| A dual-function SNF2 protein drives chromatid resolution and nascent transcripts removal in mitosis. | A dual-function SNF2 protein drives chromatid resolution and nascent transcripts removal in mitosis.
Carmo C, Coelho J, Silva RD, Tavares A, Boavida A, Gaetani P, Guilgur LG, Martinho RG, Oliveira RA., Free PMC Article | 09/11/2023 |
| CLOCK and TIMELESS regulate rhythmic occupancy of the BRAHMA chromatin-remodeling protein at clock gene promoters. | CLOCK and TIMELESS regulate rhythmic occupancy of the BRAHMA chromatin-remodeling protein at clock gene promoters.
Tabuloc CA, Cai YD, Kwok RS, Chan EC, Hidalgo S, Chiu JC., Free PMC Article | 03/8/2023 |
| In vivo analysis reveals that ATP-hydrolysis couples remodeling to SWI/SNF release from chromatin. | In vivo analysis reveals that ATP-hydrolysis couples remodeling to SWI/SNF release from chromatin.
Tilly BC, Chalkley GE, van der Knaap JA, Moshkin YM, Kan TW, Dekkers DH, Demmers JA, Verrijzer CP., Free PMC Article | 10/23/2021 |
| Osa-Containing Brahma Complex Regulates Innate Immunity and the Expression of Metabolic Genes in Drosophila. | Osa-Containing Brahma Complex Regulates Innate Immunity and the Expression of Metabolic Genes in Drosophila.
Valanne S, Järvelä-Stölting M, Harjula SE, Myllymäki H, Salminen TS, Rämet M. | 01/2/2021 |
| CDK-mediated phosphorylation of Brm is important in G1-S phase regulation and differentiation in vivo. | Phosphorylation of Drosophila Brahma on CDK-phosphorylation sites is important for cell cycle regulation and differentiation.
Roesley SNA, La Marca JE, Deans AJ, Mckenzie L, Suryadinata R, Burke P, Portela M, Wang H, Bernard O, Sarcevic B, Richardson HE., Free PMC Article | 11/9/2019 |
| SWI/SNF regulates half of its targets without the need of ATP-driven nucleosome remodeling by Brahma | SWI/SNF regulates half of its targets without the need of ATP-driven nucleosome remodeling by Brahma.
Jordán-Pla A, Yu S, Waldholm J, Källman T, Östlund Farrants AK, Visa N., Free PMC Article | 12/22/2018 |
| Examination of the epistatic relationship between candidate genes and Stat92E reveals that Ptp61F and brm interact with Stat92E during both border cell specification and migration. | Identification of Novel Regulators of the JAK/STAT Signaling Pathway that Control Border Cell Migration in the Drosophila Ovary.
Saadin A, Starz-Gaiano M., Free PMC Article | 11/18/2017 |
| Study characterizes the BRAHMA (BRM) chromatin-remodeling protein in Drosophila in the context of circadian clock regulation. By dissecting its catalytic vs. non-catalytic activities, we propose a model in which the non-catalytic activity of BRM functions to recruit repressive factors to limit the transcriptional output of CLK during the active phase of circadian transcription. | Understanding the role of chromatin remodeling in the regulation of circadian transcription in Drosophila.
Kwok RS, Lam VH, Chiu JC., Free PMC Article | 12/17/2016 |
| This paper identified the Brahma (Brm) complex as a regulator of the Drosophila clock | The Catalytic and Non-catalytic Functions of the Brahma Chromatin-Remodeling Protein Collaborate to Fine-Tune Circadian Transcription in Drosophila.
Kwok RS, Li YH, Lei AJ, Edery I, Chiu JC., Free PMC Article | 04/30/2016 |
| Data indicate that brahma protein (Brm) in the form of the PBAP complex functions in the germline stem cells (GSCs) fate regulation. | Evidence for chromatin-remodeling complex PBAP-controlled maintenance of the Drosophila ovarian germline stem cells.
He J, Xuan T, Xin T, An H, Wang J, Zhao G, Li M., Free PMC Article | 12/5/2015 |
| Brahma functions as a critical regulator of Hippo signaling during tissue growth and plays an important role in the feedback loop between Crb and Yki. | Brahma regulates the Hippo pathway activity through forming complex with Yki-Sd and regulating the transcription of Crumbs.
Zhu Y, Li D, Wang Y, Pei C, Liu S, Zhang L, Yuan Z, Zhang P. | 11/21/2015 |
| Brm-HDAC3-Erm repressor complex suppresses dedifferentiation of intermediate neural progenitors back into type II neuroblasts. | The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages.
Koe CT, Li S, Rossi F, Wong JJ, Wang Y, Zhang Z, Chen K, Aw SS, Richardson HE, Robson P, Sung WK, Yu F, Gonzalez C, Wang H., Free PMC Article | 11/14/2015 |
| findings highlighted the importance of Hpo signaling in regulating epigenetic components such as Brm to control downstream transcription and hence ISC proliferation | Brahma is essential for Drosophila intestinal stem cell proliferation and regulated by Hippo signaling.
Jin Y, Xu J, Yin MX, Lu Y, Hu L, Li P, Zhang P, Yuan Z, Ho MS, Ji H, Zhao Y, Zhang L., Free PMC Article | 04/4/2015 |
| The results show that Brm knockdown leads to nucleosome occupancy changes throughout the entire genome with a bias in occupancy decrease. | Drosophila Brahma complex remodels nucleosome organizations in multiple aspects.
Shi J, Zheng M, Ye Y, Li M, Chen X, Hu X, Sun J, Zhang X, Jiang C., Free PMC Article | 12/6/2014 |
| Results show that the levels of BRM affect specifically the abundance of a trans-spliced mod(mdg4) mRNA isoform in both S2 cells and larvae. | Brahma regulates a specific trans-splicing event at the mod(mdg4) locus of Drosophila melanogaster.
Yu S, Waldholm J, Böhm S, Visa N., Free PMC Article | 11/22/2014 |
| TnaA physically interacts with the SUMO E2 conjugating enzyme Ubc9, and with the BRM complex subunit Osa. | TnaA, an SP-RING protein, interacts with Osa, a subunit of the chromatin remodeling complex BRAHMA and with the SUMOylation pathway in Drosophila melanogaster.
Monribot-Villanueva J, Juárez-Uribe RA, Palomera-Sánchez Z, Gutiérrez-Aguiar L, Zurita M, Kennison JA, Vázquez M., Free PMC Article | 11/16/2013 |
| In the repressed state of the ftz-f1 gene, the Pol II complex is pre-recruited on the promoter; Pol II starts transcription but is paused 1.5 kb downstream of the promoter, with SAYP and Brahma forming a nucleosomal barrier ahead of paused Pol II. | SAYP and Brahma are important for 'repressive' and 'transient' Pol II pausing.
Vorobyeva NE, Nikolenko JV, Nabirochkina EN, Krasnov AN, Shidlovskii YV, Georgieva SG., Free PMC Article | 11/17/2012 |
| Novel conservative domain of SAYP coactivator mediates TFIID and Brahma transcriptional complexes interaction | [Novel conservative domain of SAYP coactivator mediates TFIID and Brahma transcriptional complexes interaction].
Vorob'eva NE, Soshnikova NV, Nikolenko IuV, Kuz'mina IuL, Nabirochkina EN, Georgieva SG, Shidlovskiĭ IuV. | 01/1/2011 |
| Gem and Brm act antagonistically to modulate the EGFR-Ras-MAPK signaling pathway, by affecting Mek levels during Drosophila development | Geminin and Brahma act antagonistically to regulate EGFR-Ras-MAPK signaling in Drosophila.
Herr A, Mckenzie L, Suryadinata R, Sadowski M, Parsons LM, Sarcevic B, Richardson HE. | 08/16/2010 |
| The existence of a stable coactivator supercomplex consisting of the chromatin-remodeling factor Brahma (SWI/SNF) and the transcription initiation factor TFIID, is shown. | Transcription coactivator SAYP combines chromatin remodeler Brahma and transcription initiation factor TFIID into a single supercomplex.
Vorobyeva NE, Soshnikova NV, Nikolenko JV, Kuzmina JL, Nabirochkina EN, Georgieva SG, Shidlovskii YV., Free PMC Article | 01/21/2010 |
| brahma chromatin-remodeling complexes interaction with gammaTub23C | gammaTub23C interacts genetically with brahma chromatin-remodeling complexes in Drosophila melanogaster.
Vázquez M, Cooper MT, Zurita M, Kennison JA., Free PMC Article | 01/21/2010 |
| complex facilitates global transcription by RNA polymerase II | The Drosophila BRM complex facilitates global transcription by RNA polymerase II.
Armstrong JA, Papoulas O, Daubresse G, Sperling AS, Lis JT, Scott MP, Tamkun JW., Free PMC Article | 01/21/2010 |
| Genetic screens for enhancers of brm reveal functional interactions between the brm chromatin-remodeling complex and the dNotch signal transduction pathway. | Genetic screens for enhancers of brahma reveal functional interactions between the BRM chromatin-remodeling complex and the delta-notch signal transduction pathway in Drosophila.
Armstrong JA, Sperling AS, Deuring R, Manning L, Moseley SL, Papoulas O, Piatek CI, Doe CQ, Tamkun JW., Free PMC Article | 01/21/2010 |
| Consistent with this view, SNR1(E1) is stably associated with other components of the Brm complex at the restrictive temperature. | The Drosophila SNR1 (SNF5/INI1) subunit directs essential developmental functions of the Brahma chromatin remodeling complex.
Marenda DR, Zraly CB, Feng Y, Egan S, Dingwall AK., Free PMC Article | 01/21/2010 |
| The abundant HMG box proteins HMGB AND HGMD participate in Brahma-dependent chromatin remodeling at a specific subset of Brahma-dependent promoters. | High mobility group proteins HMGD and HMGZ interact genetically with the Brahma chromatin remodeling complex in Drosophila.
Ragab A, Thompson EC, Travers AA., Free PMC Article | 01/21/2010 |