| MMP19 Variants in Familial and Sporadic Idiopathic Pulmonary Fibrosis. | MMP19 Variants in Familial and Sporadic Idiopathic Pulmonary Fibrosis.
Fan Y, Zheng C, Ma R, Wang J, Yang S, Ye Q. | 11/30/2023 |
| Endothelial cell-derived MMP19 promotes pulmonary fibrosis by inducing E(nd)MT and monocyte infiltration. | Endothelial cell-derived MMP19 promotes pulmonary fibrosis by inducing E(nd)MT and monocyte infiltration.
Zhao W, Wang L, Yang J, Chen X, Guo X, Xu K, Wang N, Zhao W, Xia C, Lian H, Rosas I, Yu G., Free PMC Article | 03/20/2023 |
| Potential novel markers in IBD and CRC diagnostics. Are MMP-19 and RAGE promising candidates? | Potential novel markers in IBD and CRC diagnostics. Are MMP-19 and RAGE promising candidates?
Horak P, Suhaj P, Matej R, Cervinkova M. | 01/11/2023 |
| Long noncoding RNA ZEB1-AS1 affects paclitaxel and cisplatin resistance by regulating MMP19 in epithelial ovarian cancer cells. | Long noncoding RNA ZEB1-AS1 affects paclitaxel and cisplatin resistance by regulating MMP19 in epithelial ovarian cancer cells.
Dai C, Xu P, Liu S, Xu S, Xu J, Fu Z, Cao J, Lv M, Zhou J, Liu G, Zhang H, Jia X. | 05/29/2021 |
| MicroRNA-16 inhibits the proliferation, migration and invasion of non-small cell lung carcinoma cells by down-regulating matrix metalloproteinase-19 expression. | MicroRNA-16 inhibits the proliferation, migration and invasion of non-small cell lung carcinoma cells by down-regulating matrix metalloproteinase-19 expression.
Tian G, Wang SW, Song M, Hu YF, Cao XN, Ge JW. | 10/3/2020 |
| Study found that the expression of MMP19 was upregulated in colorectal cancer (CRC). High expression of MMP19 was determined to be an independent and poor prognostic factor in CRC. These results suggest that MMP19 may be a good biomarker for CRC. | High expression of MMP19 is associated with poor prognosis in patients with colorectal cancer.
Chen Z, Wu G, Ye F, Chen G, Fan Q, Dong H, Zhu X, Wu C., Free PMC Article | 09/14/2019 |
| MiR-193b-3p is an important regulator of MMP-19 in human chondrocytes and may relieve the inflammatory response in OA. | MicroRNA-193b-3p regulates matrix metalloproteinase 19 expression in interleukin-1β-induced human chondrocytes.
Chang ZK, Meng FG, Zhang ZQ, Mao GP, Huang ZY, Liao WM, He AS. | 03/2/2019 |
| Levels of matrix metalloproteinases MMP-19 and MMP-20 expression are significantly increased in pancreatic ductal adenocarcinoma (PDAC). | High-Level Expression and Prognostic Significance of Matrix Metalloprotease-19 and Matrix Metalloprotease-20 in Human Pancreatic Ductal Adenocarcinoma.
Zhai LL, Wu Y, Cai CY, Huang Q, Tang ZG. | 04/1/2017 |
| transcriptional target of ligand-bound activated estrogen receptor beta acting on a specificity protein-1 binding site | Estrogen receptor β controls MMP-19 expression in mouse ovaries during ovulation.
Nalvarte I, Töhönen V, Lindeberg M, Varshney M, Gustafsson JÅ, Inzunza J. | 12/17/2016 |
| the downregulation of MMP19 following respiratory syncytial virus infection may be associated with the development of airway hyperresponsiveness. | Downregulation of matrix metalloproteinase‑19 induced by respiratory syncytial viral infection affects the interaction between epithelial cells and fibroblasts.
Wu X, Qi H, Yang Y, Yin Y, Ma D, Li H, Qu Y., Free PMC Article | 10/1/2016 |
| Loss of NDRG2 induced the expression of matrix metalloproteinase-19 (MMP-19), which regulated the expression of Slug at the transcriptional level in the epithelial-mesenchymal transition of gallbladder carcinoma cells. | Loss of NDRG2 promotes epithelial-mesenchymal transition of gallbladder carcinoma cells through MMP-19-mediated Slug expression.
Lee DG, Lee SH, Kim JS, Park J, Cho YL, Kim KS, Jo DY, Song IC, Kim N, Yun HJ, Park YJ, Lee SJ, Lee HG, Bae KH, Lee SC, Shim S, Kim YM, Kwon YG, Kim JM, Lee HJ, Min JK. | 09/17/2016 |
| Triplication of an enhancer may lead to overexpression of MMP19 in the optic nerve that causes cavitary optic disc anomaly. | Heterozygous triplication of upstream regulatory sequences leads to dysregulation of matrix metalloproteinase 19 in patients with cavitary optic disc anomaly.
Hazlewood RJ, Roos BR, Solivan-Timpe F, Honkanen RA, Jampol LM, Gieser SC, Meyer KJ, Mullins RF, Kuehn MH, Scheetz TE, Kwon YH, Alward WL, Stone EM, Fingert JH., Free PMC Article | 11/28/2015 |
| the intima+media of IPAH vessels, collagens (COL4A5, COL14A1, and COL18A1), matrix metalloproteinase (MMP) 19, and a disintegrin and metalloprotease (ADAM) 33 were higher expressed, whereas MMP10, ADAM17, TIMP1, and TIMP3 were less abundant. | Compartment-specific expression of collagens and their processing enzymes in intrapulmonary arteries of IPAH patients.
Hoffmann J, Marsh LM, Pieper M, Stacher E, Ghanim B, Kovacs G, König P, Wilkens H, Haitchi HM, Hoefler G, Klepetko W, Olschewski H, Olschewski A, Kwapiszewska G., Free PMC Article | 08/1/2015 |
| The expression of MMP-19 in the main forms of gastrointestinal diseases, was analysed. | Differential expression and processing of matrix metalloproteinase 19 marks progression of gastrointestinal diseases.
Cervinková M, Horák P, Kanchev I, Matěj R, Fanta J, Sequens R, Kašpárek P, Sarnová L, Turečková J, Sedláček R. | 04/4/2015 |
| Matrix metalloproteinase-19 in lung epithelial cells stimulates proliferation and cell migration. Read More: http://www.atsjournals.org/doi/full/10.1164/rccm.201310-1903OC | Matrix metalloproteinase-19 promotes metastatic behavior in vitro and is associated with increased mortality in non-small cell lung cancer.
Yu G, Herazo-Maya JD, Nukui T, Romkes M, Parwani A, Juan-Guardela BM, Robertson J, Gauldie J, Siegfried JM, Kaminski N, Kass DJ., Free PMC Article | 02/28/2015 |
| ASNS and MMP19, along with eIF3a, are the sensitivity factors for cisplatin treatment and may serve as potential candidate molecular markers for predicting cisplatin sensitivity of advanced nasopharyngeal carcinoma. | Overexpression of asparagine synthetase and matrix metalloproteinase 19 confers cisplatin sensitivity in nasopharyngeal carcinoma cells.
Liu RY, Dong Z, Liu J, Zhou L, Huang W, Khoo SK, Zhang Z, Petillo D, Teh BT, Qian CN, Zhang JT., Free PMC Article | 05/24/2014 |
| These findings indicated for the first time that the co-expression of MMP-14 and MMP-19 is significantly correlated with prognosis in glioma patients | Co-expression of MMP-14 and MMP-19 predicts poor survival in human glioma.
Wang L, Yuan J, Tu Y, Mao X, He S, Fu G, Zong J, Zhang Y. | 07/27/2013 |
| Up-regulation of matrix metalloproteinase-19 (MMP19) induced by lung injury may play a protective role in the development of fibrosis through the induction of prostaglandin-endoperoxide synthase 2 (PTGS2). | Matrix metalloproteinase-19 is a key regulator of lung fibrosis in mice and humans.
Yu G, Kovkarova-Naumovski E, Jara P, Parwani A, Kass D, Ruiz V, Lopez-Otín C, Rosas IO, Gibson KF, Cabrera S, Ramírez R, Yousem SA, Richards TJ, Chensny LJ, Selman M, Kaminski N, Pardo A., Free PMC Article | 12/29/2012 |
| MMP-15 and MMP-19 are upregulated during colorectal tumorigenesis | Matrix metalloproteinases 15 and 19 are stromal regulators of colorectal cancer development from the early stages.
Sena P, Mariani F, Marzona L, Benincasa M, Ponz de Leon M, Palumbo C, Roncucci L. | 09/1/2012 |
| MMP-19 processes human plasminogen in a characteristic cleavage pattern to generate three angiostatin-like fragments | Matrix metalloproteinase-19 inhibits growth of endothelial cells by generating angiostatin-like fragments from plasminogen.
Brauer R, Beck IM, Roderfeld M, Roeb E, Sedlacek R., Free PMC Article | 12/10/2011 |
| vascular MMP-19 expression significantly associated with Cerebral amyloid angiopathy--associated intracerebral haemorrhage | Matrix metalloproteinase-β19 expressed in cerebral amyloid angiopathy.
Tanskanen M, Myllykangas L, Saarialho-Kere U, Paetau A. | 04/30/2011 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators., Free PMC Article | 09/15/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesA genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).
Romero R, Friel LA, Velez Edwards DR, Kusanovic JP, Hassan SS, Mazaki-Tovi S, Vaisbuch E, Kim CJ, Erez O, Chaiworapongsa T, Pearce BD, Bartlett J, Salisbury BA, Anant MK, Vovis GF, Lee MS, Gomez R, Behnke E, Oyarzun E, Tromp G, Williams SM, Menon R. Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.
Romero R, Velez Edwards DR, Kusanovic JP, Hassan SS, Mazaki-Tovi S, Vaisbuch E, Kim CJ, Chaiworapongsa T, Pearce BD, Friel LA, Bartlett J, Anant MK, Salisbury BA, Vovis GF, Lee MS, Gomez R, Behnke E, Oyarzun E, Tromp G, Williams SM, Menon R. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium. | 06/30/2010 |
| the increase of MMP19 expression hallmarks the progression of cutaneous melanoma | MMP19 is upregulated during melanoma progression and increases invasion of melanoma cells.
Müller M, Beck IM, Gadesmann J, Karschuk N, Paschen A, Proksch E, Djonov V, Reiss K, Sedlacek R. | 06/28/2010 |
| Taken together, these results indicate that MMP19 is highly expressed in proliferating astrocytoma/glioma cells, and that its expression may facilitate their invasion through brain extracellular matrix components. | Matrix metalloproteinase-19 is highly expressed in astroglial tumors and promotes invasion of glioma cells.
Lettau I, Hattermann K, Held-Feindt J, Brauer R, Sedlacek R, Mentlein R. | 05/10/2010 |