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    MUC5AC mucin 5AC, oligomeric mucus/gel-forming [ Homo sapiens (human) ]

    Gene ID: 4586, updated on 12-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    MUC5AC Genetic Variation Is Associated With Tuberculous Meningitis Cerebral Spinal Fluid Cytokine Responses and Mortality.

    MUC5AC Genetic Variation Is Associated With Tuberculous Meningitis Cerebral Spinal Fluid Cytokine Responses and Mortality.
    Sabo MC, Thuong NTT, Chang X, Ardiansyah E, Tram TTB, Hai HT, Nghia HDT, Bang ND, Dian S, Ganiem AR, Shaporifar S, Kumar V, Li Z, Hibberd M, Khor CC, Thwaites GE, Heemskerk D, van Laarhoven A, van Crevel R, Dunstan SJ, Shah JA., Free PMC Article

    08/17/2023
    Predictive Value of MUC5AC Signature in Pancreatic Ductal Adenocarcinoma: A Hypothesis Based on Preclinical Evidence.

    Predictive Value of MUC5AC Signature in Pancreatic Ductal Adenocarcinoma: A Hypothesis Based on Preclinical Evidence.
    Manne A, Kasi A, Esnakula AK, Paluri RK., Free PMC Article

    06/7/2023
    The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.

    The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.
    Khorasani AM, Mohammadi B, Saghafi MR, Mohammadi S, Ghaffari S, Mirsadraee M, Khakzad MR.

    05/23/2023
    Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.

    Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.
    Baumlin N, Silswal N, Dennis JS, Niloy AJ, Kim MD, Salathe M., Free PMC Article

    02/4/2023
    Evaluation of MUC1, MUC2, MUC5AC, and MUC6 Expression Differences in Lung Adenocarcinoma Subtypes by Using a Final Immunoreactivity Score (FIRS).

    Evaluation of MUC1, MUC2, MUC5AC, and MUC6 Expression Differences in Lung Adenocarcinoma Subtypes by Using a Final Immunoreactivity Score (FIRS).
    Buyuk M, Ozluk Y, Bakkaloglu DV, Ozkan B, Firat P, Yilmazbayhan D., Free PMC Article

    01/21/2023
    MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.

    MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.
    Song D, Iverson E, Kaler L, Boboltz A, Scull MA, Duncan GA., Free PMC Article

    12/24/2022
    The Regulation Mechanism of MUC5AC Secretion in Airway of Obese Asthma.

    The Regulation Mechanism of MUC5AC Secretion in Airway of Obese Asthma.
    Li T, Wang Y, Huang S, Tang H.

    12/17/2022
    De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.

    De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.
    Vial Y, Lainey E, Leblanc T, Baudouin V, Dourthe ME, Gressens P, Verloes A, Cavé H, Drunat S.

    12/3/2022
    Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.

    Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.
    Hoang ON, Ermund A, Jaramillo AM, Fakih D, French CB, Flores JR, Karmouty-Quintana H, Magnusson JM, Fois G, Fauler M, Frick M, Braubach P, Hales JB, Kurten RC, Panettieri R, Vergara L, Ehre C, Adachi R, Tuvim MJ, Hansson GC, Dickey BF., Free PMC Article

    11/5/2022
    HNE Induces the Hyperexpression of MUC5AC in Chronic Rhinosinusitis With Nasal Polyps by Activating the TRAF6/Autophagy Regulatory Axis.

    HNE Induces the Hyperexpression of MUC5AC in Chronic Rhinosinusitis With Nasal Polyps by Activating the TRAF6/Autophagy Regulatory Axis.
    Zhang Y, Qi J, Yan D, Deng Y, Zhang J, Luo Q.

    10/15/2022
    Serum MUC5AC protein levels are correlated with the development and severity of connective tissue disease-associated pulmonary interstitial lesions.

    Serum MUC5AC protein levels are correlated with the development and severity of connective tissue disease-associated pulmonary interstitial lesions.
    Weng L, Liu W, Wang L, Wu Z, Liu D, Lin Y, Song S, Yu C, Chen Y, Chen J, Ge S., Free PMC Article

    10/8/2022
    Autocrine TGF-alpha is associated with Benzo(a)pyrene-induced mucus production and MUC5AC expression during allergic asthma.

    Autocrine TGF-alpha is associated with Benzo(a)pyrene-induced mucus production and MUC5AC expression during allergic asthma.
    Sun Y, Miao X, Zhu L, Liu J, Lin Y, Xiang G, Wu X, Wang X, Ni Z, Li S.

    09/17/2022
    Home Dust Mites Promote MUC5AC Hyper-Expression by Modulating the sNASP/TRAF6 Axis in the Airway Epithelium.

    Home Dust Mites Promote MUC5AC Hyper-Expression by Modulating the sNASP/TRAF6 Axis in the Airway Epithelium.
    Chen MZ, Wang SA, Hsu SC, Silva KAS, Yang FM., Free PMC Article

    09/3/2022
    Mucin 5AC-Mediated CD44/ITGB1 Clustering Mobilizes Adipose-Derived Mesenchymal Stem Cells to Modulate Pancreatic Cancer Stromal Heterogeneity.

    Mucin 5AC-Mediated CD44/ITGB1 Clustering Mobilizes Adipose-Derived Mesenchymal Stem Cells to Modulate Pancreatic Cancer Stromal Heterogeneity.
    Ganguly K, Cox JL, Ghersi D, Grandgenett PM, Hollingsworth MA, Jain M, Kumar S, Batra SK., Free PMC Article

    05/21/2022
    A combination of immunohistochemical markers, MUC1, MUC5AC, PAX8 and growth pattern for characterization of mucinous neoplasm of the ovary.

    A combination of immunohistochemical markers, MUC1, MUC5AC, PAX8 and growth pattern for characterization of mucinous neoplasm of the ovary.
    Chelariu-Raicu A, Holley E, Mayr D, Klauschen F, Wehweck F, Rottmann M, Kessler M, Kaltofen T, Czogalla B, Trillsch F, Mahner S, Schmoeckel E.

    05/14/2022
    Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.

    Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.
    Tajiri T, Matsumoto H, Jinnai M, Kanemitsu Y, Nagasaki T, Iwata T, Inoue H, Nakaji H, Oguma T, Ito I, Niimi A.

    04/9/2022
    Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.

    Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.
    Radicioni G, Ceppe A, Ford AA, Alexis NE, Barr RG, Bleecker ER, Christenson SA, Cooper CB, Han MK, Hansel NN, Hastie AT, Hoffman EA, Kanner RE, Martinez FJ, Ozkan E, Paine R 3rd, Woodruff PG, O'Neal WK, Boucher RC, Kesimer M., Free PMC Article

    03/26/2022
    Analysis of blood group antigens on MUC5AC in mucinous ovarian cancer tissues using in situ proximity ligation assay.

    Analysis of blood group antigens on MUC5AC in mucinous ovarian cancer tissues using in situ proximity ligation assay.
    Mateoiu C, Vitiazeva V, Kristjansdottir B, Weijdegård B, Örnros J, Gallini R, Kamali-Moghaddam M, Sundfeldt K, Karlsson NG., Free PMC Article

    03/19/2022
    The protective effects of Omarigliptin against Lipopolysaccharide (LPS)- induced inflammatory response and expression of mucin 5AC (MUC5AC) in human bronchial epithelial cells.

    The protective effects of Omarigliptin against Lipopolysaccharide (LPS)- induced inflammatory response and expression of mucin 5AC (MUC5AC) in human bronchial epithelial cells.
    Ma L, Chang E, Ruan X, Zhang B, Tang F, Zhang J.

    02/26/2022
    Epithelial Aryl Hydrocarbon Receptor Protects From Mucus Production by Inhibiting ROS-Triggered NLRP3 Inflammasome in Asthma.

    Epithelial Aryl Hydrocarbon Receptor Protects From Mucus Production by Inhibiting ROS-Triggered NLRP3 Inflammasome in Asthma.
    Hu X, Shen Y, Zhao Y, Wang J, Zhang X, Tu W, Kaufman W, Feng J, Gao P., Free PMC Article

    02/19/2022
    MUC5AC expression is linked to mucinous/endometroid subtype, absence of nodal metastasis and mismatch repair deficiency in ovarian cancer.

    MUC5AC expression is linked to mucinous/endometroid subtype, absence of nodal metastasis and mismatch repair deficiency in ovarian cancer.
    Rico SD, Schmalfeldt B, Müller V, Wölber L, Witzel I, Paluchowski P, von Leffern I, Heilenkötter U, Jacobsen F, Bernreuther C, Clauditz T, Simon R, Steurer S, Burandt E, Marx AH, Krech T.

    01/22/2022
    Mucin 5AC Serves as the Nexus for beta-Catenin/c-Myc Interplay to Promote Glutamine Dependency During Pancreatic Cancer Chemoresistance.

    Mucin 5AC Serves as the Nexus for β-Catenin/c-Myc Interplay to Promote Glutamine Dependency During Pancreatic Cancer Chemoresistance.
    Ganguly K, Bhatia R, Rauth S, Kisling A, Atri P, Thompson C, Vengoji R, Ram Krishn S, Shinde D, Thomas V, Kaur S, Mallya K, Cox JL, Kumar S, Batra SK., Free PMC Article

    01/22/2022
    Establishment of Patient-derived Preclinical Models for Invasive Papillary Cholangiocarcinoma.

    Establishment of Patient-derived Preclinical Models for Invasive Papillary Cholangiocarcinoma.
    Mwesige B, Lee MR, Lee YS, Han NY, Im JE, Kim JK, Choi SI, Hong EK, Jeon AR, Park SJ, Woo SM, Kim YH.

    01/15/2022
    Quantification of increased MUC5AC expression in airway mucus of smoker using an automated image-based approach.

    Quantification of increased MUC5AC expression in airway mucus of smoker using an automated image-based approach.
    Groiss S, Somvilla I, Daxböck C, Fuchs J, Lang-Olip I, Stiegler P, Leber B, Liegl-Atzwanger B, Brislinger D.

    01/1/2022
    Inducible expression quantitative trait locus analysis of the MUC5AC gene in asthma in urban populations of children.

    Inducible expression quantitative trait locus analysis of the MUC5AC gene in asthma in urban populations of children.
    Altman MC, Flynn K, Rosasco MG, Dapas M, Kattan M, Lovinsky-Desir S, O'Connor GT, Gill MA, Gruchalla RS, Liu AH, Pongracic JA, Khurana Hershey GK, Zoratti EM, Teach SJ, Rastrogi D, Wood RA, Bacharier LB, LeBeau P, Gergen PJ, Togias A, Busse WW, Presnell S, Gern JE, Ober C, Jackson DJ, NIAID Inner City Asthma Consortium., Free PMC Article

    12/25/2021
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