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    MITF melanocyte inducing transcription factor [ Homo sapiens (human) ]

    Gene ID: 4286, updated on 8-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    MITF regulates the subcellular location of HIF1alpha through SUMOylation to promote the invasion and metastasis of daughter cells derived from polyploid giant cancer cells.

    MITF regulates the subcellular location of HIF1α through SUMOylation to promote the invasion and metastasis of daughter cells derived from polyploid giant cancer cells.
    Zheng M, Tian S, Zhou X, Yan M, Zhou M, Yu Y, Zhang Y, Wang X, Li N, Ren L, Zhang S., Free PMC Article

    03/13/2024
    Emerging roles of MITF as a crucial regulator of immunity.

    Emerging roles of MITF as a crucial regulator of immunity.
    Lee A, Lim J, Lim JS., Free PMC Article

    03/6/2024
    Modeling of pigmentation disorders associated with MITF mutation in Waardenburg syndrome revealed an impaired melanogenesis pathway in iPS-derived melanocytes.

    Modeling of pigmentation disorders associated with MITF mutation in Waardenburg syndrome revealed an impaired melanogenesis pathway in iPS-derived melanocytes.
    Wen J, Song J, Chen J, Feng Z, Jing Q, Gong W, Kang X, Mei L, He C, Ma L, Feng Y.

    01/17/2024
    Ataxia Telangiectasia Mutated Signaling Delays Skin Pigmentation upon UV Exposure by Mediating MITF Function toward DNA Repair Mode.

    Ataxia Telangiectasia Mutated Signaling Delays Skin Pigmentation upon UV Exposure by Mediating MITF Function toward DNA Repair Mode.
    Elkoshi N, Parikh S, Malcov-Brog H, Parikh R, Manich P, Netti F, Maliah A, Elkoshi H, Haj M, Rippin I, Frand J, Perluk T, Haiat-Factor R, Golan T, Regev-Rudzki N, Kiper E, Brenner R, Gonen P, Dror I, Levi H, Hameiri O, Cohen-Gulkar M, Eldar-Finkelman H, Ast G, Nizri E, Ziv Y, Elkon R, Khaled M, Ebenstein Y, Shiloh Y, Levy C.

    11/28/2023
    GREB1 isoform 4 is specifically transcribed by MITF and required for melanoma proliferation.

    GREB1 isoform 4 is specifically transcribed by MITF and required for melanoma proliferation.
    Shinzawa K, Matsumoto S, Sada R, Harada A, Saitoh K, Kato K, Ikeda S, Hirayama A, Yokoi K, Tanemura A, Nimura K, Ikawa M, Soga T, Kikuchi A., Free PMC Article

    11/1/2023
    Acetylation reprograms MITF target selectivity and residence time.

    Acetylation reprograms MITF target selectivity and residence time.
    Louphrasitthiphol P, Loffreda A, Pogenberg V, Picaud S, Schepsky A, Friedrichsen H, Zeng Z, Lashgari A, Thomas B, Patton EE, Wilmanns M, Filippakopoulos P, Lambert JP, Steingrímsson E, Mazza D, Goding CR., Free PMC Article

    10/2/2023
    Integrative analyses of RNA-seq and ChIP-seq Reveal MITF as a Target Gene of TFPI-2 in MDA231 Cells.

    Integrative analyses of RNA-seq and ChIP-seq Reveal MITF as a Target Gene of TFPI-2 in MDA231 Cells.
    Wang G, Zhang G, Zhu N, Zhu C, Kang M, Zuo G, Niu Z, Ye W, Tian B, Cai R.

    09/25/2023
    MITF Downregulation Induces Death in Human Mast Cell Leukemia Cells and Impairs IgE-Dependent Degranulation.

    MITF Downregulation Induces Death in Human Mast Cell Leukemia Cells and Impairs IgE-Dependent Degranulation.
    Proaño-Pérez E, Ollé L, Guo Y, Aparicio C, Guerrero M, Muñoz-Cano R, Martin M., Free PMC Article

    03/16/2023
    The microphthalmia-associated transcription factor is involved in gastrointestinal stromal tumor growth.

    The microphthalmia-associated transcription factor is involved in gastrointestinal stromal tumor growth.
    Proaño-Pérez E, Serrano-Candelas E, García-Valverde A, Rosell J, Gómez-Peregrina D, Navinés-Ferrer A, Guerrero M, Serrano C, Martín M.

    02/22/2023
    MiR-182 Is Upregulated in Prostate Cancer and Contributes to Tumor Progression by Targeting MITF.

    MiR-182 Is Upregulated in Prostate Cancer and Contributes to Tumor Progression by Targeting MITF.
    Stafford MYC, McKenna DJ., Free PMC Article

    02/16/2023
    Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells.

    Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells.
    Lee A, Park H, Lim S, Lim J, Koh J, Jeon YK, Yang Y, Lee MS, Lim JS., Free PMC Article

    01/14/2023
    SMILE Downregulation during Melanogenesis Induces MITF Transcription in B16F10 Cells.

    SMILE Downregulation during Melanogenesis Induces MITF Transcription in B16F10 Cells.
    Truong XT, Lee YS, Nguyen TTP, Kim HJ, Kim SH, Moon C, Kim DK, Choi HS, Jeon TI., Free PMC Article

    12/31/2022
    Identification of nine novel variants across PAX3, SOX10, EDNRB, and MITF genes in Waardenburg syndrome with next-generation sequencing.

    Identification of nine novel variants across PAX3, SOX10, EDNRB, and MITF genes in Waardenburg syndrome with next-generation sequencing.
    Lee CY, Lo MY, Chen YM, Lin PH, Hsu CJ, Chen PL, Wu CC, Hsu JS., Free PMC Article

    12/24/2022
    Study on the Mechanism of miR-125b-5p Affecting Melanocyte Biological Behavior and Melanogenesis in Vitiligo through Regulation of MITF.

    Study on the Mechanism of miR-125b-5p Affecting Melanocyte Biological Behavior and Melanogenesis in Vitiligo through Regulation of MITF.
    Wang X, Wu Y, Du P, Xu L, Chen Y, Li J, Pan X, Wang Z., Free PMC Article

    12/10/2022
    The MITF regulatory network in melanoma.

    The MITF regulatory network in melanoma.
    Chauhan JS, Hölzel M, Lambert JP, Buffa FM, Goding CR., Free PMC Article

    09/3/2022
    MiTF/TFE Translocation Renal Cell Carcinomas: From Clinical Entities to Molecular Insights.

    MiTF/TFE Translocation Renal Cell Carcinomas: From Clinical Entities to Molecular Insights.
    Simonaggio A, Ambrosetti D, Verkarre V, Auvray M, Oudard S, Vano YA., Free PMC Article

    08/6/2022
    A review of neoplasms with MITF/MiT family translocations.

    A review of neoplasms with MITF/MiT family translocations.
    Wei S, Testa JR, Argani P.

    06/25/2022
    Identification of novel MITF mutations in Chinese families with Waardenburg syndrome type II.

    Identification of novel MITF mutations in Chinese families with Waardenburg syndrome type II.
    Wang J, Lu Y, Yan X, Shen T, Li L, Rao Y, Tan B, Xiong W, Cheng J, Zhao Y, Yuan H., Free PMC Article

    03/19/2022
    Intronic variants of MITF (rs7623610) and CREB1 (rs10932201) genes may enhance splicing efficiency in human melanoma cell line.

    Intronic variants of MITF (rs7623610) and CREB1 (rs10932201) genes may enhance splicing efficiency in human melanoma cell line.
    Carron J, Torricelli C, Silva JK, Coser LO, Lima CSP, Lourenço GJ.

    03/5/2022
    Microphthalmia-Associated Transcription Factor in Senescence and Age-Related Diseases.

    Microphthalmia-Associated Transcription Factor in Senescence and Age-Related Diseases.
    Zhang J, Mou Y, Gong H, Chen H, Xiao H.

    03/5/2022
    Genetic Variants and Somatic Alterations Associated with MITF-E318K Germline Mutation in Melanoma Patients.

    Genetic Variants and Somatic Alterations Associated with MITF-E318K Germline Mutation in Melanoma Patients.
    Vergani E, Frigerio S, Dugo M, Devecchi A, Feltrin E, De Cecco L, Vallacchi V, Cossa M, Di Guardo L, Manoukian S, Peissel B, Ferrari A, Gallino G, Maurichi A, Rivoltini L, Sensi M, Rodolfo M., Free PMC Article

    02/19/2022
    Hinokitiol-induced decreases of tyrosinase and microphthalmia-associated transcription factor are mediated by the endoplasmic reticulum-associated degradation pathway in human melanoma cells.

    Hinokitiol-induced decreases of tyrosinase and microphthalmia-associated transcription factor are mediated by the endoplasmic reticulum-associated degradation pathway in human melanoma cells.
    Oyama T, Ogawa H, Shirai Y, Abe H, Kamiya T, Abe T, Tanuma SI.

    02/5/2022
    Circadian clock protein BMAL1 regulates melanogenesis through MITF in melanoma cells.

    Circadian clock protein BMAL1 regulates melanogenesis through MITF in melanoma cells.
    Sarkar S, Porter KI, Dakup PP, Gajula RP, Koritala BSC, Hylton R, Kemp MG, Wakamatsu K, Gaddameedhi S., Free PMC Article

    02/5/2022
    MITF reprograms the extracellular matrix and focal adhesion in melanoma.

    MITF reprograms the extracellular matrix and focal adhesion in melanoma.
    Dilshat R, Fock V, Kenny C, Gerritsen I, Lasseur RMJ, Travnickova J, Eichhoff OM, Cerny P, Möller K, Sigurbjörnsdóttir S, Kirty K, Einarsdottir BÓ, Cheng PF, Levesque M, Cornell RA, Patton EE, Larue L, de Tayrac M, Magnúsdóttir E, Ögmundsdóttir MH, Steingrimsson E., Free PMC Article

    02/5/2022
    NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism.

    NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism.
    Allouche J, Rachmin I, Adhikari K, Pardo LM, Lee JH, McConnell AM, Kato S, Fan S, Kawakami A, Suita Y, Wakamatsu K, Igras V, Zhang J, Navarro PP, Lugo CM, Noonan HR, Christie KA, Itin K, Mujahid N, Lo JA, Won CH, Evans CL, Weng QY, Wang H, Osseiran S, Lovas A, Németh I, Cozzio A, Navarini AA, Hsiao JJ, Nguyen N, Kemény LV, Iliopoulos O, Berking C, Ruzicka T, Gonzalez-José R, Bortolini MC, Canizales-Quinteros S, Acuna-Alonso V, Gallo C, Poletti G, Bedoya G, Rothhammer F, Ito S, Schiaffino MV, Chao LH, Kleinstiver BP, Tishkoff S, Zon LI, Nijsten T, Ruiz-Linares A, Fisher DE, Roider E., Free PMC Article

    01/8/2022
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