| Myeloid-Mas Signaling Modulates Pathogenic Crosstalk among MYC[+]CD63[+] Endothelial Cells, MMP12[+] Macrophages, and Monocytes in Acetaminophen-Induced Liver Injury. | Myeloid-Mas Signaling Modulates Pathogenic Crosstalk among MYC(+)CD63(+) Endothelial Cells, MMP12(+) Macrophages, and Monocytes in Acetaminophen-Induced Liver Injury.
Chen S, Lu Z, Zhao Y, Xia L, Liu C, Zuo S, Jin M, Jia H, Li S, Zhang S, Yang B, Wang Z, Li J, Wang F, Yang C., Free PMC Article | 05/6/2024 |
| Regulation of vascular angiotensin II type 1 and type 2 receptor and angiotensin-(1-7)/MasR signaling in normal and hypertensive pregnancy. | Regulation of vascular angiotensin II type 1 and type 2 receptor and angiotensin-(1-7)/MasR signaling in normal and hypertensive pregnancy.
Clark CR, Khalil RA., | 02/1/2024 |
| Mas receptor endocytosis and signaling in health and disease. | Mas receptor endocytosis and signaling in health and disease.
Rukavina Mikusic NL, Gironacci MM. | 02/10/2023 |
| Sex Difference in MasR Expression and Functions in the Renal System. | Sex Difference in MasR Expression and Functions in the Renal System.
Choopani S, Nematbakhsh M., Free PMC Article | 10/1/2022 |
| The function of the ACE2/Ang(1-7)/Mas receptor axis of the renin-angiotensin system in myocardial ischemia reperfusion injury. | The function of the ACE2/Ang(1-7)/Mas receptor axis of the renin-angiotensin system in myocardial ischemia reperfusion injury.
Xie JX, Hu J, Cheng J, Liu C, Wei X. | 07/9/2022 |
| Human placenta mesenchymal stem cell protection in ischemic stroke is angiotensin converting enzyme-2 and masR receptor-dependent. | Human placenta mesenchymal stem cell protection in ischemic stroke is angiotensin converting enzyme-2 and masR receptor-dependent.
Barzegar M, Vital S, Stokes KY, Wang Y, Yun JW, White LA, Chernyshev O, Kelley RE, Alexander JS., Free PMC Article | 05/7/2022 |
| Neuroinflammation and COVID-19 Ischemic Stroke Recovery-Evolving Evidence for the Mediating Roles of the ACE2/Angiotensin-(1-7)/Mas Receptor Axis and NLRP3 Inflammasome. | Neuroinflammation and COVID-19 Ischemic Stroke Recovery-Evolving Evidence for the Mediating Roles of the ACE2/Angiotensin-(1-7)/Mas Receptor Axis and NLRP3 Inflammasome.
Che Mohd Nassir CMN, Zolkefley MKI, Ramli MD, Norman HH, Abdul Hamid H, Mustapha M., Free PMC Article | 04/2/2022 |
| Impact of angiotensin II type 1 and G-protein-coupled Mas receptor expression on the pulmonary performance of patients with idiopathic pulmonary fibrosis. | Impact of angiotensin II type 1 and G-protein-coupled Mas receptor expression on the pulmonary performance of patients with idiopathic pulmonary fibrosis.
Raupp D, Fernandes RS, Antunes KH, Perin FA, Rigatto K., Free PMC Article | 07/31/2021 |
| Localization of angiotensin-(1-7) and Mas receptor in the rat ovary throughout the estrous cycle. | Localization of angiotensin-(1-7) and Mas receptor in the rat ovary throughout the estrous cycle.
Pereira VM, Reis FM, Cassali GD, Santos SHS, Casalechi M, Santos RAS, Reis AM. | 07/10/2021 |
| Angiotensin- and angiotensin-(1-7) imbalance affects comorbidity of depression and coronary heart disease. | Angiotensin-Ⅱ and angiotensin-(1-7) imbalance affects comorbidity of depression and coronary heart disease.
Han W, Wei Z, Dang R, Guo Y, Zhang H, Geng C, Wang C, Feng Q, Jiang P. | 07/3/2021 |
| ACE2/Ang-(1-7)/Mas1 axis and the vascular system: vasoprotection to COVID-19-associated vascular disease. | ACE2/Ang-(1-7)/Mas1 axis and the vascular system: vasoprotection to COVID-19-associated vascular disease.
Kuriakose J, Montezano AC, Touyz RM., Free PMC Article | 02/6/2021 |
| Oestrogen-mediated upregulation of the Mas receptor contributes to sex differences in acute lung injury and lung vascular barrier regulation. | Oestrogen-mediated upregulation of the Mas receptor contributes to sex differences in acute lung injury and lung vascular barrier regulation.
Erfinanda L, Ravindran K, Kohse F, Gallo K, Preissner R, Walther T, Kuebler WM. | 02/2/2021 |
| Ang-(1-7) stimulates beige markers and thermogenesis via the Mas receptor. | Angiotensin-(1-7) induces beige fat thermogenesis through the Mas receptor.
Vargas-Castillo A, Tobon-Cornejo S, Del Valle-Mondragon L, Torre-Villalvazo I, Schcolnik-Cabrera A, Guevara-Cruz M, Pichardo-Ontiveros E, Fuentes-Romero R, Bader M, Alenina N, Vidal-Puig A, Hong E, Torres N, Tovar AR. | 05/2/2020 |
| The production of ANG 1-7 was significantly lower in breast cancer cells, whereas the expression of MAS receptor was higher than that in the control breast tissue cells. This finding suggests that substances with MAS receptor agonist activity could be useful in the treatment of breast cancer. | Angiotensin 1-7 formation in breast tissue is attenuated in breast cancer - a study on the metabolism of angiotensinogen in breast cancer cell lines.
Bujak-Gizycka B, Madej J, Bystrowska B, Toton-Zuranska J, Kus K, Kolton-Wroz M, Jawien J, Olszanecki R. | 04/11/2020 |
| We have hypothesized the mechanism that reverses the downregulation of the ACE2-angiotensin 1-7/Mas receptor axis path and the upregulation of angiotensin receptor type 1-mediated signaling. Thus, we posit that ACE2, Ang-(1-7), and the Mas receptor could be novel therapeutic targets for treating benign prostatic hyperplasia . | Embarking Effect of ACE2-Angiotensin 1-7/Mas Receptor Axis in Benign Prostate Hyperplasia.
Singh Y, Gupta G, Sharma R, Matta Y, Mishra A, Pinto TJA, Dua K. | 08/3/2019 |
| MAS1 expression in the left atrium in mitral regurgitation patients significantly differed from those in aortic valve disease patients and normal controls. | Differential Gene Expression Profile of Renin-Angiotensin System in the Left Atrium in Mitral Regurgitation Patients.
Liu WH, Fang YN, Wu CC, Chen MC, Chang JP, Lin YS, Pan KL, Ho WC, Chang TH, Huang YK, Fang CY, Chen CJ, Lee WC., Free PMC Article | 04/13/2019 |
| High MAS1 expression in the endometrium might promote the initiation of endometriosis via migration of proliferative tissue. | The Expression of MAS1, an Angiotensin (1-7) Receptor, in the Eutopic Proliferative Endometria of Endometriosis Patients.
Nakajima T, Chishima F, Nakao T, Hayashi C, Kasuga A, Shinya K, Nakayama T, Azuma H, Ichikawa G, Komatsu A, Yamamoto T, Kawana K. | 01/12/2019 |
| These findings suggest a critical role for MasR in cardiomyocyte survival. | Short-term hypoxia upregulated Mas receptor expression to repress the AT(1) R signaling pathway and attenuate Ang II-induced cardiomyocyte apoptosis.
Chang RL, Chang CF, Ju DT, Ho TJ, Chang TT, Lin JW, Li JC, Cheng SM, Day CH, Viswanadha VP, Huang CY. | 10/13/2018 |
| ANG-(1-7) acts on the receptor MAS to influence a range of mechanisms in the heart, kidney, brain, and other tissues. [review] | The ACE2/Angiotensin-(1-7)/MAS Axis of the Renin-Angiotensin System: Focus on Angiotensin-(1-7).
Santos RAS, Sampaio WO, Alzamora AC, Motta-Santos D, Alenina N, Bader M, Campagnole-Santos MJ., Free PMC Article | 10/6/2018 |
| These findings suggest that mitochondrial assembly receptor signaling may be a promising novel target for oral tongue squamous cell carcinoma. | Mitochondrial assembly receptor expression is an independent prognosticator for patients with oral tongue squamous cell carcinoma.
Su YY, Chen CH, Chien CY, Lin WC, Huang WT, Li SH., Free PMC Article | 07/7/2018 |
| High levels of MAS is associated with angiogenesis in bladder cancer. | Angiotensin II type 2 receptor promotes apoptosis and inhibits angiogenesis in bladder cancer.
Pei N, Mao Y, Wan P, Chen X, Li A, Chen H, Li J, Wan R, Zhang Y, Du H, Chen B, Jiang G, Xia M, Sumners C, Hu G, Gu D, Li H., Free PMC Article | 03/31/2018 |
| Here, we review the role and effects of ACE2, ACE2 activators, Ang-(1-7) and synthetic Mas receptor agonists in the control of inflammation and fibrosis in cardiovascular and renal diseases and as counter-regulators of the ACE-Ang II-AT1 axis. | ACE inhibition, ACE2 and angiotensin-(1-7) axis in kidney and cardiac inflammation and fibrosis.
Simões E Silva AC, Teixeira MM. | 04/1/2017 |
| Downregulation of ACE2/Ang-(1-7)/Mas axis stimulates breast cancer metastasis through the activation of store-operated calcium entry and PAK1/NF-kappaB/Snail1 pathways. | Downregulation of ACE2/Ang-(1-7)/Mas axis promotes breast cancer metastasis by enhancing store-operated calcium entry.
Yu C, Tang W, Wang Y, Shen Q, Wang B, Cai C, Meng X, Zou F. | 02/18/2017 |
| These results indicated that angiotensin-(1-7)/ACE2/Mas axis may reduce liver lipid accumulation partly by regulating lipid-metabolizing genes through ATP/P2 receptor/CaM signaling pathway. | Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis activates Akt signaling to ameliorate hepatic steatosis.
Cao X, Yang F, Shi T, Yuan M, Xin Z, Xie R, Li S, Li H, Yang JK., Free PMC Article | 01/14/2017 |
| Ang-(1-7) downregulated AT1R mRNA, upregulated mRNA levels of Ang II type 2 receptor (AT2R) and Mas receptor (MasR) and p38-MAPK phosphorylation and suppressed H22 cell-endothelial cell communication | Angiotensin-(1-7) Suppresses Hepatocellular Carcinoma Growth and Angiogenesis via Complex Interactions of Angiotensin II Type 1 Receptor, Angiotensin II Type 2 Receptor and Mas Receptor.
Liu Y, Li B, Wang X, Li G, Shang R, Yang J, Wang J, Zhang M, Chen Y, Zhang Y, Zhang C, Hao P., Free PMC Article | 06/11/2016 |