| Myo1e overexpression in lung adenocarcinoma is associated with increased risk of mortality. | Myo1e overexpression in lung adenocarcinoma is associated with increased risk of mortality.
Jusue-Torres I, Tiv R, Ricarte-Filho JC, Mallisetty A, Contreras-Vargas L, Godoy-Calderon MJ, Khaddour K, Kennedy K, Valyi-Nagy K, David O, Menchaca M, Kottorou A, Koutras A, Dimitrakopoulos F, Abdelhady KM, Massad M, Rubinstein I, Feldman L, Stewart J, Shimamura T, Danilova L, Hulbert A., Free PMC Article | 03/20/2023 |
| Focal segmental glomerulosclerosis and proteinuria associated with Myo1E mutations: novel variants and histological phenotype analysis. | Focal segmental glomerulosclerosis and proteinuria associated with Myo1E mutations: novel variants and histological phenotype analysis.
Krendel M, Leh S, Garone ME, Edwards-Richards A, Lin JJ, Brackman D, Knappskog P, Mikhailov A., Free PMC Article | 12/24/2022 |
| Steroid-Resistant Nephrotic Syndrome-Associated MYO1E Mutations Have Differential Effects on Myosin 1e Localization, Dynamics, and Activity. | Steroid-Resistant Nephrotic Syndrome-Associated MYO1E Mutations Have Differential Effects on Myosin 1e Localization, Dynamics, and Activity.
Liu PJ, Gunther LK, Garone ME, Zhang C, Perez D, Bi-Karchin J, Pellenz CD, Chase SE, Presti MF, Plante EL, Martin CE, Lovric S, Yengo CM, Hildebrandt F, Krendel M., Free PMC Article | 11/5/2022 |
| TH12 domain of Myo1e serves as a regulatory component to connect phosphatidylinositol signaling to F-actin polymerization at the podosome. | Tail domains of myosin-1e regulate phosphatidylinositol signaling and F-actin polymerization at the ventral layer of podosomes.
Zhang Y, Cao F, Zhou Y, Feng Z, Sit B, Krendel M, Yu CH., Free PMC Article | 06/29/2019 |
| our data suggests that MYO1E contributes to breast tumor malignancy and regulates the differentiation and proliferation state of breast tumor cells. | Myosin 1e promotes breast cancer malignancy by enhancing tumor cell proliferation and stimulating tumor cell de-differentiation.
Ouderkirk-Pecone JL, Goreczny GJ, Chase SE, Tatum AH, Turner CE, Krendel M., Free PMC Article | 02/3/2018 |
| The ERK signaling pathway thus promotes cell motility through regulation of the subcellular localization of Myo1E. | ERK signaling promotes cell motility by inducing the localization of myosin 1E to lamellipodial tips.
Tanimura S, Hashizume J, Arichika N, Watanabe K, Ohyama K, Takeda K, Kohno M., Free PMC Article | 06/3/2017 |
| Coinheritance of COL4A5 and MYO1E mutations accentuate the severity of kidney disease. | Coinheritance of COL4A5 and MYO1E mutations accentuate the severity of kidney disease.
Lennon R, Stuart HM, Bierzynska A, Randles MJ, Kerr B, Hillman KA, Batra G, Campbell J, Storey H, Flinter FA, Koziell A, Welsh GI, Saleem MA, Webb NJ, Woolf AS., Free PMC Article | 08/6/2016 |
| Myo1e is a key component contributing to the functional integrity of podocytes. | Myo1e impairment results in actin reorganization, podocyte dysfunction, and proteinuria in zebrafish and cultured podocytes.
Mao J, Wang D, Mataleena P, He B, Niu D, Katayama K, Xu X, Ojala JR, Wang W, Shu Q, Du L, Liu A, Pikkarainen T, Patrakka J, Tryggvason K., Free PMC Article | 01/24/2015 |
| MYO1E mutations are not a major cause of Chinese familial Steroid-resistant nephrotic syndrome. | [Mutational analysis of MYO1E in Chinese children with familial steroid-resistant nephrotic syndrome].
Zhao F, Yu ZH, Yang YH, Nie XJ, Huang J, Wang CF, Xia GZ, Chen GM. | 08/30/2014 |
| Homozygosity mapping and exome sequencing in a consanguineous kindred identified MYO1E and NEIL1 as novel candidate genes for human autosomal recessive steroid-resistant nephrotic syndrome. | Exome sequencing identified MYO1E and NEIL1 as candidate genes for human autosomal recessive steroid-resistant nephrotic syndrome.
Sanna-Cherchi S, Burgess KE, Nees SN, Caridi G, Weng PL, Dagnino M, Bodria M, Carrea A, Allegretta MA, Kim HR, Perry BJ, Gigante M, Clark LN, Kisselev S, Cusi D, Gesualdo L, Allegri L, Scolari F, D'Agati V, Shapiro LS, Pecoraro C, Palomero T, Ghiggeri GM, Gharavi AG. | 12/10/2011 |
| MYO1E mutations are associated with childhood-onset, glucocorticoid-resistant focal segmental glomerulosclerosis. | MYO1E mutations and childhood familial focal segmental glomerulosclerosis.
Mele C, Iatropoulos P, Donadelli R, Calabria A, Maranta R, Cassis P, Buelli S, Tomasoni S, Piras R, Krendel M, Bettoni S, Morigi M, Delledonne M, Pecoraro C, Abbate I, Capobianchi MR, Hildebrandt F, Otto E, Schaefer F, Macciardi F, Ozaltin F, Emre S, Ibsirlioglu T, Benigni A, Remuzzi G, Noris M, PodoNet Consortium., Free PMC Article | 08/6/2011 |
| myo1e binds lipids through nonspecific electrostatic interactions rather than a stereospecific protein-phosphoinositide interaction. | Myo1e binds anionic phospholipids with high affinity.
Feeser EA, Ignacio CM, Krendel M, Ostap EM., Free PMC Article | 12/4/2010 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| The kinetic mechanism of Myo1e (human myosin-IC). | The kinetic mechanism of Myo1e (human myosin-IC).
El Mezgueldi M, Tang N, Rosenfeld SS, Ostap EM. | 01/21/2010 |
| Two proteins with prominent functions in endocytosis, synaptojanin-1 and dynamin, bind to the SH3 domain of human Myo1E. | Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis.
Krendel M, Osterweil EK, Mooseker MS., Free PMC Article | 01/21/2010 |