| Molecular Basis of MC1R Activation: Mutation-Induced Alterations in Structural Dynamics. | Molecular Basis of MC1R Activation: Mutation-Induced Alterations in Structural Dynamics.
Cavatão FG, Pinto ÉSM, Krause MJ, Alho CS, Dorn M. | 10/23/2024 |
| Melanoma-associated melanocortin 1 receptor variants confer redox signaling-dependent protection against oxidative DNA damage. | Melanoma-associated melanocortin 1 receptor variants confer redox signaling-dependent protection against oxidative DNA damage.
Castejón-Griñán M, Cerdido S, Sánchez-Beltrán J, Lambertos A, Abrisqueta M, Herraiz C, Jiménez-Cervantes C, García-Borrón JC., Free PMC Article | 05/29/2024 |
| A Side-by-Side Comparison of Wildtype and Variant Melanocortin 1 Receptor Signaling with Emphasis on Protection against Oxidative Damage to DNA. | A Side-by-Side Comparison of Wildtype and Variant Melanocortin 1 Receptor Signaling with Emphasis on Protection against Oxidative Damage to DNA.
Cerdido S, Sánchez-Beltrán J, Lambertos A, Abrisqueta M, Padilla L, Herraiz C, Olivares C, Jiménez-Cervantes C, García-Borrón JC., Free PMC Article | 10/5/2023 |
| Activation of melanocortin-1 receptor signaling in melanoma cells impairs T cell infiltration to dampen antitumor immunity. | Activation of melanocortin-1 receptor signaling in melanoma cells impairs T cell infiltration to dampen antitumor immunity.
Cui Y, Miao Y, Cao L, Guo L, Cui Y, Yan C, Zeng Z, Xu M, Han T., Free PMC Article | 09/23/2023 |
| Alpha-melanocyte stimulating hormone (alpha-MSH): biology, clinical relevance and implication in melanoma. | Alpha-melanocyte stimulating hormone (α-MSH): biology, clinical relevance and implication in melanoma.
Dall'Olmo L, Papa N, Surdo NC, Marigo I, Mocellin S., Free PMC Article | 08/30/2023 |
| Melanocortin 1 Receptor (MC1R): Pharmacological and Therapeutic Aspects. | Melanocortin 1 Receptor (MC1R): Pharmacological and Therapeutic Aspects.
Mun Y, Kim W, Shin D., Free PMC Article | 08/19/2023 |
| The MC1R r allele does not increase melanoma risk in MITF E318K carriers. | The MC1R r allele does not increase melanoma risk in MITF E318K carriers.
Wallingford CK, Demeshko A, Krishnakripa AK, Smit DJ, Duffy DL, Betz-Stablein B, Pflugfelder A, Jagirdar K, Holland E, Mann GJ, Primiero CA, Yanes T, Malvehy J, Badenas C, Carrera C, Aguilera P, Olsen CM, Ward SV, Haass NK, Sturm RA, Puig S, Whiteman DC, Law MH, Cust AE, Potrony M, Soyer HP, McInerney-Leo AM., Free PMC Article | 05/28/2023 |
| Melanocortin 1 receptor variants and their association with phenotypic characteristics and sporadic multiple primary melanomas in a cohort of 402 Spanish subjects. | Melanocortin 1 receptor variants and their association with phenotypic characteristics and sporadic multiple primary melanomas in a cohort of 402 Spanish subjects.
Vírseda-González D, Lázaro-Ochaita P, Ribas Despuig G, Avilés-Izquierdo JA. | 05/5/2023 |
| AMPK Phosphorylates ZDHHC13 to Increase MC1R Activity and Suppress Melanomagenesis. | AMPK Phosphorylates ZDHHC13 to Increase MC1R Activity and Suppress Melanomagenesis.
Sun Y, Li X, Yin C, Zhang J, Liang E, Wu X, Ni Y, Arbesman J, Goding CR, Chen S., Free PMC Article | 04/14/2023 |
| Common genetic variants associated with melanoma risk or naevus count in patients with wildtype MC1R melanoma. | Common genetic variants associated with melanoma risk or naevus count in patients with wildtype MC1R melanoma.
Calbet-Llopart N, Combalia M, Kiroglu A, Potrony M, Tell-Martí G, Combalia A, Brugues A, Podlipnik S, Carrera C, Puig S, Malvehy J, Puig-Butillé JA., Free PMC Article | 01/28/2023 |
| MC1R diversity and its role in skin pigmentation variation in West Maharashtra, India. | MC1R diversity and its role in skin pigmentation variation in West Maharashtra, India.
Jonnalagadda M, Bharti N, Kasibhatla SM, Wagh MA, Joshi R, Ozarkar S, Ashma R. | 07/16/2022 |
| Assessment of melanoma precision prevention materials incorporating MC1R genetic risk information. | Assessment of melanoma precision prevention materials incorporating MC1R genetic risk information.
Lacson JCA, Forgas SM, Doyle SH, Qian L, Del Rio J, Valavanis S, Carvajal R, Gonzalez-Calderon G, Kim Y, Roetzheim RG, Vadaparampil ST, Kanetsky PA., Free PMC Article | 06/11/2022 |
| Genetic diversity of the melanocortin-1 receptor in an admixed population of Rio de Janeiro: Structural and functional impacts of Cys35Tyr variant. | Genetic diversity of the melanocortin-1 receptor in an admixed population of Rio de Janeiro: Structural and functional impacts of Cys35Tyr variant.
Neitzke-Montinelli V, da Silva Figueiredo Celestino Gomes P, Pascutti PG, Moura-Neto RS, Silva R., Free PMC Article | 05/7/2022 |
| MC1R Is a Prognostic Marker and Its Expression Is Correlated with MSI in Colorectal Cancer. | MC1R Is a Prognostic Marker and Its Expression Is Correlated with MSI in Colorectal Cancer.
Peng L, Chang J, Liu X, Lu S, Ren H, Zhou X, Liu Z, Hu P., Free PMC Article | 02/19/2022 |
| Functional characterization of a C-terminal splice variant of the human melanocortin 1 receptor. | Functional characterization of a C-terminal splice variant of the human melanocortin 1 receptor.
Martínez-Vicente I, Abrisqueta M, Herraiz C, Jiménez-Cervantes C, García-Borrón JC, Olivares C. | 02/19/2022 |
| Structural mechanism of calcium-mediated hormone recognition and Gbeta interaction by the human melanocortin-1 receptor. | Structural mechanism of calcium-mediated hormone recognition and Gβ interaction by the human melanocortin-1 receptor.
Ma S, Chen Y, Dai A, Yin W, Guo J, Yang D, Zhou F, Jiang Y, Wang MW, Xu HE., Free PMC Article | 01/29/2022 |
| Melanoma in children and adolescents: analysis of susceptibility genes in 123 Italian patients. | Melanoma in children and adolescents: analysis of susceptibility genes in 123 Italian patients.
Pellegrini C, Raimondi S, Di Nardo L, Ghiorzo P, Menin C, Manganoni MA, Palmieri G, Guida G, Quaglino P, Stanganelli I, Massi D, Pastorino L, Elefanti L, Tosti G, Queirolo P, Leva A, Maurichi A, Rodolfo M, Fargnoli MC, Italian Melanoma Intergroup (IMI). | 01/22/2022 |
| Influence of germline genetic variants on dermoscopic features of melanoma. | Influence of germline genetic variants on dermoscopic features of melanoma.
Pozzobon FC, Tell-Marti G, Calbet-Llopart N, Barreiro A, Espinosa N, Potrony M, Alejo B, Podlipnik S, Combalia M, Puig-Butillé JA, Carrera C, Malvehy J, Puig S. | 01/15/2022 |
| MC1R variants and cutaneous melanoma risk according to histological type, body site, and Breslow thickness: a pooled analysis from the M-SKIP project. | MC1R variants and cutaneous melanoma risk according to histological type, body site, and Breslow thickness: a pooled analysis from the M-SKIP project.
Caini S, Gandini S, Botta F, Tagliabue E, Raimondi S, Nagore E, Zanna I, Maisonneuve P, Newton-Bishop J, Polsky D, Lazovich D, Kumar R, Kanetsky PA, Hoiom V, Ghiorzo P, Landi MT, Ribas G, Menin C, Stratigos AJ, Palmieri G, Guida G, García-Borrón JC, Nan H, Little J, Sera F, Puig S, Fargnoli MC, M-SKIP study group., Free PMC Article | 07/31/2021 |
| The role of MC1R gene variants and phenotypical features in predicting high nevus count. | The role of MC1R gene variants and phenotypical features in predicting high nevus count.
van der Poel LAJ, Bergman W, Gruis NA, Kukutsch NA. | 07/31/2021 |
| MC1R variants in relation to naevi in melanoma cases and controls: a pooled analysis from the M-SKIP project. | MC1R variants in relation to naevi in melanoma cases and controls: a pooled analysis from the M-SKIP project.
Stefanaki I, Stratigos AJ, Kypreou KP, Evangelou E, Gandini S, Maisonneuve P, Polsky D, Lazovich D, Newton-Bishop J, Kanetsky PA, Puig S, Gruis NA, Ghiorzo P, Pellegrini C, De Nicolo A, Ribas G, Guida G, Garcia-Borron JC, Fargnoli MC, Nan H, Landi MT, Little J, Sera F, Raimondi S, M-SKIP Study Group., Free PMC Article | 07/10/2021 |
| Detangling red hair from pain: phenotype-specific contributions from different genetic variants in melanocortin-1 receptor. | Detangling red hair from pain: phenotype-specific contributions from different genetic variants in melanocortin-1 receptor.
Zorina-Lichtenwalter K, Maixner W, Diatchenko L., Free PMC Article | 06/26/2021 |
| The interplay of sun damage and genetic risk in Australian multiple and single primary melanoma cases and controls. | The interplay of sun damage and genetic risk in Australian multiple and single primary melanoma cases and controls.
McMeniman EK, Duffy DL, Jagirdar K, Lee KJ, Peach E, McInerney-Leo AM, De'Ambrosis B, Rayner JE, Smithers BM, Soyer HP, Sturm RA. | 06/19/2021 |
| Melanocortin-1 receptor (MC1R) genotypes do not correlate with size in two cohorts of medium-to-giant congenital melanocytic nevi. | Melanocortin-1 receptor (MC1R) genotypes do not correlate with size in two cohorts of medium-to-giant congenital melanocytic nevi.
Calbet-Llopart N, Pascini-Garrigos M, Tell-Martí G, Potrony M, Martins da Silva V, Barreiro A, Puig S, Captier G, James I, Degardin N, Carrera C, Malvehy J, Etchevers HC, Puig-Butillé JA. | 06/12/2021 |
| Atrophic and hypertrophic skin photoaging and melanocortin-1 receptor (MC1R): the missing link. | Atrophic and hypertrophic skin photoaging and melanocortin-1 receptor (MC1R): the missing link.
Guida S, Ciardo S, De Pace B, De Carvalho N, Farnetani F, Pezzini C, Chester J, Shaniko K, Manganelli M, Guida G, Pellacani G. | 05/29/2021 |