| DNA methylation-driven gene FAM3D promotes colorectal cancer growth via the ATF4-SESN2-mTORC1 pathway. | DNA methylation-driven gene FAM3D promotes colorectal cancer growth via the ATF4-SESN2-mTORC1 pathway.
Zheng T, Zhang D, Fu Q, Wang M, Cheng Z, Cao Y, Wang L, Liu J, Zhao Y., Free PMC Article | 10/30/2024 |
| Hyperactivation of ATF4/TGF-beta1 signaling contributes to the progressive cardiac fibrosis in Arrhythmogenic cardiomyopathy caused by DSG2 Variant. | Hyperactivation of ATF4/TGF-β1 signaling contributes to the progressive cardiac fibrosis in Arrhythmogenic cardiomyopathy caused by DSG2 Variant.
Zhang B, Wu Y, Zhou C, Xie J, Zhang Y, Yang X, Xiao J, Wang DW, Shan C, Zhou X, Xiang Y, Yang B., Free PMC Article | 10/23/2024 |
| Switch of ELF3 and ATF4 transcriptional axis programs the amino acid insufficiency-linked epithelial-to-mesenchymal transition. | Switch of ELF3 and ATF4 transcriptional axis programs the amino acid insufficiency-linked epithelial-to-mesenchymal transition.
Lin J, Hou L, Zhao X, Zhong J, Lv Y, Jiang X, Ye B, Qiao Y., | 10/22/2024 |
| Signal Transducer and Activator of Transcription 4-Induced Up-Regulated LINC01278 Enhances Proliferation and Invasion of Non-Small Cell Lung Cancer Cells via the MicroRNA-877-5p/Activating Transcription Factor 4 Axis. | Signal Transducer and Activator of Transcription 4-Induced Up-Regulated LINC01278 Enhances Proliferation and Invasion of Non-Small Cell Lung Cancer Cells via the MicroRNA-877-5p/Activating Transcription Factor 4 Axis.
Yang L, Xiao Y, Deng S, Yan D, Li Z, Wang Y, Lei C., | 10/8/2024 |
| Novel insights into the activating transcription factor 4 in Alzheimer's disease and associated aging-related diseases: Mechanisms and therapeutic implications. | Novel insights into the activating transcription factor 4 in Alzheimer's disease and associated aging-related diseases: Mechanisms and therapeutic implications.
Zhang N, Nao J, Zhang S, Dong X. | 09/24/2024 |
| PTX promotes breast cancer migration and invasion by recruiting ATF4 to upregulate FGF19. | PTX promotes breast cancer migration and invasion by recruiting ATF4 to upregulate FGF19.
Xue T, Wang X, Pan X, Liu M, Xu F. | 08/31/2024 |
| Identification of a novel RNA transcript TISPL upregulated by stressors that stimulate ATF4. | Identification of a novel RNA transcript TISPL upregulated by stressors that stimulate ATF4.
Wakabayashi Y, Shimono A, Terauchi Y, Zeng C, Hamada M, Semba K, Watanabe S, Ishikawa K. | 08/5/2024 |
| ATF4 inhibits tumor development and mediates p-GCN2/ASNS upregulation in colon cancer. | ATF4 inhibits tumor development and mediates p-GCN2/ASNS upregulation in colon cancer.
Chen J, Huang X, Zhang S, Zhu X., Free PMC Article | 06/14/2024 |
| Stem-loop-induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control. | Stem-loop-induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control.
Smirnova AM, Hronová V, Mohammad MP, Herrmannová A, Gunišová S, Petráčková D, Halada P, Coufal Š, Świrski M, Rendleman J, Jendruchová K, Hatzoglou M, Beznosková P, Vogel C, Valášek LS., Free PMC Article | 04/30/2024 |
| miR-214 aggravates oxidative stress in thalassemic erythroid cells by targeting ATF4. | miR-214 aggravates oxidative stress in thalassemic erythroid cells by targeting ATF4.
Penglong T, Saensuwanna A, Jantapaso H, Phuwakanjana P, Jearawiriyapaisarn N, Paiboonsukwong K, Wanichsuwan W, Srinoun K., Free PMC Article | 04/24/2024 |
| Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4. | Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4.
Chavdoula E, Anastas V, La Ferlita A, Aldana J, Carota G, Spampinato M, Soysal B, Cosentini I, Parashar S, Sircar A, Nigita G, Sehgal L, Freitas MA, Tsichlis PN. | 04/8/2024 |
| Advanced glycation end products promote meniscal calcification by activating the mTOR-ATF4 positive feedback loop. | Advanced glycation end products promote meniscal calcification by activating the mTOR-ATF4 positive feedback loop.
Yang S, Xie J, Pan Z, Guan H, Tu Y, Ye Y, Huang S, Fu S, Li K, Huang Z, Li X, Shi Z, Li L, Zhang Y., Free PMC Article | 04/5/2024 |
| ATF4 in cellular stress, ferroptosis, and cancer. | ATF4 in cellular stress, ferroptosis, and cancer.
Tang H, Kang R, Liu J, Tang D. | 03/18/2024 |
| Gut-derived ammonia contributes to alcohol-related fatty liver development via facilitating ethanol metabolism and provoking ATF4-dependent de novo lipogenesis activation. | Gut-derived ammonia contributes to alcohol-related fatty liver development via facilitating ethanol metabolism and provoking ATF4-dependent de novo lipogenesis activation.
Song Q, Hwang CL, Li Y, Wang J, Park J, Lee SM, Sun Z, Sun J, Xia Y, Nieto N, Cordoba-Chacon J, Jiang Y, Dou X, Song Z. | 02/14/2024 |
| Endometrial stromal cell autophagy-dependent ferroptosis caused by iron overload in ovarian endometriosis is inhibited by the ATF4-xCT pathway. | Endometrial stromal cell autophagy-dependent ferroptosis caused by iron overload in ovarian endometriosis is inhibited by the ATF4-xCT pathway.
Dong X, Xu L, Wang S, Jiao X, Yan S, Huang Y, Yuan M, Wang G. | 01/17/2024 |
| The ATF4-regulated LncRNA MALAT1 promotes odontoblastic differentiation of human dental pulp stem cells via histone demethylase JMJD3: An in vitro study. | The ATF4-regulated LncRNA MALAT1 promotes odontoblastic differentiation of human dental pulp stem cells via histone demethylase JMJD3: An in vitro study.
Yu S, Guo J, Yang D, Yan X, Zhang Z, Wei P, Qiu L. | 12/26/2023 |
| Genome-wide census of ATF4 binding sites and functional profiling of trait-associated genetic variants overlapping ATF4 binding motifs. | Genome-wide census of ATF4 binding sites and functional profiling of trait-associated genetic variants overlapping ATF4 binding motifs.
Örd T, Örd D, Adler P, Örd T., Free PMC Article | 11/16/2023 |
| YAP governs cellular adaptation to perturbation of glutamine metabolism by regulating ATF4-mediated stress response. | YAP governs cellular adaptation to perturbation of glutamine metabolism by regulating ATF4-mediated stress response.
Kim M, Hwang S, Kim B, Shin S, Yang S, Gwak J, Jeong SM. | 09/18/2023 |
| The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2. | The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2.
Kreß JKC, Jessen C, Hufnagel A, Schmitz W, Xavier da Silva TN, Ferreira Dos Santos A, Mosteo L, Goding CR, Friedmann Angeli JP, Meierjohann S. | 08/3/2023 |
| ATF4 suppresses hepatocarcinogenesis by inducing SLC7A11 (xCT) to block stress-related ferroptosis. | ATF4 suppresses hepatocarcinogenesis by inducing SLC7A11 (xCT) to block stress-related ferroptosis.
He F, Zhang P, Liu J, Wang R, Kaufman RJ, Yaden BC, Karin M., Free PMC Article | 07/19/2023 |
| Activating transcription factor 4 regulates mitochondrial content, morphology, and function in differentiating skeletal muscle myotubes. | Activating transcription factor 4 regulates mitochondrial content, morphology, and function in differentiating skeletal muscle myotubes.
Memme JM, Sanfrancesco VC, Hood DA. | 06/29/2023 |
| TXLNG improves insulin resistance in obese subjects in vitro and in vivo by inhibiting ATF4 transcriptional activity. | TXLNG improves insulin resistance in obese subjects in vitro and in vivo by inhibiting ATF4 transcriptional activity.
Tao J, Gu P, Lai H, Peng H, Guo Z, Yuan Y, Yu X, Shen X, Liu J, Xier Z, Li G, Yang Y. | 05/18/2023 |
| The transcription factor ATF4 mediates endoplasmic reticulum stress-related podocyte injury and slit diaphragm defects. | The transcription factor ATF4 mediates endoplasmic reticulum stress-related podocyte injury and slit diaphragm defects.
Krausel V, Pund L, Nüsse H, Bachir H, Ricker A, Klingauf J, Weide T, Pavenstädt H, Krahn MP, Braun DA. | 04/26/2023 |
| Mechanism of miR-338-3p in sepsis-induced acute lung injury via indirectly modulating ATF4. | Mechanism of miR-338-3p in sepsis-induced acute lung injury via indirectly modulating ATF4.
Yang J, Huang Q, Liao P, Zhang P, Sun S, Xu Q. | 01/28/2023 |
| TRIB3 Mediates Fibroblast Activation and Fibrosis though Interaction with ATF4 in IPF. | TRIB3 Mediates Fibroblast Activation and Fibrosis though Interaction with ATF4 in IPF.
Wang L, Zhao W, Xia C, Li Z, Zhao W, Xu K, Wang N, Lian H, Rosas IO, Yu G., Free PMC Article | 01/11/2023 |