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    MEOX1 mesenchyme homeobox 1 [ Homo sapiens (human) ]

    Gene ID: 4222, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Unraveling the molecular mechanisms of lymph node metastasis in ovarian cancer: focus on MEOX1.

    Unraveling the molecular mechanisms of lymph node metastasis in ovarian cancer: focus on MEOX1.
    Li J, Sun Y, Zhi X, Sun Y, Abudousalamu Z, Lin Q, Li B, Yao L, Chen M., Free PMC Article

    03/19/2024
    Identification of the novel FOXP3-dependent Treg cell transcription factor MEOX1 by high-dimensional analysis of human CD4[+] T cells.

    Identification of the novel FOXP3-dependent T(reg) cell transcription factor MEOX1 by high-dimensional analysis of human CD4(+) T cells.
    Baßler K, Schmidleithner L, Shakiba MH, Elmzzahi T, Köhne M, Floess S, Scholz R, Ohkura N, Sadlon T, Klee K, Neubauer A, Sakaguchi S, Barry SC, Huehn J, Bonaguro L, Ulas T, Beyer M., Free PMC Article

    08/11/2023
    MEOX1 suppresses the progression of lung cancer cells by inhibiting the cell-cycle checkpoint gene CCNB1.

    MEOX1 suppresses the progression of lung cancer cells by inhibiting the cell-cycle checkpoint gene CCNB1.
    Xiao X, Rui B, Rui H, Ju M, Hongtao L.

    02/5/2022
    A transcriptional switch governs fibroblast activation in heart disease.

    A transcriptional switch governs fibroblast activation in heart disease.
    Alexanian M, Przytycki PF, Micheletti R, Padmanabhan A, Ye L, Travers JG, Gonzalez-Teran B, Silva AC, Duan Q, Ranade SS, Felix F, Linares-Saldana R, Li L, Lee CY, Sadagopan N, Pelonero A, Huang Y, Andreoletti G, Jain R, McKinsey TA, Rosenfeld MG, Gifford CA, Pollard KS, Haldar SM, Srivastava D., Free PMC Article

    01/22/2022
    Characterization of the proteome and metabolome of human liver sinusoidal endothelial-like cells derived from induced pluripotent stem cells.

    Characterization of the proteome and metabolome of human liver sinusoidal endothelial-like cells derived from induced pluripotent stem cells.
    Danoy M, Jellali R, Tauran Y, Bruce J, Leduc M, Gilard F, Gakière B, Scheidecker B, Kido T, Miyajima A, Soncin F, Sakai Y, Leclerc E.

    01/8/2022
    Mesenchyme homeobox 1 mediated-promotion of osteoblastic differentiation is negatively regulated by mir-3064-5p.

    Mesenchyme homeobox 1 mediated-promotion of osteoblastic differentiation is negatively regulated by mir-3064-5p.
    Huang M, Li X, Li G.

    01/8/2022
    Expression quantitative trait loci for ETV4 and MEOX1 are associated with adult asthma in Japanese populations.

    Expression quantitative trait loci for ETV4 and MEOX1 are associated with adult asthma in Japanese populations.
    Yatagai Y, Oshima H, Sakamoto T, Shigemasa R, Kitazawa H, Hyodo K, Masuko H, Iijima H, Naito T, Saito T, Hirota T, Tamari M, Hizawa N., Free PMC Article

    12/18/2021
    Combined p53- and PTEN-deficiency activates expression of mesenchyme homeobox 1 (MEOX1) required for growth of triple-negative breast cancer.

    Combined p53- and PTEN-deficiency activates expression of mesenchyme homeobox 1 (MEOX1) required for growth of triple-negative breast cancer.
    Gasparyan M, Lo MC, Jiang H, Lin CC, Sun D., Free PMC Article

    01/23/2021
    The expression of Meox1 protein in the scar tissue was significantly higher than that in normal skin of patients with hypertrophic scars.

    [Mechanism of transcriptional regulation of Meox1 by transforming growth factor β (1) and its effect on cell migration of adult human dermal fibroblasts].
    Wei ZY, Li HS, Zhou JY, Han C, Dong H, Wu YZ, He WF, Tian Y, Luo GX.

    05/16/2020
    high levels of MEOX1 especially nuclear staining was an independent prognostic factor for non-small-cell lung cancer

    MEOX1 Promotes Tumor Progression and Predicts Poor Prognosis in Human Non-Small-Cell Lung Cancer.
    Sun L, Yuan H, Burnett J, Gasparyan M, Zhang Y, Zhang F, Yang Z, Ran Y, Sun D., Free PMC Article

    04/27/2019
    MEOX1 is a clinically relevant novel target in BCSCs and mesenchymal-like cancer cells in PTEN-deficient trastuzumab resistant breast cancer and may serve as target for future drug development.

    Novel cancer stem cell targets during epithelial to mesenchymal transition in PTEN-deficient trastuzumab-resistant breast cancer.
    Sun L, Burnett J, Gasparyan M, Xu F, Jiang H, Lin CC, Myers I, Korkaya H, Liu Y, Connarn J, He H, Zhang N, Wicha MS, Sun D., Free PMC Article

    02/10/2018
    The G > A p.Q84X mutation in the MEOX1 is identified in Klippel-Feil syndrome.

    Mutation in MEOX1 gene causes a recessive Klippel-Feil syndrome subtype.
    Bayrakli F, Guclu B, Yakicier C, Balaban H, Kartal U, Erguner B, Sagiroglu MS, Yuksel S, Ozturk AR, Kazanci B, Ozum U, Kars HZ., Free PMC Article

    06/21/2014
    We describe a multiplex consanguineous family in which isolated KFS maps to a single 17q21.31 locus that harbors a homozygous frameshift deletion in MEOX1; this deletion results in complete instability of the transcript

    Mutations in MEOX1, encoding mesenchyme homeobox 1, cause Klippel-Feil anomaly.
    Mohamed JY, Faqeih E, Alsiddiky A, Alshammari MJ, Ibrahim NA, Alkuraya FS., Free PMC Article

    03/16/2013
    The results demonstrate that MEOX1 is a critical target gene and cofactor of PBX1 in ovarian cancers.

    Identification of PBX1 target genes in cancer cells by global mapping of PBX1 binding sites.
    Thiaville MM, Stoeck A, Chen L, Wu RC, Magnani L, Oidtman J, Shih IeM, Lupien M, Wang TL., Free PMC Article

    09/22/2012
    No mutations were identified in the PAX1 and MEOX1 exons or flanking intronic sequences, excluding them as likely causative genes for diaphanospondylodysostosis

    Diaphanospondylodysostosis: six new cases and exclusion of the candidate genes, PAX1 and MEOX1.
    Vatanavicharn N, Graham JM Jr, Curry CJ, Pepkowitz S, Lachman RS, Rimoin DL, Wilcox WR.

    01/21/2010
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