| HNRNPC Regulates GLUT1/LDHA Pathway by Stabilizing FOXM1 mRNA to Promote the Progression and Aerobic Glycolysis of Multiple Myeloma. | HNRNPC Regulates GLUT1/LDHA Pathway by Stabilizing FOXM1 mRNA to Promote the Progression and Aerobic Glycolysis of Multiple Myeloma.
Wu N, Zhu Y. | 04/4/2024 |
| Single-cell sequencing of the retina shows that LDHA regulates pathogenesis of autoimmune uveitis. | Single-cell sequencing of the retina shows that LDHA regulates pathogenesis of autoimmune uveitis.
Peng X, Li H, Zhu L, Zhao S, Li Z, Li S, DongtingWu, Chen J, Zheng S, Su W. | 04/3/2024 |
| Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression. | Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression.
Khan F, Lin Y, Ali H, Pang L, Dunterman M, Hsu WH, Frenis K, Grant Rowe R, Wainwright DA, McCortney K, Billingham LK, Miska J, Horbinski C, Lesniak MS, Chen P., Free PMC Article | 03/7/2024 |
| The opposite role of lactate dehydrogenase a (LDHA) in cervical cancer under energy stress conditions. | The opposite role of lactate dehydrogenase a (LDHA) in cervical cancer under energy stress conditions.
Jia C, Wu Y, Gao F, Liu W, Li N, Chen Y, Sun L, Wang S, Yu C, Bao Y, Song Z. | 03/6/2024 |
| Cytoplasmic localization of SETDB1-induced Warburg effect via c-MYC-LDHA axis enhances migration and invasion in breast carcinoma. | Cytoplasmic localization of SETDB1‑induced Warburg effect via c‑MYC‑LDHA axis enhances migration and invasion in breast carcinoma.
Yang W, Wei Y, Wang T, Xu Y, Jin X, Qian H, Yang S, He S., Free PMC Article | 03/5/2024 |
| Canonical Wnt signaling promotes HSC glycolysis and liver fibrosis through an LDH-A/HIF-1alpha transcriptional complex. | Canonical Wnt signaling promotes HSC glycolysis and liver fibrosis through an LDH-A/HIF-1α transcriptional complex.
Wang F, Chen L, Kong D, Zhang X, Xia S, Liang B, Li Y, Zhou Y, Zhang Z, Shao J, Zheng S, Zhang F., Free PMC Article | 03/1/2024 |
| LRPPRC promotes glycolysis by stabilising LDHA mRNA and its knockdown plus glutamine inhibitor induces synthetic lethality via m[6] A modification in triple-negative breast cancer. | LRPPRC promotes glycolysis by stabilising LDHA mRNA and its knockdown plus glutamine inhibitor induces synthetic lethality via m(6) A modification in triple-negative breast cancer.
Yu Y, Deng H, Wang W, Xiao S, Zheng R, Lv L, Wang H, Chen J, Zhang B., Free PMC Article | 02/29/2024 |
| Lactate dehydrogenase A promotes nasopharyngeal carcinoma progression through the TAK1/NF-kappaB Axis. | Lactate dehydrogenase A promotes nasopharyngeal carcinoma progression through the TAK1/NF-κB Axis.
Li Y, Chen L, Zheng Q, Liu G, Wang M, Wei S, Chen T. | 02/7/2024 |
| LncRNA DLEU2 contributes to Taxol resistance of gastric cancer cells through regulating the miR-30c-5p-LDHA axis. | LncRNA DLEU2 contributes to Taxol resistance of gastric cancer cells through regulating the miR-30c-5p-LDHA axis.
Xiang W, Zhang B, Li H. | 01/30/2024 |
| Identifying the critical oncogenic mechanism of LDHA based on a prognostic model of T-cell synthetic drivers. | Identifying the critical oncogenic mechanism of LDHA based on a prognostic model of T-cell synthetic drivers.
Wang G, Zheng H, Xiang Y, Wang Y, Wang K, Ren X, Du J. | 01/4/2024 |
| Combined inhibition of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase a induces metabolic and signaling reprogramming and enhances lung adenocarcinoma cell killing. | Combined inhibition of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase a induces metabolic and signaling reprogramming and enhances lung adenocarcinoma cell killing.
Zhou Y, Guo Y, Ran M, Shan W, Granchi C, Giovannetti E, Minutolo F, Peters GJ, Tam KY. | 12/5/2023 |
| The mRNA and protein levels of the glycolytic enzymes lactate dehydrogenase A (LDHA) and phosphofructokinase platelet (PFKP) are good predictors of survival time, recurrence, and risk of death in cervical cancer patients. | The mRNA and protein levels of the glycolytic enzymes lactate dehydrogenase A (LDHA) and phosphofructokinase platelet (PFKP) are good predictors of survival time, recurrence, and risk of death in cervical cancer patients.
Bolaños-Suárez V, Alfaro A, Espinosa AM, Medina-Martínez I, Juárez E, Villegas-Sepúlveda N, Gudiño-Zayas M, Gutiérrez-Castro A, Román-Bassaure E, Salinas-Nieves ME, Bruno-Muñoz S, Aranda C, Flores-Herrera O, Berumen J., Free PMC Article | 08/16/2023 |
| The novel role of LDHA/LDHB in the prognostic value and tumor-immune infiltration in clear cell renal cell carcinoma. | The novel role of LDHA/LDHB in the prognostic value and tumor-immune infiltration in clear cell renal cell carcinoma.
Chen J, Wu F, Cao Y, Xing Y, Liu Q, Zhao Z., Free PMC Article | 08/9/2023 |
| LDHA Desuccinylase Sirtuin 5 as A Novel Cancer Metastatic Stimulator in Aggressive Prostate Cancer. | LDHA Desuccinylase Sirtuin 5 as A Novel Cancer Metastatic Stimulator in Aggressive Prostate Cancer.
Kwon OK, Bang IH, Choi SY, Jeon JM, Na AY, Gao Y, Cho SS, Ki SH, Choe Y, Lee JN, Ha YS, Bae EJ, Kwon TG, Park BH, Lee S., Free PMC Article | 07/27/2023 |
| USP1 promotes the aerobic glycolysis and progression of T-cell acute lymphoblastic leukemia via PLK1/LDHA axis. | USP1 promotes the aerobic glycolysis and progression of T-cell acute lymphoblastic leukemia via PLK1/LDHA axis.
Liu S, Xiang Y, Wang B, Gao C, Chen Z, Xie S, Wu J, Liu Y, Zhao X, Yang C, Yue Z, Wang L, Wen X, Zhang R, Zhang F, Xu H, Zhai X, Zheng H, Zhang H, Qian M., Free PMC Article | 07/6/2023 |
| Nuclear Translocation of LDHA Promotes the Catabolism of BCAAs to Sustain GBM Cell Proliferation through the TxN Antioxidant Pathway. | Nuclear Translocation of LDHA Promotes the Catabolism of BCAAs to Sustain GBM Cell Proliferation through the TxN Antioxidant Pathway.
Li Z, Gu Z, Wang L, Guan Y, Lyu Y, Zhang J, Wang Y, Wang X, Xiong J, Liu Y., Free PMC Article | 06/13/2023 |
| PIM kinases phosphorylate lactate dehydrogenase A at serine 161 and suppress its nuclear ubiquitination. | PIM kinases phosphorylate lactate dehydrogenase A at serine 161 and suppress its nuclear ubiquitination.
Mung KL, Meinander A, Koskinen PJ. | 05/7/2023 |
| The SIX1/LDHA Axis Promotes Lactate Accumulation and Leads to NK Cell Dysfunction in Pancreatic Cancer. | The SIX1/LDHA Axis Promotes Lactate Accumulation and Leads to NK Cell Dysfunction in Pancreatic Cancer.
Ge W, Meng L, Cao S, Hou C, Zhu X, Huang D, Li Q, Peng Y, Jiang K., Free PMC Article | 03/27/2023 |
| Apolipoprotein L3 enhances CD8+ T cell antitumor immunity of colorectal cancer by promoting LDHA-mediated ferroptosis. | Apolipoprotein L3 enhances CD8+ T cell antitumor immunity of colorectal cancer by promoting LDHA-mediated ferroptosis.
Lv Y, Tang W, Xu Y, Chang W, Zhang Z, Lin Q, Ji M, Feng Q, He G, Xu J., Free PMC Article | 03/21/2023 |
| Glycolysis-related lncRNA TMEM105 upregulates LDHA to facilitate breast cancer liver metastasis via sponging miR-1208. | Glycolysis-related lncRNA TMEM105 upregulates LDHA to facilitate breast cancer liver metastasis via sponging miR-1208.
Han J, Chen X, Wang J, Liu B., Free PMC Article | 02/13/2023 |
| Circular RNA, circular RARS, promotes aerobic glycolysis of non-small-cell lung cancer by binding with LDHA. | Circular RNA, circular RARS, promotes aerobic glycolysis of non-small-cell lung cancer by binding with LDHA.
Li H, Huang Q, Guo H, Chen X, Li X, Qiu M., Free PMC Article | 02/11/2023 |
| Clinical, Biochemical, and Molecular Characterization of Two Families with Novel Mutations in the LDHA Gene (GSD XI). | Clinical, Biochemical, and Molecular Characterization of Two Families with Novel Mutations in the LDHA Gene (GSD XI).
Serrano-Lorenzo P, Rabasa M, Esteban J, Hidalgo Mayoral I, Domínguez-González C, Blanco-Echevarría A, Garrido-Moraga R, Lucia A, Blázquez A, Rubio JC, Palma-Milla C, Arenas J, Martín MA., Free PMC Article | 01/11/2023 |
| LDHA deficiency inhibits trophoblast proliferation via the PI3K/AKT/FOXO1/CyclinD1 signaling pathway in unexplained recurrent spontaneous abortion. | LDHA deficiency inhibits trophoblast proliferation via the PI3K/AKT/FOXO1/CyclinD1 signaling pathway in unexplained recurrent spontaneous abortion.
Zhu Y, Wu F, Hu J, Xu Y, Zhang J, Li Y, Lin Y, Liu X. | 01/11/2023 |
| Effect of LDHA Inhibition on TNF-alpha-Induced Cell Migration in Esophageal Cancers. | Effect of LDHA Inhibition on TNF-α-Induced Cell Migration in Esophageal Cancers.
Forkasiewicz A, Stach W, Wierzbicki J, Stach K, Tabola R, Hryniewicz-Jankowska A, Augoff K., Free PMC Article | 01/11/2023 |
| Upregulation of SCD1 by ErbB2 via LDHA promotes breast cancer cell migration and invasion. | Upregulation of SCD1 by ErbB2 via LDHA promotes breast cancer cell migration and invasion.
Chen J, Lv S, Huang B, Ma X, Fu S, Zhao Y. | 12/17/2022 |