| CSF neurogranin levels as a biomarker in Alzheimer's disease and frontotemporal lobar degeneration: a cross-sectional analysis. | CSF neurogranin levels as a biomarker in Alzheimer's disease and frontotemporal lobar degeneration: a cross-sectional analysis.
Jurasova V, Andel R, Katonova A, Veverova K, Zuntychova T, Horakova H, Vyhnalek M, Kolarova T, Matoska V, Blennow K, Hort J., Free PMC Article | 09/14/2024 |
| Neurogranin expression regulates mitochondrial function and redox balance in endothelial cells. | Neurogranin expression regulates mitochondrial function and redox balance in endothelial cells.
Jorgensen AN, Rashdan NA, Rao KNS, Delgadillo LF, Kolluru GK, Krzywanski DM, Pattillo CB, Kevil CG, Nam HW., Free PMC Article | 02/28/2024 |
| The diagnostic and prognostic value of serum neurogranin in acute ischemic stroke. | The diagnostic and prognostic value of serum neurogranin in acute ischemic stroke.
Kuşdoğan M, Vural S, Albayrak L, Çaltekin İ, Gökçen E. | 02/11/2023 |
| Increased levels of the synaptic proteins PSD-95, SNAP-25, and neurogranin in the cerebrospinal fluid of patients with Alzheimer's disease. | Increased levels of the synaptic proteins PSD-95, SNAP-25, and neurogranin in the cerebrospinal fluid of patients with Alzheimer's disease.
Kivisäkk P, Carlyle BC, Sweeney T, Quinn JP, Ramirez CE, Trombetta BA, Mendes M, Brock M, Rubel C, Czerkowicz J, Graham D, Arnold SE., Free PMC Article | 05/14/2022 |
| Brain CHID1 Expression Correlates with NRGN and CALB1 in Healthy Subjects and AD Patients. | Brain CHID1 Expression Correlates with NRGN and CALB1 in Healthy Subjects and AD Patients.
Castrogiovanni P, Sanfilippo C, Imbesi R, Maugeri G, Lo Furno D, Tibullo D, Castorina A, Musumeci G, Di Rosa M., Free PMC Article | 10/23/2021 |
| Neurogranin as a Novel Biomarker in Alzheimer's Disease. | Neurogranin as a Novel Biomarker in Alzheimer's Disease.
Agnello L, Gambino CM, Lo Sasso B, Bivona G, Milano S, Ciaccio AM, Piccoli T, La Bella V, Ciaccio M. | 10/16/2021 |
| Interrelations of Alzheimer s disease candidate biomarkers neurogranin, fatty acid-binding protein 3 and ferritin to neurodegeneration and neuroinflammation. | Interrelations of Alzheimer´s disease candidate biomarkers neurogranin, fatty acid-binding protein 3 and ferritin to neurodegeneration and neuroinflammation.
Brosseron F, Kleemann K, Kolbe CC, Santarelli F, Castro-Gomez S, Tacik P, Latz E, Jessen F, Heneka MT. | 08/28/2021 |
| The role of synaptic biomarkers in the spectrum of neurodegenerative diseases. | The role of synaptic biomarkers in the spectrum of neurodegenerative diseases.
Mazzucchi S, Palermo G, Campese N, Galgani A, Della Vecchia A, Vergallo A, Siciliano G, Ceravolo R, Hampel H, Baldacci F. | 08/21/2021 |
| Molecular forms of neurogranin in cerebrospinal fluid. | Molecular forms of neurogranin in cerebrospinal fluid.
Nazir FH, Camporesi E, Brinkmalm G, Lashley T, Toomey CE, Kvartsberg H, Zetterberg H, Blennow K, Becker B., Free PMC Article | 06/26/2021 |
| Cerebrospinal fluid levels of neurogranin in Parkinsonian disorders. | Cerebrospinal fluid levels of neurogranin in Parkinsonian disorders.
Hall S, Janelidze S, Zetterberg H, Brix B, Mattsson N, Surova Y, Blennow K, Hansson O. | 05/8/2021 |
| Neurogranin, Encoded by the Schizophrenia Risk Gene NRGN, Bidirectionally Modulates Synaptic Plasticity via Calmodulin-Dependent Regulation of the Neuronal Phosphoproteome. | Neurogranin, Encoded by the Schizophrenia Risk Gene NRGN, Bidirectionally Modulates Synaptic Plasticity via Calmodulin-Dependent Regulation of the Neuronal Phosphoproteome.
Hwang H, Szucs MJ, Ding LJ, Allen A, Ren X, Haensgen H, Gao F, Rhim H, Andrade A, Pan JQ, Carr SA, Ahmad R, Xu W., Free PMC Article | 05/1/2021 |
| NRGN, S100B and GFAP levels are significantly increased in patients with structural lesions resulting from mild traumatic brain injuries. | NRGN, S100B and GFAP levels are significantly increased in patients with structural lesions resulting from mild traumatic brain injuries.
Çevik S, Özgenç MM, Güneyk A, Evran Ş, Akkaya E, Çalış F, Katar S, Soyalp C, Hanımoğlu H, Kaynar MY. | 11/21/2020 |
| In first episode psychosis patients, levels of the synaptic marker CSF neurogranin appear unaltered. | Neurogranin as a potential synaptic marker in the cerebrospinal fluid of patients with a first episode psychosis.
Santillo AF, Lundgren S, Xu C, Orhan F, Fatouros-Bergman H, Blennow K, Zetterberg H, Portelius E, Karolinska Schizophrenia Project (KaSP) Consortium, Cervenka S, Jönsson EG, Erhardt S, Engberg G. | 08/1/2020 |
| These findings are the first to suggest an association between rs12807809 and abnormal Papez circuit function in patients with SZ. This study also implicates NRGN variation and abnormal Papez circuit function in SZ pathophysiology. | Association between NRGN gene polymorphism and resting-state hippocampal functional connectivity in schizophrenia.
Zhang Y, Gong X, Yin Z, Cui L, Yang J, Wang P, Zhou Y, Jiang X, Wei S, Wang F, Tang Y., Free PMC Article | 01/25/2020 |
| significant association between SNP rs12807809 and schizophrenia susceptibility in Caucasians but not Asians [meta-analysis] | The association between rs12807809 polymorphism in neurogranin gene and risk of schizophrenia: A meta-analysis.
Jin L, An Z, Xu B, Mu D, Fu S, Hu H, Shi Y, Luo X, Yi Q., Free PMC Article | 01/11/2020 |
| Although the 3 assays target different epitopes on neurogranin and have different calibrators, the high correlations and the similar group differences suggest that the different forms of neurogranin in CSF carry similar diagnostic information | Neurogranin as Cerebrospinal Fluid Biomarker for Alzheimer Disease: An Assay Comparison Study.
Willemse EAJ, De Vos A, Herries EM, Andreasson U, Engelborghs S, van der Flier WM, Scheltens P, Crimmins D, Ladenson JH, Vanmechelen E, Zetterberg H, Fagan AM, Blennow K, Bjerke M, Teunissen CE. | 10/5/2019 |
| These data support that CSF Ng is increased specifically in Alzheimer disease, that high CSF Ng concentrations likely reflect synaptic dysfunction and that CSF Ng is associated with beta-amyloid plaque pathology. | Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology.
Portelius E, Olsson B, Höglund K, Cullen NC, Kvartsberg H, Andreasson U, Zetterberg H, Sandelius Å, Shaw LM, Lee VMY, Irwin DJ, Grossman M, Weintraub D, Chen-Plotkin A, Wolk DA, McCluskey L, Elman L, McBride J, Toledo JB, Trojanowski JQ, Blennow K., Free PMC Article | 09/21/2019 |
| This study, cross-sectional analysis showed that high CSF Ng was significantly associated with lower memory scores in pooled participants with NC and MCI. | Neurogranin as a predictor of memory and executive function decline in MCI patients.
Headley A, De Leon-Benedetti A, Dong C, Levin B, Loewenstein D, Camargo C, Rundek T, Zetterberg H, Blennow K, Wright CB, Sun X, Alzheimer's Disease Neuroimaging Initiative., Free PMC Article | 07/27/2019 |
| The dynamics of calmodulin interactions with neurogranin and Ca(2+) /CAMKII alpha proteins has been reported. | Biophysical analysis of the dynamics of calmodulin interactions with neurogranin and Ca(2+) /calmodulin-dependent kinase II.
Seeger C, Talibov VO, Danielson UH., Free PMC Article | 04/7/2018 |
| Plasma neurogranin did not correlate with stroke severity. | Neurogranin and tau in cerebrospinal fluid and plasma of patients with acute ischemic stroke.
De Vos A, Bjerke M, Brouns R, De Roeck N, Jacobs D, Van den Abbeele L, Guldolf K, Zetterberg H, Blennow K, Engelborghs S, Vanmechelen E., Free PMC Article | 03/24/2018 |
| Study observed an association of rs12807809 with schizophrenia in a South Indian population. This study contributes toward the establishment of neurogranin as a susceptibility gene for schizophrenia South Indian Population. | Minor allele C of rs12807809 polymorphism in NRGN contributes to the severity of psychosis in patients with Schizophrenia in South Indian population.
Sudesh R, Priyadarshini T, Preeti R, John S, Thara R, Mowry B, Munirajan AK. | 03/10/2018 |
| associations of neuromodulin and neurogranin to Alzheimer's disease | CSF profiling of the human brain enriched proteome reveals associations of neuromodulin and neurogranin to Alzheimer's disease.
Remnestål J, Just D, Mitsios N, Fredolini C, Mulder J, Schwenk JM, Uhlén M, Kultima K, Ingelsson M, Kilander L, Lannfelt L, Svenningsson P, Nellgård B, Zetterberg H, Blennow K, Nilsson P, Häggmark-Månberg A., Free PMC Article | 09/23/2017 |
| The results of this results showed that increased CSF neurogranin levels in Alzheimer Disease. | Diagnostic and Prognostic Utility of the Synaptic Marker Neurogranin in Alzheimer Disease.
Tarawneh R, D'Angelo G, Crimmins D, Herries E, Griest T, Fagan AM, Zipfel GJ, Ladenson JH, Morris JC, Holtzman DM., Free PMC Article | 05/27/2017 |
| Polymorphisms in NRGN are associated with schizophrenia, major depressive disorder and bipolar disorder in the Han Chinese population. | Polymorphisms in NRGN are associated with schizophrenia, major depressive disorder and bipolar disorder in the Han Chinese population.
Wen Z, Chen J, Khan RA, Wang M, Song Z, Li Z, Shen J, Li W, Shi Y. | 10/1/2016 |
| Neurogranin and YKL-40 are promising AD biomarkers, independent of and complementary to the established core Alzheimer's disease (AD) biomarkers, reflecting additional pathological changes in the course of AD | Neurogranin and YKL-40: independent markers of synaptic degeneration and neuroinflammation in Alzheimer's disease.
Hellwig K, Kvartsberg H, Portelius E, Andreasson U, Oberstein TJ, Lewczuk P, Blennow K, Kornhuber J, Maler JM, Zetterberg H, Spitzer P., Free PMC Article | 09/24/2016 |