| Myo9b mutations are associated with altered dendritic cell functions and increased susceptibility to autoimmune diabetes onset. | Myo9b mutations are associated with altered dendritic cell functions and increased susceptibility to autoimmune diabetes onset.
Zhang J, Zou Y, Chen L, Sun F, Xu Q, Zhou Q, Wang Y, Luo X, Wang N, Li Y, Zhang S, Xiong F, Yang P, Liu S, Yang T, Weng J, Eizirik DL, Yan J, Zhou Z, Wang CY., Free PMC Article | 09/29/2023 |
| Mutations in MYO9B are associated with Charcot-Marie-Tooth disease type 2 neuropathies and isolated optic atrophy. | Mutations in MYO9B are associated with Charcot-Marie-Tooth disease type 2 neuropathies and isolated optic atrophy.
Cipriani S, Guerrero-Valero M, Tozza S, Zhao E, Vollmer V, Beijer D, Danzi M, Rivellini C, Lazarevic D, Pipitone GB, Grosz BR, Lamperti C, Marzoli SB, Carrera P, Devoto M, Pisciotta C, Pareyson D, Kennerson M, Previtali SC, Zuchner S, Scherer SS, Manganelli F, Bähler M, Bolino A., Free PMC Article | 01/21/2023 |
| Local Myo9b RhoGAP activity regulates cell motility. | Local Myo9b RhoGAP activity regulates cell motility.
Hemkemeyer SA, Vollmer V, Schwarz V, Lohmann B, Honnert U, Taha M, Schnittler HJ, Bähler M., Free PMC Article | 08/21/2021 |
| The RhoA regulators Myo9b and GEF-H1 are targets of cyclic nucleotide-dependent kinases in platelets. | The RhoA regulators Myo9b and GEF-H1 are targets of cyclic nucleotide-dependent kinases in platelets.
Comer S, Nagy Z, Bolado A, von Kriegsheim A, Gambaryan S, Walter U, Pagel O, Zahedi RP, Jurk K, Smolenski A. | 07/3/2021 |
| TSAd Plays a Major Role in Myo9b-Mediated Suppression of Malignant Pleural Effusion by Regulating TH1/TH17 Cell Response. | TSAd Plays a Major Role in Myo9b-Mediated Suppression of Malignant Pleural Effusion by Regulating T(H)1/T(H)17 Cell Response.
Yi FS, Zhang X, Zhai K, Huang ZY, Wu XZ, Wu MT, Shi XY, Pei XB, Dong SF, Wang W, Yang Y, Du J, Luo ZT, Shi HZ. | 04/17/2021 |
| Class IX Myosins: Motorized RhoGAP Signaling Molecules. | Class IX Myosins: Motorized RhoGAP Signaling Molecules.
Hanley PJ, Vollmer V, Bähler M. | 08/15/2020 |
| findings demonstrated a key role of circMYO9B/miR-4316/FOXP4 axis in regulating breast cancer progression | Circular RNA circMYO9B facilitates breast cancer cell proliferation and invasiveness via upregulating FOXP4 expression by sponging miR-4316.
Wang N, Gu Y, Li L, Wang F, Lv P, Xiong Y, Qiu X. | 07/6/2019 |
| Analysis of PTPN22, ZFAT and MYO9B polymorphisms in Turner Syndrome and risk of autoimmune disease. | Analysis of PTPN22, ZFAT and MYO9B polymorphisms in Turner Syndrome and risk of autoimmune disease.
Villanueva-Ortega E, Ahedo B, Fonseca-Sánchez MA, Pérez-Durán J, Garibay-Nieto N, Macías-Galavíz MT, Trujillo-Cabrera Y, García-Latorre E, Queipo G. | 03/31/2018 |
| data indicate that polymorphisms in MY09B are associated with the risk of inflammatory bowel disease | MYO9B gene polymorphisms are associated with the risk of inflammatory bowel diseases.
Wang MJ, Xu XL, Yao GL, Yu Q, Zhu CF, Kong ZJ, Zhao H, Tang LM, Qin XH., Free PMC Article | 02/3/2018 |
| Mutating either of the two arginine fingers impaired the catalytic activity of Myo9b-RhoGAP. | Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism.
Yi F, Kong R, Ren J, Zhu L, Lou J, Wu JY, Feng W., Free PMC Article | 06/10/2017 |
| meta-analysis indicates that MYO9B gene polymorphisms might be not associated with coeliac disease susceptibility in Caucasians. [meta-analysis] | Lack of Association between MYO9B Gene Polymorphisms and Susceptibility to Coeliac Disease in Caucasians: Evidence from a Meta-Analysis.
Chen YQ, Zhang L, Lv XY, Wang HZ. | 04/1/2017 |
| this meta-analysis shows that MYO9B genetic polymorphism is associated with Crohn's disease and ulcerative colitis | A meta-analysis of the relationship between MYO9B gene polymorphisms and susceptibility to Crohn's disease and ulcerative colitis.
Li P, Yang XK, Wang X, Zhao MQ, Zhang C, Tao SS, Zhao W, Huang Q, Li LJ, Pan HF, Ye DQ. | 03/18/2017 |
| newly defined SLIT/ROBO/Myo9b/RhoA signaling pathway that restricts lung cancer progression and metastasis. | Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression.
Kong R, Yi F, Wen P, Liu J, Chen X, Ren J, Li X, Shang Y, Nie Y, Wu K, Fan D, Zhu L, Feng W, Wu JY., Free PMC Article | 02/6/2016 |
| Our data suggest a link between MYO9B variants to an increased intestinal permeability in Crohn's disease patients. | Myosin IXb variants and their pivotal role in maintaining the intestinal barrier: a study in Crohn's disease.
Prager M, Durmus T, Büttner J, Molnar T, de Jong DJ, Drenth JP, Baumgart DC, Sturm A, Farkas K, Witt H, Büning C. | 10/17/2015 |
| Results does not support the association of MYO9B with schizophrenia in Chinese population. | Lack of genetic association between the MYO9B locus and schizophrenia in a Chinese population.
Wang J, Wang Z, Liu Y, Hui L, Du W, Zhao X, Xu Y, Zhang H, Zhao X, Zhang X. | 09/26/2015 |
| MYO9B SNPs may influence the sub-phenotypic expression of Crohn's disease but did not find an association between these MYO9B polymorphisms and intestinal permeability in IBD. | Association of MYO9B gene polymorphisms with inflammatory bowel disease in Chinese Han population.
Hu J, Mei Q, Huang J, Hu NZ, Liu XC, Xu JM., Free PMC Article | 04/18/2015 |
| Variants in MYO9B may be involved in acute pancreatitis | Association analysis of genetic variants in the myosin IXB gene in acute pancreatitis.
Nijmeijer RM, van Santvoort HC, Zhernakova A, Teller S, Scheiber JA, de Kovel CG, Besselink MG, Visser JT, Lutgendorff F, Bollen TL, Boermeester MA, Rijkers GT, Weiss FU, Mayerle J, Lerch MM, Gooszen HG, Akkermans LM, Wijmenga C, Dutch Pancreatitis Study Group., Free PMC Article | 02/28/2015 |
| genetic variation MYO9B gene is associated with celiac disease as a protective or a risk factor | Frequency of MYO9B polymorphisms in celiac patients and controls.
Loeff T, Araya M, Pérez-Bravo F. | 12/14/2013 |
| The homozygous G/G group of theMyo9B polymorphism was associated with an increased risk for Barrett's esophagus and esophageal adenocarcinoms (EAC) development. Also the heterozygous A/G genotype was associated with an increased risk for EAC development. | Myo9B is associated with an increased risk of Barrett's esophagus and esophageal adenocarcinoma.
Menke V, Van Zoest KP, Moons LM, Pot RG, Siersema PD, Kuipers EJ, Kusters JG. | 05/25/2013 |
| critical roles for Myo9b during epithelial wound healing and maintenance of tight junction integrity-key functions that may be altered in patients with Myo9b-linked inflammatory bowel disease. | A role for myosin IXb, a motor-RhoGAP chimera, in epithelial wound healing and tight junction regulation.
Chandhoke SK, Mooseker MS., Free PMC Article | 11/17/2012 |
| we performed genetic analysis of the MYO9B gene and the IL-2/IL-21 locus by genotyping SNPs that have been previously associated with coeliac disease or schizophrenia found no evidence for association with these two loci. | No association observed between schizophrenia and non-HLA coeliac disease genes: integration with the initial MYO9B association with coeliac disease.
Law MH, Bradford M, McNamara N, Gajda A, Wei J. | 02/4/2012 |
| These data demonstrate an association of MYO9B with ileal CD. | Replication of genetic variation in the MYO9B gene in Crohn's disease.
Wolters VM, Xu W, Zhao X, Walters TD, Griffiths AM, Silverberg MS, Muise AM. | 10/22/2011 |
| gene polymorphism is associated with type i diabetes in Dutch but not in Brotosh population | Association analysis of myosin IXB and type 1 diabetes.
Persengiev S, Koeleman BP, Downes K, Valdigem G, van der Slik AR, Eerligh P, Monsuur A, Bruining GJ, Wijmenga C, Todd JA, Roep BO, Alizadeh BZ. | 10/4/2010 |
| No association of MYO9B variants to multiple sclerosis (MS) in four Northern European populations | MYO9B polymorphisms in multiple sclerosis.
Kemppinen A, Suvela M, Tienari PJ, Elovaara I, Koivisto K, Pirttilä T, Reunanen M, Rautakorpi I, Hillert J, Lundmark F, Oturai A, Ryder L, Harbo HF, Celius EG, Palotie A, Daly M, Peltonen L, Saarela J., Free PMC Article | 01/21/2010 |
| MYO9B variants may be involved in inflammatory bowel disease pathogenesis | Association between genetic variants in myosin IXB and Crohn's disease.
Cooney R, Cummings JR, Pathan S, Beckly J, Geremia A, Hancock L, Guo C, Morris A, Jewell DP. | 01/21/2010 |