| Melatonin receptor 1A variants as genetic cause of idiopathic osteoporosis. | Melatonin receptor 1A variants as genetic cause of idiopathic osteoporosis.
Bisikirska B, Labella R, Cuesta-Dominguez A, Luo N, De Angelis J, Mosialou I, Lin CS, Beck D, Lata S, Shyu PT, McMahon DJ, Guo E, Hagen J, Chung WK, Shane E, Cohen A, Kousteni S. | 10/23/2024 |
| Rs4862705 in the melatonin receptor 1A gene is associated with renal function decline in type 1 diabetes individuals. | Rs4862705 in the melatonin receptor 1A gene is associated with renal function decline in type 1 diabetes individuals.
Daher G, Santos-Bezerra DP, Cavaleiro AM, Pelaes TS, Admoni SN, Perez RV, Machado CG, do Amaral FG, Cipolla-Neto J, Correa-Giannella ML., Free PMC Article | 04/3/2024 |
| Melatonin receptor 1A (MTNR1A) gene linkage and association to type 2 diabetes in Italian families. | Melatonin receptor 1A (MTNR1A) gene linkage and association to type 2 diabetes in Italian families.
Amin M, Gragnoli C. | 06/2/2023 |
| Association of rotating night shift work, CLOCK, MTNR1A, MTNR1B genes polymorphisms and their interactions with type 2 diabetes among steelworkers: a case-control study. | Association of rotating night shift work, CLOCK, MTNR1A, MTNR1B genes polymorphisms and their interactions with type 2 diabetes among steelworkers: a case-control study.
Li Q, Zhang S, Wang H, Wang Z, Zhang X, Wang Y, Yuan J., Free PMC Article | 05/9/2023 |
| MTNR1A and MTNR1B Gene Variants of the Melatonin Receptor and Arterial Stiffness in Persons without Arterial Hypertension. | MTNR1A and MTNR1B Gene Variants of the Melatonin Receptor and Arterial Stiffness in Persons without Arterial Hypertension.
Kolomeichuk SN, Korneva VA, Kuznetsova TY, Korostovtseva LS, Bochkarev MV, Sviryaev YV, Blagonravov ML. | 03/23/2023 |
| Association between genetic polymorphisms in the melatonin receptor type 1 A gene and sleep bruxism. | Association between genetic polymorphisms in the melatonin receptor type 1 A gene and sleep bruxism.
Gaio DC, Sebastiani AM, do Nascimento Meger M, Duarte J, Polmann H, Pauletto P, Réus JC, Souza JF, Souza AV, Machado-Souza C, Maia IS, Canto GL, Brancher JA. | 11/12/2022 |
| Melatonin Reverses the Warburg-Type Metabolism and Reduces Mitochondrial Membrane Potential of Ovarian Cancer Cells Independent of MT1 Receptor Activation. | Melatonin Reverses the Warburg-Type Metabolism and Reduces Mitochondrial Membrane Potential of Ovarian Cancer Cells Independent of MT1 Receptor Activation.
Cucielo MS, Cesário RC, Silveira HS, Gaiotte LB, Dos Santos SAA, de Campos Zuccari DAP, Seiva FRF, Reiter RJ, de Almeida Chuffa LG., Free PMC Article | 07/30/2022 |
| Structural basis of the ligand binding and signaling mechanism of melatonin receptors. | Structural basis of the ligand binding and signaling mechanism of melatonin receptors.
Wang Q, Lu Q, Guo Q, Teng M, Gong Q, Li X, Du Y, Liu Z, Tao Y., Free PMC Article | 02/19/2022 |
| MT1 and MT2 melatonin receptors play opposite roles in brain cancer progression. | MT1 and MT2 melatonin receptors play opposite roles in brain cancer progression.
Kinker GS, Ostrowski LH, Ribeiro PAC, Chanoch R, Muxel SM, Tirosh I, Spadoni G, Rivara S, Martins VR, Santos TG, Markus RP, Fernandes PACM. | 12/11/2021 |
| Melatonin 1A and 1B Receptors' Expression Decreases in the Placenta of Women with Fetal Growth Restriction. | Melatonin 1A and 1B Receptors' Expression Decreases in the Placenta of Women with Fetal Growth Restriction.
Berbets AM, Davydenko IS, Barbe AM, Konkov DH, Albota OM, Yuzko OM. | 11/27/2021 |
| The MTNR1A mRNA is stabilized by the cytoplasmic hnRNPL in renal tubular cells. | The MTNR1A mRNA is stabilized by the cytoplasmic hnRNPL in renal tubular cells.
Huang YS, Lu KC, Chao HW, Chen A, Chao TK, Guo CY, Hsieh HY, Shih HM, Sytwu HK, Wu CC. | 09/18/2021 |
| Nociceptive responses in melatonin MT2 receptor knockout mice compared to MT1 and double MT1 /MT2 receptor knockout mice. | Nociceptive responses in melatonin MT(2) receptor knockout mice compared to MT(1) and double MT(1) /MT(2) receptor knockout mice.
Posa L, Lopez-Canul M, Rullo L, De Gregorio D, Dominguez-Lopez S, Kaba Aboud M, Caputi FF, Candeletti S, Romualdi P, Gobbi G. | 07/31/2021 |
| Role of Melatonin in Breast Carcinoma: Correlation of Expression Patterns of Melatonin-1 Receptor With Estrogen, Progesterone, and HER2 Receptors. | Role of Melatonin in Breast Carcinoma: Correlation of Expression Patterns of Melatonin-1 Receptor With Estrogen, Progesterone, and HER2 Receptors.
Goyal R, Gupta T, Bal A, Sahni D, Singh G. | 07/31/2021 |
| Variation near MTNR1A associates with early development and interacts with seasons. | Variation near MTNR1A associates with early development and interacts with seasons.
Sulkava S, Taka AM, Kantojärvi K, Pölkki P, Morales-Muñoz I, Milani L, Porkka-Heiskanen T, Saarenpää-Heikkilä O, Kylliäinen A, Juulia Paavonen E, Paunio T. | 04/3/2021 |
| Expression of Melatonin and Dopamine D3 Receptor Heteromers in Eye Ciliary Body Epithelial Cells and Negative Correlation with Ocular Hypertension. | Expression of Melatonin and Dopamine D(3) Receptor Heteromers in Eye Ciliary Body Epithelial Cells and Negative Correlation with Ocular Hypertension.
Reyes-Resina I, Awad Alkozi H, Del Ser-Badia A, Sánchez-Naves J, Lillo J, Jiménez J, Pintor J, Navarro G, Franco R., Free PMC Article | 02/6/2021 |
| Age Associated Decrease of MT-1 Melatonin Receptor in Human Dermal Skin Fibroblasts Impairs Protection Against UV-Induced DNA Damage. | Age Associated Decrease of MT-1 Melatonin Receptor in Human Dermal Skin Fibroblasts Impairs Protection Against UV-Induced DNA Damage.
Dong K, Goyarts E, Rella A, Pelle E, Wong YH, Pernodet N., Free PMC Article | 09/12/2020 |
| Expression and prognostic significance of melatonin receptor MT1 in patients with gastric adenocarcinoma. | Expression and prognostic significance of melatonin receptor MT1 in patients with gastric adenocarcinoma.
Wang XT, Chen CW, Zheng XM, Wang B, Zhang SX, Yao MH, Chen H, Huang HF. | 08/22/2020 |
| There is substantial evidence indicating a role for MT1 receptor in modulating brain function and mood. [review] | Melatonin MT(1) receptor as a novel target in neuropsychopharmacology: MT(1) ligands, pathophysiological and therapeutic implications, and perspectives.
Comai S, Lopez-Canul M, De Gregorio D, Posner A, Ettaoussi M, Guarnieri FC, Gobbi G. | 03/28/2020 |
| high-resolution room-temperature X-ray free electron laser (XFEL) structures of MT1 in complex with four agonists: the insomnia drug ramelteon, two melatonin analogues, and the mixed melatonin-serotonin antidepressant agomelatine | Structural basis of ligand recognition at the human MT(1) melatonin receptor.
Stauch B, Johansson LC, McCorvy JD, Patel N, Han GW, Huang XP, Gati C, Batyuk A, Slocum ST, Ishchenko A, Brehm W, White TA, Michaelian N, Madsen C, Zhu L, Grant TD, Grandner JM, Shiriaeva A, Olsen RHJ, Tribo AR, Yous S, Stevens RC, Weierstall U, Katritch V, Roth BL, Liu W, Cherezov V., Free PMC Article | 01/25/2020 |
| results indicate melatonin 1 and GLUT1 as potential targets for breast cancer subtypes and prognosis | Immunohistochemical Expression of Melatonin Receptor MT1 and Glucose Transporter GLUT1 in Human Breast Cancer.
de Castro TB, Mota AL, Bordin-Junior NA, Neto DS, Zuccari DAPC. | 08/31/2019 |
| the TT genotype at the rs2119882 site was the key protective factor for obesityPolycystic ovary syndrome (PCOS) patients. Our study found that MTNR1A rs2119882 and MTNR1B rs10830963 could increase the risk for PCOS and cause glycolipid metabolism disorder in PCOS patients. | Genetic polymorphisms of melatonin receptors 1A and 1B may result in disordered lipid metabolism in obese patients with polycystic ovary syndrome.
Xu XH, Kou LC, Wang HM, Bo CM, Song XC., Free PMC Article | 05/25/2019 |
| Findings suggest variation close to MTNR1A as a risk factor for Alzheimer's disease in old age. The genetic associations are likely to be mediated by differences in MTNR1A expression, which, in turn, modulate APP metabolism. | Melatonin receptor type 1A gene linked to Alzheimer's disease in old age.
Sulkava S, Muggalla P, Sulkava R, Ollila HM, Peuralinna T, Myllykangas L, Kaivola K, Stone DJ, Traynor BJ, Renton AE, Rivera AM, Helisalmi S, Soininen H, Polvikoski T, Hiltunen M, Tienari PJ, Huttunen HJ, Paunio T., Free PMC Article | 04/6/2019 |
| this study evaluated the expression of MT1 receptor gene in gastric adenocarcinoma tissues which consistent with our previous study but with some difference in comparisons between kind of tissue expression and difference in polymorphisms. | Expression of MT1 receptor in patients with gastric adenocarcinoma and its relationship with clinicopathological features.
Nasrabadi NN, Sargazi F, Shokrzadeh M, Abediankenari S, Hoseini SV, Najafi M, Haghi-Aminjan H, Mirmajidi SH, Ataee R. | 01/26/2019 |
| we provide evidence that decreased expression of MTNR1A (MT1 ) in the liver of diabetic individuals is associated with poorly controlled diabetes | Nocturnal activation of melatonin receptor type 1 signaling modulates diurnal insulin sensitivity via regulation of PI3K activity.
Owino S, Sánchez-Bretaño A, Tchio C, Cecon E, Karamitri A, Dam J, Jockers R, Piccione G, Noh HL, Kim T, Kim JK, Baba K, Tosini G., Free PMC Article | 09/1/2018 |
| polymorphic genotypes of rs6553010 of MTNR1A might contribute to the ability to predict aggressive phenotypes of UCC. This is the first study to provide insights into risk factors associated with intronic MTNR1A variants in the clinicopathologic development of UCC in Taiwan. | Genetic Variations of Melatonin Receptor Type 1A are Associated with the Clinicopathologic Development of Urothelial Cell Carcinoma.
Lin YW, Wang SS, Wen YC, Tung MC, Lee LM, Yang SF, Chien MH., Free PMC Article | 06/30/2018 |