LncRNA HAGLR regulates gastric cancer progression by regulating the miR-20a-5p/E2F1 axis. | LncRNA HAGLR regulates gastric cancer progression by regulating the miR-20a-5p/E2F1 axis. Liu Q, Li Y, Tan B, Zhao Q, Fan L, Zhang Z, Wang D, Zhao X, Liu Y, Liu W., Free PMC Article | 10/25/2024 |
HAGLR, stabilized by m6A modification, triggers PTEN-Akt signaling cascade-mediated RPE cell pyroptosis via sponging miR-106b-5p. | HAGLR, stabilized by m6A modification, triggers PTEN-Akt signaling cascade-mediated RPE cell pyroptosis via sponging miR-106b-5p. Luo R, Li L, Han Q, Fu J, Xiao F. | 01/26/2024 |
Long non-coding RNA Homeobox D gene cluster antisense growth-associated long noncoding RNA/microRNA-182-5p/Homeobox protein A10 alleviates postmenopausal osteoporosis via accelerating osteoblast differentiation of bone marrow mesenchymal stem cells. | Long non-coding RNA Homeobox D gene cluster antisense growth-associated long noncoding RNA/microRNA-182-5p/Homeobox protein A10 alleviates postmenopausal osteoporosis via accelerating osteoblast differentiation of bone marrow mesenchymal stem cells. Huang Y, Tao M, Yan S, He X., Free PMC Article | 10/4/2023 |
LncRNA HAGLR May Aggravate Melanoma Malignancy Via miR-4644/ASB11 Pathway. | LncRNA HAGLR May Aggravate Melanoma Malignancy Via miR-4644/ASB11 Pathway. Luo L, Zhang W, Li Z. | 09/7/2023 |
LncRNA HOXD-AS1 promotes oral squamous cell carcinoma by sponging miR-203a-5p. | LncRNA HOXD-AS1 promotes oral squamous cell carcinoma by sponging miR-203a-5p. Zhang Y, Wang F, Yu Y. | 04/24/2023 |
LncRNA HAGLR silencing inhibits IL-1beta-induced chondrocytes inflammatory injury via miR-130a-3p/JAK1 axis. | LncRNA HAGLR silencing inhibits IL-1β-induced chondrocytes inflammatory injury via miR-130a-3p/JAK1 axis. Zuo Y, Xiong C, Gan X, Xie W, Yan X, Chen Y, Li X., Free PMC Article | 03/22/2023 |
Knockdown of lncRNA HAGLR promotes Treg cell differentiation through increasing the RUNX3 level in dermatomyositis. | Knockdown of lncRNA HAGLR promotes Treg cell differentiation through increasing the RUNX3 level in dermatomyositis. Yan W, Wang L, Chen Z, Gu C, Chen C, Liu X, Ye Q. | 05/28/2022 |
Long noncoding RNA HOXD-AS1 promotes the progression of pancreatic cancer through miR-664b-3p/PLAC8 axis. | Long noncoding RNA HOXD-AS1 promotes the progression of pancreatic cancer through miR-664b-3p/PLAC8 axis. Chen L, Niu W, Zhu D, Shao W, Qian Y. | 04/16/2022 |
Exosomal long noncoding RNA HOXD-AS1 promotes prostate cancer metastasis via miR-361-5p/FOXM1 axis. | Exosomal long noncoding RNA HOXD-AS1 promotes prostate cancer metastasis via miR-361-5p/FOXM1 axis. Jiang Y, Zhao H, Chen Y, Li K, Li T, Chen J, Zhang B, Guo C, Qing L, Shen J, Liu X, Gu P., Free PMC Article | 04/16/2022 |
Long noncoding RNA HAGLR sponges miR-338-3p to promote 5-Fu resistance in gastric cancer through targeting the LDHA-glycolysis pathway. | Long noncoding RNA HAGLR sponges miR-338-3p to promote 5-Fu resistance in gastric cancer through targeting the LDHA-glycolysis pathway. Hu J, Huang L, Ding Q, Lv J, Chen Z., Free PMC Article | 04/9/2022 |
LncRNA-HAGLR motivates triple negative breast cancer progression by regulation of WNT2 via sponging miR-335-3p. | LncRNA-HAGLR motivates triple negative breast cancer progression by regulation of WNT2 via sponging miR-335-3p. Jin L, Luo C, Wu X, Li M, Wu S, Feng Y., Free PMC Article | 01/15/2022 |
HAGLR aggravates neuropathic pain and promotes inflammatory response and apoptosis of lipopolysaccharide-treated SH-SY5Y cells by sequestering miR-182-5p from ATAT1 and activating NLRP3 inflammasome. | HAGLR aggravates neuropathic pain and promotes inflammatory response and apoptosis of lipopolysaccharide-treated SH-SY5Y cells by sequestering miR-182-5p from ATAT1 and activating NLRP3 inflammasome. Zhang Q, Zhou L, Xie H, Zhang H, Gao X. | 11/22/2021 |
LncRNA HAGLR exacerbates hepatocellular carcinoma through negatively regulating miR-6785-5p. | LncRNA HAGLR exacerbates hepatocellular carcinoma through negatively regulating miR-6785-5p. Li YH, Huang GM, Wang W, Zang HL. | 05/8/2021 |
HOXD-AS1 facilitates cell migration and invasion as an oncogenic lncRNA by competitively binding to miR-877-3p and upregulating FGF2 in human cervical cancer. | HOXD-AS1 facilitates cell migration and invasion as an oncogenic lncRNA by competitively binding to miR-877-3p and upregulating FGF2 in human cervical cancer. Chen S, Li K., Free PMC Article | 04/24/2021 |
Spliceosome-Associated microRNAs Signify Breast Cancer Cells and Portray Potential Novel Nuclear Targets. | Spliceosome-Associated microRNAs Signify Breast Cancer Cells and Portray Potential Novel Nuclear Targets. Mahlab-Aviv S, Zohar K, Cohen Y, Peretz AR, Eliyahu T, Linial M, Sperling R., Free PMC Article | 03/28/2021 |
Silencing of long noncoding RNA HOXD-AS1 inhibits proliferation, cell cycle progression, migration and invasion of hepatocellular carcinoma cells through MEK/ERK pathway. | Silencing of long noncoding RNA HOXD-AS1 inhibits proliferation, cell cycle progression, migration and invasion of hepatocellular carcinoma cells through MEK/ERK pathway. Sun J, Guo Y, Bie B, Zhu M, Tian H, Tian J, Li J, Yang Y, Ji F, Kong G, Li Z. | 02/27/2021 |
Long Noncoding RNA HOXD-AS1 Promotes the Proliferation, Migration, and Invasion of Colorectal Cancer via the miR-526b-3p/CCND1 Axis. | Long Noncoding RNA HOXD-AS1 Promotes the Proliferation, Migration, and Invasion of Colorectal Cancer via the miR-526b-3p/CCND1 Axis. Yan F, Ma Y, Liu L, Li L, Deng J, Sun J. | 12/12/2020 |
HOXD-AS1: a novel oncogenic long intergenic non-coding RNA in humans. | HOXD-AS1: a novel oncogenic long intergenic non-coding RNA in humans. Xie SC, Yang YJ, Zhang JQ, Zhou S, Xie SW, Hua YY. | 09/12/2020 |
HOXD-AS1 is upregulated in human breast cancer.HOXD-AS1 promotes breast cancer cell proliferation and cell cycle progression.HOXD-AS1 serves as a competing endogenous RNA to regulate miR-421 expression in breast cancer. | Long noncoding RNA HOXD-AS1 induces epithelial-mesenchymal transition in breast cancer by acting as a competing endogenous RNA of miR-421. Li Y, Han X, Li Q, Wang C, Lou Z, Wang X. | 08/12/2020 |
The study in vitro suggested reduced HOXD-AS1 expression inhibited papillary thyroid cancer cell proliferation, migration, and invasion, and promoted cell-cycle arrest. In conclusion, HOXD-AS1 is a biomarker for predicting clinical progression in papillary thyroid cancer | HOXD-AS1 is a predictor of clinical progression and functions as an oncogenic lncRNAs in papillary thyroid cancer. Xu K, Feng Y. | 07/18/2020 |
HAGLR was frequently down-regulated in lung adenocarcinoma (LUAD). Decreased HAGLR expression was clinically associated with shorter survival. HAGLR could physically interact with DNMT1, and recruit DNMT1 on E2F1 promoter to increase local DNA methylation. HAGLR promoted LUAD progression by recruiting DNMT1 to modulate the promoter methylation and expression of E2F1. | Long non-coding RNA-HAGLR suppressed tumor growth of lung adenocarcinoma through epigenetically silencing E2F1. Guo X, Chen Z, Zhao L, Cheng D, Song W, Zhang X. | 06/27/2020 |
Elevated HAGLR expression is associated with epithelial-mesenchymal transition and metastatic potential in esophageal cancer. | Long noncoding RNA HAGLR acts as a microRNA-143-5p sponge to regulate epithelial-mesenchymal transition and metastatic potential in esophageal cancer by regulating LAMP3. Yang C, Shen S, Zheng X, Ye K, Sun Y, Lu Y, Ge H. | 05/30/2020 |
HOXD-AS1 participates in the development and progression of preeclampsia by regulating trophoblast proliferation via the MAPK pathway. | LncRNA HOXD-AS1 promotes preeclampsia progression via MAPK pathway. Jiang J, Zhao ZM. | 12/14/2019 |
Nuclear lncRNA HOXD-AS1 suppresses colorectal carcinoma growth and metastasis via inhibiting HOXD3-induced ITGB3 transcriptional activation and MAPK/AKT signaling. | Nuclear lncRNA HOXD-AS1 suppresses colorectal carcinoma growth and metastasis via inhibiting HOXD3-induced integrin β3 transcriptional activating and MAPK/AKT signalling. Yang MH, Zhao L, Wang L, Ou-Yang W, Hu SS, Li WL, Ai ML, Wang YQ, Han Y, Li TT, Ding YQ, Wang S., Free PMC Article | 06/15/2019 |
HOXD-AS1/miR-186-5p/PIK3R3 is a novel pathway to promote cell migration, invasion, and epithelial-mesenchymal transition in epithelial ovarian cancer | HOXD-AS1 promotes the epithelial to mesenchymal transition of ovarian cancer cells by regulating miR-186-5p and PIK3R3. Dong S, Wang R, Wang H, Ding Q, Zhou X, Wang J, Zhang K, Long Y, Lu S, Hong T, Ren H, Wong K, Sheng X, Wang Y, Zeng Y., Free PMC Article | 06/15/2019 |