| Adding evidence to the role of NEUROG1 in congenital cranial dysinnervation disorders. | Adding evidence to the role of NEUROG1 in congenital cranial dysinnervation disorders.
Dupont J, Vieira JP, Tavares ALT, Conceição CR, Khan S, Bertoli-Avella AM, Sousa AB. | 01/22/2022 |
| NeuroD1 seemed not sufficient to induce and maintain neuronal differentiation. Induction of neuronal differentiation by overexpression of Neurog1 initiated important steps for the development of glutamatergic neurons such as the spiral ganglion neurons | Induction of neuronal-like phenotype in human mesenchymal stem cells by overexpression of Neurogenin1 and treatment with neurotrophins.
Schäck L, Budde S, Lenarz T, Krettek C, Gross G, Windhagen H, Hoffmann A, Warnecke A. | 03/25/2017 |
| mutation not found in group of children with sensorineural hearing loss | The role of transcription factors of neurosensory cells in non-syndromic sensorineural hearing loss with or without inner ear malformation.
Zhou Y, Qing J, Dong Y, Nie J, Li J, Wang C, Liu Y, Peng T, Duan M, Liu X, Xie D. | 12/17/2016 |
| Results show that neurogenin-1 and -2 drive homogeneous differentiation of human stem cells into bipolar neurons in 4 days in defined media. | Rapid neurogenesis through transcriptional activation in human stem cells.
Busskamp V, Lewis NE, Guye P, Ng AH, Shipman SL, Byrne SM, Sanjana NE, Murn J, Li Y, Li S, Stadler M, Weiss R, Church GM., Free PMC Article | 02/14/2015 |
| We propose NEUROG1 as a new gene for syndromic autosomal recessive hearing loss and congenital cranial dysinnervation disorder | A boy with homozygous microdeletion of NEUROG1 presents with a congenital cranial dysinnervation disorder [Moebius syndrome variant].
Schröder JC, Läßig AK, Galetzka D, Peters A, Castle JC, Diederich S, Zechner U, Müller-Forell W, Keilmann A, Bartsch O., Free PMC Article | 07/20/2013 |
| Methylation of NEUROG1 is associated with recurrence following adjuvant FOLFOX in Stages II/III colorectal cancer. | Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer.
Han SW, Lee HJ, Bae JM, Cho NY, Lee KH, Kim TY, Oh DY, Im SA, Bang YJ, Jeong SY, Park KJ, Park JG, Kang GH, Kim TY. | 05/11/2013 |
| NEUROG1 gene is frequently found in patients, diagnosed with colorectal cancer. | Methylation of NEUROG1 in serum is a sensitive marker for the detection of early colorectal cancer.
Herbst A, Rahmig K, Stieber P, Philipp A, Jung A, Ofner A, Crispin A, Neumann J, Lamerz R, Kolligs FT. | 08/13/2011 |
| Stable expression of a single gene Ngn1 in F3 cells induces not simply neurogenic but multifunctional changes that potentially affect the differentiation of human NSC via a reorganization of complex gene regulatory networks. | Stable expression of neurogenin 1 induces LGR5, a novel stem cell marker, in an immortalized human neural stem cell line HB1.F3.
Satoh J, Obayashi S, Tabunoki H, Wakana T, Kim SU. | 07/5/2010 |
| The basic helix-loop-helix region of human neurogenin 1 is a monomeric natively unfolded protein which forms a "fuzzy" complex upon DNA binding. | The basic helix-loop-helix region of human neurogenin 1 is a monomeric natively unfolded protein which forms a "fuzzy" complex upon DNA binding.
Aguado-Llera D, Goormaghtigh E, de Geest N, Quan XJ, Prieto A, Hassan BA, Gómez J, Neira JL. | 03/22/2010 |
| Major alleles on two NEUROG1-associated SNPs (rs2344484-C-allele and rs8192558-G-allele) were significantly more prevalent among patients. this is the first study to examine brain morphological and neurocognitive correlates of NEUROG1. | Basic helix-loop-helix transcription factor NEUROG1 and schizophrenia: effects on illness susceptibility, MRI brain morphometry and cognitive abilities.
Ho BC, Epping E, Wang K, Andreasen NC, Librant A, Wassink TH, Ho BC, Epping E, Wang K, Andreasen NC, Librant A, Wassink TH., Free PMC Articles: PMC2597152, PMC2597152 | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (4) articlesIdentification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.
Gratacòs M, Costas J, de Cid R, Bayés M, González JR, Baca-García E, de Diego Y, Fernández-Aranda F, Fernández-Piqueras J, Guitart M, Martín-Santos R, Martorell L, Menchón JM, Roca M, Sáiz-Ruiz J, Sanjuán J, Torrens M, Urretavizcaya M, Valero J, Vilella E, Estivill X, Carracedo A, Psychiatric Genetics Network Group. Basic helix-loop-helix transcription factor NEUROG1 and schizophrenia: effects on illness susceptibility, MRI brain morphometry and cognitive abilities.
Ho BC, Epping E, Wang K, Andreasen NC, Librant A, Wassink TH, Ho BC, Epping E, Wang K, Andreasen NC, Librant A, Wassink TH. Association of autism with polymorphisms in the paired-like homeodomain transcription factor 1 (PITX1) on chromosome 5q31: a candidate gene analysis.
Philippi A, Tores F, Carayol J, Rousseau F, Letexier M, Roschmann E, Lindenbaum P, Benajjou A, Fontaine K, Vazart C, Gesnouin P, Brooks P, Hager J. Association between the 5q31.1 gene neurogenin1 and schizophrenia.
Fanous AH, Chen X, Wang X, Amdur RL, O'Neill FA, Walsh D, Kendler KS, Fanous AH, Chen X, Wang X, Amdur RL, O'Neill FA, Walsh D, Kendler KS. | 03/13/2008 |
| These results, along with a priori evidence for the involvement of neurog1 in neurodevelopment, suggest that variants in neurog1 might have a small effect on susceptibility to schizophrenia. | Association between the 5q31.1 gene neurogenin1 and schizophrenia.
Fanous AH, Chen X, Wang X, Amdur RL, O'Neill FA, Walsh D, Kendler KS, Fanous AH, Chen X, Wang X, Amdur RL, O'Neill FA, Walsh D, Kendler KS. | 01/21/2010 |
| Overexpression of the full-length Ngn1 induced neurite outgrowth in F11 cells in the absence of cAMP | Overexpression of neurogenin1 induces neurite outgrowth in F11 neuroblastoma cells.
Kim S, Ghil SH, Kim SS, Myeong HH, Lee YD, Suh-Kim H. | 01/21/2010 |