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    MIR215 microRNA 215 [ Homo sapiens (human) ]

    Gene ID: 406997, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    KNOCKDOWN OF CIRC_0114428 ALLEVIATES LPS-INDUCED HK2 CELL APOPTOSIS AND INFLAMMATION INJURY VIA TARGETING MIR-215-5P/TRAF6/NF-KappaB AXIS IN SEPTIC ACUTE KIDNEY INJURY.

    KNOCKDOWN OF CIRC_0114428 ALLEVIATES LPS-INDUCED HK2 CELL APOPTOSIS AND INFLAMMATION INJURY VIA TARGETING MIR-215-5P/TRAF6/NF-ΚB AXIS IN SEPTIC ACUTE KIDNEY INJURY.
    Li Y, Zhang C, Zhao Z.

    04/22/2024
    A genetic variant in gene NDUFAF4 confers the risk of non-small cell lung cancer by perturbing hsa-miR-215 binding.

    A genetic variant in gene NDUFAF4 confers the risk of non-small cell lung cancer by perturbing hsa-miR-215 binding.
    Long T, Li J, Yin T, Liu K, Wang Y, Long J, Wang J, Cheng L.

    12/15/2023
    HIV infection is associated with upregulated circulating levels of the inflammaging miR-21-5p.

    HIV infection is associated with upregulated circulating levels of the inflammaging miR-21-5p.
    Meseguer-Donlo J, Soldado-Folgado J, Du J, González-Mena A, Blasco-Hernando F, Cañas-Ruano E, Nogués X, Knobel H, Garcia-Giralt N, Güerri-Fernández R.

    10/11/2023
    MicroRNA-215-5p promotes proliferation, invasion, and inhibits apoptosis in liposarcoma cells by targeting MDM2.

    MicroRNA-215-5p promotes proliferation, invasion, and inhibits apoptosis in liposarcoma cells by targeting MDM2.
    Song Z, Bai J, Jiang R, Wu J, Yang W., Free PMC Article

    07/7/2023
    HNRNPA2B1-mediated m[6]A modification of lncRNA MEG3 facilitates tumorigenesis and metastasis of non-small cell lung cancer by regulating miR-21-5p/PTEN axis.

    HNRNPA2B1-mediated m(6)A modification of lncRNA MEG3 facilitates tumorigenesis and metastasis of non-small cell lung cancer by regulating miR-21-5p/PTEN axis.
    Li K, Gong Q, Xiang XD, Guo G, Liu J, Zhao L, Li J, Chen N, Li H, Zhang LJ, Zhou CY, Wang ZY, Zhuang L., Free PMC Article

    06/15/2023
    Silencing miR-21-5p in sensory neurons reverses neuropathic allodynia via activation of TGF-beta-related pathway in macrophages.

    Silencing miR-21-5p in sensory neurons reverses neuropathic allodynia via activation of TGF-β-related pathway in macrophages.
    Zeboudj L, Sideris-Lampretsas G, Silva R, Al-Mudaris S, Picco F, Fox S, Chambers D, Malcangio M., Free PMC Article

    06/7/2023
    Potential plasma microRNAs signature miR-190b-5p, miR-215-5p and miR-527 as non-invasive biomarkers for prostate cancer.

    Potential plasma microRNAs signature miR-190b-5p, miR-215-5p and miR-527 as non-invasive biomarkers for prostate cancer.
    Khan MM, Serajuddin M, Bharadwaj M.

    03/3/2023
    miR-215-5p regulates osteoporosis development and osteogenic differentiation by targeting XIAP.

    miR-215-5p regulates osteoporosis development and osteogenic differentiation by targeting XIAP.
    Yin Z, Shen J, Wang Q, Wen L, Qu W, Zhang Y., Free PMC Article

    08/27/2022
    Micro-RNA-215 and -375 regulate thymidylate synthase protein expression in pleural mesothelioma and mediate epithelial to mesenchymal transition.

    Micro-RNA-215 and -375 regulate thymidylate synthase protein expression in pleural mesothelioma and mediate epithelial to mesenchymal transition.
    Napoli F, Rapa I, Izzo S, Rigutto A, Libener R, Riganti C, Bironzo P, Taulli R, Papotti M, Volante M, Scagliotti G, Righi L., Free PMC Article

    08/6/2022
    LncRNA SOX2OT facilitates LPS-induced inflammatory injury by regulating intercellular adhesion molecule 1 (ICAM1) via sponging miR-215-5p.

    LncRNA SOX2OT facilitates LPS-induced inflammatory injury by regulating intercellular adhesion molecule 1 (ICAM1) via sponging miR-215-5p.
    Zhu W, Peng F, Cui X, Li J, Sun C.

    05/21/2022
    Circulating Plasma MicroRNA in Patients With Active Acromegaly.

    Circulating Plasma MicroRNA in Patients With Active Acromegaly.
    Lutsenko A, Belaya Z, Nikitin A, Solodovnikov A, Lapshina A, Koshkin P, Vorontsova M, Rozhinskaya L, Melnichenko G, Dedov I.

    02/19/2022
    MicroRNA-215-5p Inhibits the Proliferation and Migration of Wilm's Tumor Cells by Targeting CRK.

    MicroRNA-215-5p Inhibits the Proliferation and Migration of Wilm's Tumor Cells by Targeting CRK.
    Li W, Lingdi L, Xiqiang D, Jiheng L, Xin T, Qin H, Haisha L., Free PMC Article

    02/12/2022
    Long non-coding RNA PCED1B antisense RNA 1 promotes gastric cancer progression via modulating microRNA-215-3p / C-X-C motif chemokine receptor 1 axis.

    Long non-coding RNA PCED1B antisense RNA 1 promotes gastric cancer progression via modulating microRNA-215-3p / C-X-C motif chemokine receptor 1 axis.
    Ren J, Xu N, Zhou R, Huang F, Zhang H, Li W., Free PMC Article

    12/18/2021
    Down-regulation of miR-215 attenuates lipopolysaccharide-induced inflammatory injury in CCD-18co cells by targeting GDF11 through the TLR4/NF-kB and JNK/p38 signaling pathways.

    Down-regulation of miR-215 attenuates lipopolysaccharide-induced inflammatory injury in CCD-18co cells by targeting GDF11 through the TLR4/NF-kB and JNK/p38 signaling pathways.
    Sun B, Xing K, Qi C, Yan K, Xu Y.

    11/6/2021
    Small extracellular vesicles containing miR-192/215 mediate hypoxia-induced cancer-associated fibroblast development in head and neck squamous cell carcinoma.

    Small extracellular vesicles containing miR-192/215 mediate hypoxia-induced cancer-associated fibroblast development in head and neck squamous cell carcinoma.
    Zhu G, Cao B, Liang X, Li L, Hao Y, Meng W, He C, Wang L, Li L.

    09/18/2021
    Integrated study of miR-215 promoting breast cancer cell apoptosis by targeting RAD54B.

    Integrated study of miR-215 promoting breast cancer cell apoptosis by targeting RAD54B.
    Wang M, Liao J, Tan C, Zhou H, Wang J, Wang K, Li Y, Wu W., Free PMC Article

    09/18/2021
    Interactome analysis of gene expression profiles identifies CDC6 as a potential therapeutic target modified by miR-215-5p in hepatocellular carcinoma.

    Interactome analysis of gene expression profiles identifies CDC6 as a potential therapeutic target modified by miR-215-5p in hepatocellular carcinoma.
    Xu H, Huang J, Hua S, Liang L, He X, Zhan M, Lu L, Chu J., Free PMC Article

    08/7/2021
    CircHIPK3 regulates melanoma cell behaviors by binding with miR-215-5p to upregulate YY1.

    CircHIPK3 regulates melanoma cell behaviors by binding with miR-215-5p to upregulate YY1.
    Zhu X, Sun J.

    07/17/2021
    Crosstalk between miR-215 and epithelial-mesenchymal transition specific markers (E-cadherin and N-cadherin) in different stages of chronic HCV Infection.

    Crosstalk between miR-215 and epithelial-mesenchymal transition specific markers (E-cadherin and N-cadherin) in different stages of chronic HCV Infection.
    Omran NM, El-Sherbini SM, Hegazy O, Elshaarawy AA, Talaat RM.

    07/17/2021
    Overexpression of serum extracellular vesicle microRNA-215-5p is associated with early tumor recurrence and poor prognosis of gastric cancer.

    Overexpression of serum extracellular vesicle microRNA-215-5p is associated with early tumor recurrence and poor prognosis of gastric cancer.
    Zhang Y, Huang F, Xu N, Wang J, Li D, Yin L., Free PMC Article

    05/29/2021
    Histone methyltransferase SET8 is regulated by miR-192/215 and induces oncogene-induced senescence via p53-dependent DNA damage in human gastric carcinoma cells.

    Histone methyltransferase SET8 is regulated by miR-192/215 and induces oncogene-induced senescence via p53-dependent DNA damage in human gastric carcinoma cells.
    Zhang X, Peng Y, Yuan Y, Gao Y, Hu F, Wang J, Zhu X, Feng X, Cheng Y, Wei Y, Fan X, Xie Y, Lv Y, Ashktorab H, Smoot D, Li S, Meltzer SJ, Hou G, Jin Z., Free PMC Article

    05/22/2021
    miR-215-5p is an anticancer gene in multiple myeloma by targeting RUNX1 and deactivating the PI3K/AKT/mTOR pathway.

    miR-215-5p is an anticancer gene in multiple myeloma by targeting RUNX1 and deactivating the PI3K/AKT/mTOR pathway.
    Liu S, Zhang Y, Huang C, Lin S.

    05/15/2021
    Long non-coding RNA FTX promotes gastric cancer progression by targeting miR-215.

    Long non-coding RNA FTX promotes gastric cancer progression by targeting miR-215.
    Zhang F, Wang XS, Tang B, Li PA, Wen Y, Yu PW.

    03/20/2021
    miRNA-192 and -215 activate Wnt/beta-catenin signaling pathway in gastric cancer via APC.

    miRNA-192 and -215 activate Wnt/β-catenin signaling pathway in gastric cancer via APC.
    Deng S, Zhang X, Qin Y, Chen W, Fan H, Feng X, Wang J, Yan R, Zhao Y, Cheng Y, Wei Y, Fan X, Ashktorab H, Smoot D, Meltzer SJ, Li S, Li K, Peng Y, Jin Z.

    03/13/2021
    MicroRNA-215 promoted the progression of nasopharyngeal carcinoma through targeting RB1 and activating Wnt/beta-catenin pathway.

    MicroRNA-215 promoted the progression of nasopharyngeal carcinoma through targeting RB1 and activating Wnt/β-catenin pathway.
    Zhang Y, Zhang H, Li X.

    02/13/2021
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