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    MSR1 macrophage scavenger receptor 1 [ Homo sapiens (human) ]

    Gene ID: 4481, updated on 17-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Role of macrophage scavenger receptor 1 in the progression of dyslipidemia in acne vulgaris patients.

    Role of macrophage scavenger receptor 1 in the progression of dyslipidemia in acne vulgaris patients.
    AbdElneam AI, Al-Dhubaibi MS, Bahaj SS, Mohammed GF., Free PMC Article

    08/31/2023
    Toll-like receptor 4 and macrophage scavenger receptor 1 crosstalk regulates phagocytosis of a fungal pathogen.

    Toll-like receptor 4 and macrophage scavenger receptor 1 crosstalk regulates phagocytosis of a fungal pathogen.
    Onyishi CU, Desanti GE, Wilkinson AL, Lara-Reyna S, Frickel EM, Fejer G, Christophe OD, Bryant CE, Mukhopadhyay S, Gordon S, May RC., Free PMC Article

    08/16/2023
    Scavenger receptor a mediates glycated LDL transcytosis across endothelial cells to promote atherosclerosis.

    Scavenger receptor a mediates glycated LDL transcytosis across endothelial cells to promote atherosclerosis.
    Cheng W, Shu M, Kuang L, Bai X, Jia X, Zhao Y, Lu Y, Zhu L, Wang L, Zhu Y, Shu Y, Song Y, Jin S.

    08/11/2023
    Comprehensive analysis of immune cell infiltration and role of MSR1 expression in aneurysmal subarachnoid haemorrhage.

    Comprehensive analysis of immune cell infiltration and role of MSR1 expression in aneurysmal subarachnoid haemorrhage.
    Wang X, Wen D, You C, Tao C, Ma L., Free PMC Article

    06/26/2023
    Role of macrophage scavenger receptor MSR1 in the progression of non-alcoholic steatohepatitis.

    Role of macrophage scavenger receptor MSR1 in the progression of non-alcoholic steatohepatitis.
    Sheng W, Ji G, Zhang L., Free PMC Article

    01/14/2023
    MSR1 characterized by chromatin accessibility mediates M2 macrophage polarization to promote gastric cancer progression.

    MSR1 characterized by chromatin accessibility mediates M2 macrophage polarization to promote gastric cancer progression.
    Chen X, Jiang J, Liu H, Li A, Wang W, Ni Z, Lin M.

    10/29/2022
    Comprehensive analysis of the prognostic and role in immune cell infiltration of MSR1 expression in lower-grade gliomas.

    Comprehensive analysis of the prognostic and role in immune cell infiltration of MSR1 expression in lower-grade gliomas.
    Ji Q, Huang K, Jiang Y, Lei K, Tu Z, Luo H, Zhu X., Free PMC Article

    05/21/2022
    MSR1 and NEP Are Correlated with Alzheimer's Disease Amyloid Pathology and Apolipoprotein Alterations.

    MSR1 and NEP Are Correlated with Alzheimer's Disease Amyloid Pathology and Apolipoprotein Alterations.
    Miron J, Picard C, Labonté A, Auld D, Poirier J, PREVENT-AD research group.

    04/16/2022
    Blocking Msr1 by berberine alkaloids inhibits caspase-11-dependent coagulation in bacterial sepsis.

    Blocking Msr1 by berberine alkaloids inhibits caspase-11-dependent coagulation in bacterial sepsis.
    Yuan C, Wu M, Xiao Q, Zhao W, Li H, Zhong Y, Zhao M, Li C, Li Y, Yang X., Free PMC Article

    03/26/2022
    CD8-positive T cells and CD204-positive M2-like macrophages predict postoperative prognosis of very high-risk prostate cancer.

    CD8-positive T cells and CD204-positive M2-like macrophages predict postoperative prognosis of very high-risk prostate cancer.
    Yanai Y, Kosaka T, Mikami S, Hongo H, Yasumizu Y, Takeda T, Matsumoto K, Miyauchi J, Kitano S, Oya M., Free PMC Article

    02/26/2022
    Determinants of Disease Penetrance in PRPF31-Associated Retinopathy.

    Determinants of Disease Penetrance in PRPF31-Associated Retinopathy.
    McLenachan S, Zhang D, Grainok J, Zhang X, Huang Z, Chen SC, Zaw K, Lima A, Jennings L, Roshandel D, Moon SY, Heath Jeffery RC, Attia MS, Thompson JA, Lamey TM, McLaren TL, De Roach J, Fletcher S, Chen FK., Free PMC Article

    02/12/2022
    Mapping the serum proteome to neurological diseases using whole genome sequencing.

    Mapping the serum proteome to neurological diseases using whole genome sequencing.
    Png G, Barysenka A, Repetto L, Navarro P, Shen X, Pietzner M, Wheeler E, Wareham NJ, Langenberg C, Tsafantakis E, Karaleftheri M, Dedoussis G, Mälarstig A, Wilson JF, Gilly A, Zeggini E., Free PMC Article

    01/8/2022
    SARS-CoV-2 spike protein alleviates atherosclerosis by suppressing macrophage lipid uptake through regulating R-loop formation on MSR1 mRNA.

    SARS-CoV-2 spike protein alleviates atherosclerosis by suppressing macrophage lipid uptake through regulating R-loop formation on MSR1 mRNA.
    Zhao W, Wang Z, Chen W, Chen M, Han J, Yin X, Hu X, Wang S, Zan J, Zheng L., Free PMC Article

    10/16/2021
    High-Expressed Macrophage Scavenger Receptor 1 Predicts Severity Clinical Outcome in Transplant Patient in Idiopathic Pulmonary Fibrosis Disease.

    High-Expressed Macrophage Scavenger Receptor 1 Predicts Severity Clinical Outcome in Transplant Patient in Idiopathic Pulmonary Fibrosis Disease.
    Zheng M, Tian T, Liang J, Ye S, Chen J, Ji Y., Free PMC Article

    10/16/2021
    Endocytosis by macrophages: interplay of macrophage scavenger receptor-1 and LDL receptor-related protein-1.

    Endocytosis by macrophages: interplay of macrophage scavenger receptor-1 and LDL receptor-related protein-1.
    Béguin EP, Przeradzka MA, Janssen EFJ, Meems H, Sedek M, van der Zwaan C, Mertens K, van den Biggelaar M, Meijer AB, Mourik MJ., Free PMC Article

    05/8/2021
    Sirt6 deletion in bone marrow-derived cells increases atherosclerosis - Central role of macrophage scavenger receptor 1.

    Sirt6 deletion in bone marrow-derived cells increases atherosclerosis - Central role of macrophage scavenger receptor 1.
    Arsiwala T, Pahla J, van Tits LJ, Bisceglie L, Gaul DS, Costantino S, Miranda MX, Nussbaum K, Stivala S, Blyszczuk P, Weber J, Tailleux A, Stein S, Paneni F, Beer JH, Greter M, Becher B, Mostoslavsky R, Eriksson U, Staels B, Auwerx J, Hottiger MO, Lüscher TF, Matter CM.

    01/23/2021
    Clinical and transcriptional signatures of human CD204 reveal an applicable marker for the protumor phenotype of tumor-associated macrophages in breast cancer.

    Clinical and transcriptional signatures of human CD204 reveal an applicable marker for the protumor phenotype of tumor-associated macrophages in breast cancer.
    He Y, Zhou S, Deng F, Zhao S, Chen W, Wang D, Chen X, Hou J, Zhang J, Zhang W, Ding L, Tang J, Zhou Z., Free PMC Article

    10/10/2020
    SRA stimulation lead to selective ERK phosphorylation, which upregulated cytosol reactive oxygen species levels and induced canonical neutrophil extracellular traps formation by activating NADPH oxidase 2 (NOX2).

    Stimulation of the class-A scavenger receptor induces neutrophil extracellular traps (NETs) by ERK dependent NOX2 and ROMO1 activation.
    Zhu Y, Yang Y, Li F, Fan S, Chen X, Lu Y, Wei Y, Chen Q, Xia L, Tang J, Huang Q, Zhu Q, Zheng J, Liu X.

    01/18/2020
    MSR1 K63 polyubiquitylation correlated with the activation of JNK signalling in ovarian cancer tissue from human patients, suggesting that it may be relevant for macrophage phenotypic shift in vivo. MSR1 signals through JNK via K63 polyubiquitylation and is involved in macrophage polarization.

    Triggering MSR1 promotes JNK-mediated inflammation in IL-4-activated macrophages.
    Guo M, Härtlova A, Gierliński M, Prescott A, Castellvi J, Losa JH, Petersen SK, Wenzel UA, Dill BD, Emmerich CH, Ramon Y Cajal S, Russell DG, Trost M., Free PMC Article

    01/11/2020
    identified SR-AI as a novel macrophage-specific receptor for von Willebrand factor. Enhanced binding of von Willebrand factor mutants to SR-AI may contribute to the increased clearance of these mutants.

    Macrophage scavenger receptor SR-AI contributes to the clearance of von Willebrand factor.
    Wohner N, Muczynski V, Mohamadi A, Legendre P, Proulle V, Aymé G, Christophe OD, Lenting PJ, Denis CV, Casari C., Free PMC Article

    07/20/2019
    Results provide evidence that CD204 (+) tumor-associated macrophages is a novel component in the malignant transformation of colorectal adenoma.

    CD204-Positive Tumor-associated Macrophages Relate to Malignant Transformation of Colorectal Adenoma.
    Taniyama D, Taniyama K, Kuraoka K, Yamamoto H, Zaitsu J, Saito A, Sakamoto N, Sentani K, Oue N, Yasui W.

    06/22/2019
    The expression of CD204 in tumor-associated macrophages is associated with the aggressiveness of lung adenocarcinoma.

    Tumor-Associated CD204-Positive Macrophage Is a Prognostic Marker in Clinical Stage I Lung Adenocarcinoma.
    Sun Y, Xu S., Free PMC Article

    10/6/2018
    Decreased expression by OxLDL in PMA-differentiated THP-1 macrophages. Increased expression in plaque vs. nonplaque lesion areas in human carotid endarterectomy specimens (correlated with CD36 expression).

    CD36 is significantly correlated with adipophilin in human carotid lesions and inversely correlated with plasma ApoAI.
    Collot-Teixeira S, Barbatis C, Bultelle F, Koutouzis M, Pasterkamp G, Fraser P, Kyriakides ZS, Poston RN, Ristagno A, McGregor L, Boulanger CM, Leseche G, McGregor JL., Free PMC Article

    07/3/2018
    Cytokine abnormality induced by SRA(+) cells playS an role in tissue injury, and platelet emboli or contraction band necrosis might have been the leading cause of death in our SUDI cases.

    Biochemical, cytological and histopathological examination of sudden unexpected death in infancy.
    Emura I, Usuda H.

    07/3/2018
    TGM2 has a role in macrophage differentiation via mechanisms involving CD14 and SR-AI receptors.

    Inhibition of transglutaminase 2 reduces efferocytosis in human macrophages: Role of CD14 and SR-AI receptors.
    Eligini S, Fiorelli S, Tremoli E, Colli S.

    07/3/2018
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