| TRIM37 interacts with EZH2 to epigenetically suppress PTCH1 and regulate stemness in glioma stem cells through sonic hedgehog pathway. | TRIM37 interacts with EZH2 to epigenetically suppress PTCH1 and regulate stemness in glioma stem cells through sonic hedgehog pathway.
Cai L, Liu Y, Li Y, Liu B, Cao Y, Yang W, Wang B, Sun T. | 08/23/2024 |
| TRIM37 promotes the aggressiveness of ovarian cancer cells and increases c-Myc expression by binding to HUWE1. | TRIM37 promotes the aggressiveness of ovarian cancer cells and increases c-Myc expression by binding to HUWE1.
Li D, Zhang Z. | 09/10/2022 |
| TRIM37 Augments AP-2gamma Transcriptional Activity and Cellular Localization via K63-linked Ubiquitination to Drive Breast Cancer Progression. | TRIM37 Augments AP-2γ Transcriptional Activity and Cellular Localization via K63-linked Ubiquitination to Drive Breast Cancer Progression.
Cui G, Gao Z, Chang S, Narwade N, Chen Y, Poudel B, Lei KMK, Zhang W, Li G, Poon TCW, Cheung E., Free PMC Article | 07/30/2022 |
| Liver pathology and biochemistry in patients with mutations in TRIM37 gene (Mulibrey nanism). | Liver pathology and biochemistry in patients with mutations in TRIM37 gene (Mulibrey nanism).
Sivunen J, Karlberg S, Kivisaari R, Lohi J, Karlberg N, Jokinen E, Sarkola T, Jahnukainen T, Lipsanen-Nyman M, Jalanko H., Free PMC Article | 06/18/2022 |
| TRIM37 Promotes Pancreatic Cancer Progression through Modulation of Cell Growth, Migration, Invasion, and Tumor Immune Microenvironment. | TRIM37 Promotes Pancreatic Cancer Progression through Modulation of Cell Growth, Migration, Invasion, and Tumor Immune Microenvironment.
Do TT, Yeh CC, Wu GW, Hsu CC, Chang HC, Chen HC., Free PMC Article | 03/5/2022 |
| TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin. | TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin.
Balestra FR, Domínguez-Calvo A, Wolf B, Busso C, Buff A, Averink T, Lipsanen-Nyman M, Huertas P, Ríos RM, Gönczy P., Free PMC Article | 02/5/2022 |
| Circular RNA circRNA_101996 promoted cervical cancer development by regulating miR-1236-3p/TRIM37 axis. | Circular RNA circRNA_101996 promoted cervical cancer development by regulating miR-1236-3p/TRIM37 axis.
Song TF, Xu AL, Chen XH, Gao JY, Gao F, Kong XC. | 01/8/2022 |
| TRIM37 orchestrates renal cell carcinoma progression via histone H2A ubiquitination-dependent manner. | TRIM37 orchestrates renal cell carcinoma progression via histone H2A ubiquitination-dependent manner.
Miao C, Liang C, Li P, Liu B, Qin C, Yuan H, Liu Y, Zhu J, Cui Y, Xu A, Wang S, Su S, Li J, Shao P, Wang Z., Free PMC Article | 01/1/2022 |
| ASB16-AS1 up-regulated and phosphorylated TRIM37 to activate NF-kappaB pathway and promote proliferation, stemness, and cisplatin resistance of gastric cancer. | ASB16-AS1 up-regulated and phosphorylated TRIM37 to activate NF-κB pathway and promote proliferation, stemness, and cisplatin resistance of gastric cancer.
Fu T, Ji K, Jin L, Zhang J, Wu X, Ji X, Fan B, Jia Z, Wang A, Liu J, Bu Z, Ji J. | 11/13/2021 |
| TRIM37 prevents formation of condensate-organized ectopic spindle poles to ensure mitotic fidelity. | TRIM37 prevents formation of condensate-organized ectopic spindle poles to ensure mitotic fidelity.
Meitinger F, Kong D, Ohta M, Desai A, Oegema K, Loncarek J., Free PMC Article | 10/9/2021 |
| TRIM37 negatively regulates inflammatory responses induced by virus infection via controlling TRAF6 ubiquitination. | TRIM37 negatively regulates inflammatory responses induced by virus infection via controlling TRAF6 ubiquitination.
Zhao L, Hao Y, Song Z, Fan Y, Li S. | 07/24/2021 |
| TRIM37 is highly expressed during mitosis in CHON-002 chondrocytes cell line and is regulated by miR-223. | TRIM37 is highly expressed during mitosis in CHON-002 chondrocytes cell line and is regulated by miR-223.
Brigant B, Demont Y, Ouled-Haddou H, Metzinger-Le Meuth V, Testelin S, Garçon L, Metzinger L, Rochette J. | 06/26/2021 |
| Ginkgolide B protects human pulmonary alveolar epithelial A549 cells from lipopolysaccharide-induced inflammatory responses by reducing TRIM37-mediated NF-kappaB activation. | Ginkgolide B protects human pulmonary alveolar epithelial A549 cells from lipopolysaccharide-induced inflammatory responses by reducing TRIM37-mediated NF-κB activation.
Xiang Y, Zhang S, Lu J, Zhang W, Cai M, Xiang J, Cai D. | 06/5/2021 |
| Oncogenic TRIM37 Links Chemoresistance and Metastatic Fate in Triple-Negative Breast Cancer. | Oncogenic TRIM37 Links Chemoresistance and Metastatic Fate in Triple-Negative Breast Cancer.
Przanowski P, Lou S, Tihagam RD, Mondal T, Conlan C, Shivange G, Saltani I, Singh C, Xing K, Morris BB, Mayo MW, Teixeira L, Lehmann-Che J, Tushir-Singh J, Bhatnagar S., Free PMC Article | 02/6/2021 |
| TRIM37 controls cancer-specific vulnerability to PLK4 inhibition. | TRIM37 controls cancer-specific vulnerability to PLK4 inhibition.
Meitinger F, Ohta M, Lee KY, Watanabe S, Davis RL, Anzola JV, Kabeche R, Jenkins DA, Shiau AK, Desai A, Oegema K., Free PMC Article | 12/12/2020 |
| Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer. | Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.
Yeow ZY, Lambrus BG, Marlow R, Zhan KH, Durin MA, Evans LT, Scott PM, Phan T, Park E, Ruiz LA, Moralli D, Knight EG, Badder LM, Novo D, Haider S, Green CM, Tutt ANJ, Lord CJ, Chapman JR, Holland AJ., Free PMC Article | 12/5/2020 |
| TRIM37 has a role in apoptosis and IL-1beta release in mouse BV-2 microglia that involves PPARgamma ubiquitination; it is increased in mononuclear leukocytes of intracerebral hemorrhage patients | Tripartite motif containing protein 37 involves in thrombin stimulated BV-2 microglial cell apoptosis and interleukin 1β release.
Han C, Xia X, Jiao S, Li G, Ran Q, Yao S. | 06/13/2020 |
| TRIM37 bound to TRAF2 and induced K63-linked ubiquitination of TRAF2, sustaining the eventual activation of the NF-kappaB pathway, promoting the aggressiveness of non-small-cell lung cancer cells. | Tripartite motif-containing 37 (TRIM37) promotes the aggressiveness of non-small-cell lung cancer cells by activating the NF-κB pathway.
Li Y, Deng L, Zhao X, Li B, Ren D, Yu L, Pan H, Gong Q, Song L, Zhou X, Dai T. | 10/26/2019 |
| This study unveils a positive role of TRIM37 in regulating the MTORC1-TFEB axis. | TRIM37 deficiency induces autophagy through deregulating the MTORC1-TFEB axis.
Wang W, Xia Z, Farré JC, Subramani S., Free PMC Article | 10/19/2019 |
| Genotoxic stress-activates ATM kinase directly interacted with and phosphorylated TRIM37 in the cytoplasm, which induced translocation of TRIM37 into the nucleus, where it formed a complex with NEMO and TRAF6 via a TRAF6-binding motif (TBM) | An ATM/TRIM37/NEMO Axis Counteracts Genotoxicity by Activating Nuclear-to-Cytoplasmic NF-κB Signaling.
Wu G, Song L, Zhu J, Hu Y, Cao L, Tan Z, Zhang S, Li Z, Li J. | 10/12/2019 |
| TRIM37 functions as an oncogene in the development and progression of glioma. | Knockdown of TRIM37 suppresses the proliferation, migration and invasion of glioma cells through the inactivation of PI3K/Akt signaling pathway.
Tang SL, Gao YL, Wen-Zhong H. | 08/25/2018 |
| TRIM37 mutation is associated with mulibrey nanism. | New intragenic rearrangements in non-Finnish mulibrey nanism.
Jobic F, Morin G, Vincent-Delorme C, Cadet E, Cabry R, Mathieu-Dramard M, Copin H, Rochette J, Jedraszak G. | 02/10/2018 |
| TRIM37-mediated ubiquitylation stabilizes PEX5 and promotes peroxisomal matrix protein import, suggesting that mulibrey nanism is a new peroxisomal biogenesis disorder. | TRIM37, a novel E3 ligase for PEX5-mediated peroxisomal matrix protein import.
Wang W, Xia ZJ, Farré JC, Subramani S., Free PMC Article | 10/7/2017 |
| TRIM37 was overexpressed in human CRC tissues. High TRIM37 expression resulted in increased CRC proliferation, migration and invasion. Mechanistically, it was confirmed that TRIM37 enhanced invasion and metastasis of CRC via the epithelialmesenchymal transition pathway. | TRIM37 promotes epithelial‑mesenchymal transition in colorectal cancer.
Hu CE, Gan J., Free PMC Article | 05/13/2017 |
| knockdown of TRIM37 markedly downregulated the expression of beta-catenin, cyclin D1, and c-Myc in CRC cells. These results suggest that knockdown of TRIM37 inhibits proliferation and tumorigenesis by the inactivation of Wnt/beta-catenin signaling in CRC cells. | Knockdown of Tripartite Motif-Containing Protein 37 (TRIM37) Inhibits the Proliferation and Tumorigenesis in Colorectal Cancer Cells.
Zhao P, Guan HT, Dai ZJ, Ma YG, Liu XX, Wang XJ., Free PMC Article | 03/18/2017 |