| ENY2 Protein Interacts with RNA Helicase MLE | Multifunctional ENY2 Protein Interacts with RNA Helicase MLE.
Nikolenko JV, Kurshakova MM, Krasnov AN. | 05/16/2020 |
| Evolutionarily conserved ENY2 is responsible for barrier activity mediated by the dCTCF protein. | Highly conserved ENY2/Sus1 protein binds to Drosophila CTCF and is required for barrier activity.
Maksimenko O, Kyrchanova O, Bonchuk A, Stakhov V, Parshikov A, Georgiev P., Free PMC Article | 05/16/2015 |
| The transcription coactivators SAYP and ENY2 act in gene expression as cooperative nanoregulators,determining the molecular mechanisms of spatial and temporal coordination of the processes involved in the realization of genetic information. | [Functioning of macromolecular complexes at successive stages of gene expression as self-coordinated molecular machines].
Brechalov AV, Gurskiĭ DIa, Georgieva SG, Shidlovskiĭ IuV. | 12/24/2011 |
| ENY2 protein forms a part of the THO complex of Drosophila melanogaster. | ENY2 protein forms a part of the THO complex of Drosophila melanogaster.
Gurskiy DY, Nabirochkina EN, Kopytova DV, Nikolenko YV, Ilyin YV, Georgieva SG, Shidlovskii YV. | 12/4/2010 |
| 368-bp core of E(y)2 insulator is sufficient for blocking Polycomb response element-mediated silencing. | E(y)2/Sus1 is required for blocking PRE silencing by the Wari insulator in Drosophila melanogaster.
Erokhin M, Parshikov A, Georgiev P, Chetverina D. | 08/23/2010 |
| ENY2 in Drosophila is also stably associated with THO, the complex involved in mRNP biogenesis | Multifunctional factor ENY2 is associated with the THO complex and promotes its recruitment onto nascent mRNA.
Kopytova DV, Orlova AV, Krasnov AN, Gurskiy DY, Nikolenko JV, Nabirochkina EN, Shidlovskii YV, Georgieva SG., Free PMC Article | 01/21/2010 |
| E(y)2 and Xmas-2 together with SAGA/TFTC functioned in the anchoring of a subset of transcription sites to the NPCs to achieve efficient transcription and mRNA export. | [Conservative E(y)2/Sus1 protein is the member of SAGA complex and new nuclear pore-associated complex in Drosophila].
Kurshakova MM, Kopytova DV, Nabirochkina EN, Nikolenko IuV, Shidlovskiĭ IuV, Georgieva SG, Krasnov AN. | 01/21/2010 |
| E(y)2, the novel component of SAGA/TFTC complex in eucaryotes participates in export of mRNP from nucleus and couples transcription with nuclear pore | [E(y)2, the novel component of SAGA/TFTC complex in eucaryotes participates in export of mRNP from nucleus and couples transcription with nuclear pore].
Kurshakova MM, Nabirochkina EN, Georgieva SG. | 01/21/2010 |
| transcription factor E(y)2/Sus1 interacted with the Su(Hw) zinc-finger domain and was present in the protein complex, associated with the Su(Hw)-dependent insulators. | [Conservative E(y)2/Sus1 protein interacts with the Su(Hw)-dependent insulators in Drosophila].
Kurshakova MM, Kopytova DV, Nabirochkina EN, Soshnikova NV, Georgieva SG, Krasnov AN. | 01/21/2010 |
| 3 additional subunits of TFTC/STAGA (ATXN7L3, USP22, & ENY2) help form the deubiquitination module. This module is an enhancer of position effect variegation in Drosophila. ATXN7L3 and USP22. | A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.
Zhao Y, Lang G, Ito S, Bonnet J, Metzger E, Sawatsubashi S, Suzuki E, Le Guezennec X, Stunnenberg HG, Krasnov A, Georgieva SG, Schüle R, Takeyama K, Kato S, Tora L, Devys D. | 01/21/2010 |
| The e(y)2 gene derived as a result of retroposition of the e(y)2b gene during Drosophila evolution. | A retrocopy of a gene can functionally displace the source gene in evolution.
Krasnov AN, Kurshakova MM, Ramensky VE, Mardanov PV, Nabirochkina EN, Georgieva SG, Krasnov AN, Kurshakova MM, Ramensky VE, Mardanov PV, Nabirochkina EN, Georgieva SG., Free PMC Articles: PMC1298928, PMC1298928 | 01/21/2010 |
| The e(y)2b gene is a paralogue of the e(y)2 gene. | A retrocopy of a gene can functionally displace the source gene in evolution.
Krasnov AN, Kurshakova MM, Ramensky VE, Mardanov PV, Nabirochkina EN, Georgieva SG, Krasnov AN, Kurshakova MM, Ramensky VE, Mardanov PV, Nabirochkina EN, Georgieva SG., Free PMC Articles: PMC1298928, PMC1298928 | 01/21/2010 |