| Identification and validation of N[7] -methylguanosine-associated gene NCBP1 as prognostic and immune-associated biomarkers in breast cancer patients. | Identification and validation of N(7) -methylguanosine-associated gene NCBP1 as prognostic and immune-associated biomarkers in breast cancer patients.
Li J, Zheng L, Song L, Dong Z, Bai W, Qi L., Free PMC Article | 02/8/2024 |
| Translation mediated by the nuclear cap-binding complex is confined to the perinuclear region via a CTIF-DDX19B interaction. | Translation mediated by the nuclear cap-binding complex is confined to the perinuclear region via a CTIF-DDX19B interaction.
Park Y, Park J, Hwang HJ, Kim L, Jeong K, Song HK, Rufener SC, Mühlemann O, Kim YK., Free PMC Article | 10/9/2021 |
| Affinity proteomic dissection of the human nuclear cap-binding complex interactome. | Affinity proteomic dissection of the human nuclear cap-binding complex interactome.
Dou Y, Kalmykova S, Pashkova M, Oghbaie M, Jiang H, Molloy KR, Chait BT, Rout MP, Fenyö D, Jensen TH, Altukhov I, LaCava J., Free PMC Article | 11/21/2020 |
| NCBP1 promotes the development of lung adenocarcinoma through up-regulation of CUL4B. | NCBP1 promotes the development of lung adenocarcinoma through up-regulation of CUL4B.
Zhang H, Wang A, Tan Y, Wang S, Ma Q, Chen X, He Z., Free PMC Article | 09/5/2020 |
| Results suggest that rev protein, HIV-1 (Rev) regulates the association of nuclear cap-binding protein NCBP 80 kDa subunit (CBP80) and eukaryotic translation initiation factor 4A1 (eIF4AI) with the unspliced mRNA in the cytoplasm and the nucleus, respectively, during HIV-1 replication. | A Rev-CBP80-eIF4AI complex drives Gag synthesis from the HIV-1 unspliced mRNA.
Toro-Ascuy D, Rojas-Araya B, García-de-Gracia F, Rojas-Fuentes C, Pereira-Montecinos C, Gaete-Argel A, Valiente-Echeverría F, Ohlmann T, Soto-Rifo R., Free PMC Article | 07/6/2019 |
| Study proposes the existence of an alternative cap-binding complex involving NCBP1 and NCBP3 that plays a key role in mRNA biogenesis. | mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3.
Gebhardt A, Habjan M, Benda C, Meiler A, Haas DA, Hein MY, Mann A, Mann M, Habermann B, Pichlmair A., Free PMC Article | 05/7/2016 |
| down-regulation of CTIF using a small interfering RNA causes a redistribution of CBP80 from polysome fractions to subpolysome fractions, without significant consequence to eIF4E distribution | Translation initiation on mRNAs bound by nuclear cap-binding protein complex CBP80/20 requires interaction between CBP80/20-dependent translation initiation factor and eukaryotic translation initiation factor 3g.
Choe J, Oh N, Park S, Lee YK, Song OK, Locker N, Chi SG, Kim YK., Free PMC Article | 08/18/2012 |
| Cellular processes by which CBP80-CBP20 -bound messenger ribonucleoproteins (mRNPs) are remodeled to eIF4E-bound mRNPs, are overviewed. | CBP80-promoted mRNP rearrangements during the pioneer round of translation, nonsense-mediated mRNA decay, and thereafter.
Maquat LE, Hwang J, Sato H, Tang Y., Free PMC Article | 10/8/2011 |
| Viral mRNA associates with the influenza virus A NS1 and the cellular NCBP1 of the nuclear cap-binding complex. | Cellular cap-binding proteins associate with influenza virus mRNAs.
Bier K, York A, Fodor E. | 09/3/2011 |
| UPF1 binds PTC-containing mRNA more efficiently than the corresponding PTC-free mRNA in a way that is promoted by the UPF1-CBP80 interaction. | UPF1 association with the cap-binding protein, CBP80, promotes nonsense-mediated mRNA decay at two distinct steps.
Hwang J, Sato H, Tang Y, Matsuda D, Maquat LE., Free PMC Article | 09/13/2010 |
| resolution X-ray structure for a cap-binding complex (CBC)-importin-alpha complex that provides a detailed picture for how importin-alpha binds to the CBP80 subunit of the CBC. | The molecular basis for the regulation of the cap-binding complex by the importins.
Dias SM, Wilson KF, Rojas KS, Ambrosio AL, Cerione RA., Free PMC Article | 01/21/2010 |
| a new MIF4G domain-containing protein, CTIF (CBP80/20-dependent translation initiation factor) that interacts directly with CBP80 and is part of the CBP80/20-dependent translation initiation complex | A new MIF4G domain-containing protein, CTIF, directs nuclear cap-binding protein CBP80/20-dependent translation.
Kim KM, Cho H, Choi K, Kim J, Kim BW, Ko YG, Jang SK, Kim YK., Free PMC Article | 01/21/2010 |
| The authors could distinguish two tyrosines, Y43 and Y20, in stabilization of the cap inside the cap-binding complex binding pocket. | Diverse role of three tyrosines in binding of the RNA 5' cap to the human nuclear cap binding complex.
Worch R, Jankowska-Anyszka M, Niedzwiecka A, Stepinski J, Mazza C, Darzynkiewicz E, Cusack S, Stolarski R. | 01/21/2010 |
| We show that NELF interacts with the nuclear cap binding complex (CBC), a heterodimeric, multifunctional factor that plays important roles in several mRNA processing steps, and the two factors together participate in the 3' end processing of histone mRNAs | NELF interacts with CBC and participates in 3' end processing of replication-dependent histone mRNAs.
Narita T, Yung TM, Yamamoto J, Tsuboi Y, Tanabe H, Tanaka K, Yamaguchi Y, Handa H. | 01/21/2010 |
| crystal structure at 2.1 A resolution of CBP20 and CBP80 bound to an m(7)GpppG cap analogue | Large-scale induced fit recognition of an m(7)GpppG cap analogue by the human nuclear cap-binding complex.
Mazza C, Segref A, Mattaj IW, Cusack S., Free PMC Article | 01/21/2010 |
| Association of CBC with PARN might have importance in the regulated recruitment of PARN to the nonsense-mediated decay pathway during the pioneer round of translation. | Inhibition of mRNA deadenylation by the nuclear cap binding complex (CBC).
Balatsos NA, Nilsson P, Mazza C, Cusack S, Virtanen A. | 01/21/2010 |
| Structural basis of m7GpppG binding to the nuclear cap-binding protein complex. | Structural basis of m7GpppG binding to the nuclear cap-binding protein complex.
Calero G, Wilson KF, Ly T, Rios-Steiner JL, Clardy JC, Cerione RA. | 01/21/2010 |
| During nonsense-mediated mRNA decay, CBP80 interacts with Upf1 and promotes the interaction of Upf1 with Upf2 but not with Stau1. | CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells.
Hosoda N, Kim YK, Lejeune F, Maquat LE. | 01/21/2010 |
| The organization of the CBP80-CBP20 complex suggests how the activity of eIF4G in translation initiation could be regulated through a dynamic network of overlapping intra- and intermolecular interactions. | eIF4G and CBP80 share a common origin and similar domain organization: implications for the structure and function of eIF4G.
Marintchev A, Wagner G. | 01/21/2010 |