| Exploiting branched-chain amino acid metabolism and NOTCH3 expression to predict and target colorectal cancer progression. | Exploiting branched-chain amino acid metabolism and NOTCH3 expression to predict and target colorectal cancer progression.
Shen K, Zhu C, Wu J, Yan J, Li P, Cao S, Zhou X, Yao G., Free PMC Article | 11/12/2024 |
| Clinical and neuroradiological spectrum of biallelic variants in NOTCH3. | Clinical and neuroradiological spectrum of biallelic variants in NOTCH3.
Iruzubieta P, Alves CAPF, Al Shamsi AM, ElGhazali G, Zaki MS, Pinelli L, Lopergolo D, Cho BPH, Jolly AA, Al Futaisi A, Al-Amrani F, Galli J, Fazzi E, Vulin K, Barajas-Olmos F, Hengel H, Aljamal BM, Nasr V, Assarzadegan F, Ragno M, Trojano L, Ojeda NM, Çakar A, Bianchi S, Pescini F, Poggesi A, Al Tenalji A, Aziz M, Mohammad R, Chedrawi A, De Stefano N, Zifarelli G, Schöls L, Haack TB, Rebelo A, Zuchner S, Koc F, Griffiths LR, Orozco L, Helmes KG, Babaei M, Bauer P, Chan Jeong W, Karimiani EG, Schmidts M, Gleeson JG, Chung WK, Alkuraya FS, Shalbafan B, Markus HS, Houlden H, Maroofian R., Free PMC Article | 09/23/2024 |
| NOTCH3 p.Arg1231Cys is markedly enriched in South Asians and associated with stroke. | NOTCH3 p.Arg1231Cys is markedly enriched in South Asians and associated with stroke.
Rodriguez-Flores JL, Khalid S, Parikshak N, Rasheed A, Ye B, Kapoor M, Backman J, Sepehrband F, Gioia SAD, Gelfman S, De T, Banerjee N, Sharma D, Martinez H, Castaneda S, D'Ambrosio D, Zhang XA, Xun P, Tsai E, Tsai IC, Regeneron Genetics Center, Khan MZ, Jahanzaib M, Mian MR, Liaqat MB, Mahmood K, Salam TU, Hussain M, Iqbal J, Aslam F, Cantor MN, Tzoneva G, Overton J, Marchini J, Reid JG, Baras A, Verweij N, Lotta LA, Coppola G, Karalis K, Economides A, Fazio S, Liedtke W, Danesh J, Kamal A, Frossard P, Coleman T, Shuldiner AR, Saleheen D., Free PMC Article | 09/19/2024 |
| Pro-Hemorrhagic Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Associated with NOTCH3 p.R75P Mutation with Low Vascular NOTCH3 Aggregation Property. | Pro-Hemorrhagic Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Associated with NOTCH3 p.R75P Mutation with Low Vascular NOTCH3 Aggregation Property.
Ishiyama H, Kim H, Saito S, Takeda S, Takegami M, Yamamoto Y, Abe S, Nakazawa S, Tanaka T, Washida K, Morita Y, Oh ST, Jung HJ, Choi JC, Nakaoku Y, Nakahara J, Koga M, Toyoda K, Amemiya K, Ikeda Y, Hatakeyama K, Mizuta I, Mizuno T, Kim KK, Ihara M. | 09/2/2024 |
| Phenotypes Associated with NOTCH3 Cysteine-Sparing Mutations in Patients with Clinical Suspicion of CADASIL: A Systematic Review. | Phenotypes Associated with NOTCH3 Cysteine-Sparing Mutations in Patients with Clinical Suspicion of CADASIL: A Systematic Review.
Cao Y, Zhang DD, Han F, Jiang N, Yao M, Zhu YC., Free PMC Article | 08/31/2024 |
| Mutant NOTCH3ECD Triggers Defects in Mitochondrial Function and Mitophagy in CADASIL Cell Models. | Mutant NOTCH3ECD Triggers Defects in Mitochondrial Function and Mitophagy in CADASIL Cell Models.
Wang W, Gong Z, Wang Y, Zhao Y, Lu Y, Sun R, Zhang H, Shang J, Zhang J. | 08/27/2024 |
| A NOTCH3-CXCL12-driven myeloma-tumor niche signaling axis promotes chemoresistance in multiple myeloma. | A NOTCH3-CXCL12-driven myeloma-tumor niche signaling axis promotes chemoresistance in multiple myeloma.
Sabol HM, Ashby C, Adhikari M, Anloague A, Kaur J, Khan S, Choudhury SR, Schinke C, Palmieri M, Barnes CL, Ambrogini E, Nookaew I, Delgado-Calle J., Free PMC Article | 08/15/2024 |
| Nailfold capillary measurements correlated to NOTCH3 R544C mutation in preclinical CADASIL patients. | Nailfold capillary measurements correlated to NOTCH3 R544C mutation in preclinical CADASIL patients.
Liang CM, Lee W, Chou CC, Tung H, Chen HC, Chen HM, Lee WJ, Chen YM. | 08/6/2024 |
| Single-Cell Analysis Identifies NOTCH3-Mediated Interactions between Stromal Cells That Promote Microenvironment Remodeling and Invasion in Lung Adenocarcinoma. | Single-Cell Analysis Identifies NOTCH3-Mediated Interactions between Stromal Cells That Promote Microenvironment Remodeling and Invasion in Lung Adenocarcinoma.
Xiang H, Pan Y, Sze MA, Wlodarska M, Li L, van de Mark KA, Qamar H, Moure CJ, Linn DE, Hai J, Huo Y, Clarke J, Tan TG, Ho S, Teng KW, Ramli MN, Nebozhyn M, Zhang C, Barlow J, Gustafson CE, Gornisiewicz S, Albertson TP, Korle SL, Bueno R, Moy LY, Vollmann EH, Chiang DY, Brandish PE, Loboda A., Free PMC Article | 05/7/2024 |
| Myofibrillogenesis Regulator-1 Regulates the Ubiquitin Lysosomal Pathway of Notch3 Intracellular Domain Through E3 Ubiquitin-Protein Ligase Itchy Homolog in the Metastasis of Non-Small Cell Lung Cancer. | Myofibrillogenesis Regulator-1 Regulates the Ubiquitin Lysosomal Pathway of Notch3 Intracellular Domain Through E3 Ubiquitin-Protein Ligase Itchy Homolog in the Metastasis of Non-Small Cell Lung Cancer.
Zhao W, Li Y, Cheng H, Wang M, Zhang Z, Cai M, Zhao C, Xi X, Zhao X, Zhao W, Yang Y, Shao R., Free PMC Article | 04/23/2024 |
| Association of Rare NOTCH3 Variants With Prevalent and Incident Stroke and Dementia in the General Population. | Association of Rare NOTCH3 Variants With Prevalent and Incident Stroke and Dementia in the General Population.
Wang P, Yao M, Yuan J, Han F, Zhai FF, Zhang DD, Zhou LX, Ni J, Zhang SY, Cui LY, Zhu YC., Free PMC Article | 02/21/2024 |
| NOTCH3 promotes docetaxel resistance of prostate cancer cells through regulating TUBB3 and MAPK signaling pathway. | NOTCH3 promotes docetaxel resistance of prostate cancer cells through regulating TUBB3 and MAPK signaling pathway.
Sun X, Zhang Y, Xin S, Jin L, Cao Q, Wang H, Wang K, Liu X, Tang C, Li W, Li Z, Wen X, Yang G, Guo C, Liu Z, Ye L., Free PMC Article | 02/16/2024 |
| LncRNA WWTR1-AS1 upregulates Notch3 through miR-136 to increase cancer cell stemness in cervical squamous cell carcinoma. | LncRNA WWTR1-AS1 upregulates Notch3 through miR-136 to increase cancer cell stemness in cervical squamous cell carcinoma.
Zhou X, Li Z, Li M., Free PMC Article | 02/14/2024 |
| Progress to Clarify How NOTCH3 Mutations Lead to CADASIL, a Hereditary Cerebral Small Vessel Disease. | Progress to Clarify How NOTCH3 Mutations Lead to CADASIL, a Hereditary Cerebral Small Vessel Disease.
Mizuta I, Nakao-Azuma Y, Yoshida H, Yamaguchi M, Mizuno T., Free PMC Article | 01/31/2024 |
| DLL4/Notch3/WNT5B axis mediates bidirectional prometastatic crosstalk between melanoma and lymphatic endothelial cells. | DLL4/Notch3/WNT5B axis mediates bidirectional prometastatic crosstalk between melanoma and lymphatic endothelial cells.
Alve S, Gramolelli S, Jukonen J, Juteau S, Pink A, Manninen AA, Hänninen S, Monto E, Lackman MH, Carpén O, Saharinen P, Karaman S, Vaahtomeri K, Ojala PM., Free PMC Article | 01/15/2024 |
| Notch3 restricts metastasis of breast cancers through regulation of the JAK/STAT5A signaling pathway. | Notch3 restricts metastasis of breast cancers through regulation of the JAK/STAT5A signaling pathway.
Chen MN, Fang ZX, Wu Z, Bai JW, Li RH, Wen XF, Zhang GJ, Liu J., Free PMC Article | 01/3/2024 |
| Association of NOTCH3 Variant Position With Stroke Onset and Other Clinical Features Among Patients With CADASIL. | Association of NOTCH3 Variant Position With Stroke Onset and Other Clinical Features Among Patients With CADASIL.
Cho BPH, Jolly AA, Nannoni S, Tozer D, Bell S, Markus HS., Free PMC Article | 12/28/2023 |
| The m6A reader IGF2BP3 preserves NOTCH3 mRNA stability to sustain Notch3 signaling and promote tumor metastasis in nasopharyngeal carcinoma. | The m6A reader IGF2BP3 preserves NOTCH3 mRNA stability to sustain Notch3 signaling and promote tumor metastasis in nasopharyngeal carcinoma.
Chen B, Huang R, Xia T, Wang C, Xiao X, Lu S, Chen X, Ouyang Y, Deng X, Miao J, Zhao C, Wang L., Free PMC Article | 11/30/2023 |
| The cysteine-altering p.R544C variant in the NOTCH3 gene is a probable candidate for blood pressure and relevant traits in the Taiwan Biobank. | The cysteine-altering p.R544C variant in the NOTCH3 gene is a probable candidate for blood pressure and relevant traits in the Taiwan Biobank.
Lin E, Kuo PH, Liu YL, Wang TJ, Yang AC, Tsai SJ. | 10/28/2023 |
| HIV-1 subtype B Tat enhances NOTCH3 signaling in astrocytes to mediate oxidative stress, inflammatory response, and neuronal apoptosis. | HIV-1 subtype B Tat enhances NOTCH3 signaling in astrocytes to mediate oxidative stress, inflammatory response, and neuronal apoptosis.
Gao L, Sun W, Zhang D, Shang Y, Li L, Tao W, Zhang L, Liu H. | 09/15/2023 |
| NOTCH3 C201R variant causes cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) that can be confused with early-onset Alzheimer's disease. | NOTCH3 C201R variant causes cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) that can be confused with early-onset Alzheimer's disease.
Korvatska O, Bucks SA, Yoda RA, Nolan A, Dorschner MO, Tsuang D, Jayadev S, Raskind WH, Bird TD., Free PMC Article | 09/13/2023 |
| A novel report of Cys1298Gly mutation in exon 24 of NOTCH3 gene in a Chinese family with CADASIL. | A novel report of Cys1298Gly mutation in exon 24 of NOTCH3 gene in a Chinese family with CADASIL.
Hu J, Qian J, Che Z, Tang B, Li Y, Gong Q, Lu X. | 09/6/2023 |
| Genetic spectrum and clinical features of adult leukoencephalopathies in a Chinese cohort. | Genetic spectrum and clinical features of adult leukoencephalopathies in a Chinese cohort.
Liu M, Wang Y, Shi C, Yuan Y, Li L, Zhang X, Xu Y, Yang J., Free PMC Article | 07/25/2023 |
| Notch3/Hes5 Induces Vascular Dysfunction in Hypoxia-Induced Pulmonary Hypertension Through ER Stress and Redox-Sensitive Pathways. | Notch3/Hes5 Induces Vascular Dysfunction in Hypoxia-Induced Pulmonary Hypertension Through ER Stress and Redox-Sensitive Pathways.
Morris HE, Neves KB, Nilsen M, Montezano AC, MacLean MR, Touyz RM., Free PMC Article | 07/23/2023 |
| Structural changes in NOTCH3 induced by CADASIL mutations: Role of cysteine and non-cysteine alterations. | Structural changes in NOTCH3 induced by CADASIL mutations: Role of cysteine and non-cysteine alterations.
Lee SJ, Zhang X, Wu E, Sukpraphrute R, Sukpraphrute C, Ye A, Wang MM., Free PMC Article | 07/7/2023 |