| Although gastric cancer cell-invasive activity was significantly decreased by knockdown, forced expression of ASGR2 promoted invasive activity. | Pattern-Specific Transcriptomics Identifies ASGR2 as a Predictor of Hematogenous Recurrence of Gastric Cancer.
Tanaka H, Kanda M, Miwa T, Tanaka C, Kobayashi D, Umeda S, Shibata M, Suenaga M, Hattori N, Hayashi M, Iwata N, Yamada S, Nakayama G, Fujiwara M, Kodera Y. | 08/31/2019 |
| PEGylated lipoplexes were well tolerated by both HEK293 (ASGP-R-negative) and HepG2 (ASGP-R-positive) cell lines and delivered DNA to the hepatoma cell line HepG2 by ASGP-R mediation at levels three-fold greater than nonPEGylated lipoplexes. | PEGylation potentiates hepatoma cell targeted liposome-mediated in vitro gene delivery via the asialoglycoprotein receptor.
Mkhwanazi NK, de Koning CB, van Otterlo WAL, Ariatti M, Singh M. | 09/30/2017 |
| findings show that the hepatitis E virus (HEV) ORF2 protein interacts directly with the ectodomain of both ASGR1 and ASGR2; ASGPR is involved in and facilitates HEV infection by binding to ORF2 | Asialoglycoprotein receptor facilitates infection of PLC/PRF/5 cells by HEV through interaction with ORF2.
Zhang L, Tian Y, Wen Z, Zhang F, Qi Y, Huang W, Zhang H, Wang Y. | 08/12/2017 |
| the distribution of ASGR in human testis, was investigated. | Expression pattern of asialoglycoprotein receptor in human testis.
Sun P, Zheng J, She G, Wei X, Zhang X, Shi H, Zhou X. | 12/21/2013 |
| sH2a has the potential to be a uniquely sensitive and specific novel marker for liver fibrosis and function. | A secreted form of the asialoglycoprotein receptor, sH2a, as a novel potential noninvasive marker for liver fibrosis.
Veselkin E, Kondratyev M, Lurie Y, Ron E, Santo M, Reif S, Elashvili I, Bar L, Lederkremer GZ., Free PMC Article | 04/14/2012 |
| found that the asialoglycoprotein receptor (ASGPR) is involved in hepatocyte recognition of cells predestined for killing, including activated autologous T lymphocytes | Hepatocyte cytotoxicity is facilitated by asialoglycoprotein receptor.
Guy CS, Rankin SL, Michalak TI. | 02/11/2012 |
| Observational study of gene-disease association. (HuGE Navigator) | New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M. | 04/7/2010 |
| Exposure of beta-galactose results in the rapid clearance of platelets from the circulation by asialoglycoprotein receptor-expressing liver macrophages and hepatocytes. | Role of sialic acid for platelet life span: exposure of beta-galactose results in the rapid clearance of platelets from the circulation by asialoglycoprotein receptor-expressing liver macrophages and hepatocytes.
Sørensen AL, Rumjantseva V, Nayeb-Hashemi S, Clausen H, Hartwig JH, Wandall HH, Hoffmeister KM., Free PMC Article | 01/21/2010 |
| primary renal proximal tubular epithelial cells have a functional ASGPR, consisting of the H1 and H2 subunits, that is capable of specific ligand binding and uptake | Expression of a functional asialoglycoprotein receptor in human renal proximal tubular epithelial cells.
Seow YY, Tan MG, Woo KT. | 01/21/2010 |
| The minor subunit splice variants, H2b and H2c, of the human asialoglycoprotein receptor are present with the major subunit H1 in different hetero-oligomeric receptor complexes | The minor subunit splice variants, H2b and H2c, of the human asialoglycoprotein receptor are present with the major subunit H1 in different hetero-oligomeric receptor complexes.
Yik JH, Saxena A, Weigel PH. | 01/21/2010 |
| trafficks intracellularly and forms homo-oligomers, but does not bind asialo-orosomucoid | H2, the minor subunit of the human asialoglycoprotein receptor, trafficks intracellularly and forms homo-oligomers, but does not bind asialo-orosomucoid.
Saxena A, Yik JH, Weigel PH. | 01/21/2010 |