| Long-Read MDM4 Sequencing Reveals Aberrant Isoform Landscape in Metastatic Melanomas. | Long-Read MDM4 Sequencing Reveals Aberrant Isoform Landscape in Metastatic Melanomas.
Patrick N, Markey M., Free PMC Article | 10/15/2024 |
| miR-34c-5p inhibited fibroblast proliferation, differentiation and epithelial-mesenchymal transition in benign airway stenosis via MDMX/p53 pathway. | miR-34c-5p inhibited fibroblast proliferation, differentiation and epithelial-mesenchymal transition in benign airway stenosis via MDMX/p53 pathway.
Wei J, Chen Y, Feng T, Wei Y, Yang C, Zhang C, Li W, Liu G., Free PMC Article | 03/4/2024 |
| MDM4 was associated with poor prognosis and tumor-immune infiltration of cancers. | MDM4 was associated with poor prognosis and tumor-immune infiltration of cancers.
Liu J, Yang J, Pan Q, Wang X, Wang X, Chen H, Zheng X, Huang Q., Free PMC Article | 02/6/2024 |
| LINC01094 accelerates the metastasis of hepatocellular carcinoma via the miR-26b-3p/MDM4 axis. | LINC01094 accelerates the metastasis of hepatocellular carcinoma via the miR-26b-3p/MDM4 axis.
Mao Y, Hu Z, Zeng Y, Zhou Y, Shi Z. | 08/25/2023 |
| Reduced murine double minute 2 and 4 protein, but not messenger RNA, expression is associated with more severe disease in myelodysplastic syndromes and acute myeloblastic leukaemia. | Reduced murine double minute 2 and 4 protein, but not messenger RNA, expression is associated with more severe disease in myelodysplastic syndromes and acute myeloblastic leukaemia.
Salomao N, Maslah N, Giulianelli A, Drevon L, Aguinaga L, Gu X, Cassinat B, Giraudier S, Fenaux P, Fahraeus R. | 08/11/2023 |
| Murine double minute X plays a central role in leukemic transformation and may be a promising target for leukemia prevention strategies. | Murine double minute X plays a central role in leukemic transformation and may be a promising target for leukemia prevention strategies.
Ueda K. | 06/7/2023 |
| MicroRNA miR-34a-5p inhibition restrains oxidative stress injury of macrophages by targeting MDM4. | MicroRNA miR-34a-5p inhibition restrains oxidative stress injury of macrophages by targeting MDM4.
Kong J, Liu L, Song L, Zhao R, Feng Y. | 06/1/2023 |
| MDM4 polymorphisms associated with the risk but not the prognosis of esophageal cancer in Cixian high-incidence region from northern China. | MDM4 polymorphisms associated with the risk but not the prognosis of esophageal cancer in Cixian high-incidence region from northern China.
Zhou R, Li Y, Wang N, Niu C, Huang X, Cao S, Huo X. | 10/1/2022 |
| (1)H, (15)N and (13)C backbone resonance assignments of the acidic domain of the human MDMX protein. | (1)H, (15)N and (13)C backbone resonance assignments of the acidic domain of the human MDMX protein.
Song Q, Liu XQ, Rainey JK. | 05/14/2022 |
| CPSF4 promotes triple negative breast cancer metastasis by upregulating MDM4. | CPSF4 promotes triple negative breast cancer metastasis by upregulating MDM4.
Lee K, Zheng Q, Lu Q, Xu F, Qin G, Zhai Q, Hong R, Chen M, Deng W, Wang S., Free PMC Article | 03/26/2022 |
| Intimal sarcomas and undifferentiated cardiac sarcomas carry mutually exclusive MDM2, MDM4, and CDK6 amplifications and share a common DNA methylation signature. | Intimal sarcomas and undifferentiated cardiac sarcomas carry mutually exclusive MDM2, MDM4, and CDK6 amplifications and share a common DNA methylation signature.
Koelsche C, Benhamida JK, Kommoss FKF, Stichel D, Jones DTW, Pfister SM, Heilig CE, Fröhling S, Stenzinger A, Buslei R, Mentzel T, Baumhoer D, Ladanyi M, Antonescu CR, Flucke U, Gorp JV, Bode-Lesniewska B, Deimling AV, Mechtersheimer G., Free PMC Article | 03/19/2022 |
| Circular RNA CCDC66 Improves Murine Double Minute 4 (MDM4) Expression through Targeting miR-370 in Colorectal Cancer. | Circular RNA CCDC66 Improves Murine Double Minute 4 (MDM4) Expression through Targeting miR-370 in Colorectal Cancer.
Mo Y, Lu Q, Zhang Q, Chen J, Deng Y, Zhang K, Tao R, Liu W, Wang Y., Free PMC Article | 03/5/2022 |
| MDM2, MDMX, and p73 regulate cell-cycle progression in the absence of wild-type p53. | MDM2, MDMX, and p73 regulate cell-cycle progression in the absence of wild-type p53.
Klein AM, Biderman L, Tong D, Alaghebandan B, Plumber SA, Mueller HS, van Vlimmeren A, Katz C, Prives C., Free PMC Article | 12/25/2021 |
| The ion channel TRPM7 regulates zinc-depletion-induced MDMX degradation. | The ion channel TRPM7 regulates zinc-depletion-induced MDMX degradation.
Wang H, Li B, Asha K, Pangilinan RL, Thuraisamy A, Chopra H, Rokudai S, Yu Y, Prives CL, Zhu Y., Free PMC Article | 12/18/2021 |
| MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism. | MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism.
Ueda K, Kumari R, Schwenger E, Wheat JC, Bohorquez O, Narayanagari SR, Taylor SJ, Carvajal LA, Pradhan K, Bartholdy B, Todorova TI, Goto H, Sun D, Chen J, Shan J, Song Y, Montagna C, Xiong S, Lozano G, Pellagatti A, Boultwood J, Verma A, Steidl U., Free PMC Article | 11/22/2021 |
| Studying Homo-oligomerization and Hetero-oligomerization of MDMX and MDM2 Proteins in Single Living Cells by Using In Situ Fluorescence Correlation Spectroscopy. | Studying Homo-oligomerization and Hetero-oligomerization of MDMX and MDM2 Proteins in Single Living Cells by Using In Situ Fluorescence Correlation Spectroscopy.
Li F, Yu S, Huang X, Dong C, Ren J. | 11/13/2021 |
| The role of miRNAs in MDMX-p53 interplay. | The role of miRNAs in MDMX-p53 interplay.
Yu D, Xu Z, Cheng X, Qin J. | 11/6/2021 |
| Inhibition of the mTOR pathway and reprogramming of protein synthesis by MDM4 reduce ovarian cancer metastatic properties. | Inhibition of the mTOR pathway and reprogramming of protein synthesis by MDM4 reduce ovarian cancer metastatic properties.
Lucà R, Assenza MR, Maiullari F, Pieroni L, Maiullari S, Federici G, Marini F, Rizzi R, Urbani A, Soddu S, Moretti F., Free PMC Article | 10/9/2021 |
| PRPF19 regulates p53-dependent cellular senescence by modulating alternative splicing of MDM4 mRNA. | PRPF19 regulates p53-dependent cellular senescence by modulating alternative splicing of MDM4 mRNA.
Yano K, Takahashi RU, Shiotani B, Abe J, Shidooka T, Sudo Y, Yamamoto Y, Kan S, Sakagami H, Tahara H., Free PMC Article | 08/28/2021 |
| MDMX/MDM4 is highly expressed and contributes to cell growth and survival in anaplastic large cell lymphoma. | MDMX/MDM4 is highly expressed and contributes to cell growth and survival in anaplastic large cell lymphoma.
Sinatkas V, Stathopoulou K, Xagoraris I, Ye J, Vyrla D, Atsaves V, Leventaki V, Medeiros LJ, Rassidakis GZ, Drakos E. | 07/24/2021 |
| MDM4 is targeted by miR-449b-5p to promote the proliferation of endometrial carcinoma. | MDM4 is targeted by miR-449b-5p to promote the proliferation of endometrial carcinoma.
Zhao J, Dong X, Tao SJ, Liu XL, Li Z, Liu JM, Chen Y. | 07/3/2021 |
| Polymorphisms in the TP53-MDM2-MDM4-axis in patients with rheumatoid arthritis. | Polymorphisms in the TP53-MDM2-MDM4-axis in patients with rheumatoid arthritis.
Gansmo LB, Lie BA, Mæhlen MT, Vatten L, Romundstad P, Hveem K, Lønning PE, Knappskog S. | 06/26/2021 |
| Association of KLK3, VAMP8 and MDM4 Genetic Variants within microRNA Binding Sites with Prostate Cancer: Evidence from Serbian Population. | Association of KLK3, VAMP8 and MDM4 Genetic Variants within microRNA Binding Sites with Prostate Cancer: Evidence from Serbian Population.
Kotarac N, Dobrijevic Z, Matijasevic S, Savic-Pavicevic D, Brajuskovic G. | 06/26/2021 |
| MDMX Recruits UbcH5c to Facilitate MDM2 E3 Ligase Activity and Subsequent p53 Degradation In Vivo. | MDMX Recruits UbcH5c to Facilitate MDM2 E3 Ligase Activity and Subsequent p53 Degradation In Vivo.
Yang J, Jin A, Han J, Chen X, Zheng J, Zhang Y., Free PMC Article | 05/15/2021 |
| CDK9 activity is critical for maintaining MDM4 overexpression in tumor cells. | CDK9 activity is critical for maintaining MDM4 overexpression in tumor cells.
Štětková M, Growková K, Fojtík P, Valčíková B, Palušová V, Verlande A, Jorda R, Kryštof V, Hejret V, Alexiou P, Rotrekl V, Uldrijan S., Free PMC Article | 04/24/2021 |