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    MOS MOS proto-oncogene, serine/threonine kinase [ Homo sapiens (human) ]

    Gene ID: 4342, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    MOS mutation causes female infertility with large polar body oocytes.

    MOS mutation causes female infertility with large polar body oocytes.
    Jiao G, Lian H, Xing J, Chen L, Du Z, Liu X.

    03/6/2023
    approach identified 18 kinase and kinase-related genes whose overexpression can substitute for EGFR in EGFR-dependent PC9 cells, and these genes include seven of nine Src family kinase genes, FGFR1, FGFR2, ITK, NTRK1, NTRK2, MOS, MST1R, and RAF1.

    Genetic modifiers of EGFR dependence in non-small cell lung cancer.
    Sharifnia T, Rusu V, Piccioni F, Bagul M, Imielinski M, Cherniack AD, Pedamallu CS, Wong B, Wilson FH, Garraway LA, Altshuler D, Golub TR, Root DE, Subramanian A, Meyerson M., Free PMC Article

    04/25/2015
    High methylation level in MOS is associated with intestinal metaplasia.

    Changes in aberrant DNA methylation after Helicobacter pylori eradication: a long-term follow-up study.
    Shin CM, Kim N, Lee HS, Park JH, Ahn S, Kang GH, Kim JM, Kim JS, Lee DH, Jung HC.

    11/2/2013
    among the candidate genes, DNA methylation of MOS may reflect the duration of H. pylori exposure and may be a marker for the development of gastric cancer.

    Prediction of the risk for gastric cancer using candidate methylation markers in the non-neoplastic gastric mucosae.
    Shin CM, Kim N, Park JH, Kang GH, Kim JS, Jung HC, Song IS.

    03/24/2012
    Observational study of gene-disease association. (HuGE Navigator)

    The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.
    Zhao J, Li M, Bradfield JP, Zhang H, Mentch FD, Wang K, Sleiman PM, Kim CE, Glessner JT, Hou C, Keating BJ, Thomas KA, Garris ML, Deliard S, Frackelton EC, Otieno FG, Chiavacci RM, Berkowitz RI, Hakonarson H, Grant SF., Free PMC Article

    09/15/2010
    In the absence of p53, Mos knockdown prevents multipolar mitoses and exerts genome-stabilizing effects.

    Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos.
    Vitale I, Senovilla L, Jemaà M, Michaud M, Galluzzi L, Kepp O, Nanty L, Criollo A, Rello-Varona S, Manic G, Métivier D, Vivet S, Tajeddine N, Joza N, Valent A, Castedo M, Kroemer G., Free PMC Article

    05/10/2010
    Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition

    Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition.
    Tang W, Wu JQ, Guo Y, Hansen DV, Perry JA, Freel CD, Nutt L, Jackson PK, Kornbluth S., Free PMC Article

    01/21/2010
    Mos 3' UTR regulatory differences underlie species-specific temporal patterns of Mos mRNA cytoplasmic polyadenylation and translational recruitment during oocyte maturation.

    Mos 3' UTR regulatory differences underlie species-specific temporal patterns of Mos mRNA cytoplasmic polyadenylation and translational recruitment during oocyte maturation.
    Prasad CK, Mahadevan M, MacNicol MC, MacNicol AM., Free PMC Article

    01/21/2010
    These results clarify the direct link of the classical Mos-MAPK (mitogen-activated protein kinase) pathway to Erp1 in meiotic arrest of vertebrate oocytes.

    A direct link of the Mos-MAPK pathway to Erp1/Emi2 in meiotic arrest of Xenopus laevis eggs.
    Inoue D, Ohe M, Kanemori Y, Nobui T, Sagata N.

    08/7/2008
    the Mos/MAPK pathway is not essential for initiating goldfish oocyte maturation despite its general function as a cytostatic factor (CSF).

    The Mos/MAPK pathway is involved in metaphase II arrest as a cytostatic factor but is neither necessary nor sufficient for initiating oocyte maturation in goldfish.
    Kajiura-Kobayashi H, Yoshida N, Sagata N, Yamashita M, Nagahama Y.

    08/7/2008
    multiple meiotic genes are aberrantly activated during mitotic catastrophe in p53 mutated lymphoma cells after irradiation; the coordinated expression of MOS and REC8 regulate the extent of arrested mitoses and polyploidy

    Upregulation of meiosis-specific genes in lymphoma cell lines following genotoxic insult and induction of mitotic catastrophe.
    Kalejs M, Ivanov A, Plakhins G, Cragg MS, Emzinsh D, Illidge TM, Erenpreisa J., Free PMC Article

    01/21/2010
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