| Assessment of MGP gene expression in cancer and contribution to prognosis. | Assessment of MGP gene expression in cancer and contribution to prognosis.
Caiado H, Cancela ML, Conceição N. | 11/13/2023 |
| lncRNA MIR31HG Regulates Proliferation and Migration by Targeting Matrix Gla Protein in Nonsyndromic Cleft Lip With or Without Cleft Palate. | lncRNA MIR31HG Regulates Proliferation and Migration by Targeting Matrix Gla Protein in Nonsyndromic Cleft Lip With or Without Cleft Palate.
Li X, Xu X, Liu L, Tian Y, Gao Y, Zhu G, Lou S, Zhong W, Li D, Pan Y. | 07/19/2023 |
| Reduced APPL1 impairs osteogenic differentiation of mesenchymal stem cells by facilitating MGP expression to disrupt the BMP2 pathway in osteoporosis. | Reduced APPL1 impairs osteogenic differentiation of mesenchymal stem cells by facilitating MGP expression to disrupt the BMP2 pathway in osteoporosis.
Yuan W, Liu W, Zhang Y, Wang X, Xu C, Li Q, Ji P, Wang J, Feng P, Wu Y, Shen H, Wang P., Free PMC Article | 07/7/2023 |
| Matrix Gla Protein drives stemness and tumor initiation in ovarian cancer. | Matrix Gla Protein drives stemness and tumor initiation in ovarian cancer.
Nieddu V, Melocchi V, Battistini C, Franciosa G, Lupia M, Stellato C, Bertalot G, Olsen JV, Colombo N, Bianchi F, Cavallaro U., Free PMC Article | 04/4/2023 |
| 1,25-(OH)2D3 participates and modulates airway remodeling by reducing MGP and TGF-beta1 expression in TNF-alpha-induced airway smooth muscle cells. | 1,25-(OH)2D3 participates and modulates airway remodeling by reducing MGP and TGF-β1 expression in TNF-α-induced airway smooth muscle cells.
Xing YM, Li PS, Liu Y. | 03/5/2022 |
| Matrix Gla Protein Levels Are Associated With Arterial Stiffness and Incident Heart Failure With Preserved Ejection Fraction. | Matrix Gla Protein Levels Are Associated With Arterial Stiffness and Incident Heart Failure With Preserved Ejection Fraction.
Malhotra R, Nicholson CJ, Wang D, Bhambhani V, Paniagua S, Slocum C, Sigurslid HH, Lino Cardenas CL, Li R, Boerboom SL, Chen YC, Hwang SJ, Yao C, Ichinose F, Bloch DB, Lindsay ME, Lewis GD, Aragam JR, Hoffmann U, Mitchell GF, Hamburg NM, Vasan RS, Benjamin EJ, Larson MG, Zapol WM, Cheng S, Roh JD, O'Donnell CJ, Nguyen C, Levy D, Ho JE., Free PMC Article | 02/19/2022 |
| Characterization of dynamic changes in Matrix Gla Protein (MGP) gene expression as function of genetic risk alleles, osteoarthritis relevant stimuli, and the vitamin K inhibitor warfarin. | Characterization of dynamic changes in Matrix Gla Protein (MGP) gene expression as function of genetic risk alleles, osteoarthritis relevant stimuli, and the vitamin K inhibitor warfarin.
Houtman E, Coutinho de Almeida R, Tuerlings M, Suchiman HED, Broekhuis D, Nelissen RGHH, Ramos YFM, van Meurs JBJ, Meulenbelt I. | 01/22/2022 |
| Suppression MGP inhibits tumor proliferation and reverses oxaliplatin resistance in colorectal cancer. | Suppression MGP inhibits tumor proliferation and reverses oxaliplatin resistance in colorectal cancer.
Huang C, Wang M, Wang J, Wu D, Gao Y, Huang K, Yao X. | 09/18/2021 |
| Intracellular matrix Gla protein promotes tumor progression by activating JAK2/STAT5 signaling in gastric cancer. | Intracellular matrix Gla protein promotes tumor progression by activating JAK2/STAT5 signaling in gastric cancer.
Wang M, Chen L, Chen Y, Wei R, Guo Q, Zhu S, Guo S, Zhu S, Zhang S, Min L., Free PMC Article | 05/15/2021 |
| Circulating Levels of Dephosphorylated-Uncarboxylated Matrix Gla Protein in Patients with Acute Coronary Syndrome. | Circulating Levels of Dephosphorylated-Uncarboxylated Matrix Gla Protein in Patients with Acute Coronary Syndrome.
Bilalic A, Ticinovic Kurir T, Kumric M, Borovac JA, Matetic A, Supe-Domic D, Bozic J., Free PMC Article | 04/13/2021 |
| The Association of dp-ucMGP with Cardiovascular Morbidity and Decreased Renal Function in Diabetic Chronic Kidney Disease. | The Association of dp-ucMGP with Cardiovascular Morbidity and Decreased Renal Function in Diabetic Chronic Kidney Disease.
Roumeliotis S, Roumeliotis A, Stamou A, Leivaditis K, Kantartzi K, Panagoutsos S, Liakopoulos V., Free PMC Article | 02/27/2021 |
| Uncarboxylated matrix Gla-protein: A biomarker of vitamin K status and cardiovascular risk. | Uncarboxylated matrix Gla-protein: A biomarker of vitamin K status and cardiovascular risk.
Jespersen T, Møllehave LT, Thuesen BH, Skaaby T, Rossing P, Toft U, Jørgensen NR, Corfixen BL, Jakobsen J, Frimodt-Møller M, Linneberg A. | 02/6/2021 |
| High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam. | High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
Machado-Fragua MD, Hoogendijk EO, Struijk EA, Rodriguez-Artalejo F, Lopez-Garcia E, Beulens JW, van Ballegooijen AJ. | 02/2/2021 |
| Plasma dephosphorylated-uncarboxylated Matrix Gla-Protein (dp-ucMGP): reference intervals in Caucasian adults and diabetic kidney disease biomarker potential. | Plasma dephosphorylated-uncarboxylated Matrix Gla-Protein (dp-ucMGP): reference intervals in Caucasian adults and diabetic kidney disease biomarker potential.
Griffin TP, Islam MN, Wall D, Ferguson J, Griffin DG, Griffin MD, O'Shea PM., Free PMC Article | 11/21/2020 |
| Renal Resistive Index Is Associated With Inactive Matrix Gla (gamma-Carboxyglutamate) Protein in an Adult Population-Based Study. | Renal Resistive Index Is Associated With Inactive Matrix Gla (γ-Carboxyglutamate) Protein in an Adult Population-Based Study.
Jaques DA, Pivin E, Pruijm M, Ackermann D, Guessous I, Ehret G, Wei FF, Staessen JA, Pechère-Bertschi A, Vermeer C, Vogt B, Burnier M, Martin PY, Bochud M, Ponte B., Free PMC Article | 09/19/2020 |
| Matrix Gla protein polymorphism rs1800801 associates with recurrence of ischemic stroke. | Matrix Gla protein polymorphism rs1800801 associates with recurrence of ischemic stroke.
Hendrix P, Sofoluke N, Adams M, Kunaprayoon S, Zand R, Kolinovsky AN, Person TN, Gupta M, Goren O, Kirchner HL, Schirmer CM, Rost NS, Faber JE, Griessenauer CJ., Free PMC Article | 09/5/2020 |
| In people representative for the general population, higher inactive desphospho-uncarboxylated MGP was associated with greater PWV , central pulse pressure, forward pulse wave, and backward pulse wave. | Central Hemodynamics in Relation to Circulating Desphospho-Uncarboxylated Matrix Gla Protein: A Population Study.
Wei FF, Thijs L, Cauwenberghs N, Yang WY, Zhang ZY, Yu CG, Kuznetsova T, Nawrot TS, Struijker-Boudier HAJ, Verhamme P, Vermeer C, Staessen JA., Free PMC Article | 07/11/2020 |
| Inactive matrix gla protein plasma levels are associated with peripheral neuropathy in Type 2 diabetes. | Inactive matrix gla protein plasma levels are associated with peripheral neuropathy in Type 2 diabetes.
Jeannin AC, Salem JE, Massy Z, Aubert CE, Vermeer C, Amouyal C, Phan F, Halbron M, Funck-Brentano C, Hartemann A, Bourron O., Free PMC Article | 06/20/2020 |
| MGP expression is subject to cis-acting regulators that correlate with the OA association signal. These are active in a range of joint tissues but have effects which are particularly strong in cartilage | Expression analysis of the osteoarthritis genetic susceptibility mapping to the matrix Gla protein gene MGP.
Shepherd C, Reese AE, Reynard LN, Loughlin J., Free PMC Article | 05/30/2020 |
| our results showed that the HOXC8-MGP axis played an important role in the tumorigenesis of Triple-negative breast cancer (TNBC) and might be a promising therapeutic target for TNBC treatment | Upregulation of MGP by HOXC8 promotes the proliferation, migration, and EMT processes of triple-negative breast cancer.
Gong C, Zou J, Zhang M, Zhang J, Xu S, Zhu S, Yang M, Li D, Wang Y, Shi J, Li Y. | 02/1/2020 |
| higher plasma dp-ucMGP concentrations found in African American hemodialysis patients may be associated with greater arterial stiffness and endothelial dysfunction. | Inactive Matrix Gla Protein, Arterial Stiffness, and Endothelial Function in African American Hemodialysis Patients.
Fain ME, Kapuku GK, Paulson WD, Williams CF, Raed A, Dong Y, Knapen MHJ, Vermeer C, Pollock NK. | 11/23/2019 |
| Chronic kidney disease is associated with increased (inactive) dp-ucMGP, a vitamin K-dependent inhibitor of vascular calcification, which correlates with large artery stiffness. | Circulating Dephospho-Uncarboxylated Matrix Gla-Protein Is Associated With Kidney Dysfunction and Arterial Stiffness.
Puzantian H, Akers SR, Oldland G, Javaid K, Miller R, Ge Y, Ansari B, Lee J, Suri A, Hasmath Z, Townsend R, Chirinos JA., Free PMC Article | 11/23/2019 |
| Study found that high expression level of MGP is related with a worst prognosis of colorectal cancer (CRC) and correlated with a worse prognosis and survival rate lower than five years. | Evaluation of MGP gene expression in colorectal cancer.
Caiado H, Conceição N, Tiago D, Marreiros A, Vicente S, Enriquez JL, Vaz AM, Antunes A, Guerreiro H, Caldeira P, Cancela ML. | 11/9/2019 |
| this study shows that MGP gene rs1800802 polymorphism is associated with increased risk for knee knee osteoarthritis (OA) in Chinese Han population and the rs1800802 polymorphism may be a diagnostic marker of radiographic knee OA. | Association of matrix Gla protein polymorphism and knee osteoarthritis in a chinese population.
Hui W, Cao Z, Wang X, Zhu J., Free PMC Article | 07/27/2019 |
| The polymorphisms of OPN and MGP were not significantly associated with primary knee osteoarthritis in the codominant, dominant, and recessive models (p > 0.05). The study suggests that there are no associations between OPN and MGP polymorphisms with primary knee osteoarthritis in Mexican population. | Genetic association analysis of Osteopontin and Matrix Gla Protein genes polymorphisms with primary knee osteoarthritis in Mexican population.
Borgonio-Cuadra VM, González-Huerta NC, Rojas-Toledo EX, Morales-Hernández E, Pérez-Hernández N, Rodríguez-Pérez JM, Tovilla-Zárate CA, González-Castro TB, Hernández-Díaz Y, López-Narváez ML, Miranda-Duarte A. | 05/18/2019 |