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    BMAL1 basic helix-loop-helix ARNT like 1 [ Homo sapiens (human) ]

    Gene ID: 406, updated on 12-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Bmal1 regulates the stemness and tumorigenesis of gliomas with the Wnt/beta-catenin signaling pathway.

    Bmal1 regulates the stemness and tumorigenesis of gliomas with the Wnt/β-catenin signaling pathway.
    Han Q, Li M, Su D, Fan H, Xia H.

    11/7/2024
    Arntl-induced upregulation of DUSP1 inhibits tumor progression in esophageal squamous cell carcinoma by inactivating ERK signaling.

    Arntl-induced upregulation of DUSP1 inhibits tumor progression in esophageal squamous cell carcinoma by inactivating ERK signaling.
    Wang J, Jia Q, Sun J, Wu S, Wei L, Yao W., Free PMC Article

    10/8/2024
    BMAL1 plays a crucial role in immune homeostasis during sepsis-induced acute lung injury.

    BMAL1 plays a crucial role in immune homeostasis during sepsis-induced acute lung injury.
    Zeng T, Liang L, Deng W, Xie M, Zhao M, Wang S, Liu J, Yang M.

    08/28/2024
    Circadian disruption reduces MUC4 expression via the clock molecule BMAL1 during dry eye development.

    Circadian disruption reduces MUC4 expression via the clock molecule BMAL1 during dry eye development.
    Zeng H, Yang X, Liao K, Zuo X, Liang L, He D, Ju R, Wang B, Yuan J., Free PMC Article

    08/6/2024
    Circadian Clock Gene bmal1 Acts as a Tumor Suppressor Gene in a Mice Model of Human Glioblastoma.

    Circadian Clock Gene bmal1 Acts as a Tumor Suppressor Gene in a Mice Model of Human Glioblastoma.
    Trebucq LL, Salvatore N, Wagner PM, Golombek DA, Chiesa JJ.

    07/22/2024
    Phosphorylation of DNA-binding domains of CLOCK-BMAL1 complex for PER-dependent inhibition in circadian clock of mammalian cells.

    Phosphorylation of DNA-binding domains of CLOCK-BMAL1 complex for PER-dependent inhibition in circadian clock of mammalian cells.
    Otobe Y, Jeong EM, Ito S, Shinohara Y, Kurabayashi N, Aiba A, Fukada Y, Kim JK, Yoshitane H., Free PMC Article

    06/12/2024
    Targeting BMAL1 reverses drug resistance of acute myeloid leukemia cells and promotes ferroptosis through HMGB1-GPX4 signaling pathway.

    Targeting BMAL1 reverses drug resistance of acute myeloid leukemia cells and promotes ferroptosis through HMGB1-GPX4 signaling pathway.
    Zheng H, Wu T, Lin Z, Wang D, Zhang J, Zeng T, Liu L, Shen J, Zhao M, Li JD, Yang M., Free PMC Article

    05/9/2024
    Melatonin ameliorates hepatic fibrosis via the melatonin receptor 2-mediated upregulation of BMAL1 and anti-oxidative enzymes.

    Melatonin ameliorates hepatic fibrosis via the melatonin receptor 2-mediated upregulation of BMAL1 and anti-oxidative enzymes.
    Kim JI, Cheon HG.

    02/23/2024
    BMAL1 positively correlates with genes regulating steroidogenesis in human luteinized granulosa cells.

    BMAL1 positively correlates with genes regulating steroidogenesis in human luteinized granulosa cells.
    Kawamura T, Dai Y, Ono M, Kikuchi T, Yamanaka A, Ueno K, Kojima J, Fujiwara T, Daikoku T, Maida Y, Ando H, Fujiwara H, Kuji N, Nishi H.

    02/6/2024
    The clock gene Bmal1 controls inflammatory mediators in rheumatoid arthritis fibroblast-like synoviocytes.

    The clock gene Bmal1 controls inflammatory mediators in rheumatoid arthritis fibroblast-like synoviocytes.
    Kaneshiro K, Nakagawa K, Tsukamoto H, Matsuoka G, Okuno S, Tateishi K, Terashima Y, Shibanuma N, Yoshida K, Hashiramoto A.

    01/4/2024
    Role of Bmal1 and Gut Microbiota in Alzheimer's Disease and Parkinson's Disease Pathophysiology: The Probable Effect of Melatonin on Their Association.

    Role of Bmal1 and Gut Microbiota in Alzheimer's Disease and Parkinson's Disease Pathophysiology: The Probable Effect of Melatonin on Their Association.
    Khezri MR, Esmaeili A, Ghasemnejad-Berenji M.

    11/2/2023
    Circadian gene ARNTL initiates circGUCY1A2 transcription to suppress non-small cell lung cancer progression via miR-200c-3p/PTEN signaling.

    Circadian gene ARNTL initiates circGUCY1A2 transcription to suppress non-small cell lung cancer progression via miR-200c-3p/PTEN signaling.
    Zhao D, Dong Y, Duan M, He D, Xie Q, Peng W, Cui W, Jiang J, Cheng Y, Zhang H, Tang F, Zhang C, Gao Y, Duan C., Free PMC Article

    09/27/2023
    New insights into the mechanisms of diabetic kidney disease: Role of circadian rhythm and Bmal1.

    New insights into the mechanisms of diabetic kidney disease: Role of circadian rhythm and Bmal1.
    Peng Z, Liang Y, Liu X, Shao J, Hu N, Zhang X.

    09/22/2023
    Association of BMAL1 clock gene polymorphisms with fasting glucose in children.

    Association of BMAL1 clock gene polymorphisms with fasting glucose in children.
    Yang YD, Zeng Y, Li J, Zhou JH, He QY, Zheng CJ, Reichetzeder C, Krämer BK, Hocher B., Free PMC Article

    08/3/2023
    Artificial induction of circadian rhythm by combining exogenous BMAL1 expression and polycomb repressive complex 2 inhibition in human induced pluripotent stem cells.

    Artificial induction of circadian rhythm by combining exogenous BMAL1 expression and polycomb repressive complex 2 inhibition in human induced pluripotent stem cells.
    Kaneko H, Kaitsuka T, Tomizawa K., Free PMC Article

    07/12/2023
    Bmal1 and Gut-lung axis in SARS-CoV-2 infection: New insight into the effects of melatonin on COVID-19 patients?

    Bmal1 and Gut-lung axis in SARS-CoV-2 infection: New insight into the effects of melatonin on COVID-19 patients?
    Khezri MR, Varzandeh R, Ghasemnejad-Berenji M., Free PMC Article

    06/26/2023
    Protective effects of brain and muscle ARNT-like gene 1 on oxidized low-density lipoprotein-induced human brain microvascular endothelial cell injury by alleviating ferroptosis.

    Protective effects of brain and muscle ARNT-like gene 1 on oxidized low-density lipoprotein-induced human brain microvascular endothelial cell injury by alleviating ferroptosis.
    Yu S, Zeng Y, Ruan C, Bai L, Liang Z.

    06/26/2023
    Is BMAL1 Just One Song Impacting the Circadian Dance of Lung Injury?

    Is BMAL1 Just One Song Impacting the Circadian Dance of Lung Injury?
    Stewart NH, Sundar IK., Free PMC Article

    06/22/2023
    BMAL1 Regulates Glucokinase Expression Through E-Box Elements In Vitro.

    BMAL1 Regulates Glucokinase Expression Through E-Box Elements In Vitro.
    Llanos P, Ordenes P, Rhoads DB, Santibanez JF, García-Robles M, Millán C.

    04/26/2023
    Melatonin upregulates BMAL1 to attenuate chronic sleep deprivation-related cognitive impairment by alleviating oxidative stress.

    Melatonin upregulates BMAL1 to attenuate chronic sleep deprivation-related cognitive impairment by alleviating oxidative stress.
    Hu Y, Yin J, Yang G., Free PMC Article

    02/11/2023
    The Circadian Clock, Nutritional Signals and Reproduction: A Close Relationship.

    The Circadian Clock, Nutritional Signals and Reproduction: A Close Relationship.
    Ono M, Ando H, Daikoku T, Fujiwara T, Mieda M, Mizumoto Y, Iizuka T, Kagami K, Hosono T, Nomura S, Toyoda N, Sekizuka-Kagami N, Maida Y, Kuji N, Nishi H, Fujiwara H., Free PMC Article

    01/28/2023
    Circadian regulator BMAL1::CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle.

    Circadian regulator BMAL1::CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle.
    Qu M, Zhang G, Qu H, Vu A, Wu R, Tsukamoto H, Jia Z, Huang W, Lenz HJ, Rich JN, Kay SA., Free PMC Article

    01/11/2023
    BMAL1/FOXA2-induced rhythmic fluctuations in IL-6 contribute to nocturnal asthma attacks.

    BMAL1/FOXA2-induced rhythmic fluctuations in IL-6 contribute to nocturnal asthma attacks.
    Tang L, Liu L, Sun X, Hu P, Zhang H, Wang B, Zhang X, Jiang J, Zhao X, Shi X., Free PMC Article

    01/11/2023
    Expression of the Circadian Clock Gene ARNTL associated with DNA repair gene and prognosis of patient with osteosarcoma.

    Expression of the Circadian Clock Gene ARNTL associated with DNA repair gene and prognosis of patient with osteosarcoma.
    Kong D, Liu Y, Zhang M.

    12/17/2022
    Sex-specific genetic association of brain and muscle Arnt-like protein-1 (BMAL1) and obesity in Chinese youth.

    Sex-specific genetic association of brain and muscle Arnt-like protein-1 (BMAL1) and obesity in Chinese youth.
    Fang Z, Zhu L, Zhang T, Jin Y, Chen Y, Yao Y.

    12/10/2022
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