| CircEXOC6B Suppresses the Proliferation and Motility and Sensitizes Ovarian Cancer Cells to Paclitaxel Through miR-376c-3p/FOXO3 Axis. | CircEXOC6B Suppresses the Proliferation and Motility and Sensitizes Ovarian Cancer Cells to Paclitaxel Through miR-376c-3p/FOXO3 Axis.
Zheng Y, Li Z, Yang S, Wang Y, Luan Z. | 11/26/2022 |
| Loading MicroRNA-376c in Extracellular Vesicles Inhibits Properties of Non-Small Cell Lung Cancer Cells by Targeting YTHDF1. | Loading MicroRNA-376c in Extracellular Vesicles Inhibits Properties of Non-Small Cell Lung Cancer Cells by Targeting YTHDF1.
Zhou J, Xiao D, Qiu T, Li J, Liu Z., Free PMC Article | 11/27/2021 |
| Age-Related Changes in miRNA Expression Influence GSTZ1 and Other Drug Metabolizing Enzymes. | Age-Related Changes in miRNA Expression Influence GSTZ1 and Other Drug Metabolizing Enzymes.
Jahn SC, Gay LA, Weaver CJ, Renne R, Langaee TY, Stacpoole PW, James MO., Free PMC Article | 09/11/2021 |
| The data suggest that miR-376c-3p downregulated ING5 to exert protective effects against oxygen-glucose deprivation-induced cell injury in cultured human and rat cells. | Upregulation of miR-376c-3p alleviates oxygen-glucose deprivation-induced cell injury by targeting ING5.
Zhang H, Zhou J, Zhang M, Yi Y, He B., Free PMC Article | 05/16/2020 |
| we have identified miR-376c-3p as a TWIST-1-regulated miRNA, which plays an important role in the osteogenesis of bone precursor cells and can mediate TWIST-1 inhibition of osteogenesis. | miRNA-376c-3p Mediates TWIST-1 Inhibition of Bone Marrow-Derived Stromal Cell Osteogenesis and Can Reduce Aberrant Bone Formation of TWIST-1 Haploinsufficient Calvarial Cells.
Camp E, Pribadi C, Anderson PJ, Zannettino ACW, Gronthos S. | 10/5/2019 |
| that DLX6-AS1 may contribute to preeclampsia by impairing proliferative, migratory and invasive abilities of trophoblasts via the miR-376c/GADD45A axis | Long non-coding RNA DLX6-AS1 is upregulated in preeclampsia and modulates migration and invasion of trophoblasts through the miR-376c/GADD45A axis.
Tan Y, Xiao D, Xu Y, Wang C. | 10/5/2019 |
| over-expression of miR-638 inhibited the activation of Wnt/beta-catenin signaling pathway. | MiR-638 inhibits cervical cancer metastasis through Wnt/β-catenin signaling pathway and correlates with prognosis of cervical cancer patients.
Wei H, Zhang JJ, Tang QL. | 08/24/2019 |
| MiR-376c-3p suppresses the fission, proliferation, migration and invasion and induces cell apoptosis of oral squamous cancer cells via targeting HOXB7. | MiR-376c-3p regulates the proliferation, invasion, migration, cell cycle and apoptosis of human oral squamous cancer cells by suppressing HOXB7.
Wang K, Jin J, Ma T, Zhai H. | 03/31/2018 |
| TSP-2 enhances the migration of PCa cells by increasing MMP-2 expression through down-regulation of miR-376c expression. | Thrombospondin-2 promotes prostate cancer bone metastasis by the up-regulation of matrix metalloproteinase-2 through down-regulating miR-376c expression.
Chen PC, Tang CH, Lin LW, Tsai CH, Chu CY, Lin TH, Huang YL., Free PMC Article | 12/16/2017 |
| results demonstrate that miR-376c functions by suppressing ARID4A expression, which in turn enhances the oncogenicity of gastric carcinoma cells. It seems likely that the level of miR-376c in plasma and urine could act as invaluable markers for the detection of gastric carcinoma | miR-376c promotes carcinogenesis and serves as a plasma marker for gastric carcinoma.
Hung PS, Chen CY, Chen WT, Kuo CY, Fang WL, Huang KH, Chiu PC, Lo SS., Free PMC Article | 09/30/2017 |
| newly identified miR-376c/BMI1 pathway provides an insight into cervical cancer progression | miR-376c inhibits cervical cancer cell proliferation and invasion by targeting BMI1.
Deng Y, Xiong Y, Liu Y., Free PMC Article | 08/5/2017 |
| our results defined a novel pathway in which dysregulation of the RUNX2/INHBA axis due to miR-376c downregulation fosters lymph node metastasis in head and neck squamous cell carcinoma | Dysregulation of RUNX2/Activin-A Axis upon miR-376c Downregulation Promotes Lymph Node Metastasis in Head and Neck Squamous Cell Carcinoma.
Chang WM, Lin YF, Su CY, Peng HY, Chang YC, Lai TC, Wu GH, Hsu YM, Chi LH, Hsiao JR, Chen CL, Chang JY, Shieh YS, Hsiao M, Shiah SG. | 07/29/2017 |
| miR-376c inhibits non-small-cell lung cancer cell growth and invasion by targeting LRH-1 | MicroRNA-376c suppresses non-small-cell lung cancer cell growth and invasion by targeting LRH-1-mediated Wnt signaling pathway.
Jiang W, Tian Y, Jiang S, Liu S, Zhao X, Tian D. | 06/24/2017 |
| miR-376c is inversely linked to UGT2B15 and UGT2B17 expression in high-grade prostate cancer and metastasis.UGT2B15 and UGT2B17 genes are direct targets of miR-376c and thus may influence steroid metabolism during prostate cancer progression. | Epigenetic regulation of steroid inactivating UDP-glucuronosyltransferases by microRNAs in prostate cancer.
Margaillan G, Lévesque É, Guillemette C. | 05/7/2016 |
| Expression of UGT2B15 and UGT2B17 is negatively regulated by the binding of miR-376c. | Regulation of Human UGT2B15 and UGT2B17 by miR-376c in Prostate Cancer Cell Lines.
Wijayakumara DD, Hu DG, Meech R, McKinnon RA, Mackenzie PI. | 10/10/2015 |
| miR-638 plays an important role in triple-negative breast cancer progression via BRCA1 deregulation. | miR-638 mediated regulation of BRCA1 affects DNA repair and sensitivity to UV and cisplatin in triple-negative breast cancer.
Tan X, Peng J, Fu Y, An S, Rezaei K, Tabbara S, Teal CB, Man YG, Brem RF, Fu SW., Free PMC Article | 08/1/2015 |
| Mir-376c, mapped to the 14q32.31 locus, regulates proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells. | MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells.
Formosa A, Markert EK, Lena AM, Italiano D, Finazzi-Agro' E, Levine AJ, Bernardini S, Garabadgiu AV, Melino G, Candi E. | 05/2/2015 |
| Epigenetic repression of miR-376c accelerated EGF-dependent cell migration through its target GRB2 in HuCCT1 cells. | MiR-376c down-regulation accelerates EGF-dependent migration by targeting GRB2 in the HuCCT1 human intrahepatic cholangiocarcinoma cell line.
Iwaki J, Kikuchi K, Mizuguchi Y, Kawahigashi Y, Yoshida H, Uchida E, Takizawa T., Free PMC Article | 04/1/2015 |
| microRNA 376c (miR-376c) significantly enhanced neural differentiation of hPSCs in a defined condition by suppressing SMAD4 | A reciprocal antagonism between miR-376c and TGF-β signaling regulates neural differentiation of human pluripotent stem cells.
Liu J, Wang L, Su Z, Wu W, Cai X, Li D, Hou J, Pei D, Pan G. | 01/31/2015 |
| miR-376c levels were differentially expressed by race and PAR4 reactivity and were inversely correlated with PCTP mRNA levels, PC-TP protein levels and PAR4 reactivity. | Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c.
Edelstein LC, Simon LM, Montoya RT, Holinstat M, Chen ES, Bergeron A, Kong X, Nagalla S, Mohandas N, Cohen DE, Dong JF, Shaw C, Bray PF., Free PMC Article | 03/1/2014 |
| the role of miR-376c in regulating osteosarcoma cell growth via miR-376c/TGF-alpha axis | MicroRNA-376c inhibits cell proliferation and invasion in osteosarcoma by targeting to transforming growth factor-alpha.
Jin Y, Peng D, Shen Y, Xu M, Liang Y, Xiao B, Lu J. | 08/31/2013 |
| Upregulation of plasma MIR376C is associated with breast cancer. | Circulating microRNAs in plasma as early detection markers for breast cancer.
Cuk K, Zucknick M, Heil J, Madhavan D, Schott S, Turchinovich A, Arlt D, Rath M, Sohn C, Benner A, Junkermann H, Schneeweiss A, Burwinkel B. | 04/6/2013 |
| down-regulation of mir-376a and mir-376c may contribute to IGF1R over-expression and to aberrant negative regulation of this signaling pathway in melanoma, thus promoting tumorigenesis and metastasis. | Silencing of a large microRNA cluster on human chromosome 14q32 in melanoma: biological effects of mir-376a and mir-376c on insulin growth factor 1 receptor.
Zehavi L, Avraham R, Barzilai A, Bar-Ilan D, Navon R, Sidi Y, Avni D, Leibowitz-Amit R., Free PMC Article | 12/22/2012 |
| miR-376c promotes ovarian cancer cell proliferation,survival and spheroid formation | MicroRNA 376c enhances ovarian cancer cell survival by targeting activin receptor-like kinase 7: implications for chemoresistance.
Ye G, Fu G, Cui S, Zhao S, Bernaudo S, Bai Y, Ding Y, Zhang Y, Yang BB, Peng C. | 08/6/2011 |