sensitivity to Imatinib in bone marrow microenvironment via dysregulation of miR-379-5p.

    AKR1C3 decreased CML sensitivity to Imatinib in bone marrow microenvironment via dysregulation of miR-379-5p.
    Pan D, Yang W, Zeng Y, Li W, Wang K, Zhao L, Li J, Ye Y, Guo Q.

    07/2/2022
    miR-379-5p inhibits proliferation and invasion of the endometrial cancer cells by inhibiting expression of ROR1.

    miR-379-5p inhibits proliferation and invasion of the endometrial cancer cells by inhibiting expression of ROR1.
    Liang M, Chen H, Min J.

    03/19/2022
    Blocking hsa_circ_0074027 suppressed non-small cell lung cancer chemoresistance via the miR-379-5p/IGF1 axis.

    Blocking hsa_circ_0074027 suppressed non-small cell lung cancer chemoresistance via the miR-379-5p/IGF1 axis.
    Zheng S, Wang C, Yan H, Du Y., Free PMC Article

    02/19/2022
    Quantification of microRNA editing using two-tailed RT-qPCR for improved biomarker discovery.

    Quantification of microRNA editing using two-tailed RT-qPCR for improved biomarker discovery.
    Voss G, Edsjö A, Bjartell A, Ceder Y., Free PMC Article

    12/18/2021
    MiR-379-5p targets microsomal glutathione transferase 1 (MGST1) to regulate human glioma in cell proliferation, migration and invasion and epithelial-mesenchymal transition (EMT).

    MiR-379-5p targets microsomal glutathione transferase 1 (MGST1) to regulate human glioma in cell proliferation, migration and invasion and epithelial-mesenchymal transition (EMT).
    Yang B, Xia S, Ye X, Jing W, Wu B.

    11/22/2021
    miR3795p inhibits cell proliferation and promotes cell apoptosis in nonsmall cell lung cancer by targeting betaarrestin1.

    miR‑379‑5p inhibits cell proliferation and promotes cell apoptosis in non‑small cell lung cancer by targeting β‑arrestin‑1.
    Jiang Y, Zhu P, Gao Y, Wang A., Free PMC Article

    05/15/2021
    LINC00665 promotes breast cancer progression through regulation of the miR-379-5p/LIN28B axis.

    LINC00665 promotes breast cancer progression through regulation of the miR-379-5p/LIN28B axis.
    Ji W, Diao YL, Qiu YR, Ge J, Cao XC, Yu Y., Free PMC Article

    01/16/2021
    MiR-30a and miR-379 modulate retinoic acid pathway by targeting DNA methyltransferase 3B in oral cancer.

    MiR-30a and miR-379 modulate retinoic acid pathway by targeting DNA methyltransferase 3B in oral cancer.
    Shiah SG, Hsiao JR, Chang HJ, Hsu YM, Wu GH, Peng HY, Chou ST, Kuo CC, Chang JY., Free PMC Article

    09/12/2020
    Study for the first time demonstrated that miR-379/TCF-4 (TCF7L2) might involve in the progression of laryngeal carcinoma, and miR-379 appears to serve as a novel tumor suppressor in laryngeal carcinoma.

    MicroRNA-379 inhibits laryngeal carcinoma cell proliferation and invasion through directly targeting TCF-4.
    Wei JL, Zhang L, Zhao ZM, Zhao YZ, Fu Q, Yang Y.

    06/13/2020
    circ-PITX1 exerted as a competing endogenous RNA (ceRNA) in glioblastoma by sponging miR-379-5p to elevate MAP3K2 expression

    Circular RNA circ-PITX1 promotes the progression of glioblastoma by acting as a competing endogenous RNA to regulate miR-379-5p/MAP3K2 axis.
    Lv X, Wang M, Qiang J, Guo S.

    03/28/2020
    miR379 inhibits cell proliferation and epithelialmesenchymal transition by targeting CHUK through the NFkappaB pathway in nonsmall cell lung cancer.

    miR‑379 inhibits cell proliferation and epithelial‑mesenchymal transition by targeting CHUK through the NF‑κB pathway in non‑small cell lung cancer.
    Liu B, Wang Z, Cheng S, Du L, Yin Y, Yang Z, Zhou J.

    01/11/2020
    Mir379 underexpression is associated with glioblastoma.

    Novel internal regulators and candidate miRNAs within miR-379/miR-656 miRNA cluster can alter cellular phenotype of human glioblastoma.
    Nayak S, Aich M, Kumar A, Sengupta S, Bajad P, Dhapola P, Paul D, Narta K, Purkrait S, Mehani B, Suri A, Chakraborty D, Mukhopadhyay A, Sarkar C., Free PMC Article

    10/26/2019
    These data first uncovered potentially pathogenic miR-379-5p and two novel targets PARP1 and XRCC6 in biochemical premature ovarian insufficiency.

    MicroRNA-379-5p is associate with biochemical premature ovarian insufficiency through PARP1 and XRCC6.
    Dang Y, Wang X, Hao Y, Zhang X, Zhao S, Ma J, Qin Y, Chen ZJ., Free PMC Article

    06/15/2019
    Study performed the expression analysis of miR-379/miR-656 miRNA-cluster (C14MC) in oligodendrogliomas (ODGs) and also investigated the mechanism underlying modulation of this cluster; and found significant downregulation of majority of the miRNAs. Further data from The Cancer Genome Atlas (TCGA) also confirmed the global downregulation of C14MC.

    Identification of miR-379/miR-656 (C14MC) cluster downregulation and associated epigenetic and transcription regulatory mechanism in oligodendrogliomas.
    Kumar A, Nayak S, Pathak P, Purkait S, Malgulawar PB, Sharma MC, Suri V, Mukhopadhyay A, Suri A, Sarkar C., Free PMC Article

    06/1/2019
    miR-379 as a potent tumor suppressor in breast cancer, mediated in part through regulation of COX-2. Exploiting the tumor-homing capacity of Mesenchymal stem cells while engineering the cells to secrete Extracellular vesicles enriched with miR-379 holds exciting potential as an innovative therapy for metastatic breast cancer.

    Employing mesenchymal stem cells to support tumor-targeted delivery of extracellular vesicle (EV)-encapsulated microRNA-379.
    O'Brien KP, Khan S, Gilligan KE, Zafar H, Lalor P, Glynn C, O'Flatharta C, Ingoldsby H, Dockery P, De Bhulbh A, Schweber JR, St John K, Leahy M, Murphy JM, Gallagher WM, O'Brien T, Kerin MJ, Dwyer RM.

    03/16/2019
    Low miR-379 expression is associated with Cervical Cancer.

    MicroRNA-379 Suppresses Cervical Cancer Cell Proliferation and Invasion by Directly Targeting V-crk Avian Sarcoma Virus CT10 Oncogene Homolog-Like (CRKL).
    Shi X, Xiao X, Yuan N, Zhang S, Yuan F, Wang X., Free PMC Article

    11/10/2018
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