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    MIR154 microRNA 154 [ Homo sapiens (human) ]

    Gene ID: 406946, updated on 10-Oct-2023

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    LncRNA KCNQ10T1 shuttled by bone marrow mesenchymal stem cell-derived exosome inhibits sepsis via regulation of miR-154-3p/RNF19A axis.

    LncRNA KCNQ10T1 shuttled by bone marrow mesenchymal stem cell-derived exosome inhibits sepsis via regulation of miR-154-3p/RNF19A axis.
    Yuan H, Yu J, Liu C, Zhao H, Xue J, Liu J, Yang Y., Free PMC Article

    09/12/2023
    MicroRNA-154-5p suppresses cervical carcinoma growth and metastasis by silencing Cullin2 in vitro and in vivo.

    MicroRNA-154-5p suppresses cervical carcinoma growth and metastasis by silencing Cullin2 in vitro and in vivo.
    Li Y, Wei Y, Zhang H, Bai Y, Wang X, Li Q, Liu Y, Wang S, Wang J, Wen S, Li J, Zhao W., Free PMC Article

    07/10/2023
    Exosomes-derived miR-154-5p attenuates esophageal squamous cell carcinoma progression and angiogenesis by targeting kinesin family member 14.

    Exosomes-derived miR-154-5p attenuates esophageal squamous cell carcinoma progression and angiogenesis by targeting kinesin family member 14.
    Shou Y, Wang X, Liang Y, Liu X, Chen K., Free PMC Article

    03/26/2022
    Circ-ATAD1 is overexpressed in osteosarcoma (OS) and suppresses the maturation of miR-154-5p to increase cell invasion and migration.

    Circ-ATAD1 is overexpressed in osteosarcoma (OS) and suppresses the maturation of miR-154-5p to increase cell invasion and migration.
    Zhou J, Xu L, Yang P, Lin S, Huang H., Free PMC Article

    03/5/2022
    Circular RNA circABCC4 acts as a ceRNA of miR-154-5p to improve cell viability, migration and invasion of breast cancer cells in vitro.

    Circular RNA circABCC4 acts as a ceRNA of miR-154-5p to improve cell viability, migration and invasion of breast cancer cells in vitro.
    Jiang J, Cheng X., Free PMC Article

    12/11/2021
    SP1 activated-lncRNA SNHG1 mediates the development of epilepsy via miR-154-5p/TLR5 axis.

    SP1 activated-lncRNA SNHG1 mediates the development of epilepsy via miR-154-5p/TLR5 axis.
    Zhao MW, Qiu WJ, Yang P.

    10/9/2021
    Histone deacetylase 1 regulates the malignancy of oral cancer cells via miR-154-5p/PCNA axis.

    Histone deacetylase 1 regulates the malignancy of oral cancer cells via miR-154-5p/PCNA axis.
    Lv Y, Lu J, Liu X, Miao S, Mao X, Li B, Pei R, Xiang C.

    06/19/2021
    lncRNA DLGAP1-AS2 Knockdown Inhibits Hepatocellular Carcinoma Cell Migration and Invasion by Regulating miR-154-5p Methylation.

    lncRNA DLGAP1-AS2 Knockdown Inhibits Hepatocellular Carcinoma Cell Migration and Invasion by Regulating miR-154-5p Methylation.
    Chen K, Zhang Z, Yu A, Li J, Liu J, Zhang X., Free PMC Article

    05/8/2021
    Correlation between serum miR-154-5p and urinary albumin excretion rates in patients with type 2 diabetes mellitus: a cross-sectional cohort study.

    Correlation between serum miR-154-5p and urinary albumin excretion rates in patients with type 2 diabetes mellitus: a cross-sectional cohort study.
    Ren H, Wu C, Shao Y, Liu S, Zhou Y, Wang Q.

    05/8/2021
    Long non-coding RNA SNHG11 promotes cell proliferation, invasion and migration in glioma by targeting miR-154-5p.

    Long non-coding RNA SNHG11 promotes cell proliferation, invasion and migration in glioma by targeting miR-154-5p.
    Geng YB, Xu C, Wang Y, Zhang LW.

    04/3/2021
    miR-154-3p and miR-487-3p synergistically modulate RHOA signaling in the carcinogenesis of thyroid cancer.

    miR-154-3p and miR-487-3p synergistically modulate RHOA signaling in the carcinogenesis of thyroid cancer.
    Fan XD, Luo Y, Wang J, An N., Free PMC Article

    03/20/2021
    Long intergenic non-coding RNA 1939 eliminates proliferation and migration of human renal cell carcinoma (RCC) cells by down-regulation of miR-154.

    Long intergenic non-coding RNA 1939 eliminates proliferation and migration of human renal cell carcinoma (RCC) cells by down-regulation of miR-154.
    Zhang R, Zhang W, Xu B, Lv C, Hou J, Zhang G.

    01/16/2021
    Upregulation of miRNA-154-5p prevents the tumorigenesis of osteosarcoma.

    Upregulation of miRNA-154-5p prevents the tumorigenesis of osteosarcoma.
    Tian Q, Gu Y, Wang F, Zhou L, Dai Z, Liu H, Wu X, Wang X, Liu Y, Chen S, Han Q.

    11/21/2020
    MiR-154 inhibits cells proliferation and metastasis in melanoma by targeting AURKA and serves as a novel prognostic indicator.

    MiR-154 inhibits cells proliferation and metastasis in melanoma by targeting AURKA and serves as a novel prognostic indicator.
    Wang J, Fang Y, Liu YF, Wang X, Wang XL, Wang RY, Meng ZD.

    09/19/2020
    Circ_101064 regulates the proliferation, invasion and migration of glioma cells through miR-154-5p/ PIWIL1 axis.

    Circ_101064 regulates the proliferation, invasion and migration of glioma cells through miR-154-5p/ PIWIL1 axis.
    Zhou H, Zhang Y, Lai Y, Xu C, Cheng Y.

    09/12/2020
    Data show that 56% of Bcl2-associated athanogene 3 protein (BAG3+)/ dilated cardiomyopathy (DCM+) significantly co-expressed mir-154-5p and mir-182-5p, suggesting that co-expression of mir-154-5p and mir-182-5p may potentially show diagnostic value.

    Differential expression of circulating miRNAs as a novel tool to assess BAG3-associated familial dilated cardiomyopathy.
    Zaragoza C, Saura M, Hernández I, Ramirez-Carracedo R, García-García F, Zamorano JL, Mangas A, Toro R., Free PMC Article

    02/29/2020
    Oxidative injury in HUVECs was regulated by microRNA-154 targeting the Wnt/ss-catenin signaling pathway.

    MicroRNA-154 Targets the Wnt/β-Catenin Signaling Pathway Following Injury to Human Vascular Endothelial Cells by Hydrogen Peroxide.
    Li Y, Meng R., Free PMC Article

    02/15/2020
    hsa-miR-154-5p, alone or in combination with hsa-miR-196b-5p, hsa-miR-378a-3p and hsa-miR-33a-5p and the clinical parameters of BMI and age, may be applicable for non-invasive diagnosis of the endrometriosis

    hsa-miRNA-154-5p expression in plasma of endometriosis patients is a potential diagnostic marker for the disease.
    Pateisky P, Pils D, Szabo L, Kuessel L, Husslein H, Schmitz A, Wenzl R, Yotova I.

    11/16/2019
    MiR-154 can inhibit GSK-3beta expression by activating Wnt/beta-catenin signaling pathway, which promotes myocardial fibrosis

    MiR-154 promotes myocardial fibrosis through β-catenin signaling pathway.
    Dong P, Liu WJ, Wang ZH.

    11/9/2019
    the results of our studies illuminate how SNHG1 formed a regulatory network to confer an oncogenic function in colorectal cancer and suggest that SNHG1 may serve as a potential target for colorectal cancer diagnosis and treatment.

    The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p.
    Xu M, Chen X, Lin K, Zeng K, Liu X, Pan B, Xu X, Xu T, Hu X, Sun L, He B, Pan Y, Sun H, Wang S., Free PMC Article

    04/27/2019
    miR-154 inhibits proliferation and induces apoptosis of human skin SCC cells by down-regulating WHSC1 and blocking the P53 signaling pathway

    Inhibitory effect of microRNA-154 targeting WHSC1 on cell proliferation of human skin squamous cell carcinoma through mediating the P53 signaling pathway.
    Chen HQ, Gao D.

    03/9/2019
    Low miR154 expression is associated with Growth and Invasion of Gastric Cancer.

    MicroRNA-154 Inhibits the Growth and Invasion of Gastric Cancer Cells by Targeting DIXDC1/WNT Signaling.
    Song J, Guan Z, Li M, Sha S, Song C, Gao Z, Zhao Y., Free PMC Article

    02/9/2019
    miR154 expression was significantly downregulated and negatively correlated with ATG7 expression in bladder cancer (BCa) tissues and cell lines. miR154 expression was associated with advanced T stage, lymphatic invasion, and distant metastasis. A xenograft study revealed that miR154 inhibited BCa cell growth in vivo and suppressed ATG7 expression.

    MicroRNA‑154 functions as a tumor suppressor in bladder cancer by directly targeting ATG7.
    Zhang J, Mao S, Wang L, Zhang W, Zhang Z, Guo Y, Wu Y, Yi F, Yao X., Free PMC Article

    02/2/2019
    High miR154 expression is associated with renal cell carcinoma.

    Oncogene miR-154-5p regulates cellular function and acts as a molecular marker with poor prognosis in renal cell carcinoma.
    Lin C, Li Z, Chen P, Quan J, Pan X, Zhao L, Zhou L, Lai Y, He T, Xu W, Xu J, Guan X, Li H, Yang S, Hu Y, Lai Y.

    09/29/2018
    Data found that miR-154 was downregulated in bladder cancer (BC) tissues and lower miR-154 expression levels were strongly associated with worse overall survival rates of patients with BC. Further study suggested that this was due to decreased inhibition of BC cell proliferation, migration and invasion mediated by miR-154.

    MicroRNA-154 as a prognostic factor in bladder cancer inhibits cellular malignancy by targeting RSF1 and RUNX2.
    Zhao X, Ji Z, Xie Y, Liu G, Li H., Free PMC Article

    07/28/2018
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