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    MIR105-2 microRNA 105-2 [ Homo sapiens (human) ]

    Gene ID: 406898, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Circular RNA circMRPS35 represses malignant progression in osteosarcoma cells via targeting miR-105-5p/FOXO1.

    Circular RNA circMRPS35 represses malignant progression in osteosarcoma cells via targeting miR-105-5p/FOXO1.
    Jiang C, Jiang Z, Zhang X., Free PMC Article

    10/1/2024
    MiR-105 enhances osteogenic differentiation of hADSCs via the targeted regulation of SOX9.

    MiR-105 enhances osteogenic differentiation of hADSCs via the targeted regulation of SOX9.
    Li CL, Wang K, Li ZW, Xiong YB, Liu JH, Meng GH, Qin F.

    01/22/2022
    Role of hsamiR105 during the pathogenesis of paclitaxel resistance and its clinical implication in ovarian cancer.

    Role of hsa‑miR‑105 during the pathogenesis of paclitaxel resistance and its clinical implication in ovarian cancer.
    Li M, Zhang S, Ma Y, Yang Y, An R., Free PMC Article

    11/13/2021
    Cancer-secreted miRNAs regulate amino-acid-induced mTORC1 signaling and fibroblast protein synthesis.

    Cancer-secreted miRNAs regulate amino-acid-induced mTORC1 signaling and fibroblast protein synthesis.
    Fong MY, Yan W, Ghassemian M, Wu X, Zhou X, Cao M, Jiang L, Wang J, Liu X, Zhang J, Wang SE., Free PMC Article

    06/5/2021
    MiR-105-3p acts as an oncogene to promote the proliferation and metastasis of breast cancer cells by targeting GOLIM4.

    MiR-105-3p acts as an oncogene to promote the proliferation and metastasis of breast cancer cells by targeting GOLIM4.
    Lin B, Liu C, Shi E, Jin Q, Zhao W, Wang J, Ji R., Free PMC Article

    05/8/2021
    MiR-105 inhibits gastric cancer cells metastasis, epithelial-mesenchymal transition by targeting SOX9.

    MiR-105 inhibits gastric cancer cells metastasis, epithelial-mesenchymal transition by targeting SOX9.
    Shang JC, Yu GZ, Ji ZW, Wang XQ, Xia L.

    10/3/2020
    Up-regulation of miRNA-105 inhibits the progression of gastric carcinoma by directly targeting SOX9.

    Up-regulation of miRNA-105 inhibits the progression of gastric carcinoma by directly targeting SOX9.
    Jin M, Zhang GW, Shan CL, Zhang H, Wang ZG, Liu SQ, Wang SQ.

    09/12/2020
    Higher level of miR-105-2 predicts poorer prognosis in esophageal cancer patients, and miR-105 can promote esophageal cancer cell proliferation, migration, and invasion.

    MicroRNA-105 plays an independent prognostic role in esophageal cancer and acts as an oncogene.
    Gao R, Wang Z, Liu Q, Yang C.

    08/1/2020
    miR-105 promotes MYC-mediated metabolic reprogramming of breast cancer stromal cells, contributing to sustained tumour growth by conditioning the shared metabolic environment.

    Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells.
    Yan W, Wu X, Zhou W, Fong MY, Cao M, Liu J, Liu X, Chen CH, Fadare O, Pizzo DP, Wu J, Liu L, Liu X, Chin AR, Ren X, Chen Y, Locasale JW, Wang SE., Free PMC Article

    04/13/2019
    GABRA3 harbors a microRNA (miR-105), which has recently been identified as a promoter of cancer metastasis by its ability to weaken vascular endothelial barriers following exosomal secretion.

    A novel cancer-germline transcript carrying pro-metastatic miR-105 and TET-targeting miR-767 induced by DNA hypomethylation in tumors.
    Loriot A, Van Tongelen A, Blanco J, Klaessens S, Cannuyer J, van Baren N, Decottignies A, De Smet C., Free PMC Article

    07/25/2015
    Data indicate that adult CD34(+) cells express endogenous miR-105 during megakaryocyte differentiation.

    MicroRNA screen of human embryonic stem cell differentiation reveals miR-105 as an enhancer of megakaryopoiesis from adult CD34+ cells.
    Kamat V, Paluru P, Myint M, French DL, Gadue P, Diamond SL., Free PMC Article

    12/20/2014
    Data indicate CDK6 as a putative target of miR-105 which is likely a main contributor to the inhibition of tumour cell growth observed in our assays.

    miR-105 inhibits prostate tumour growth by suppressing CDK6 levels.
    Honeywell DR, Cabrita MA, Zhao H, Dimitroulakos J, Addison CL., Free PMC Article

    08/23/2014
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