| The structure of the second CysD domain of MUC2 and role in mucin organization by transglutaminase-based cross-linking. | The structure of the second CysD domain of MUC2 and role in mucin organization by transglutaminase-based cross-linking.
Recktenwald CV, Karlsson G, Garcia-Bonete MJ, Katona G, Jensen M, Lymer R, Bäckström M, Johansson MEV, Hansson GC, Trillo-Muyo S. | 09/24/2024 |
| REGgamma Mitigates Radiation-Induced Enteritis by Preserving Mucin Secretion and Sustaining Microbiome Homeostasis. | REGγ Mitigates Radiation-Induced Enteritis by Preserving Mucin Secretion and Sustaining Microbiome Homeostasis.
Zhu X, Li Y, Tian X, Jing Y, Wang Z, Yue L, Li J, Wu L, Zhou X, Yu Z, Zhang Y, Guan F, Yang M, Zhang B. | 08/7/2024 |
| POFUT1 and PLAGL2 are characteristic markers of mucinous colorectal cancer associated with MUC2 expression. | POFUT1 and PLAGL2 are characteristic markers of mucinous colorectal cancer associated with MUC2 expression.
Monno M, Ogiri M, Seishima R, Suzuki Y, Hattori K, Matsui S, Shigeta K, Okabayashi K, Kitagawa Y. | 03/20/2024 |
| An Increase in Mucin2 Expression Is Required for Colon Cancer Progression Mediated by L1. | An Increase in Mucin2 Expression Is Required for Colon Cancer Progression Mediated by L1.
Saha A, Gavert N, Brabletz T, Ben-Ze'ev A., Free PMC Article | 09/19/2023 |
| Evaluation of MUC1, MUC2, MUC5AC, and MUC6 Expression Differences in Lung Adenocarcinoma Subtypes by Using a Final Immunoreactivity Score (FIRS). | Evaluation of MUC1, MUC2, MUC5AC, and MUC6 Expression Differences in Lung Adenocarcinoma Subtypes by Using a Final Immunoreactivity Score (FIRS).
Buyuk M, Ozluk Y, Bakkaloglu DV, Ozkan B, Firat P, Yilmazbayhan D., Free PMC Article | 01/21/2023 |
| Endotoxins Induced ECM-Receptor Interaction Pathway Signal Effect on the Function of MUC2 in Caco2/HT29 Co-Culture Cells. | Endotoxins Induced ECM-Receptor Interaction Pathway Signal Effect on the Function of MUC2 in Caco2/HT29 Co-Culture Cells.
Hu W, Feng P, Zhang M, Tian T, Wang S, Zhao B, Li Y, Wang S, Wu C., Free PMC Article | 07/2/2022 |
| Next-generation sequencing analysis suggests varied multistep mutational pathogenesis for endocrine mucin-producing sweat gland carcinoma with comments on INSM1 and MUC2 suggesting a conjunctival origin. | Next-generation sequencing analysis suggests varied multistep mutational pathogenesis for endocrine mucin-producing sweat gland carcinoma with comments on INSM1 and MUC2 suggesting a conjunctival origin.
Mathew JG, Bowman AS, Saab J, Busam KJ, Nehal K, Pulitzer M., Free PMC Article | 05/14/2022 |
| Enterotoxigenic Escherichia coli Degrades the Host MUC2 Mucin Barrier To Facilitate Critical Pathogen-Enterocyte Interactions in Human Small Intestine. | Enterotoxigenic Escherichia coli Degrades the Host MUC2 Mucin Barrier To Facilitate Critical Pathogen-Enterocyte Interactions in Human Small Intestine.
Sheikh A, Wangdi T, Vickers TJ, Aaron B, Palmer M, Miller MJ, Kim S, Herring C, Simoes R, Crainic JA, Gildersleeve JC, van der Post S, Hansson GC, Fleckenstein JM., Free PMC Article | 04/23/2022 |
| Utility of Insulinoma-Associated Protein 1 (INSM1) and Mucin 2 (MUC2) Immunohistochemistry in the Distinction of Endocrine Mucin-Producing Sweat Gland Carcinoma From Morphologic Mimics. | Utility of Insulinoma-Associated Protein 1 (INSM1) and Mucin 2 (MUC2) Immunohistochemistry in the Distinction of Endocrine Mucin-Producing Sweat Gland Carcinoma From Morphologic Mimics.
Quattrochi B, Russell-Goldman E. | 03/26/2022 |
| MUC2 and related bacterial factors: Therapeutic targets for ulcerative colitis. | MUC2 and related bacterial factors: Therapeutic targets for ulcerative colitis.
Yao D, Dai W, Dong M, Dai C, Wu S., Free PMC Article | 03/26/2022 |
| Rare minisatellite alleles of MUC2-MS8 influence susceptibility to rectal carcinoma. | Rare minisatellite alleles of MUC2-MS8 influence susceptibility to rectal carcinoma.
Seol SY, Yang GE, Cho Y, Kim MC, Choi HJ, Choi YH, Leem SH. | 03/19/2022 |
| Prognostic role of MUC-2 expression in patients with gastric carcinoma: a systematic review and meta-analysis. | Prognostic role of MUC-2 expression in patients with gastric carcinoma: a systematic review and meta-analysis.
Hu LN, Su W, Guo XZ, Xu T, Wang H, Yu MH. | 02/26/2022 |
| Autophagy is required during high MUC2 mucin biosynthesis in colonic goblet cells to contend metabolic stress. | Autophagy is required during high MUC2 mucin biosynthesis in colonic goblet cells to contend metabolic stress.
Tiwari S, Begum S, Moreau F, Gorman H, Chadee K. | 11/13/2021 |
| DOCK4 stimulates MUC2 production through its effect on goblet cell differentiation. | DOCK4 stimulates MUC2 production through its effect on goblet cell differentiation.
Qin T, Yang J, Huang D, Zhang Z, Huang Y, Chen H, Xu G. | 11/13/2021 |
| Associations between the expression of mucins (MUC1, MUC2, MUC5AC and MUC6) and clinicopathologic parameters of human breast carcinomas. | Associations between the expression of mucins (MUC1, MUC2, MUC5AC and MUC6) and clinicopathologic parameters of human breast carcinomas.
Oral O, Unverdi H, Kumcu E, Turkbey D, Dogan S, Hucumenoglu S. | 07/24/2021 |
| Assembly Mechanism of Mucin and von Willebrand Factor Polymers. | Assembly Mechanism of Mucin and von Willebrand Factor Polymers.
Javitt G, Khmelnitsky L, Albert L, Bigman LS, Elad N, Morgenstern D, Ilani T, Levy Y, Diskin R, Fass D., Free PMC Article | 05/22/2021 |
| Exogenous NAD(+) Stimulates MUC2 Expression in LS 174T Goblet Cells via the PLC-Delta/PTGES/PKC-Delta/ERK/CREB Signaling Pathway. | Exogenous NAD(+) Stimulates MUC2 Expression in LS 174T Goblet Cells via the PLC-Delta/PTGES/PKC-Delta/ERK/CREB Signaling Pathway.
Ma S, Yeom J, Lim YH., Free PMC Article | 04/13/2021 |
| The role of MUC2 mucin in intestinal homeostasis and the impact of dietary components on MUC2 expression. | The role of MUC2 mucin in intestinal homeostasis and the impact of dietary components on MUC2 expression.
Liu Y, Yu X, Zhao J, Zhang H, Zhai Q, Chen W. | 04/3/2021 |
| Mucin Expression in Colorectal Cancer (CRC): Systematic Review and Meta-Analysis. | Mucin Expression in Colorectal Cancer (CRC): Systematic Review and Meta-Analysis.
Niv Y, Rokkas T. | 09/12/2020 |
| Somatostatin could participate in colonic mucus barrier regulation through SSTR5-Notch-Hes1-MUC2 signaling pathway. | Somatostatin stimulates colonic MUC2 expression through SSTR5-Notch-Hes1 signaling pathway.
Song S, Li X, Geng C, Li Y, Wang C. | 08/1/2020 |
| Specific conformation of glycosylated consecutive threonine motifs (TTX) motifs in MUC2 neoepitopes tandem repeats (TRs) is rationally rearranged by concerted motions of multiple dihedral angles and noncovalent interactions between the carbohydrate and peptide region. Autoantibody levels in sera of the late stage colorectal cancer (CRC) patients were distinctly lower than those of early stage CRC and normal individuals. | Impaired O-Glycosylation at Consecutive Threonine TTX Motifs in Mucins Generates Conformationally Restricted Cancer Neoepitopes.
Hayakawa S, Matsushita T, Yokoi Y, Wakui H, Garcia-Martin F, Hinou H, Matsuoka K, Nouso K, Kamiyama T, Taketomi A, Nishimura SI. | 07/11/2020 |
| our report identifies aberrant DNA methylation of MUC2 as a possible cause of extracellular production of mucin in mucinous breast cancer | Genomic, Transcriptomic, Epigenetic, and Immune Profiling of Mucinous Breast Cancer.
Nguyen B, Veys I, Leduc S, Bareche Y, Majjaj S, Brown DN, Boeckx B, Lambrechts D, Sotiriou C, Larsimont D, Desmedt C. | 07/11/2020 |
| The mucin 2 module structure thus reveals the manner by which both mucins and von Willebrand factor polymerize. | Intestinal Gel-Forming Mucins Polymerize by Disulfide-Mediated Dimerization of D3 Domains.
Javitt G, Calvo MLG, Albert L, Reznik N, Ilani T, Diskin R, Fass D., Free PMC Article | 06/20/2020 |
| SDR16C5 and SDR16C6 enzymes are not critical for survival but are responsible for most of the retinol dehydrogenase activity in skin, essential for the regulation of the hair-follicle cycle, and required for the maintenance of both sebaceous and meibomian glands | Calcium-activated chloride channel regulator 1 (CLCA1) forms non-covalent oligomers in colonic mucus and has mucin 2-processing properties.
Nyström EEL, Arike L, Ehrencrona E, Hansson GC, Johansson MEV., Free PMC Article | 06/13/2020 |
| hese results demonstrate that melatonin acting on MT2 inhibits the hypermethylation of the Muc2 promoter to restore the level of Muc2 production in intestinal epithelial cells infected with V. vulnificus. | Melatonin restores Muc2 depletion induced by V. vulnificus VvpM via melatonin receptor 2 coupling with Gαq.
Lee YM, Park JP, Jung YH, Lee HJ, Kim JS, Choi GE, Han HJ, Lee SJ., Free PMC Article | 06/6/2020 |