| cDCBLD2 mediates sorafenib resistance in hepatocellular carcinoma by sponging miR-345-5p binding to the TOP2A coding sequence. | cDCBLD2 mediates sorafenib resistance in hepatocellular carcinoma by sponging miR-345-5p binding to the TOP2A coding sequence.
Ruan Y, Chen T, Zheng L, Cai J, Zhao H, Wang Y, Tao L, Xu J, Ji L, Cai X., Free PMC Article | 10/4/2023 |
| miR-345-5p curbs hepatic stellate cell activation and liver fibrosis progression by suppressing hypoxia-inducible factor-1alpha expression. | miR-345-5p curbs hepatic stellate cell activation and liver fibrosis progression by suppressing hypoxia-inducible factor-1alpha expression.
Wang P, Fang Y, Qiu J, Zhou Y, Wang Z, Jiang C. | 10/22/2022 |
| Circular RNA Circ-STIL Contributes to Cell Growth and Metastasis in Hepatocellular Carcinoma via Regulating miR-345-5p/AQP3 Axis. | Circular RNA Circ-STIL Contributes to Cell Growth and Metastasis in Hepatocellular Carcinoma via Regulating miR-345-5p/AQP3 Axis.
Liu J, He X, Zou Y, Wang K. | 06/11/2022 |
| The miR-345-3p/PPP2CA signaling axis promotes proliferation and invasion of breast cancer cells. | The miR-345-3p/PPP2CA signaling axis promotes proliferation and invasion of breast cancer cells.
Zeng Q, Jin F, Qian H, Chen H, Wang Y, Zhang D, Wei Y, Chen T, Guo B, Chai C., Free PMC Article | 05/14/2022 |
| Long non-coding RNA RACGAP1P promotes breast cancer invasion and metastasis via miR-345-5p/RACGAP1-mediated mitochondrial fission. | Long non-coding RNA RACGAP1P promotes breast cancer invasion and metastasis via miR-345-5p/RACGAP1-mediated mitochondrial fission.
Zhou D, Ren K, Wang M, Wang J, Li E, Hou C, Su Y, Jin Y, Zou Q, Zhou P, Liu X., Free PMC Article | 11/27/2021 |
| Upregulation of miR-345-5p suppresses cell growth of lung adenocarcinoma by regulating ras homolog family member A (RhoA) and Rho/Rho associated protein kinase (Rho/ROCK) pathway. | Upregulation of miR-345-5p suppresses cell growth of lung adenocarcinoma by regulating ras homolog family member A (RhoA) and Rho/Rho associated protein kinase (Rho/ROCK) pathway.
Zhou QY, Gui SY, Zhang P, Wang M., Free PMC Article | 11/22/2021 |
| Osteoporosis genome-wide association study variant c.3781 C>A is regulated by a novel anti-osteogenic factor miR-345-5p. | Osteoporosis genome-wide association study variant c.3781 C>A is regulated by a novel anti-osteogenic factor miR-345-5p.
Wang Y, Ye W, Liu Y, Mei B, Liu X, Huang Q. | 07/24/2021 |
| LncRNA DANCR affected cell growth, EMT and angiogenesis by sponging miR-345-5p through modulating Twist1 in cholangiocarcinoma. | LncRNA DANCR affected cell growth, EMT and angiogenesis by sponging miR-345-5p through modulating Twist1 in cholangiocarcinoma.
Zhu CY, Fan CR, Zhang YL, Sun QX, Yan MJ, Wei W, Liu GF, Liu JJ. | 03/20/2021 |
| MicroRNA 345 (miR345) regulates KISS1-E-cadherin functional interaction in breast cancer brain metastases. | MicroRNA 345 (miR345) regulates KISS1-E-cadherin functional interaction in breast cancer brain metastases.
Ulasov I, Borovjagin A, Fares J, Yakushov S, Malin D, Timashev P, Lesniak MS. | 12/19/2020 |
| miR-345 inhibits migration and stem-like cell phenotype in gastric cancer via inactivation of Rac1 by targeting EPS8. | miR-345 inhibits migration and stem-like cell phenotype in gastric cancer via inactivation of Rac1 by targeting EPS8.
Zhang J, Wang C, Yan S, Yang Y, Zhang X, Guo W. | 12/19/2020 |
| MicroRNA-345 functions as a tumor suppressor via targeting ZEB2 in oral squamous cell carcinoma. | MicroRNA-345 functions as a tumor suppressor via targeting ZEB2 in oral squamous cell carcinoma.
Wu J, Cao J, Li X, Wu B, Zhang S. | 10/31/2020 |
| MicroRNA-345 suppresses cell invasion and migration in non-small cell lung cancer by directly targeting YAP1. | MicroRNA-345 suppresses cell invasion and migration in non-small cell lung cancer by directly targeting YAP1.
Zhang MY, Lin J, Kui YC. | 08/13/2020 |
| Our study demonstrated that TMS reduced gefitinib resistance in NSCLCs via suppression of the MAPK/Akt/Bcl-2 pathway by upregulation of miR-345/498. | Trans-3,5,4´-trimethoxystilbene reduced gefitinib resistance in NSCLCs via suppressing MAPK/Akt/Bcl-2 pathway by upregulation of miR-345 and miR-498.
Lu M, Liu B, Xiong H, Wu F, Hu C, Liu P., Free PMC Article | 07/11/2020 |
| MiR-345-3p prevented oxLDL-induced apoptosis and inflammation through the TAK1/p38/NF-kappaB pathway via targeting TRAF6 | MiR-345-3p attenuates apoptosis and inflammation caused by oxidized low-density lipoprotein by targeting TRAF6 via TAK1/p38/NF-kB signaling in endothelial cells.
Wei Q, Tu Y, Zuo L, Zhao J, Chang Z, Zou Y, Qiu J. | 01/25/2020 |
| MiR-345-5p was a tumor-suppressive miRNA in pancreatic cancer progression by targeting CCL8. | MiR-345-5p functions as a tumor suppressor in pancreatic cancer by directly targeting CCL8.
Mou T, Xie F, Zhong P, Hua H, Lai L, Yang Q, Wang J. | 06/22/2019 |
| results set the stage for a further investigation on the potential application of circulating miR-345-5p as a biomarker for prostate cancer diagnosis and therapeutic response | Functional roles and potential clinical application of miRNA-345-5p in prostate cancer.
Tinay I, Tan M, Gui B, Werner L, Kibel AS, Jia L. | 06/1/2019 |
| MiR-345 was found to be decreased in gastric cancer (GC) tissues and cell lines and associated with adverse clinical features and unfavorable prognosis of GC patients. Functionally, miR-345 inhibited the metastasis of GC cells both in vitro and in vivo. miR-345 was found to inhibit epithelial-mesenchymal transition of GC cells. | MicroRNA-345 inhibits metastasis and epithelial-mesenchymal transition of gastric cancer by targeting FOXQ1.
Feng A, Yuan X, Li X., Free PMC Article | 07/28/2018 |
| let-7b-5p and miR-345-5p as promising blood-derived disease biomarkers in Multiple Sclerosis. | Analysis of microRNA and Gene Expression Profiles in Multiple Sclerosis: Integrating Interaction Data to Uncover Regulatory Mechanisms.
Freiesleben S, Hecker M, Zettl UK, Fuellen G, Taher L., Free PMC Article | 06/16/2018 |
| YAP1 overexpression reversed the inhibitory effects of miR-345 on MHCC-97H migration and invasion, while YAP1 knockdown reduced the promoting effects of miR-345 knockdown on the metastatic behavior of Hep3B cells. | MicroRNA-345 inhibits hepatocellular carcinoma metastasis by inhibiting YAP1.
Zhang H, Liu H, Bi H., Free PMC Article | 06/2/2018 |
| Circulating serum miR-345 correlates with unfavorable preoperative chemoradiotherapy response and poor locoregional control in locally advanced rectal cancer. | Circulating serum microRNA-345 correlates with unfavorable pathological response to preoperative chemoradiotherapy in locally advanced rectal cancer.
Yu J, Li N, Wang X, Ren H, Wang W, Wang S, Song Y, Liu Y, Li Y, Zhou X, Luo A, Liu Z, Jin J., Free PMC Article | 02/10/2018 |
| MiR-345 downregulation confers apoptosis resistance to PC cells. | MicroRNA-345 induces apoptosis in pancreatic cancer cells through potentiation of caspase-dependent and -independent pathways.
Srivastava SK, Bhardwaj A, Arora S, Tyagi N, Singh S, Andrews J, McClellan S, Wang B, Singh AP., Free PMC Article | 10/31/2015 |
| miR-345 in whole blood as a potential biomarker for clinical outcome in in non-KRAS mutant colorectal cancer patients. | miR-345 in metastatic colorectal cancer: a non-invasive biomarker for clinical outcome in non-KRAS mutant patients treated with 3rd line cetuximab and irinotecan.
Schou JV, Rossi S, Jensen BV, Nielsen DL, Pfeiffer P, Høgdall E, Yilmaz M, Tejpar S, Delorenzi M, Kruhøffer M, Johansen JS., Free PMC Article | 07/4/2015 |
| Down regulation of MicroRNA 345 is associated with colorectal cancer. | MicroRNA 345, a methylation-sensitive microRNA is involved in cell proliferation and invasion in human colorectal cancer.
Tang JT, Wang JL, Du W, Hong J, Zhao SL, Wang YC, Xiong H, Chen HM, Fang JY. | 10/1/2011 |