| Ablation of conceptus PTGS2 expression does not alter early conceptus development and establishment of pregnancy in the pigdagger. | Ablation of conceptus PTGS2 expression does not alter early conceptus development and establishment of pregnancy in the pig†.
Pfeiffer CA, Meyer AE, Brooks KE, Chen PR, Milano-Foster J, Spate LD, Benne JA, Cecil RF, Samuel MS, Ciernia LA, Spinka CM, Smith MF, Wells KD, Spencer TE, Prather RS, Geisert RD., Free PMC Article | 06/19/2021 |
| These findings suggest that nuclear factor kappa B(NF-kappaB) and cyclooxygenase-2 play roles in epidermal cell regeneration following beta-irradiation of mini-pig skin. | β-irradiation (¹⁶⁶Ho patch)-induced skin injury in mini-pigs: effects on NF-κB and COX-2 expression in the skin.
Kim JS, Rhim KJ, Jang WS, Lee SJ, Son Y, Lee SS, Park S, Lim SM., Free PMC Article | 03/26/2016 |
| COX2 expression is upregulated in CAVD, and its activity contributes to osteogenic gene induction and valve calcification in vitro and in vivo. | COX2 inhibition reduces aortic valve calcification in vivo.
Wirrig EE, Gomez MV, Hinton RB, Yutzey KE., Free PMC Article | 06/6/2015 |
| These results suggest that COX-2 plays a role in the pathogenesis of Mycoplasma hyopneumoniae -infection. | Cyclooxygenase-2 expression in pigs infected experimentally with Mycoplasma hyopneumoniae.
Andrada M, Quesada-Canales O, Suárez-Bonnet A, Paz-Sánchez Y, Espinosa de Los Monteros A, Rodríguez F. | 04/25/2015 |
| Brain death increases the expression of COX-1 and COX-2 mRNA in the renal medulla | Brain death increases COX-1 and COX-2 expression in the renal medulla in a pig model.
Hvas CL, Nørregaard R, Nielsen TK, Barklin A, Tønnesen E. | 09/13/2014 |
| COC-2 inhibitors did not decrease collateral-dependent blood flow to the myocardium in a model of chronic myocardial ischemia. | Effects of selective cyclooxygenase-2 and nonselective cyclooxygenase inhibition on ischemic myocardium.
Robich MP, Chu LM, Feng J, Burgess TA, Laham RJ, Bianchi C, Sellke FW., Free PMC Article | 11/13/2010 |
| COX-2 is differentially expressed in normal versus lungworm-infected lungs of pigs and is likely to be involved in the pathogenesis of porcine parasitic bronchopneumonia. | 5-lipoxygenase and cyclooxygenase-2 in porcine parasitic bronchopneumonia: immunohistochemical and biochemical investigations.
Marruchella G, Giacominelli-Stuffler R, Baffoni M, Maccarrone M. | 05/31/2010 |
| In porcine vas deferens epithelial cell monolayers, increases in anion secretion were associated with preferential upregulation of PTGS2 at the mRNA and protein levels. | Testosterone upregulates anion secretion across porcine vas deferens epithelia in vitro.
Pierucci-Alves F, Duncan CL, Schultz BD., Free PMC Article | 01/21/2010 |
| myocardial infarction induced proinflammatory gene and protein expression in peripheral blood mononuclear cells of tissue factor cyclo-oxygenase-2, monocyte chemoattractant protein-1 and CRP | Short-term myocardial ischemia induces cardiac modified C-reactive protein expression and proinflammatory gene (cyclo-oxygenase-2, monocyte chemoattractant protein-1, and tissue factor) upregulation in peripheral blood mononuclear cells.
Vilahur G, Hernández-Vera R, Molins B, Casaní L, Duran X, Padró T, Badimon L. | 01/21/2010 |
| expression appears to be positively and negatively regulated by p38 MAPK and JNK pathways; alternatively, ERK1/2 appear to be involved in COX-2-independent reparative events that remain to be defined | Mitogen-activated protein kinases regulate COX-2 and mucosal recovery in ischemic-injured porcine ileum.
Shifflett DE, Jones SL, Moeser AJ, Blikslager AT. | 01/21/2010 |
| Administration of estrogen early in pregnancy alters endometrial prostaglandin-endoperoxide synthase 2 (PTGS2) mRNA and protein expression, which may disrupt pregnancy causing total embryonic loss during implantation in the pig. | Expression of porcine endometrial prostaglandin synthase during the estrous cycle and early pregnancy, and following endocrine disruption of pregnancy.
Ashworth MD, Ross JW, Hu J, White FJ, Stein DR, Desilva U, Johnson GA, Spencer TE, Geisert RD. | 01/21/2010 |
| The effect of EGF on pro-inflammatory cytokines, tumor necrosis factor-alpha (TNF-alpha) and cyclooxygenase-2 (COX-2), levels during wound healing in swine is reported. | Expression of tumor necrosis factor-alpha and cyclooxygenase-2 mRNA in porcine split-thickness wounds treated with epidermal growth factor by quantitative real-time PCR.
Jung K, Park HJ, Kim YH, Hong JP. | 01/21/2010 |
| Neutrophils augment recovery of transepithelial electrical resistance in ischemia-injured ileal mucosa via IL-1beta-dependent upregulation of COX-2. (Cyclooxygenase 2) | Neutrophils augment recovery of porcine ischemia-injured ileal mucosa by an IL-1beta- and COX-2-dependent mechanism.
Shifflett DE, Bottone FG Jr, Young KM, Moeser AJ, Jones SL, Blikslager AT. | 01/21/2010 |